Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, February 4, 2020

Abbott to test its heart device against lifetime blood thinners for reducing stroke risk

 For those of you with atrial fibrillation, discuss with your doctor.

Abbott to test its heart device against lifetime blood thinners for reducing stroke risk


Abbott plans to launch a head-to-head study that puts its structural heart device up against a newer generation of blood thinners, testing its ability to lower the risk of strokes in people with atrial fibrillation.
The devicemaker’s Amplatzer Amulet occluder is designed to permanently block a small, naturally forming pouch that develops within the muscle wall of the heart’s left atrium. In people with an irregular pulse, this appendage can fail to drain completely with each heartbeat; the blood that pools there can form clots that, once loose and pumped out of the heart, can cause debilitating or fatal strokes.
The randomized study, dubbed CATALYST, will evaluate the device’s performance over at least two years compared to blood thinners known as non-vitamin K antagonist oral anticoagulants, or NOACs, and as an alternative to the lifetime regimens that currently serve as a standard-of-care for patients with AFib.


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This class of drugs includes blockbusters like Eliquis, Xarelto and Pradaxa, which are now recommended over warfarin in cardiology treatment guidelines.
"A device that can address a significant structural issue of the heart via a minimally invasive procedure would be a significant step forward for patients with atrial fibrillation eligible for long-term NOAC therapy," said the study’s principal investigator, Vivek Reddy, director of Cardiac Arrhythmia Services for The Mount Sinai Hospital.
RELATED: Abbott names new CFO shortly ahead of CEO transition


The Amplatzer Amulet occluder. (Abbott)
Starting next month, the study plans to enroll up to 2,650 participants at 150 global sites, measuring rates of ischemic strokes, embolisms or cardiovascular mortality, as well as major bleeding events. Delivered to the heart by a catheter, the Amplatzer Amulet previously received a CE mark in 2013.
"The CATALYST trial has the potential to provide data for the Amplatzer Amulet LAA Occluder that could change clinical practice by eliminating a lifetime need for blood thinners—reinforcing our mission of helping people live better lives through better health,” Neil Moat, chief medical officer of Abbott’s structural heart business, said in a statement.
Abbott estimates that the prevalence of atrial fibrillation will rise over the coming decade to at least 12.1 million cases, with strokes related to AFib being nearly twice as fatal compared to unrelated strokes.

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