Your doctor should be coming back to you after this conference with some new ideas.
TransportDEMENTIA – treating dementia by activating the waste disposal system of the brain
09 December 2015 — 11 December 2015
University of Oslo, Faculty of Medicine
Meeting of the world-leading experts in research on
alternative strategies for dementia treatment and diagnostics in Oslo,
December 9-11This week more than 45 world-leading experts in the research field on transport proteins of the brain will meet at a special conference at Holmenkollen. The conference is financed by the Norges Forskingsrådet and the University of Oslo / Oslo University Hospital with the aim to establish Norway as the lead country in basic and translational research of the brain’s ABC transporters in dementia.
The experts have been invited by Prof. Jens Pahnke, internationally renowned Alzheimer’s disease researcher and the first to introduce these transporters for the therapy of dementia and movement disorders. The experts will discuss and present most recent results of their research projects. The meeting will be used to establish further collaboration projects led by Norwegian institutions.
Facts:
In 2011, ABC transporters were described as a new mechanism to explain the development of brain diseases with protein deposition, such as Alzheimer’s disease and Parkinson’s diseases. If the function of ABC transporters is reduced, dementia will develop. It was found that the function is reduced by 28% in demented elderly versus normal elderly and activation may serve as a new treatment strategy.
Since then, progress has been made and currently new treatment options have been tested. In 2016 the first Phase II study that uses an ABC transporter-activating compound will start. Currently, there are alternatives from traditional medicine that activate ABC transporters in the brain vessels and that can be used for the treatment of dementia patients. The University of Oslo / Oslo University Hospital is the world-wide leading centre for translational ABC transporter research in dementia that drives different internationally funded research projects.
http://pahnkelab.eu
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