Our stroke associations should be able to determine if the
pros of marijuana use for recovery are greater than the cons. But they won't because they have
NO strategy and NO leadership. Don't prescribe your own marijuana that would be dangerous. This research has little use for most stroke survivors since the age only went to 30.
http://www.ncbi.nlm.nih.gov/pubmed/26831916
Auer R1,
Vittinghoff E2,
Yaffe K3,
Künzi A4,
Kertesz SG5,
Levine DA6,
Albanese E7,
Whitmer RA8,
Jacobs DR Jr9,
Sidney S8,
Glymour MM2,
Pletcher MJ2.
Abstract
Importance:
Marijuana
use is increasingly common in the United States. It is unclear whether
it has long-term effects on memory and other domains of cognitive
function.
Objective:
To study the association between cumulative lifetime exposure to marijuana use and cognitive performance in middle age.
Design, Setting, and Participants:
We
used data from the Coronary Artery Risk Development in Young Adults
(CARDIA) study, a cohort of 5115 black and white men and women aged 18
to 30 years at baseline from March 25, 1985, to June 7, 1986 (year 0),
and followed up over 25 years from June 7, 1986, to August 31, 2011, to
estimate cumulative years of exposure to marijuana (1 year = 365 days of
marijuana use) using repeated measures and to assess associations with
cognitive function at year 25. Linear regression was used to adjust for
demographic factors, cardiovascular risk factors, tobacco smoking, use
of alcohol and illicit drugs, physical activity, depression, and results
of the mirror star tracing test (a measure of cognitive function) at
year 2. Data analysis was conducted from June 7, 1986, to August 31,
2011.
Main Outcomes and Measures:
Three
domains of cognitive function were assessed at year 25 using the Rey
Auditory Verbal Learning Test (verbal memory), the Digit Symbol
Substitution Test (processing speed), and the Stroop Interference Test
(executive function).
Results:
Among
3385 participants with cognitive function measurements at the year 25
visit, 2852 (84.3%) reported past marijuana use, but only 392 (11.6%)
continued to use marijuana into middle age. Current use of marijuana was
associated with worse verbal memory and processing speed; cumulative
lifetime exposure was associated with worse performance in all 3 domains
of cognitive function. After excluding current users and adjusting for
potential confounders, cumulative lifetime exposure to marijuana
remained significantly associated with worse verbal memory. For each 5
years of past exposure, verbal memory was 0.13 standardized units lower
(95% CI, -0.24 to -0.02; P = .02), corresponding to a mean of 1 of 2
participants remembering 1 word fewer from a list of 15 words for every 5
years of use. After adjustment, we found no associations with lower
executive function (-0.03 [95% CI, -0.12 to 0.07]; P = .56) or
processing speed (-0.04 [95% CI, -0.16 to 0.08]; P = .51).
Conclusions and Relevance:
Past
exposure to marijuana is associated with worse verbal memory but does
not appear to affect other domains of cognitive function.
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