Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Wednesday, February 15, 2017

Speed, Ecstasy Accelerate Heart Aging

Maybe  you want to accelerate aging  in order to recover from your stroke. But ask your doctor for details. I know nuthin.

Can ecstasy treat the agony of PTSD?

‘Ecstasy’ as a social drug: MDMA preferentially affects responses to emotional stimuli with social content

Study reveals how ecstasy acts on the brain and hints at therapeutic uses

A ‘Party Drug’ May Help the Brain Cope With Trauma - Ecstasy

 

 

 



http://www.medpagetoday.com/PublicHealthPolicy/PublicHealth/63049?

  • by
    Contributing Writer, MedPage Today
  • This article is a collaboration between MedPage Today® and:
    Medpage Today
Abuse of amphetamines was associated with premature biological aging in a way that was more aggressive than tobacco smoking, according to a single-center study.
After adjusting for multiple variables, amphetamine users had prematurely aging hearts as measured by arterial stiffness (P<0.0001), according to the study published online in Heart Asia.
And the biological age-to-chronological age slope was steeper with amphetamines than among tobacco user, Albert Stuart Reece, MD, and colleagues of the University of Western Australia, and colleagues reported.
"The process seems to occur more aggressively than with tobacco smoking," they wrote. "It appears to follow a different time course to that of the positive methadone control group."
"The implication from the present work is that recurrent habitual amphetamine abuse ages the cardiovasculature, and likely the whole organism generally. It is therefore conceivable that stimulant abusers do physiological and cardiovascular harm," they suggested.
Most (94%) users used amphetamines such as "speed," "ice," and "ecstasy" in the previous week; almost half (47%) reported use the day prior.
"These results show that subacute exposure to amphetamines is associated with an advancement of cardiovascular-organismal age both over age and over time, and is robust to adjustment," Reece's group wrote, although they admitted that they lacked dosage data.
Accelerated aging declined with time since last amphetamine use.
Asked by MedPage Today to provide comment, Matthias Liechti, MD, MAS, of University of Basel in Switzerland, argued that this shows that at least part of the "so-called aging" is simply vasoconstriction.
"Although chronic amphetamine use seems unlikely to benefit the circulation, I am not convinced that these changes are chronically lasting -- at least not the ones shown in this study," he wrote in an email.
Reece and colleagues included 713 patients in their study: 55 amphetamine users, 107 tobacco smokers, 483 non-smokers, and 68 methadone patients. The investigators measured heart age by radial arterial pulse tonometry (the SphygmoCor monitoring system).
Liechti questioned whether it was possible to control for all the lifestyle and health factors associated with amphetamine use, such as tobacco smoking. "In a between-subject study, such as the present one, it is difficult to control for these factors. So the changes in the vasculature, if at all of a lasting nature, may rather be linked to factors associated with amphetamine use disorder rather than reflect a lasting problem of the substance itself."
"Also note, that ADHD children use amphetamine daily and for years and they do not seem to suffer from any vascular problems," he added.
He conceded that the same cannot be said confidently for d-amphetamine and mixed amphetamines, however.
Reece and Liechti declared no conflicts of interest.
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