Will your competent? doctor and hospital get this implemented as a protocol in your hospital in the next week? Your risk of epilepsy here and solutions:
10% seizures post stroke (19 posts to April 2017)
5% epileptic seizures after stroke (10 posts to April 2021)
epileptic seizures (6 posts to December 2015)
post-stroke epilepsy (7 posts to December 2016)
Just maybe you want your doctor to try these solutions.
Cannabidiol May Reduce Seizures by Half in Hard-to-treat Epilepsy
Or maybe the nasal spray referred to in here:
Preventing Seizure-Caused Damage to the Brain
The answers are out there, does your doctor know about them?
Mozart may reduce seizure frequency in people with epilepsy
The latest here:
Blood pressure drug may lower risk for post-stroke epilepsy
Key takeaways:
- Angiotensin receptor blockers were linked to a reduced risk for post-stroke epilepsy vs. other antihypertension medications.
- PSE incidence was highest for calcium channel blockers and beta blockers.
LOS ANGELES — Individuals with hypertension and stroke who were prescribed angiotensin receptor blockers had a significantly lower risk for post-stroke epilepsy than those prescribed other antihypertension medications, according to new research.
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| Patients with hypertension and stroke who were prescribed ARBs had a significantly lower risk for post-stroke epilepsy than those prescribed other antihypertension medications, according to new research. Image: Adobe Stock |
“Our study uniquely focused on how effective different blood pressure medications are at
preventing PSE in the real world,” Giacomo Evangelista, MD, PhD, study co-lead author and neurology resident at the Epilepsy Center at G. d’Annunzio University of Chieti-Pescara, Italy, said in a release related to the study, presented at the American Epilepsy Society annual meeting. “Understanding which antihypertensive medications help prevent
complications such as PSE can lead to better patient outcomes.”
According to the European Society of Cardiology, angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) can be considered effective first-line hypertension treatments to protect against seizures; however, it is unknown whether these drugs may assume a preventive role in post-stroke epilepsy (PSE), which occurs in roughly 6% to 8% of those with ischemic stroke.
Evangelista and colleagues investigated the efficacy of ARBs as an antihypertensive treatment for prevention of PSE in a retrospective, observational study. The study was conducted between January 2016 and January 2022 and included 528 individuals (57.2% men) diagnosed with hypertension and ischemic stroke confirmed by clinical and neuroimaging evaluations. The patients did not have epilepsy at the time of stroke but were taking some form of blood pressure medication.
A total of 194 patients were taking two or more antihypertension medications: 164 were prescribed beta-blockers (20 with PSE); 159 were prescribed calcium channel blockers (15 with PSE); 154 were prescribed ACEi (10 with PSE); 136 were prescribed diuretics (8 with PSE), and 109 were prescribed ARBs (3 with PSE), according to the release.
All participants were followed for a mean period of 66 months.
According to the results, 38 (7.2%) individuals developed PSE.
The researchers found that, compared with patients who took ARBs, the likelihood of developing PSE was:
- 120% higher among those who took beta-blockers;
- 110% higher among those who took calcium channel blockers;
- 65% higher among those who took ACEi; and
- 60% higher among those who took diuretics.
“These findings highlight the importance of personalized medicine, particularly in managing blood pressure in stroke patients,” Fedele Dono, MD, MSc, FEBN, co-lead author of the study and colleague of Evangelista at the Epilepsy Center, G. d’Annunzio University of Chieti-Pescara. “Further research in more patients is necessary to confirm these findings and explore the underlying mechanisms in more detail.”
Reference:
Common Blood Pressure Drug May Help Reduce Increased Risk of Epilepsy after a Stroke. https://aesnet.org/about/aes-press-room/press-releases/common-blood-pressure-drug--may-help-reduce-increased-risk-of-epilepsy-after-a-stroke. Published Dec. 6, 2024. Accessed Dec. 7, 2024.
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