Deans' stroke musings: Comparison of neuroplastic response to cathodal transcranial direct current stimulation and continuous theta burst stimulation in subacute stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, September 8, 2018

Comparison of neuroplastic response to cathodal transcranial direct current stimulation and continuous theta burst stimulation in subacute stroke

Big words, so useless in using this to communicate with your medical staff. No clear statement of what was accomplished and could be used in stroke rehab.

The Fugl-Meyer upper extremity scale has no objective distinction for changes in ability and thus would be useless as a measurement tool.

Comparison of neuroplastic response to cathodal transcranial direct current stimulation and continuous theta burst stimulation in subacute stroke

Archives of Physical Medicine and Rehabilitation , Volume 99(5) , Pgs. 862-872, 872.e1.

NARIC Accession Number: J79097. What's this?
ISSN: 0003-9993.
Author(s): Nicolo, Pierre; Magnin, Cecile; Pedrazzini, Elena; Plomp, Gijs; Mottaz, Anais; Schnider, Armin; Guggisberg, Adrian G..
Publication Year: 2018.
Number of Pages: 12.
Abstract: Study investigated the effects of cathodal transcranial direct current stimulation (tDCS) and continuous theta burst stimulation (cTBS) on neural network connectivity and motor recovery in individuals with subacute stroke. Forty-one subjects with stroke were randomly assigned to neuronavigated cTBS, cathodal tDCS, or sham transcranial magnetic stimulation/sham tDCS over the contralesional primary motor cortex (M1). Each subject completed 9 stimulation sessions over 3 weeks, combined with physical therapy. Brain function was assessed with directed and nondirected functional connectivity based on high-density electroencephalography before and after stimulation sessions. The primary clinical outcome measure was the change in slope of the multifaceted motor score composed of the upper-extremity Fugl-Meyer Assessment score, Box and Block test score, 9-Hole Peg Test score, and Jamar dynamometer results between the baseline period and the treatment time. Neither stimulation treatment enhanced clinical motor gains. Cathodal tDCS and cTBS induced different neural effects. Only cTBS was able to reduce transcallosal influences from the contralesional to the ipsilesional M1 during rest. Conversely, tDCS enhanced perilesional beta-band oscillation coherence compared with cTBS and sham groups. Correlation analyses indicated that the modulation of interhemispheric driving and perilesional beta-band connectivity were not independent mediators for functional recovery across all patients. However, exploratory subgroup analyses suggest that the enhancement of perilesional beta-band connectivity through tDCS might have more robust clinical gains if started within the first 4 weeks after stroke. The inhibition of the contralesional M1 or the reduction of interhemispheric interactions was not clinically useful in this heterogeneous group of subjects with subacute stroke. An early modulation of perilesional oscillation coherence seems to be a more promising strategy for brain stimulation interventions.
Descriptor Terms: BRAIN, DEXTERITY, ELECTRICAL STIMULATION, ELECTROPHYSIOLOGY, LIMBS, MOTOR SKILLS, PHYSICAL THERAPY, STROKE.

Can this document be ordered through NARIC's document delivery service*?: Not available from NARIC.

Citation: Nicolo, Pierre, Magnin, Cecile, Pedrazzini, Elena, Plomp, Gijs, Mottaz, Anais, Schnider, Armin, Guggisberg, Adrian G.. (2018). Comparison of neuroplastic response to cathodal transcranial direct current stimulation and continuous theta burst stimulation in subacute stroke. Archives of Physical Medicine and Rehabilitation , 99(5), Pgs. 862-872, 872.e1. Retrieved 9/8/2018, from REHABDATA database.