Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, May 18, 2019

Nano-featured poly (lactide-coco-glycolide)-graphene microribbons as a promising substrate for nerve tissue engineering

What leader in stroke is going to look at this and say? 'We need researchers to find a use for this in stroke recovery.' It will never occur, we have NO LEADERS IN STROKE.  

Of course nothing was done with these earlier posts on this back to July 2012. We have complete and total fucking incompetency in the stroke medical world. And until we get survivors in charge, NOTHING WILL BE ACCOMPLISHED.

 

Nano-featured poly (lactide-coco-glycolide)-graphene microribbons as a promising substrate for nerve tissue engineering

Abstract

In this research, nanocomposite poly (lactide-coco-glycolide)-Graphene (PLGA-Gr) microribbons were developed for neural tissue engineering. Moreover, the effects of Gr concentration (0, 0.1, 0.5 and 1 wt %) on the chemical and physical structure, mechanical properties, thermal stability and biological properties were evaluated. Our findings proved that incorporation of graphene nanosheets in the PLGA matrix resulted in the formation of aligned groove-shaped roughness on the surface of microribbons. In addition, Gr nanosheets could significantly promote the electrical conductivity and hydrophilicity of PLGA microribbons. In addition, the tensile strength and elastic modulus of the PLGA-Gr microribbons significantly promoted (upon 2 times and more than 3 times, respectively) compared to PLGA microribbons. The results demonstrated enhanced differentiation rate of SH-SY5Y cells to mature neurons on PLGA-Gr compared to PLGA. In summary, our findings discovered that aligned PLGA-Gr microribbons presented appropriate chemical, physical and mechanical properties to promote neuroblastoma cells. It is anticipated that the offered PLGA scaffolds might have great potential to develop a favorable construct for central nerve regeneration. However, further biological in vivo studies are required to assess the role of PLGA-Gr microribbons on the nerve regeneration.

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