http://informahealthcare.com/doi/abs/10.3109/13880200903062614
February 2010, Vol. 48, No. 2
,
Pages 151-157
(doi:10.3109/13880200903062614)
S. Intahphuak1, P. Khonsung2, A. Panthong2
1McCormick Faculty of Nursing, Payap University, Chiang Mai, Thailand
2Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
This study investigated some pharmacological properties of virgin coconut oil (VCO), the natural pure oil from coconut [Cocos nucifera Linn
(Palmae)] milk, which was prepared without using chemical or high-heat
treatment. The anti-inflammatory, analgesic, and antipyretic effects of
VCO were assessed. In acute inflammatory models, VCO showed moderate
anti-inflammatory effects on ethyl phenylpropiolate-induced ear edema in
rats, and carrageenin- and arachidonic acid-induced paw edema. VCO
exhibited an inhibitory effect on chronic inflammation by reducing the
transudative weight, granuloma formation, and serum alkaline phosphatase
activity. VCO also showed a moderate analgesic effect on the acetic
acid-induced writhing response as well as an antipyretic effect in
yeast-induced hyperthermia. The results obtained suggest
anti-inflammatory, analgesic, and antipyretic properties of VCO.
Read More: http://informahealthcare.com/doi/abs/10.3109/13880200903062614
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