How many decades before your doctor uses the flavonoid database to come up with a diet stroke protocol with it?
NEVER I BET. Just proving how incompetent s/he is.
Dietary flavonoid intake and incident coronary heart disease: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study
Abstract
BACKGROUND:
Flavonoids
are dietary polyphenolic compounds with a variety of proposed
beneficial cardiovascular effects, but rigorous prospective studies that
examine the association between flavonoid intake and incident coronary
heart disease (CHD) in geographically and racially diverse US samples
are limited.
OBJECTIVE:
With
the use of the new, expanded USDA flavonoid database, we assessed the
association between total flavonoid and flavonoid subclass intakes with
incident CHD in a biracial and geographically diverse cohort, as well as
effect modification by age, sex, race, and region of residence.
DESIGN:
Participants
were 16,678 black and white men and women enrolled in the REGARDS
(REasons for Geographic and Racial Differences in Stroke) study, a
national prospective cohort study. All participants were without CHD at
baseline, and all completed a Block98 food-frequency questionnaire.
Flavonoid intakes were estimated from USDA flavonoid databases, which
were recently improved to address missing values for cooked foods and to
adjust for flavonoid losses due to processing. Incident CHD events were
participant reported and adjudicated by experts. Quintiles of flavonoid
intake were examined as predictors of incident CHD by using Cox
proportional hazards regression to obtain HRs. Tests for trend used the
quintile medians.
RESULTS:
Over
a mean ± SD follow-up of 6.0 ± 1.9 y, there were 589 CHD events. High
flavonoid intake was associated with self-identified white race,
exercise, not smoking, more education, and higher income. In models that
adjusted for sociodemographic, health behavior, and dietary factors,
there was an inverse association between anthocyanidin and
proanthocyanidin intakes and incident CHD (HRs for quintile 5 compared
with quintile 1-anthocyanidins: 0.71; 95% CI: 0.52, 0.98; P-trend =
0.04; proanthocyanidins: 0.63; 95% CI: 0.47, 0.84; P-trend = 0.02).
There was no association between total flavonoid or other flavonoid
subclass intakes and incident CHD.
CONCLUSIONS:
Reported
anthocyanidin and proanthocyanidin intakes were inversely associated
with incident CHD. There was no significant effect modification by age,
sex, race, or region of residence.
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