Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Thursday, January 11, 2018

Vitamin D Supplements May Make Arteries Healthier

Not to be done on your own, notice the toxic effects of large doses.
https://health.usnews.com/health-care/articles/2018-01-09/vitamin-d-supplements-may-make-arteries-healthier

By Dennis Thompson
HealthDay Reporter

(HealthDay)

TUESDAY, Jan. 9, 2018 (HealthDay News) -- High doses of vitamin D seem to keep arteries more flexible and pliable, potentially warding off future heart disease, heart attacks and strokes, preliminary research suggests.
In just four months, vitamin D supplements reduced arterial stiffness in a group of 70 young black men and women, according to results from a small-scale clinical trial.
The flexibility of participants' arteries improved even more with higher doses of vitamin D, said senior researcher Dr. Yanbin Dong, a professor with the Medical College of Georgia at Augusta University, in Augusta.
"Their arterial stiffness decreased, and the more vitamin D, the better," Dong said.
Vitamin D is known to be essential for bone health, but for the past couple of decades scientists have suspected it might be important in other ways, he said.
"The vitamin D receptor is expressed everywhere in your body, in almost every single type of cell," Dong said. "That's why people think vitamin D might have something more to offer."
To see if the vitamin might improve the health of blood vessels, Dong and his colleagues recruited a group of overweight or obese black Americans who were deficient in vitamin D.
Human skin naturally synthesizes vitamin D when exposed to bright sunshine. However, darker skin absorbs less sunlight, making black people more susceptible to vitamin deficiency, the researchers said.
In addition, body fat tends to capture and hold vitamin D, also contributing to deficiency.
The study participants were placed into four groups. Three groups took oral doses of vitamin D amounting to 600 international units (IU), 2,000 IU or 4,000 IU daily. The fourth group took inactive placebos.
The National Academy of Medicine currently recommends that people get 600 IU of vitamin D daily, Dong said. The researchers chose 2,000 IU because they suspected that might be the best dose, and 4,000 IU because that's the highest level before people start experiencing toxic effects.
Also, previous studies have shown that, taken daily, 2,000 IU and 4,000 IU doses of vitamin D can bring a vitamin-deficient person's levels of vitamin D back within a normal range, the study authors noted.
Those in the study who took 4,000 IU daily -- more than six times the currently recommended amount -- experienced a 10.4 percent reduction in arterial stiffness within four months, the findings showed.
Those who took 2,000 IU a day experienced a 2 percent decrease in arterial stiffness during the same timeframe. People who took the currently recommended dose of 600 IU had a slight increase in arterial stiffness -- about 0.1 percent. Those who took the placebos had a 2.3 percent increase, according to the report.
No toxic effects were observed among people who took the larger doses of the vitamin, Dong said.
Vitamin D might help arterial health by blocking a hormone system that increases constriction of blood vessels, the researchers said. It also helps reduce inflammation, which has been linked to hardened arteries.
Dong expects that some whites also would benefit from vitamin D supplementation.
"We expect we would see similar effects in white people who have similar vitamin D deficiency and are overweight," he said.
However, taking handfuls of vitamin D will not excuse a person from eating right or exercising for their heart health, Dong added.
"I don't think vitamin D should be an alternative for any other lifestyle modifications," Dong said. "We need to exercise, we need to eat sensibly. Vitamin D is just like anything else. It could be helpful on top of those things. It cannot replace."
These findings, however, present an opportunity to ward off heart disease in younger people at high risk, said Dr. Robert Eckel, director of the University of Colorado Hospital's Lipid Clinic.
Hardening of the arteries tends to be irreversible in older people who already have large amounts of arterial plaque as well as health problems such as diabetes and high cholesterol, Eckel said. This study, though, focused mainly on people in their 20s, he noted.
"Looking at vitamin D earlier in life -- before there's a lot of cardiovascular disease on board -- could be an encouraging improvement," said Eckel, who was not involved with the new study. "We're talking about primary prevention here."
The study participants should be tracked to see if their more flexible arteries translate to lower rates of heart disease and stroke later in life, Eckel said. Future trials should also examine the effects of vitamin D on other races and ethnic groups, he said.
The study was published online recently in the journal PLOS One.
More information
The U.S. Office of Dietary Supplements has more on vitamin D.
Copyright © 2018 HealthDay. All rights reserved.

No comments:

Post a Comment