Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Friday, August 18, 2017

Cholesterol crystals are sure sign a heart attack may loom

You'll have to ask your doctor how this can be prevented. I'm using the following.

Watermelon juice reverses hardening of the arteries Nov. 2011 

New study shows aged garlic extract can reduce dangerous plaque buildup in arteries  Jan. 2016 

Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation  June 2004 

Regular coffee drinkers have 'cleaner' arteries March 2015 

I'm not medically trained so don't follow me.

Cholesterol crystals are sure sign a heart attack may loom 

A new Michigan State University study on 240 emergency room patients shows just how much of a role a person's cholesterol plays, when in a crystallized state, during a heart attack.
George Abela, lead author and chief cardiologist at MSU, analyzed the material that was obstructing the coronary arteries of patients who had suffered a and found that 89 percent of them had an excessive amount of these crystallized structures, referred to as .
The research is now published online in the American Journal of Cardiology.
These crystals are released from plaque that can build up in the heart and is often made up of fat, calcium and other substances as well. When this material hardens over time in the arteries, it's known as atherosclerosis.
"In previous studies, we showed that when cholesterol goes from a liquid to a solid, or crystal state, it expands in volume like ice and water," Abela said. "This expansion inside the wall of the artery can tear it and block causing a heart attack or stroke."
After entered the , Abela and his team suctioned out this plaque. They were able to see that clusters of large crystals had formed and were able to break through the plaque and walls of the arteries and then released into the heart. This caused damage by blocking blood flow.
"We now know to what great extent these crystals are contributing to a heart attack," Abela said.
This latest research also reconfirms what Abela discovered in an earlier study that cholesterol crystals activated the production of inflammation molecules, known as Interleukin-1 beta, which aggravate, or inflame, coronary arteries.
"Now that we've shown how extensive cholesterol crystals are irritating and blocking off these , treatments that dissolve these crystals may be used to reduce heart damage," Abela said.
Some of these treatments can include the use of statin drugs - often used to lower one's cholesterol - aspirin and solvents such as alcohol that can be injected in low doses into a vein during a heart attack. Using these options could allow doctors to improve patient outcomes and save more lives.
A recent clinical trial using an already FDA-approved antibody, known as canakinumab, has also shown to block the Interleukin-1 beta inflammation molecule and reduce the chances of a cardiac event.
"Saving heart muscle is the most important aspect of treating a heart attack," Abela said. "So, if we are able to provide patients with better, more targeted treatments, then this could help open up and calm down the aggravated artery and protect the muscle from injury."
Abela also added that by simply controlling one's cholesterol by eating a healthy diet, exercising and taking statin medications as needed, could be the best way to prevent these crystals from forming.
More information: Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate during Acute Myocardial Infarction and Their Relation to Inflammation and Myocardial Injury , American Journal of Cardiology (2017). DOI: dx.doi.org/10.1016/j.amjcard.2017.07.075
Provided by Michigan State University


No comments:

Post a Comment