We wouldn't need much research like this if we solved and prevented the
neuronal cascade of death.
http://www.ncbi.nlm.nih.gov/pubmed/25627292
Mayo NE1,
Anderson S2,
Barclay R3,
Cameron JI4,
Desrosiers J5,
Eng JJ6,
Huijbregts M7,
Kagan A8,
MacKay-Lyons M9,
Moriello C10,
Richards CL11,
Salbach NM7,
Scott SC12,
Teasell R13,
Bayley M14.
Abstract
OBJECTIVE:
To enhance participation post stroke through a structured, community-based program.
DESIGN:
A controlled trial with random allocation to immediate or four-month delayed entry.
SETTING:
Eleven community sites in seven Canadian cities.
SUBJECTS:
Community dwelling persons within five years of stroke onset, cognitively intact, able to toilet independently.
INTERVENTIONS:
Evidence-based
program delivered in three 12-week sessions including exercise and
project-based activities, done as individuals and in groups.
MAIN MEASURES:
Hours
spent per week in meaningful activities outside of the home and
Reintegration to Normal Living Index; Stroke-Specific Geriatric
Depression Scale, Apathy Scale, gait speed, EuroQuol EQ-5D, and
Preference-Based Stroke Index. All measures were transformed to a scale
from 0 to 100. Assessments prior to randomization, after the first
session at three months, six months, 12 months, and 15 months.
RESULTS:
A
total of 186 persons were randomized. The between-group analysis showed
no disadvantage to waiting and so groups were combined and a
within-person analysis was carried out at three time points. There were
statistically significant increases in all study outcomes on average
over all persons. Over 45% of people met or exceeded the pre-specified
target of a three hour per week increase in meaningful activity and this
most often took a full year of intervention to achieve. Greatest gains
were in satisfaction with community integration (mean 4.78; 95% CI: 2.01
to 7.55) and stroke-specific health-related quality of life (mean 4.14;
95% CI: 2.31 to 5.97).
CONCLUSIONS:
Community-based
programs targeting participation are feasible and effective, but stroke
survivors require time to achieve meaningful gains.
No comments:
Post a Comment