I'm not elderly yet but this sounds like a useful stroke rehab item. One of my falls in the hospital was the first night in a regular room. I woke up around 2am needing to go to the bathroom, thinking I was at my parents house I knew the bathroom was just down the hall. I think I managed 1 step and collapsed on the floor. That earned me the dreaded yellow wrist band, high risk of falls, and the catheter.
http://www.rawstory.com/rs/2012/05/01/scientists-have-pinpointed-nighttime-urination-protein-in-elderly/
Scientists have pinpointed a protein that helps explain why the
elderly frequently have to get up in the night to urinate, a problem
that can badly interfere with sleep.
Deficient levels of protein called connexin43 trick the bladder into
believing that it is full, which sends a “must urinate” warning to the
brain, they report on Tuesday in the journal Nature Communications.
Connexin43 is part of a cascade of proteins in the so-called
circadian clock — the complex mechanism by which body processes crank up
during daylight and slow down at night.
During
sound sleep, a healthy person produces a smaller volume of urine from
the kidneys than during daytime. At the same time, more urine is stored
during sleep than during the active, daylight phase.
But when there are lower levels of connexin43, the smooth muscles of
the bladder become oversensitised to nerve signals that give a feeling
of fullness, the study says.
Researchers led by Osamu Ogawa of Kyoto University made the discovery
among lab mice that had been genetically modified to lack the gene that
makes connexin43.
The team developed an automated system, using a roll of filter paper
that turned purple when exposed to even tiny amounts of fluid, to count
how often the caged rodents urinated at night.
The chronic need to urinate at night, a condition called nocturnal enuresis, also causes bedwetting by young children.
The researchers say there are likely to be other circadian pathways that are involved in the problem.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 28,972 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Friday, May 4, 2012
Scientists have pinpointed nighttime urination protein in elderly
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