Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:

Thursday, May 11, 2017

Higher Levels of Biomarker Linked to Increased Stroke Risk for Women

So fucking what? No solution is proposed if women have this biomarker other than further studies needed. Problems should never be described without at least a proposed solution.
MINNEAPOLIS, Minn -- May 10, 2017 -- Women with elevated levels of beta-2 microglobulin may be at a higher risk of ischaemic stroke, according to a study published in the May 10, 2017, online issue of Neurology.
“Recent studies have found associations between beta-2 microglobulin and heart disease,” said Pamela Rist, Brigham and Women’s Hospital, and Harvard Medical School, Boston, Massachusetts. “However, less is known about the association between beta-2 microglobulin and ischaemic stroke.”
The researchers looked at women with a mean age of 61 years enrolled in the Nurses’ Health Study who provided blood samples between 1989 and 1990 and who had no history of stroke or cancer. Participants were asked to complete questionnaires about their lifestyle and medical history every 2 years.
To learn more about beta-2 microglobulin and any possible link to stroke, the researchers measured the protein levels in 473 study participants who later had an ischaemic stroke as well as 473 participants of the same age who did not have a stroke. They were also matched based on other factors that could affect stroke risk, such as whether they smoked or used hormone treatments. The strokes occurred an average of 9 years after the start of the study.
Results showed that participants who later had an ischaemic stroke had higher levels of beta-2 microglobulin than those who did not have a stroke. The average level of the protein was 1.86 mg/L in those who had ischaemic strokes, compared with 1.80 mg/L in those who did not have a stroke.
The researchers divided the participants into 4 groups based on their levels of the protein. Those in the highest quarter of beta-2 microglobulin levels were 56% more likely to have a stroke than those in the bottom quarter. In the top quarter, 163 of the 283 women had strokes, compared with 106 of the 227 women in the bottom quarter.
The results were adjusted for other factors that could affect stroke risk, such as physical activity, high blood pressure and diabetes.
Rist said that limitations of the study are that it was conducted mainly among white women and that it could not examine any changes in protein levels.
“Given the high rate of disability from stroke, it is important to identify people who may be at higher risk of this disease,” she said. “This protein could be a marker that might help us in the fight against stroke. Further studies are needed to determine if beta-2 microglobulin levels can be modified through lifestyle changes.”
SOURCE: American Academy of Neurology

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