Well, I'm doing it and while I'm living longer I'll be having the time of my life.
I however use it for many other reasons, not least of which is the social connections. Don't follow me, I'm not medically trained.
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Regular daily alcohol intake is best for heart health, study finds August 2018
Alcohol for these 12 reasons.
But this negative for your doctor to focus on. Don't follow me.
Moderate alcohol intake increases BP, stroke risk in men
April 5, 2019
In
a genetic epidemiological study, the assumed protective effect of
moderate alcohol consumption on CV events was noncausal, and any level
of alcohol consumption was associated with increased BP and stroke risk
in men.
“Using genetics is a novel way to assess the health effects of alcohol, and to sort out whether moderate drinking really is protective, or whether it’s slightly harmful,” Iona Y. Millwood, DPhil, from the Medical Research Council Population Health Research Unit at the University of Oxford, U.K., said in a press release. “Our genetic analyses have helped us understand the cause-and-effect relationships.”
The researchers analyzed 512,715 Chinese adults with documented levels of alcohol consumption
from the China Kadoorie Biobank and followed them for approximately 10
years. Outcomes of interest included ischemic stroke, intracerebral
hemorrhage and MI.
In addition, the researchers genotyped 161,498 participants for two variants that alter alcohol metabolism, ALDH2-rs671 and ADH1B-rs1229984.
Among the cohort, 33% of men and 2% of women reported drinking alcohol most weeks.
Drinking not protective
In men, according to self-reported alcohol intake, those who had one or two drinks per day (approximately 100 g per week) had lower risk for ischemic stroke, intracerebral hemorrhage and MI than those who drank more or those who drank not at all. However, genotype-predicted alcohol intake in men was not associated with a similar pattern, Millwood and colleagues wrote.
Rather, as genotype-predicted alcohol intake in men rose, so did risk
for ischemic stroke (RR per 280 g per week = 1.27; 95% CI, 1.13-1.43)
and especially for intracerebral hemorrhage (RR per 280 g per week =
1.58; 95% CI, 1.36-1.84), according to the researchers.
There was no relationship between genotype-predicted alcohol intake in men and MI risk (RR per 280 g per week = 0.96; 95% CI, 0.78-1.18).
Also in men, increases in usual alcohol intake and genotype-predicted alcohol intake corresponded with increases in BP (P < .0001 for all), according to the researchers.
In women, the genotypes did not predict elevated alcohol intake and were not associated with BP, stroke or MI, Millwood and colleagues wrote.
“There are no protective effects of moderate alcohol intake against stroke. Even moderate alcohol consumption increases the chances of having a stroke,” Zhengming Chen, DPhil, from the Clinical Trial Studies Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, said in the release. “The findings for heart attack were less clear-cut, so we plan to collect more evidence.”
“Using genetics is a novel way to assess the health effects of alcohol, and to sort out whether moderate drinking really is protective, or whether it’s slightly harmful,” Iona Y. Millwood, DPhil, from the Medical Research Council Population Health Research Unit at the University of Oxford, U.K., said in a press release. “Our genetic analyses have helped us understand the cause-and-effect relationships.”
In addition, the researchers genotyped 161,498 participants for two variants that alter alcohol metabolism, ALDH2-rs671 and ADH1B-rs1229984.
Among the cohort, 33% of men and 2% of women reported drinking alcohol most weeks.
Drinking not protective
In men, according to self-reported alcohol intake, those who had one or two drinks per day (approximately 100 g per week) had lower risk for ischemic stroke, intracerebral hemorrhage and MI than those who drank more or those who drank not at all. However, genotype-predicted alcohol intake in men was not associated with a similar pattern, Millwood and colleagues wrote.
In a genetic epidemiological study, the assumed
protective effect of moderate alcohol consumption on CV events was
noncausal, and any level of alcohol consumption was associated with
increased BP and stroke risk in men.
Source: Adobe Stock
There was no relationship between genotype-predicted alcohol intake in men and MI risk (RR per 280 g per week = 0.96; 95% CI, 0.78-1.18).
Also in men, increases in usual alcohol intake and genotype-predicted alcohol intake corresponded with increases in BP (P < .0001 for all), according to the researchers.
In women, the genotypes did not predict elevated alcohol intake and were not associated with BP, stroke or MI, Millwood and colleagues wrote.
“There are no protective effects of moderate alcohol intake against stroke. Even moderate alcohol consumption increases the chances of having a stroke,” Zhengming Chen, DPhil, from the Clinical Trial Studies Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, said in the release. “The findings for heart attack were less clear-cut, so we plan to collect more evidence.”
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