Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, November 2, 2014

Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial

Look at that, a protocol for hand exercises that can be reviewed and commented on. For stroke we have jackshit, there is really nothing science-based about stroke rehab, it all seems to be 'Winging it'. You had better be comfortable with complete ambiguity because you are going to get nothing concrete except maybe they'll warn you that only 10% get to complete recovery. And they have no clue as to which 10% will make it. Of course apologists will remind us of their standard excuse, 'All strokes are different, all stroke recoveries are different'. I call bullshit on that and you will need to challenge whomever tells you that. There are 11 million stroke survivors a year, a massive number that could handle thousands of clinical trials every year.  We can find answers, we just have to put in place people who will look for answers rather than sitting on their asses waiting for someone else to solve the problem.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2814%2960998-3/abstract?rss=yes

Dr Sarah E Lamb DPhil a b Corresponding AuthorEmail Address, Esther M Williamson PhD a, Peter J Heine BSc b, Jo Adams PhD c, Sukhdeep Dosanjh PhD b, Melina Dritsaki PhD b, Matthew J Glover MSc d, Joanne Lord PhD d, Christopher McConkey MSc b, Vivien Nichols MSc b, Anisur Rahman PhD e, Martin Underwood MD b, Mark A Williams PhD a, on behalf of the Strengthening and Stretching for Rheumatoid Arthritis of the Hand Trial (SARAH) Trial Team

Summary

Background

Disease-modifying biological agents and other drug regimens have substantially improved control of disease activity and joint damage in people with rheumatoid arthritis of the hand. However, commensurate changes in function and quality of life are not always noted. Tailored hand exercises might provide additional improvements, but evidence is lacking. We estimated the effectiveness and cost-effectiveness of tailored hand exercises in addition to usual care during 12 months.

Methods

In this pragmatic, multicentre, parallel-group trial, at 17 National Health Service sites across the UK we randomly assigned 490 adults with rheumatoid arthritis who had pain and dysfunction of the hands and had been on a stable drug regimen for at least 3 months, to either usual care or usual care plus a tailored strengthening and stretching hand exercise programme. Participants were randomly assigned with stratification by centre. Allocation was computer generated and unmasked to participants and therapists delivering treatment after randomisation. Outcome assessors and all investigators were masked to allocation. Physiotherapists or occupational therapists gave the treatments. The primary outcome was the Michigan Hand Outcomes Questionnaire overall hand function score at 12 months. The analysis was by intention to treat. We calculated cost per quality-adjusted life-year. This trial is registered as ISRCTN 89936343.

Findings

Between Oct 5, 2009, and May 10, 2011, we screened 1606 people, of whom 490 were randomly assigned to usual care (n=244) or tailored exercises (n=246). 438 of 490 participants (89%) provided 12 month follow-up data. Improvements in overall hand function were 3·6 points (95% CI 1·5—5·7) in the usual care group and 7·9 points (6·0—9·9) in the exercise group (mean difference between groups 4·3, 95% CI 1·5—7·1; p=0·0028). Pain, drug regimens, and health-care resource use were stable for 12 months, with no difference between the groups. No serious adverse events associated with the treatment were recorded. The cost of tailored hand exercise was £156 per person; cost per quality-adjusted life-year was £9549 with the EQ-5D (£17 941 with imputation for missing data).

Interpretation

We have shown that a tailored hand exercise programme is a worthwhile, low-cost intervention to provide as an adjunct to various drug regimens. Maximisation of the benefits of biological and DMARD regimens in terms of function, disability, and health-related quality of life should be an important treatment aim.

Funding

UK National Institute of Health Research Health Technology Assessment Programme (NIHR HTA), project number 07/32/05.

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