Ginger Supplementation Improves Inflammation, Metabolic Health, and Weight Control

 

 Is your doctor competent enough to get the dietician to incorporate these into the diet protocol at the hospital and your take home diet protocol ? NO? So, your doctor failed at that task! What are YOU going to do about that incompetence? Let it pass? Or pay it forward and get someone competent in the hospital for the next stroke survivor?

Ginger Supplementation Improves Inflammation, Metabolic Health, and Weight Control

3 Ways to Protect Your Working Memory as You Age by Super Age

 Did your competent? doctor give you anything even minutely close to this? NO? So, incompetence reigned? And your doctor suffers nothing from incompetence, but you do? But they still get paid for nothing, right?

3 Ways to Protect Your Working Memory as You Age

 Any mention of 'care' rather than recovery means a COMPLETELY FUCKING FAILURE OF A HOSPITAL; DON'T GO THERE!

UPMC Harrisburg Achieves Highest Level Of Stroke Care Certification

Health

28 May 2026 3:44 am AEST

UPMC Harrisburg Achieves Highest Level Of Stroke care(NOT RECOVERY!) CertificationHARRISBURG, Pa. - UPMC has been recognized for its ability to receive and treat central Pennsylvania's most complex stroke cases. The Joint Commission and American Stroke Association named UPMC Harrisburg a Comprehensive Stroke Center, their highest level of stroke Health

28 May 2026 3:44 am AEST

UPMC Harrisburg Achieves Highest Level Of Stroke Care Certification

HARRISBURG, Pa. - UPMC has been recognized for its ability to receive and treat central Pennsylvania's most complex stroke cases. The Joint Commission and American Stroke Association named UPMC Harrisburg a Comprehensive Stroke Center, their highest level of stroke care certification.

The new designation reflects an upward progression in UPMC Harrisburg's clinical capabilities and quality measures for advanced stroke care(NOT RECOVERY!), including care offered 24 hours a day, seven days a week, with onsite access to a variety of neurosurgical and vascular procedures, such as the ground-breaking mechanical thrombectomy and aneurysm clipping.

"Time is of the essence when responding to a stroke," said Dr. Bart Thaci, director of neuroendovascular care(NOT RECOVERY!), UPMC Neurological Institute, UPMC Harrisburg. "Comprehensive Stroke Center designation is evidence that our patients have timely and quality access to a variety of lifesaving of neurosurgical and neuroendovascular procedures."

In stroke care(NOT RECOVERY!), "time is brain," which means getting treatment quickly can reverse or mitigate possible damage and could save a patient's life. UPMC Carlisle, UPMC Community Osteopathic, UPMC Hanover, UPMC Lititz, UPMC Memorial, and UPMC West Shore are all designated as primary stroke centers and work with Stat MedEvac, UPMC Community Life Team, and other local emergency medical services (EMS) agencies to diagnose and treat strokes, and if necessary, quickly transfer them to UPMC Harrisburg for life-saving endovascular or neurosurgical procedures.

UPMC Harrisburg achieved Thrombectomy-Capable Stroke Center certification in 2024. And to date, UPMC doctors have performed more than 375 thrombectomy procedures. UPMC continues to develop a robust stroke program in central Pennsylvania, utilizing state-of-the-art technologies like artificial intelligence programs and tele-neurosurgical consults to identify patients who could benefit from procedures available at UPMC Harrisburg, UPMC's hub for advanced stroke care(NOT RECOVERY!) in central Pennsylvania.

"Stroke care(NOT RECOVERY!) is a team effort and our recognition as a Comprehensive Stroke Center shows that our UPMC employees are committed to limiting the devastating impacts of strokes for our patients," said Elizabeth Ritter, president, UPMC Harrisburg, UPMC Community Osteopathic, and UPMC West Shore. "Years of hard work and careful collaboration between our neurology, neurosurgery, emergency medicine and critical care(NOT RECOVERY!) teams; UPMC Community Life Team and local EMS providers; and Stat MedEvac partners, makes this achievement possible so we can show up for our community when the worst happens."

UPMC's commitment to stroke care(NOT RECOVERY!) doesn't end when patients are discharged from the hospital. Through their stroke clinics in Harrisburg, Mechanicsburg and Lancaster, patients have access to the care(NOT RECOVERY!) and education they need to recover from and prevent future strokes. Nurse navigators work individually with stroke survivors to ensure they are getting follow-up care(NOT RECOVERY!), treatments, and referrals to other medical specialists who can help them adjust to life after a stroke and prevent future strokes from happening.

"I'm proud of our care(NOT RECOVERY!) teams and their commitment to our patients and the community," said Kimberly Rinehart, executive administrator, UPMC Neurological Institute. "UPMC staff and community partners across our region work every day to respond to, treat, and help patients recover from strokes, and we thank them for their efforts."(So, proud of failure; you're fired!)

Learn more about stroke care at UPMC. certification.(So, still a failure since you tell us nothing about 100% recovery!)

The new designation reflects an upward progression in UPMC Harrisburg's clinical capabilities and quality measures for advanced stroke care(NOT RECOVERY!), including care(NOT RECOVERY!) offered 24 hours a day, seven days a week, with onsite access to a variety of neurosurgical and vascular procedures, such as the ground-breaking mechanical thrombectomy and aneurysm clipping.

"Time is of the essence when responding to a stroke," said Dr. Bart Thaci, director of neuroendovascular care(NOT RECOVERY!), UPMC Neurological Institute, UPMC Harrisburg. "Comprehensive Stroke Center designation is evidence that our patients have timely and quality access to a variety of lifesaving of neurosurgical and neuroendovascular procedures."

In stroke care(NOT RECOVERY!), "time is brain," which means getting treatment quickly can reverse or mitigate possible damage and could save a patient's life. UPMC Carlisle, UPMC Community Osteopathic, UPMC Hanover, UPMC Lititz, UPMC Memorial, and UPMC West Shore are all designated as primary stroke centers and work with Stat MedEvac, UPMC Community Life Team, and other local emergency medical services (EMS) agencies to diagnose and treat strokes, and if necessary, quickly transfer them to UPMC Harrisburg for life-saving endovascular or neurosurgical procedures.

UPMC Harrisburg achieved Thrombectomy-Capable Stroke Center certification in 2024. And to date, UPMC doctors have performed more than 375 thrombectomy procedures. UPMC continues to develop a robust stroke program in central Pennsylvania, utilizing state-of-the-art technologies like artificial intelligence programs and tele-neurosurgical consults to identify patients who could benefit from procedures available at UPMC Harrisburg, UPMC's hub for advanced stroke care(NOT RECOVERY!) in central Pennsylvania.

"Stroke care(NOT RECOVERY!) is a team effort and our recognition as a Comprehensive Stroke Center shows that our UPMC employees are committed to limiting the devastating impacts of strokes for our patients," said Elizabeth Ritter, president, UPMC Harrisburg, UPMC Community Osteopathic, and UPMC West Shore. "Years of hard work and careful collaboration between our neurology, neurosurgery, emergency medicine and critical care teams; UPMC Community Life Team and local EMS providers; and Stat MedEvac partners, makes this achievement possible so we can show up for our community when the worst happens."

UPMC's commitment to stroke care(NOT RECOVERY!) doesn't end when patients are discharged from the hospital. Through their stroke clinics in Harrisburg, Mechanicsburg and Lancaster, patients have access to the care(NOT RECOVERY!) and education they need to recover from and prevent future strokes. Nurse navigators work individually with stroke survivors to ensure they are getting follow-up care(NOT RECOVERY!), treatments, and referrals to other medical specialists who can help them adjust to life after a stroke and prevent future strokes from happening.

"I'm proud of our care(NOT RECOVERY!) teams and their commitment to our patients and the community," said Kimberly Rinehart, executive administrator, UPMC Neurological Institute. "UPMC staff and community partners across our region work every day to respond to, treat, and help patients recover from strokes, and we thank them for their efforts."

Learn more about stroke care at UPMC.

Mobile Stroke Units Enable Hyperacute Interventions for Intracerebral Hemorrhage

 Are they fast enough to get 100% recovery? If not; COMPLETE FUCKING FAILURE!

 The only goal in stroke is 100% recovery; if you're not there, GET THE HELL OUT OF STROKE! I take no prisoners in getting stroke solved, so if not following me; GET LOST!

Mobile Stroke Units Enable Hyperacute Interventions for Intracerebral Hemorrhage

Casandra MacLeod, DO, MS https://orcid.org/0009-0002-6918-3274 macleoc@ccf.org, Andrew Zhang, MD https://orcid.org/0000-0002-7801-8310, Nicolas Thompson, MS https://orcid.org/0000-0002-8973-5219, Elham Askari, MD, Merry Huang, MD, Nicholas Koroneos, DO, Maureen Buttrick, BSN, RN, … Show All … , and Jason Mathew, DO https://orcid.org/0000-0002-5862-687XAuthor Info & Affiliations

Stroke

New online

https://doi.org/10.1161/STROKEAHA.125.053752

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Abstract

BACKGROUND:

Mobile stroke units (MSUs) aim to expedite acute stroke management when compared with conventional emergency medical services (EMS). Despite the growing body of evidence surrounding MSUs and acute ischemic stroke, experience with intracerebral hemorrhage (ICH) in MSUs has been lacking. We aimed to evaluate the impact of MSU transportation, compared with EMS, on times to diagnosis and goal-directed treatment in patients with ICH.

METHODS:

Retrospective analysis of patients with acute ICH triaged by MSU or EMS from January 2018 to December 2022 was performed at 2 tertiary institutions, the Cleveland Clinic (OH) and Stony Brook University (NY). In the EMS cohort, only patients seen between 08:00 and 20:00, corresponding to the operating hours of MSU, were included. Primary outcomes included diagnosis by computed tomography, administration of antihypertensives, and time to goal systolic blood pressure (<160 mm Hg). Analyses included descriptive statistics and multivariable regression modeling of log-transformed time metrics, adjusting for important patient demographic and clinical characteristics.

RESULTS:

Among 540 patients screened with ICH, after removing those with exclusion criteria, 218 MSU patients were compared with 192 EMS patients. Cohorts had similar baseline demographics, majority male (53.7% MSU versus 49.5% EMS), mean age 67±14 and 68±16, respectively. MSUs reduced time to diagnosis by 28% (β=0.72 [95% CI, 0.62–0.82]; P<0.001). Antihypertensives were administered to 78% of MSU patients, whereas not routinely given to EMS-transported patients until emergency department arrival. This facilitated a time reduction of 54% in the administration time of antihypertensive medications in MSU compared with EMS transported patients (β, 0.46 [95% CI, 0.36–0.59]; P<0.001). With 87% of MSU patients achieving blood pressure goal within 1 hour from last known well, compared with 60% in EMS (P<0.001).

CONCLUSIONS:

MSUs provide faster diagnosis and medical treatment for patients with acute ICH than patients transported by conventional EMS.

Graphical Abstract

Tomato-soy juice lowers inflammation in adults with obesity, suggests study

 

Ask your competent? doctor for specifics if this would reduce inflammation and help recovery in stroke survivors1! You better not get 'the deer in the headlights look'!    

Tomato-soy juice lowers inflammation in adults with obesity, suggests study

SuperAgers shock scientists: How some people over 80 keep brains decades younger

 My social connections are extensive and physical activity is pretty good even with my doctor DOING NOTHING TO CURE SPASTICITY. I'd have to say my resilience is quite high!

Why my stroke was the best thing to ever happen to me 

The latest here:

SuperAgers shock scientists: How some people over 80 keep brains decades younger

In a world where aging is often linked to memory loss and cognitive slowdown, a rare group of individuals is rewriting the rules. Known as “super-agers,” these adults in their 80s and beyond maintain brain performance comparable to people 20 to 30 years younger, according to insights highlighted by The Telegraph and leading neuroscience research.

     

These individuals are not just aging well—they are aging exceptionally. SuperAgers show memory, focus, and mental sharpness that rival much younger adults, challenging the long-held belief that cognitive decline is inevitable.

What makes a brain stay young?

Scientists studying super-agers have found striking biological differences. Their brains tend to resist the typical shrinkage seen with age, particularly in regions responsible for memory and decision-making. In some cases, their cortical thickness resembles that of people decades younger.

Even more surprising, these individuals often have larger brain volumes in key areas linked to memory and movement, and their brains shrink at a much slower rate over time.

But it’s not just about biology—lifestyle plays a powerful role. Research suggests that super-agers maintain strong social connections, which may protect against cognitive decline and even reduce the risk of dementia.

The habits that may unlock a younger brain

One of the most consistent factors is physical activity. Regular exercise—especially a mix of aerobic and strength training—has been strongly linked to better brain health and slower aging.

Diet also matters. Super-agers often follow eating patterns rich in fruits, vegetables, whole grains, and fish, while limiting processed foods and red meat—habits associated with long-term cognitive protection.

Mental engagement is another key pillar. Lifelong learning, curiosity, and challenging the brain through new activities appear to help maintain neural efficiency well into old age.

Equally important is emotional resilience. Many super-agers display positive attitudes and lower stress levels, which may help protect the brain from inflammation and long-term damage.

Finally, strong relationships stand out as a defining trait. Studies show that people who stay socially active tend to preserve cognitive function longer, reinforcing the idea that connection—not just physical health—plays a critical role in brain longevity.

In the end, super-aging isn’t just about luck or genetics—it’s a powerful reminder that daily habits, movement, mindset, and social life can dramatically influence how our brains age

Migraine with aura linked to greater risk for ischemic stroke in older adults

We've known of this migraine  to stroke link for years. The research needed is; 'What treatment of migraines will prevent stroke?' Why hasn't your incompetent? doctor DONE ANYTHING in the past decade to solve  this?

Laziness? Incompetence? Or just don't care? NO leadership? NO strategy? Not my job? Not my Problem!

• Migraine with aura (13 posts to March 2016)

 DAMN IT ALL, SOLVE THE PROPER QUESTION!

Migraine with aura linked to greater risk for ischemic stroke in older adults

Key takeaways:

• Men aged younger than 72 years with migraine also saw an increased risk for this outcome.
• Targeted stroke screening may be recommended for this group if the findings are confirmed, researchers said.

Migraine with aura was associated with an increased risk for incident ischemic stroke in middle-aged adults, with no difference among Black and white patients, according to a study published in Neurology Open Access.

Perspective from Gretchen E. Tietjen, MD

Lead study author Adam S. Sprouse Blum, MD, PhD, clinical instructor at the Larner College of Medicine at the University of Vermont, and colleagues further found that any migraine with or without aura was linked to a greater risk for ischemic stroke in men aged younger than 72 years, which was not found in women or older men. The study authors called this finding “contrary to expectations.”

Risks for ischemic stroke increased by 73% for adults with migraine with aura. Image: Adobe Stock

“Previous research has shown that migraine with aura is linked to an increased risk of stroke in younger people but less is known about people 45 years old and older,” Sprouse Blum said in a press release related to the study. “Our study found that similar to younger people, migraine with aura was associated with an increased risk of ischemic stroke in middle-aged and older adults.”

Sprouse Blum and colleagues culled data from the REasons for Geographic and Racial Differences in Stroke cohort to include 11,381 adults aged at least 45 years (mean age, 72.1 years; 55.2% women; 34.8% Black) in their study. At baseline, participants had not yet had a stroke and were asked about migraine incidence.

During a mean follow-up of 6.4 years, 44 of the 1,130 participants (3.9%) who experienced migraine also experienced ischemic stroke; of the 10,251 participants without migraine, 351 (3.4%) experienced the same. Further, of the 491 adults who reported migraine with aura, 23 (4.7%) reported ischemic stroke. Fewer individuals with migraine without aura (21 of 639; 3.3%) reported the same.

The authors reported the incidence of stroke, calculated per 1,000 person-years, to be 6 in those with migraine — including 7.2 for migraine with aura and 5.1 for migraine without aura — and 5.4 in those without migraine.

The overall risk for ischemic stroke in adults with migraine was not significant in fully adjusted models (HR = 1.35; 95% CI, 0.98-1.87), Sprouse Blum and colleagues wrote. While no association for ischemic stroke was found for those with migraine without aura, the study showed a 73% increased risk among adults who experienced migraine with aura (HR = 1.73; 95% CI, 1.12-2.65).

After stratifying by sex and age, the researchers discovered men aged younger than 72 years with migraine had a 3.5 times increased risk for ischemic stroke (HR = 3.67; 95% CI, 1.96-6.88), regardless of whether they had aura. This finding was not seen in women or in men aged 72 years and older.

The study did not uncover any migraine-by-race interaction.

“Our result that middle-aged and older male participants under age 72 had a much higher risk of stroke was unexpected since previous research in young people has shown that stroke disproportionately affects female individuals,” Sprouse Blum said in the press release.

Future studies are needed to further understand and confirm these findings, he added.

“Should the findings be confirmed, it may be necessary to provide targeted stroke prevention counseling for individuals in this age group,” Sprouse Blum said.

Dopamine Cell Replacement Therapy: A New Frontier in Parkinson Disease Treatment

 Ask your competent? doctor if you should be getting this NOW, as a preventative to your Parkinsons' risk post stroke!

Parkinson’s Disease May Have Link to Stroke March 2017 

The latest here:

Dopamine Cell Replacement Therapy: A New Frontier in Parkinson Disease Treatment

Dopaminergic cell replacement therapy is re-emerging as an investigational strategy for Parkinson disease (PD), supported by a growing number of early-phase clinical trials reporting favorable preliminary safety findings and early motor improvements.1

Evolution of Dopamine Cell Replacement in PD

Early efforts to replace dopaminergic neurons in PD began in the 1980s, but were limited by several challenges.1

“Initial human fetal ventral mesencephalon cell transplantation showed some encouraging results with graft survival and striatal dopamine synthesis,” said Jacob Yomtoob, MD, a movement disorders fellow at Northwestern Feinberg School of Medicine in Chicago, Illinois, and co-author of a 2026 review describing cell therapies and other advanced therapeutics in PD.2

 

When [pluripotent stem cell] technology became accessible, it was almost a no-brainer to develop strategies to derive dopaminergic neurons in the lab with a plan to eventually implant them in the brain.

“However, concerns arose about variable efficacy and graft-induced dyskinesias, and there were also significant supply concerns regarding sourcing fetal stem cells,” Dr Yomtoob continued.

More recently, the open-label TransEuro trial failed to show improvement in the primary outcome – the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Part III OFF score – at 36 months among patients with PD who were treated with human fetal ventral mesencephalic transplantation.3

Those results “largely confirmed the limitations and highlighted the need for alternative pluripotent stem cell sources informed by decades of laboratory studies and in-human trials,” Dr Yomtoob noted.

Together, these limitations have driven a shift toward stem cell-based strategies as a more scalable and standardized approach to dopaminergic replacement.

With advances in cell technology, it is now feasible to generate dopaminergic progenitor cells from sources such as human embryonic stem cells (hESCs), induced pluripotent stem cells (iPSCs), and parthenogenetic stem cells (hpSCs), Dr Yomtoob explained.2

“When [pluripotent stem cell] technology became accessible, it was almost a no-brainer to develop strategies to derive dopaminergic neurons in the lab with a plan to eventually implant them in the brain,” said Viviane Tabar, MD, chair of the department of neurosurgery and the Theresa Feng Chair in Neurosurgical Oncology at Memorial Sloan Kettering Cancer Center in New York, New York.

Dr Tabar cited multiple advantages of pluripotent stem cells (PSCs) compared with fetal stem cells. “They can be expanded on a large scale, and they can be directed to differentiate into very specific neuron types,” she said.1 “Importantly, it was possible to direct differentiation of PSC into authentic midbrain neurons with no serotonergic neuron contamination.”

Serotonergic neurons may have been the cause of dyskinesia in those earlier trials of fetal tissue grafts in PD, Dr Tabar noted.

Among other benefits, PSC-derived products “can be subjected to rigorous quality assurance testing to make sure they have the correct phenotype and are devoid of unwanted contaminants,” Dr Tabar added.1

Building on this preclinical and translational rationale, several early-phase clinical trials have now begun evaluating PSC–derived dopaminergic progenitors in patients with PD.

Recent Early-Phase Trials

In an open-label phase 1 clinical trial (ClinicalTrials.gov Identifier: NCT04802733) published in Nature in May 2025, Dr Tabar and colleagues assessed the safety and tolerability of bilateral putaminal transplantation of a cryopreserved, off-the-shelf hESC-derived dopaminergic neuron progenitor cell product (bemdaneprocel) in 12 patients with PD. Participants were sequentially enrolled in low-dose and high-dose cohorts.4

The trial met its primary endpoints of safety and tolerability at 12 months, and no cases of graft-induced dyskinesia were observed. In addition, no adverse events (AEs) related to the cell product were reported.

Dr Tabar noted that, at 18 months, the data showed continued safety and “no serious adverse events, including no dyskinesias and no tumor formation.”

Among the trial’s secondary endpoints, the MDS-UPDRS Part III OFF scores demonstrated a mean improvement of 8.6 points in the low-dose cohort and 23.0 points in the high-dose cohort. This change is “consistent with a moderate and large ‘clinically important difference’ in motor score,” the authors wrote.4

Additional clinical evidence is emerging from parallel phase 1 and 2 studies using alternative pluripotent stem cell-derived products and manufacturing approaches.

In an open-label dose-escalation phase 1/2a trial (ClinicalTrials.gov Identifier: NCT05887466) published in Cell in December 2025, investigators in Korea evaluated the safety and exploratory efficacy of bilateral putaminal transplantation of freshly cultured hESC-derived dopaminergic progenitors (A9 subtype) among 12 patients with PD. This trial also included a low-dose and a high-dose cohort.5

The study met its primary endpoints at 12 months, with no observed dose-limiting toxicities or graft-related AEs. Exploratory outcomes showed greater MDS-UPDRS Part III OFF score improvements in the high-dose group compared with the low-dose group (15.5 vs 12.7), along with improvements in activities of daily living, motor function, and quality of life.5

Further, a phase 1/2 trial in Japan evaluated bilateral putaminal transplantation of freshly cultured iPSC-derived dopaminergic progenitor cells in 7 patients with PD. The study reported no serious adverse events or graft overgrowth, with mean improvements of 9.5 points in MDS-UPDRS Part III OFF scores and 4.3 points in ON scores.6

Currently, a phase 1 multisite, open-label trial (ClinicalTrials.gov Identifier: NCT06687837)is evaluating autologous iPSC-derived dopaminergic progenitor cells in 12 patients with PD in the United States.7 Xenos Mason, MD, a co-principal investigator on the study and neurologist at Keck Medicine at the University of Southern California in Los Angeles, explained that his team is “conducting studies using neuroimaging and wearable sensors to understand, for example, how stem cells integrate into brain circuits.” Dr Mason added that these methods may elucidate “how the presence of these cells and the dopamine that they produce modifies the intrinsic neurophysiology and the pathophysiology of different forms of [PD].”

Future Directions

As early clinical data continue to accumulate, attention is now shifting toward larger confirmatory trials and longer-term outcome assessment.

The future trajectory of dopamine cell replacement therapy in PD will become more defined in the coming years as larger trials continue to test this approach, according to Dr Tabar.

In addition to ongoing early-phase studies, a phase 3 randomized sham surgery-controlled trial (ClinicalTrials.gov Identifier: NCT06944522) of bemdaneprocel is being conducted at Memorial Sloan Kettering Cancer Center and other sites.

“With more patients receiving the treatment, we expect to learn a lot more about the profile of those who benefit the most, so the indications will become more refined with growing input from patients and their neurologists,” Dr Tabar stated.

While the optimal timing for dopamine cell replacement therapy in the course of PD remains to be determined, Dr Mason suggested some possibilities: “If we think of stem cells as analogous to other procedural therapies for PD, it may be best to use them when medications start to lose efficacy, which tends to occur 3 to 10 years into the course of the disease.”

“However, it may be that stem cells offer a very safe and durable symptomatic improvement, in which case it may be most appropriate to offer the therapy earlier – perhaps soon after diagnostic confirmation,” Dr Mason continued.

According to Dr Yomtoob, dopamine cell replacement therapies in PD will initially be compared with deep brain stimulation (DBS) and magnetic resonance imaging-guided focused ultrasound. “Time will tell if cell therapies have proven benefits over DBS – such as potential for slowing or delaying disease progression and no need for an implanted device or battery replacement – that overcome downsides such as the need for immunosuppression with most dopamine cell therapies, a lack of adjustability over time, and the risk [for] graft-induced side effects.”

Along with long-term safety and efficacy and identification of the optimal patient population, additional questions to be resolved in ongoing research include the optimal dopaminergic progenitor cell source, the need for immunosuppression, and the role of these therapies in the PD treatment landscape, Dr Yomtoob said.

Dr Tabar and other scientists are continuing to explore ideas regarding future versions of cell products, including “development of a better specified dopaminergic neuron subtype, methods to improve graft survival, variations on where exactly in the brain the cells should be grafted, the design of better devices for delivery of the cells, and the possibility of combining cell therapy with novel small molecules or other approaches such as genetically modified cells that impact disease progression or are more resistant to the disease,” she explained.

“Importantly, the success of cell therapy in PD will open the door for similar strategies for other CNS disorders,” Dr Tabar said.

Beet Juice May Lower Blood Pressure in Older Adults Within Two Weeks: Study

 

Your competent? doctor started prescribing this 9 years ago to keep your brain young, right? NO? SO, INCOMPETENCE REIGNED!

This Natural Juice Helps Keep Your Brain Young - Beetroot juice April 2017

I actually found beet juice once and tried it, never again. Even diluting it 9 to 1 with cranberry juice it was undrinkable. 

Beet Juice May Lower Blood Pressure in Older Adults Within Two Weeks: Study

Promising Tool to Predict Poststroke Cognitive Impairment

 WHAT FUCKING STUPIDITY; PREDICTION NOT RECOVERY OR PREVENTION! You're all fired for incompetence! I'd have to say you don't even have two neurons to rub together for a spark of intelligence!

Promising Tool to Predict Poststroke Cognitive Impairment

• Madeline Russell, MD, @maddyrussell16

Ferreira J, Pereira G, Alves F, Fonseca L, Moreira G, Azevedo E, Castro P. Microemboli Detection in Acute Ischemic Stroke Could Be an Early Marker of Poor Cognitive Outcome. Stroke. 2026;57:116–124.

Can transcranial Doppler imaging help predict cognitive impairment after stroke? In posing this question, this study sheds light on two growing areas of interest in the field: the use of transcranial Doppler imaging (TCD) and the burden of cognitive impairment in stroke survivors.

Over recent years, there has been increasing use for TCD in the setting of ischemic stroke. In addition to providing real-time information on vessel hemodynamics that cannot be captured on CT or MR angiography, TCDs can also be used to detect microemboli. Microembolic signals have been shown to correlate with stroke recurrence and, more recently, to correlate with cognitive impairment after carotid intervention.

In this study, the study authors theorize that patients with microemboli signals (MES) are more likely to have ischemic events and the eventual development of cognitive impairment. In short, they ask: Can we use TCD findings of microemboli to predict cognitive outcomes after stroke?

The study was conducted at Centro Hospitalar Universitario de Sao Joao in Portugal and was prospective in design. Patients were included if they had acute ischemic stroke, TCDs could be performed within 72 hours, and prestroke mRS was <4. Patients were excluded if they had conditions that would confound TCD findings or cognitive assessment, including severe aphasia, large infarct size, pre-existing cognitive impairment.

Microemboli detection portion of TCDs was performed for a total of 60 minutes per patient, with 30 minutes each for the anterior circulation (bilateral M1 segments) and posterior circulation (bilateral P2 segments). Presence of MES was defined as at least one positive signal, as analyzed by single experience and blinded reader.

The Bare Minimum You Need to Do to Add a Year to Your Life

  Is your doctor competent enough to get the dietician to incorporate these into the diet protocol at the hospital and your take home diet protocol ? NO? So, your doctor failed at that task! What are YOU going to do about that incompetence? Let it pass? Or pay it forward and get someone competent in the hospital for the next stroke survivor?

Did your doctor also fail at getting you recovered enough to do these exercise amounts?

The Bare Minimum You Need to Do to Add a Year to Your Life

Sleeping, eating, and exercise are crucial to health — and improvements in any of those categories can have big impacts. Now we’re learning that minimal changes to all three can improve health better than focusing on just one area alone. 

That’s the takeaway from new work from Australian researchers that suggests strong synergistic effects. The research is among the first to calculate the effects of lifestyle changes in combination. Findings suggest that adding just 5 minutes of sleep, 2 minutes of moderate activity, and half a serving of vegetables a day can add a full year to your life. 

Emmanuel Stamatakis, PhD

“The central clinical message is that modest combined changes across three behaviors may matter more than trying to overhaul one behavior in isolation,” said Emmanuel Stamatakis, PhD, a professor of physical activity and population health at the University of Sydney and Monash University in Australia.

In 2025, Stamatakis gained notice with a Nature Communications paper that showed each dose of 60 seconds of daily vigorous exercise could add years to lifespan and reduce the risk for cardiometabolic disease and cancer.

Article Key Points

Minimal lifestyle changes, like adding 5 minutes of sleep, 2 minutes of moderate activity, and half a serving of vegetables daily, can extend life by a year, highlighting the power of small, combined health improvements.

Now, drawing from UK Biobank data, his team’s latest findings show a synergistic effect that “argues against an all-or-nothing approach,” Stamatakis said. “If a patient is struggling to make a large change in one area, it may still be worthwhile to pursue smaller gains across several domains at once.”

The Bare Minimum for Longer Life 

The researchers started from a low baseline, creating a composite score for diet, physical activity, and sleep for study participants in the fifth percentile. These people slept about 5.5 hours a night, logged 7.3 minutes of daily moderate activity, and received a diet quality score of 36 out of 100. From there, the researchers set out to find the bare minimum improvements needed to improve lifespan and healthspan.

Here are some conclusions, from the paper published in eClinicalMedicine:

• The minimum: People who added 5 minutes of sleep, 2 minutes of at least moderate activity, and a small diet change such as a half serving of vegetables daily lived 1 year longer than those with the lowest baseline.
• The optimum: Getting 7.2-8 hours of sleep, 43 minutes of moderate activity, and a high-quality diet (score, 57.5-72.5 out of 100) was linked to more than 9 years of additional healthspan and lifespan.
• The synergy: The math shows that these changes multiply each other’s powers. For example, if you rely on sleep alone to add a year to your life, you need an extra 25 minutes a night. But if you combine it with 2 minutes of activity and half a serving of veggies, you need only 5 minutes of additional sleep to get that same extra year.

“What stood out most was how small the estimated combined changes were for a meaningful signal,” Stamatakis said. “We are used to lifestyle advice sounding large, difficult, and sometimes discouraging. Seeing that a few extra minutes of sleep, a couple of minutes of moderate-to-vigorous activity, and a modest diet improvement were associated with an extra year of lifespan was striking.” 

“Equally striking was that the combination mattered so much,” he said. “Scientifically, that reinforces the idea that everyday behaviors interact in the real world, and practically it suggests a more hopeful, less overwhelming message for patients and clinicians.”

The researchers published a separate analysis in the European Journal of Preventive Cardiology that showed similarly small synergistic changes in sleep, activity, and diet lowered the risk for major cardiovascular events.

Call It ‘Progress Over Perfection’ 

That mindset, plus the flexibility of making several small changes, can be important, said Meagan L. Grega, MD, a lifestyle and family medicine physician in Easton, Pennsylvania, and chief medical officer of the Kellyn Foundation, a healthy neighborhood nonprofit initiative that she co-founded. She serves on the governing board of the American Board of Lifestyle Medicine and wasn’t involved in the study.

Meagan L. Grega, MD

Increased moderate-to-vigorous physical activity, is the strongest driver of improvement in lifespan and healthspan, she said, noting dramatic lifespan gains for each 5 minutes daily. Adding improvements in sleep and nutrition could achieve similar benefits with lower amounts of moderate-to-vigorous physical activity — “a more flexible and attainable path for many patients.”

To coach your patients toward small changes, start by asking, “What matters most to you?” Grega suggests. It could be strength and vitality to stay active with the family, or protecting cognitive health. Choosing the behavior gives the patient autonomy and helps them access their internal motivation. 

From there, examine barriers and strategies, Grega said. Improving sleep might mean “creating a consistent wind-down routine or setting a reminder to transition toward bedtime,” she said. “Reviewing a typical day together can uncover opportunities for brief ‘exercise snacks,’ or short bursts of movement woven into existing routines.”

For diet, take a cue from the recent study and suggest adding half a serving of vegetables a day. That’s about one medium carrot, half a bell pepper, or 4 ounces of vegetable juice. 

Pohang Delivers World-Class Stroke Care, Not Seoul

 Any hospital that touts 'care' instead of publishing actual recovery statistics, IS A FAILED HOSPITAL, DON'T GO THERE!

Pohang Delivers World-Class Stroke Care, Not Seoul

Join us FREE for a live webinar focused on neuroplasticity, motor learning, and functional recovery June 15th at 8 pm EST Register Here In this free live webinar, you’ll learn how to intentionally drive brain reorganization through task specific, evidence-based interventions that improve movement, engagement, and long term outcomes across neurologic populations. Tapping Neuroplasticity to Enhance Neurological Recovery Monday June 15th 8 pm - 9 pm EST Save Your Seat For FREE Register today and start transforming the way you approach neurological rehab! CUSTOMER SERVICE: Mon-Fri, 7AM-6PM Central Phone: (800) 433-9570 | Fax: (615) 376-8233 | Email Us | FAQs FOLLOW US: Facebook Instagram LinkedIn YouTube © Summit Professional Education | 501 Union St Ste 545 PMB 626120, Nashville, TN 37219-1876 Unsubscribe | Manage Preferences

 Completely useless; they know ABSOLUTELY NOTHING THAT WILL GUARANTEE NEUROPLASTICITY!

You haven't identified the EXACT signals between neurons that tells one neuron to drop their use and take on a neighboring neuron's use! That could then make neuroplasticity repeatable on demand.  Until that occurs ALL OF THIS SUPPOSED NEUROPLASTICITY RESEARCH IS ALMOST COMPLETELY FUCKING USELESS! 

• Join us FREE for a live webinar focused on neuroplasticity, motor learning, and functional recovery June 15th at 8 pm EST Register Here In this free live webinar, you’ll learn how to intentionally drive brain reorganization through task specific, evidence-based interventions that improve movement, engagement, and long term outcomes across neurologic populations.    Tapping Neuroplasticity to Enhance Neurological Recovery Monday June 15th 8 pm - 9 pm EST Save Your Seat For FREE Register today and start transforming the way you approach neurological rehab! CUSTOMER SERVICE: Mon-Fri, 7AM-6PM Central  Phone: (800) 433-9570 | Fax: (615) 376-8233 | Email Us  | FAQs   FOLLOW US: © Summit Professional Education | 501 Union St Ste 545 PMB 626120, Nashville, TN 37219-1876 Unsubscribe | Manage Preferences