Deans' stroke musings: Beneficial effects of young coconut juice on preserving neuronal cell density, lipid, renal and liver profiles in ovariectomized rats. A preliminary study

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, May 6, 2017

Beneficial effects of young coconut juice on preserving neuronal cell density, lipid, renal and liver profiles in ovariectomized rats. A preliminary study

Tested in rats so don't jump to conclusions. Ask your doctor when clinical research on humans will be done.
http://rdo.psu.ac.th/sjstweb/journal/39-2/39-2-12.pdf

Kolip Payanglee

, Pennapa Chonpathompikunlert

, Thammarat Panityakul

and Nisaudah Radenahmad

Department of Anatomy, Faculty of Science,

Prince of Songkla University,

Hat Yai, Songkhla, 90112 Thailand

Department of Physiology, Faculty of Science,

Prince of Songkla University,

Hat Yai, Songkhla, 90112 Thailand

Department of Mathemetics and Statistics, Faculty of Science,

Prince of Songkla University,

Hat Yai, Songkhla, 90112 Thailand

Received: 4 March 2016; Revised: 4 May 2016; Accepted: 20 May 2016

Abstract

Our previous study showed that young coconut juice (YCJ) at a high dose of 100 mL/kgBW had many health benefitse.g. it delayed Alzheimer’s pathologies, preserved neuronal cells, accelerated wound healing and prevented osteoporosis.

However, such a large dose of YCJ over a period of time started to have unfavourable side effects e.g. the deposition of glycogen in the liver. Therefore, our aim in the present study was to investigate the lowest neuroprotective dose of YCJ that would cause the least side effects for long-term consumption by postmenopausal women, using ovariectomized (ovx) rats as a model for postmenopausal women. Three lower doses of YCJ (10, 20 and 40 mL/kg body weight) were applied. The results clearly showed that the OY10 group was the best dose to help to preserve neuronal cells in both the hippocampus and the prefrontal cortex with cell numbers being higher than for the ovx group at various degrees of significance in each brain region.

After 10 weeks of treatment, the circulating levels of BUN, creatinine, cholesterol, triglyceride, HDL, LDL, AST, ALT, ALP, total protein, albumin, calcium and phosphorus of the OY10 group were not significantly different from those of the sham and ovx groups. This study has confirmed that feeding YCJ had beneficial effects on the serum lipid profile, and maintained liver and renal functions for up to 10 weeks after administration. YCJ consumption at 10 mL/kgBW/day for 10 weeks, however, did increase body weight and serum glucose when compared with the control groups. Therefore, supplementation with YCJ in postmenopausal women with a diabetic condition should only be allowed under supervision by a physician.