Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Tuesday, April 4, 2017

Induced neural stem cells could promote stroke recovery, prevent damage

Since early is not defined here, the most likely reason for improvement is spontaneous recovery rather than these stem cells. Does no one understand how to design research properly or make proper conclusions from research?  A great stroke association president would be calling out these people to make sure they know what they are doing.
http://www.fiercebiotech.com/research/induced-neural-stem-cells-could-promote-stroke-recovery-prevent-damage
New research out of Japan has demonstrated that induced neural stem cells can help patients recover after a stroke and possibly, when administered early, prevent some of the most severe damage altogether.
Induced neural stem cells, or iNSCs, are somatic cells that have been directly differentiated into neural stem cells, as opposed to pluripotent stem cells, which can differentiate into a number of final products. Scientists from Okayama University found that these iNSCs might be more tolerable in vivo than pluripotents because they derive from the somatic cells without extra steps in between.
In mice with ischemic stroke, the iNSCs exerted a therapeutic effect and promoted functional recovery. What’s more, the cells also protected the brain from ischemia-related damage when administered during the early stages of a stroke.
The researchers published their findings in the journal Cell Transplantation.
“We observed multiple therapeutic effects when using these cells to treat stroke in mice,” Okayama’s Dr. Koji Abe said in a statement. “The iNSCs did not produce any adverse responses in the animals, including tumor formation, which may suggest they are safer than regular iPSCs. Further studies are needed to confirm this cell type as a candidate for cell replacement therapy for stroke.”

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