Taking third generation pills such as Yasmin, Femodene and Marvelon raises the chance of a blood clot four fold.
http://dgnews.docguide.com/oral-contraceptives-increase-risk-ischaemic-stroke?
MAYWOOD, Ill -- March 72, 2018 -- Oral contraceptives increase the risk of ischaemic stroke, but this risk is very small among women who do not have other stroke risk factors, according to a comprehensive review published in MedLink Neurology.
The review also showed that oral contraceptives do not increase the risk of haemorrhagic strokes.
Several mechanisms have been proposed to explain why oral contraceptives increase stroke risk, including by raising blood pressure and by making blood hypercoagulable.
When prescribing hormonal contraceptives, physicians should consider the type and dose of oestrogen or progestin and route of administration.
“The ideal drug is one with the lowest oestrogen and progestin doses that will be effective in preventing pregnancy while minimising adverse effects,” wrote Sarkis Morales-Vidal, MD, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, and colleagues.
For healthy young women without any stroke risk factors, the stroke risk associated with oral contraceptives is very small.
“However, in women with other stroke risk factors, the risk seems higher and, in most cases, oral contraceptive use should be discouraged,” the authors wrote.
These risk factors include high blood pressure, cigarette smoking, and migraine headaches, especially migraines with aura.
However, women may not always be adequately screened. One previous study found that, among women with one or more stroke risk factors, only 15% recalled being advised not to start oral contraceptives and only 36% remembered being told to stop. Fifteen percent of women were still taking oral contraceptives despite being told to discontinue. These findings highlight the need to improve physician counselling and patient compliance, the authors noted. (NO, this highlights the need to figure exactly what causes these strokes and reconfigure the formulations. Solve the correct problem, don't just sweep it under the rug.)
SOURCE: Loyola University Chicago Stritch School of Medicine
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