link.springer.com/chapter/10.1007/978-1-4614-8915-3_16#page-1
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Abstract
The immune response can
contribute to the risk of stroke as well as to brain injury following
stroke. Directed modulation of the immune response to attenuate risk or
injury is thus a potential therapeutic strategy for treating stroke.
Inducing a population of antigen-specific regulatory T cells is one such
strategy and can be used to locally modulate the immune response to the
organs in which the antigen is present, thereby limiting potential side
effects. This chapter addresses the use of mucosal tolerance to both
prevent and treat ischemic stroke.
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