Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, December 10, 2017

Botanicals as Modulators of Neuroplasticity: Focus on BDNF

So to get better BDNF your doctor has to get you a diet protocol. Do you really think that will occur?  28 pages for your doctor to figure out.

Botanicals as Modulators of Neuroplasticity: Focus on BDNF

 

 Enrico Sangiovanni, Paola Brivio, Mario Dell’Agli, Francesca Calabrese
Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy
* Correspondence: Francesca Calabrese; Dept. Pharmacological and Biomolecular Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy; francesca.calabrese@unimi.it
Abstract: The involvement of Brain-derived neurotrophic factor (BDNF) in different central
nervous system (CNS) diseases suggests that this neurotrophin may represent an interesting and
reliable therapeutic target. Accordingly, the search for new compounds, also from natural sources,
able to modulate BDNF has been increasingly explored. The present review critically considers the
available literature on the effects of botanicals acting on CNS, focusing on BDNF. Botanicals
considered were: Bacopa monnieri (L.) Pennell, Coffea arabica L., Crocus sativus L., Eleutherococcus senticosus Maxim., Camellia sinensis (L.) Kuntze (green tea), Ginkgo biloba L., Hypericum perforatum L., Olea europea L. (olive oil), Panax ginseng C.A. Meyer, Rhodiola rosea L., Salvia miltiorrhiza Bunge, Vitis vinifera L., Withania somnifera (L.) Dunal, and Perilla frutescens (L.) Britton. The effect of the active principles responsible for the efficacy of the extracts is reviewed and discussed as well. The high number of articles published (more than one hundred manuscripts for 14 botanicals) supports the growing interest in the use of natural products as BDNF modulators. The studies reported herein strengthen the hypothesis that botanicals may be considered useful modulators of BDNF in CNS diseases (i.e. cognitive deficits), without high side effects. Further clinical studies
are mandatory to confirm botanicals as preventive agents or as useful adjuvant to the pharmacological treatment.
Keywords: cognition; depression

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