Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, December 10, 2023

Impact of Poststroke Fracture on Quality of Life: Insights From a Retrospective Cohort Study

You do know it is abundantly obvious that the prevention of this problem is 100% RECOVERY PROTOCOLS? Or are you that much of a blithering idiot? I take no prisoners in trying to solve stroke, you shouldn't either, call them what they are; INCOMPETENT!

Impact of Poststroke Fracture on Quality of Life: Insights From a Retrospective Cohort Study

  • Qinglan “Priscilla” Ding, MBBS, PhD @QDing3
Originally published 10.1161/blog.20231120.39709

Dalli LL, Borschmann K, Cooke S, Kilkenny MF, Andrew NE, Scott D, Ebeling PR, Lannin NA, Grimley R, Sundararajan V, et al. Fracture Risk Increases After Stroke or Transient Ischemic Attack and Is Associated With Reduced Quality of Life. Stroke. 2023.

Stroke survivors face a multitude of challenges on their road to recovery, and recent research has shed light on a particularly concerning issue: an increased risk of fractures among this population. While some factors contributing to this elevated risk, such as age, gender, medications, and comorbidities, have been identified, a comprehensive understanding of how stroke affects fracture rates and its subsequent impact on health-related quality of life (HRQoL) has remained elusive.

In a pivotal contribution to the field, Dalli et al. conducted a retrospective cohort study that not only compared the annualized fracture rate before and after stroke or transient ischemic attack (TIA), but also delved into the intricate relationship between fracture and HRQoL. Their data, drawn from the Australian Stroke Clinical Registry (AuSCR), provided valuable insights from 13,594 adult survivors of stroke or TIA (49.7% were aged >=75 years, 45.5% were female, and 47.9% were unable to walk on admission).

The study’s findings were compelling, revealing a stark increase in fracture rates following stroke or TIA, with a 63% (95% CI, 47%-80%) relative rise in fracture in the year following the event. Hip fractures emerged as the most common type in both stroke and TIA cohorts, and a staggering 86% of poststroke fractures were attributed to falls. While some risk factors for fractures overlapped between stroke and TIA cohorts, such as age, gender, prior fractures, and comorbidities, there were notable distinctions. For instance, hypertension was associated with a reduced fracture incidence after TIA, and patients receiving care in a stroke unit had a 33% lower fracture risk. The impact on HRQoL was profound, with patients who experienced fractures reporting worsened HRQoL in various dimensions, including mobility, self-care, usual activities, and pain/discomfort. These findings translated into a clinically meaningful 0.11-point reduction in overall health status per EQ-5D-3L utility scores.

In essence, this study not only reaffirmed the heightened fracture risk poststroke, but also emphasized the urgent need to address this issue(You do that with 100% recovery protocols, nothing less!) to enhance the quality of life among stroke survivors. Poststroke fractures increase mortality and contribute to dependence, mobility challenges, and the need for residential care. To mitigate this concerning trend, comprehensive fall risk screening and preventive strategies are imperative after stroke and TIA. Moreover, the unique risk factors identified in this study should serve as a foundation for future research to unravel the underlying mechanisms behind falls in these patients. The striking finding that females are nearly 50% more likely to experience poststroke fractures than men underscores the importance of gender-specific interventions. Exploring evidence-based approaches, such as weight-bearing exercises and osteoporosis treatments like bisphosphonates, is crucial in reducing fracture risks among female stroke survivors.

As the number of stroke survivors living longer continues to rise, their quality of life becomes an increasingly important concern. As highlighted in this study, the negative impact of poststroke fractures on HRQoL affects multiple aspects of survivors’ lives. It carries significant implications for individuals, families, and society at large. Addressing this issue through tailored programs and longitudinal studies to monitor HRQoL changes over time is essential to improve the well-being of stroke survivors and enhance our understanding of this critical aspect of their recovery journey.


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