Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Sunday, May 7, 2017

Non-O blood groups at increased risk for CV events

Rather useless to know since we can't change our blood type, pretty much a fucking waste of research dollars. I'm O-negative so that didn't save me from having a CV event.
http://www.healio.com/cardiology/vascular-medicine/news/online/%7Bb27e3ce3-1a44-49d8-93b7-9195bd08b8be%7D/non-o-blood-groups-at-increased-risk-for-cv-events?
Individuals with non-O blood groups were at an increased risk for coronary events and combined CV events, according to findings presented at Heart Failure 2017 in Paris.
“It has been suggested that people with non-O blood groups (A, B, AB) are at higher risk for [MI] and overall [CV] mortality, but this suggestion comes from case-control studies, which have a low level of evidence,” Tessa Kole, a master’s degree student at the University Medical Centre Groningen in the Netherlands, said in a press release. “If this was confirmed, it could have important implications for personalized medicine.”
Kole and colleagues conducted a meta-analysis of prospective studies with more than 1.3 million participants combined. The researchers looked at associations between blood type and all coronary events, combined CV events and fatal coronary events.
There were 23,154 CV events in total. In the analysis of coronary events, 1.5% (n = 11,437) of people with non-O blood had a coronary event vs. 1.4% (n = 7,220) of participants with O blood (OR = 1.09; 95% CI, 1.06-1.13).
For combined CV events, 2.5% (n = 17,449) of participants with non-O blood had an event vs. 2.3% (n = 10,916) of those with O blood (OR = 1.09; 95% CI, 1.06-1.11).
There was no significant association between risk for fatal coronary event and blood type (OR = 1; 95% CI, 0.85-1.18).
“More research is needed to identify the cause of the apparent increased [CV] risk in people with a non-O blood group,” Kole said in the release. “Obtaining more information about risk in each non-O blood group (A, B and AB) might provide further explanations of the causes.”
Possible mechanisms include higher concentration of von Willebrand factor and increased rates of dyslipidemia in individuals with non-O blood, Kole and colleagues wrote in an abstract. – by Cassie Homer
Reference:
Kole T, et al. Abstract 697. Presented at: Heart Failure 2017 and the 4th World Congress on Acute Heart Failure; April 29-May 2, 2017; Paris.

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