Deans' stroke musings: Potential treatment strategies for enhancing neuroplasticity and regeneration after ischemic stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, May 15, 2012

Potential treatment strategies for enhancing neuroplasticity and regeneration after ischemic stroke

This summary is especially uninformative, so ask your doctor for the complete writeup.
http://www.futuremedicine.com/doi/full/10.2217/fnl.12.12

Strokes are a major cause of death and result in a drastic reduction in quality of life. Novel therapeutic strategies for patients suffering from stroke are thus required. Two possible strategies can be proposed for treating ischemic stroke: enhancing neuroplasticity, allowing the surviving neuronal cells to compensate for stroke-related impairment through brain reorganization, sprouting and rewiring of neuronal cells, or regeneration of neuronal cells, including enhancement of intrinsic neurogenesis and stem cell transplantation therapy with neural stem cells, embryonic stem cells or induced pluripotent stem cells. Endogenous neurogenesis or transplanted neural stem cells, embryonic stem cells or induced pluripotent stem cell-derived cells are able to not only supply newborn neurons integrated into a damaged neuronal network, but also produce growth factors into the recovering brains. These secretory factors enhance sprouting and angiogenesis and may be important in neuroplasticity and recovery in the poststroke brain.