Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Wednesday, August 9, 2017

Alzheimer's disease could be reversed using LED lights, according to an MIT study on mice

Even though you are likely to go down the dementia route, you are not to try this on your own. You'll just have to wait until you are dead before this research is proven in humans.

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.
2. Then this study came out and seems to have a range from 17-66%. December 2013.
3. A 20% chance in this research.   July 2013.

Your doctor can compare this to this from April 2016

Light Improves Alzheimer's in More Ways than One

Or this from November 2015;

Using light to treat Alzheimer's disease

 

 The newest one here.


http://www.businessinsider.com/led-lights-might-be-the-key-to-stopping-alzheimers-2017-8
Symptoms of Alzheimer's affecting patient's memories could be reversed, new research from MIT indicates.
It might be possible to break down the genetic blockades inside the brain which cause memory loss from Alzheimer's, a study published in Cell Reports suggests. So far, the theory has only been tested on mice but lead author Li-Huei Tsai is hopeful that eventually, it could be successful in reversing the symptom in humans.
Memory loss is a form of cognitive decline which occurs when the enzyme HCAC2 compresses the brain's memory genes until they are rendered useless which, in turn, leads to forgetfulness and difficulty forming memories.
Whilst the obvious solution is to simply block  HCAC2 in action, doing so has proven difficult without impacting other HDAC enzymes, which affect the internal organs.
MIT's approach differs in that it exclusively affects HCAC2, leaving other enzymes undisturbed, something which has not yet been achieved.
Tsai succeeded in blocking the enzyme in December using LED lights, which prevented it from binding with Sp3, a genetic binding partner that is an integral part of genetic blockade formation.
"This is exciting because for the first time we have found a specific mechanism by which HDAC2 regulates synaptic gene expression," Tsai explained.
"If we can remove the blockade by inhibiting HDAC2 activity or reducing HDAC2 levels, then we can restore expression of all these genes necessary for learning and memory," she said.
The research is still in its early stages and has a long way to go until an official remedy comes to fruition.
However, it is the most revolutionary research to date in finding something close to a cure for Alzheimer's, the most common form of dementia which currently affects 850,000 people in the UK.
Read the original article on The Independent. Copyright 2017. Follow The Independent on Twitter.


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