Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Sunday, April 16, 2017

Study Links Brain Structure, Anxiety and Negative Bias in Healthy Adults

With a 28% rate of generalized anxiety disorder in stroke survivors your doctor should have a protocol to address that. 
 You have one hell of a lot of anxiety about getting to 100% recovery since your doctor doesn't tell you how to do that.
http://neurosciencenews.com/anxiety-brain-structure-6405/ 
Summary: According to researchers, healthy people with a smaller inferior frontal cortex are more prone to anxiety and tend to view neutral events negatively.
Source: University of Illinois at Urbana Champaign.
Healthy college students who have a relatively small inferior frontal cortex – a brain region behind the temples that helps regulate thoughts and emotions – are more likely than others to suffer from anxiety, a new study finds. They also tend to view neutral or even positive events in a negative light, researchers report.
The researchers evaluated 62 students, collecting brain structural data from neuroimaging scans and using standard questionnaires to determine their level of anxiety and predilection for negative bias.
Previous studies of people diagnosed with anxiety have found similar correlations between the size of the IFC and anxiety and negative bias, said U. of I. psychology postdoctoral researcher Sanda Dolcos, who led the study with graduate student Yifan Hu. But the new findings, reported in the journal Social Cognitive and Affective Neuroscience, are the first to see these same dynamics in healthy adults, the researchers said.
“You would expect these brain changes more in clinical populations where anxiety is very serious, but we are seeing differences even in the brains of healthy young adults,” Dolcos said.
The study also found that the relationship between the size of the IFC and a student’s negative bias was mediated by their level of anxiety.
“People who have smaller volumes have higher levels of anxiety; people who have larger IFCs tend to have lower levels of anxiety,” Dolcos said. And higher anxiety is associated with more negative bias, she said. “How we see this is that the higher volume of the IFC confers resilience.”
“We found that larger IFC volume is protecting against negative bias through lower levels of trait anxiety,” Hu said.
According to the American College Health Association, anxiety is rampant on college campuses, where nearly 60 percent of students report at least one troubling bout of anxious worry every year.
Image shows the location of the inferior frontal cortex in the human brain.
The study also found that the relationship between the size of the IFC and a student’s negative bias was mediated by their level of anxiety. NeuroscienceNews.com image is for illustrative purposes only.
“There is a very high level of anxiety in the student population, and this is affecting their life, their academic performance, everything,” Dolcos said. “We are interested in identifying what is going on and preventing them from moving to the next level and developing clinical anxiety.”
Anxiety can interfere with many dimensions of life, causing a person to be on high alert for potential problems even under the best of circumstances, Hu said. Negative bias also can interfere with a person’s commitment to activities that might further their life goals, she said.
Understanding the interrelatedness of brain structure, function and personality traits such as anxiety and their behavioral effects such as negative bias will help scientists develop interventions to target specific brain regions in healthy populations, Hu said.
“We hope to be able to train the brain to function better,” she said. “That way, we might prevent these at-risk people from moving on to more severe anxiety.”
About this neuroscience research article
Funding: The Brain and Behavior Research Foundation and Health Minds Canada supported this research.
Source: Diana Yates – University of Illinois at Urbana Champaign
Image Source: NeuroscienceNews.com image is in the public domain.
Original Research: Full open access research for “Trait anxiety mediates the link between inferior frontal cortex volume and negative affective bias in healthy adults” by Yifan Hu and Sanda Dolcos in Social Cognitive and Affective Neuroscience. Published online March 1 2017 doi:10.1093/scan/nsx008
Cite This NeuroscienceNews.com Article
University of Illinois at Urbana Champaign “Study Links Brain Structure, Anxiety and Negative Bias in Healthy Adults.” NeuroscienceNews. NeuroscienceNews, 13 April 2017.
<http://neurosciencenews.com/anxiety-brain-structure-6405/>.

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