Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:

Thursday, January 5, 2017

Adult neurogenesis beyond the niche: its potential for driving brain plasticity

Ask your doctor how you are going to use this information in your protocols to get to 100% recovery.  Asking for that should not be a surprise to your doctor, it should be the default mode every stroke doctor strives for. They should have protocols for every stroke deficit you have. If all they do is write three prescriptions to PT, ST and OT for E.T.(Evaluate and Treat) then you have a doctor that knows absolutely nothing about your recovery. You will need to figure out your recovery completely on your own.

As Dr. Steven Wolf writes, a rehabilitation stroke expert and professor at Emory University School of Medicine in Atlanta.  "Stroke patients need to rely more on their own problem solving to regain mobility". 


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Non-neurogenic adult circuits structurally remodel with specific manipulations.
Neurogenic zones provide cues and synaptic partners for newborn neurons.
Neurogenesis demands massive structural remodeling of preexisting network.
Millions of new connections are made/exchanged each day for new adult-born neurons.
Adult neurogenesis may have more far-reaching role in general brain plasticity.

Adult neurogenesis emerges as a tremendous form of plasticity with the continuous addition and loss of neurons in the adult brain. It is unclear how preexisting adult circuits generated during development are capable of modifying existing connections to accommodate the thousands of new synapses formed and exchanged each day. Here we first make parallels with sensory deprivation studies and its ability to induce preexisting non-neurogenic adult circuits to undergo massive reorganization. We then review recent studies that show high structural and synaptic plasticity in circuits directly connected to adult-born neurons. Finally, we propose future directions in the field to decipher how host circuits can accommodate new neuron integration and to determine the impact of adult neurogenesis on global brain plasticity


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