Deans' stroke musings: Could Neurogenesis and Navigating Change Be Key to Cognitive Flexibility?

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, September 8, 2023

Could Neurogenesis and Navigating Change Be Key to Cognitive Flexibility?

This sounds extremely important to stroke recovery. What is your doctor doing to ensure you have this ability?

Do you prefer your doctor and hospital incompetence in this NOT KNOWING? OR NOT DOING?

Could Neurogenesis and Navigating Change Be Key to Cognitive Flexibility?

Summary: Researchers are closing in on the relationship between cognitive adaptability and adult neurogenesis. They developed a novel animal model to test cognitive flexibility by adding layers of complexity to a maze challenge. This revealed that gamma-radiation hindered cognitive adaptability and specific newly-generated neurons responded distinctively to the task. Aging and neurogenesis in the hippocampus, it seems, are deeply connected to cognitive flexibility.

Key Facts:

The study utilized an innovative maze test, wherein mice had to adapt to changing cues to locate a submerged platform.
Gamma-radiation exposure impacted cognitive flexibility without affecting the primary task learning, leading mice to search for the platform in its old location.
The relationship between cognitive flexibility and neurogenesis was further underscored with aging, indicating potential areas for therapeutic interventions.

Source: Stony Brook University

The ability to shift from one type of cognitive problem-solving strategy to another when the circumstances change, called cognitive adaptability or flexibility, is an essential function for humans. When this ability is diminished—whether by aging, disease, trauma, or environmental exposure—mental behavior becomes more inflexible and a person has difficulty adapting to new cognitive demands and remains stuck in the previous way of thinking.

The same adverse conditions—disease and aging—also affect the process of creating new neurons long after birth (called adult neurogenesis). However, the link between the two conditions remains elusive. A team of researchers led by Stony Brook University scientists believe they have a new understanding of cognitive adaptability and the role of adult neurogenesis.