- For the purpose of this study, 88 clinically healthy subjects (68 F; 20 M; mean age: 50.7 ± 12.9) were randomly allocated to Mediterranean (Med) or Vegetarian (Veg) isocaloric diets lasting 3 months each, and then crossed over.
- After that, adherence to the specific dietary intervention was established through questionnaires and 24–h dietary recall.
- Finally, anthropometric measurements, body composition and blood sampling were obtained from each member toward the start and toward the finish of each intervention phase.
- At the end of the 3–months intervention phase, Med and Veg both determined a significant (p<0.05) decrease of total body weight, fat mass and BMI, without any significant difference between the 2 diets [body weight: –2.0 kg (–2.5%) vs. –2.4 kg (–3.0%)], [fat mass: –1.8 kg (–6.1%) vs. –1.6 kg (–5.6%)] [BMI: –0.7 kg/m2 (–2.4%) vs. –0.8 kg/m2 (–2.8%)], for Med and Veg, respectively.
- With regard to circulating biomarkers, Veg determined a significant (p<0.05) diminish for total cholesterol [–6.0 mg/dL (–2.9%)], LDL cholesterol [–6.5 mg/dl (–5.1%)] and insulin levels [–0.7 mU/L (–6.9%)], while Med determined a significant decrease of triglycerides [–11 mg/dL (–8.9%)].