Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, December 26, 2017

Stem Cell Therapy in Stroke

Note the word promising, not currently used. I  think stem cells are decades away from usefulness. Stem cell pushers are selling hope, not results.
https://link.springer.com/chapter/10.1007/978-981-10-5804-2_21

  • Yaying Song
    • 1
  • Guo-Yuan Yang
    • 1
  • Zhijun Zhang
    • 1
  1. 1.Med-X Research Institute and School of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina
Chapter
First Online:
  • 15 Downloads
Part of the Translational Medicine Research book series (TRAMERE)

Abstract

Stem cell-based treatment for ischemic stroke has shown its effectiveness in animal models and clinical trials. In this chapter, we describe different types and delivery routes of stem cells for therapy, the tracing of stem cells after delivery, and the clinical challenges and strategies in the future. Stem cells derived from various tissues have shown their beneficial role for functional recovery after stroke. Although the mechanism of stem cell-based therapy is not fully understood, it may include the releasing of growth factors, microenvironment regulation, and the preparation of repairing the blood-brain barrier integrity. Clinical applications of stem cell-based therapy are still in infancy. The future of clinical study in the stem cell-based therapy in the stroke field needs to focus on the modification of stem cells or combining different types of stem cells to enhance the therapeutic efficacy, mechanisms of stem cells action, and translation to clinical applications. Stem cell treatment is a promising regenerative therapeutic strategy because it can prevent neuronal cell apoptosis, inhibit pro-inflammatory cell recruitment, secrete multiple neurotropic factors, and promote neural differentiation.

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