http://journals.sagepub.com/doi/abs/10.1177/1545968317744277
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Antonia F. Ten Brink, MSc 12
, Johanna M. A. Visser-Meily, PhD 12
, Martijn J. Schut, MSc 3
,
1University Medical Center Utrecht, Netherlands2De Hoogstraat Rehabilitation, Utrecht, Netherlands
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1University Medical Center Utrecht, Netherlands2De Hoogstraat Rehabilitation, Utrecht, Netherlands
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3Utrecht University, Netherlands
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Mirjam Kouwenhoven, MD 2
, Anja L. H. Eijsackers, MSc 2
, Tanja C. W. Nijboer, PhD 13
...
2De Hoogstraat Rehabilitation, Utrecht, Netherlands
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2De Hoogstraat Rehabilitation, Utrecht, Netherlands
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1University Medical Center Utrecht, Netherlands3Utrecht University, Netherlands
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Article Information
Article first published online: December 1, 2017
https://doi.org/10.1177/1545968317744277
Antonia F. Ten Brink, MSc 1, 2, Johanna M. A. Visser-Meily, PhD 1, 2, Martijn J. Schut, MSc 3, Mirjam Kouwenhoven, MD 2, Anja L. H. Eijsackers, MSc 2, Tanja C. W. Nijboer, PhD 1, 3
1University Medical Center Utrecht, Netherlands
2De Hoogstraat Rehabilitation, Utrecht, Netherlands
3Utrecht University, Netherlands
Corresponding Author: Tanja C. W. Nijboer, PhD, Department of Experimental Psychology, Utrecht University, Heidelberglaan 1, 3584 CS, Utrecht, Netherlands. Email: t. c. w. nijboer@uu. nl
Abstract
Background. Patients with neglect ignore or respond slower to contralesional stimuli. Neglect negatively influences independence in activities of daily living (ADL). Prism adaptation (PA) is one of the most frequently studied treatments, yet there is little evidence regarding positive effects on neglect behavior in ADL.
Objective. To assess whether PA in the subacute phase ameliorates neglect in situations of varying complexity.
Methods. A total of 70 neglect patients admitted for inpatient stroke rehabilitation received either PA or sham adaptation (SA) for 2 weeks, with full access to standard treatment. There were 7 time-dependent measurements (baseline and 1-4, 6, and 14 weeks after start of treatment). The primary outcome was change of neglect as observed during basic ADL with the Catherine Bergego Scale (CBS). Secondary outcomes were changes in performance on a dynamic multitask (ie, the Mobility Assessment Course [MAC]) and a static paper-and-pencil task (ie, a shape cancellation task [SC]). Results. In all, 34 patients received PA and 35 SA. There were significant time-dependent improvements in performance as measured with the CBS, MAC, and SC (all F > 15.57; P < .001). There was no significant difference in magnitude of improvement between groups on the CBS, MAC, and SC (all F < 2.54; P > .113].
Conclusions. No beneficial effects of PA over SA in the subacute phase poststroke were observed, which was comparable for situations of varying complexity. Heterogeneity of the syndrome, time post–stroke onset, and the content of treatment as usual are discussed. Basic knowledge on subtypes and recovery patterns would aid the development of tailored treatment.
Objective. To assess whether PA in the subacute phase ameliorates neglect in situations of varying complexity.
Methods. A total of 70 neglect patients admitted for inpatient stroke rehabilitation received either PA or sham adaptation (SA) for 2 weeks, with full access to standard treatment. There were 7 time-dependent measurements (baseline and 1-4, 6, and 14 weeks after start of treatment). The primary outcome was change of neglect as observed during basic ADL with the Catherine Bergego Scale (CBS). Secondary outcomes were changes in performance on a dynamic multitask (ie, the Mobility Assessment Course [MAC]) and a static paper-and-pencil task (ie, a shape cancellation task [SC]). Results. In all, 34 patients received PA and 35 SA. There were significant time-dependent improvements in performance as measured with the CBS, MAC, and SC (all F > 15.57; P < .001). There was no significant difference in magnitude of improvement between groups on the CBS, MAC, and SC (all F < 2.54; P > .113].
Conclusions. No beneficial effects of PA over SA in the subacute phase poststroke were observed, which was comparable for situations of varying complexity. Heterogeneity of the syndrome, time post–stroke onset, and the content of treatment as usual are discussed. Basic knowledge on subtypes and recovery patterns would aid the development of tailored treatment.
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