For decades it was believed that brain regeneration was not possible. But an accumulating body of research now reveals that common foods such as broccoli contain compounds capable of stimulating the repair and renewal of nerve tissue.
Up-regulation of nuclear factor erythroid 2-related factor 2 (Nrf2), which increases innate antioxidant mechanisms.
Suppressing of interleukin-1b (IL-1b), to exert its anti-inﬂammatory eﬀects.
The Promising Study Results
“In summary, we demonstrated that the crucifer-derived SFN can eﬀectively stimulate NSC proliferation and diﬀerentiation by modifying genes in Wnt signaling pathway. Due to its lipophilic property and low molecular weight, SFN has a high bioavailability as an orally administered drug (Houghton, Fassett, & Coombes, 2013). SFN represents a food-derived compound that has been successfully translated from lab bench to clinics. (Bahadoran et al., 2012). It can be expected that SFN would see a shorter clinical path toward the market. Our data indicate that SFN is not only an Nrf2 inducer, but also a Wnt activator, which places SFN in a category distinct from other phytochemicals. The eﬀects of SFN in restoring Wnt signaling provides a wealth of opportunities for the treatment of stem-cell-related diseases characterized by suppressed Wnt signaling. Further clinical studies are warranted to corroborate the neuroprotective eﬀects of SFN in patients.”