Deans' stroke musings
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 32,740 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Monday, April 13, 2026
Budget Impact Analysis of Kickstart Exoskeletal Technology for Stroke Rehabilitation within the Ontario Hospital System
Study reveals brain mechanisms behind post-stroke urinary incontinence
You as a competent? researcher will immediately contact stroke leadership to get research going that prevents this problem, right! OH NO, you aren't competent and there is NO leadership anywhere in stroke! Nothing will occur!
But your doctors' solution will obviously be catheterization; hope you like carrying a bag of urine around. Maybe dumping it on your doctor might incent them to solve the problem!
Lets check how long your doctor has been ignoring the problem!
- 17% incontinence
(2 posts to September 2022)
- Incontinence
(3 posts to April 2015)
Study reveals brain mechanisms behind post-stroke urinary incontinence
A new USC-led study using functional magnetic resonance imaging (fMRI) reveals the neural mechanisms that contribute to urinary incontinence, a common condition affecting stroke survivors that has a significant impact on their quality of life.
The research, just published in Stroke, was conducted by a multidisciplinary team of urologists, neurosurgeons, and imaging experts from the Keck School of Medicine of USC, Keck Medicine of USC, the Rancho Los Amigos National Rehabilitation Center, and the Shirley Ryan Ability Lab. The team discovered significant differences in brain activity during voluntary versus involuntary bladder contractions, presenting potential pathways for targeted therapies.
Urinary incontinence affects up to 79% of patients in the immediate aftermath and persists in nearly 40% of survivors one year later. It typically arises from uncontrolled bladder contractions and involuntary urine expulsion, leaving patients with debilitating symptoms such as urinary urgency, frequency, and leakage. Although common, it is often undertreated. This condition also predicts poorer long-term outcomes, including higher mortality rates and increased disability.
The brain plays a crucial role in regulating the bladder, allowing people to sense bladder fullness and giving them the ability to delay urination until it is socially appropriate or initiate it at will. In contrast, stroke survivors often struggle to suppress unwanted bladder contractions and may even lose bladder sensation and awareness entirely. Since a stroke impacts the brain, it disrupts the normal pathways that govern bladder control. Nevertheless, the precise neurological foundations of this dysfunction have remained poorly understood until recently."
Evgeniy Kreydin, MD, adjunct assistant professor of clinical urology and lead author of the study
This research played a key role in Kreydin receiving the McGuire-Zimskind Award from the Society of Urodynamics, Female Pelvic Medicine, and Urogenital Reconstruction (SUFU). The award honors early-career professionals within ten years of completing residency or fellowship who have made significant contributions to the field through basic and clinical research. The study utilized an innovative method of repeated bladder filling and voiding while participants were inside the MRI, during which their brain function was measured.
"In contrast to previous studies where participants using a catheter entered the scanner with a full bladder and voided on command, our study enabled us to observe filling and voiding repeatedly. The simultaneous recording of bladder pressure allowed us to identify both voluntary and involuntary bladder emptying. This allowed us to detect differences in brain activity during involuntary emptying for the first time," said Kay Jann, PhD, of the USC Mark and Mary Stevens Neuroimaging and Informatics Institute at the Keck School of Medicine. Jann develops analytical tools and clinical translations of functional MRI technology and served as the imaging expert for the study.
During voluntary bladder emptying, when participants consciously decided when to empty the bladder, both healthy individuals and stroke survivors showed significant activation in brain regions associated with sensorimotor control and executive decision-making. In contrast, involuntary or incontinent bladder emptying in stroke survivors was marked by minimal cortical activation, suggesting a failure to engage key brain networks necessary for urinary control.
We recommend
- Efficacy and safety of ginger-salt-indirect moxibustion for urge urinary incontinence after stroke: protocol for a pilot multicentre randomised controlled trialLinpeng Wang, Li‐Chen Wang, Guang‐Xia Shi, et al., BMJ Open, 2014
- Bladder rehabilitation in stroke survivors: why don’t nurses do it?lisakidd, EB Nursing blog, 2019
- Carers living with stroke survivors who were incontinent had minimal social interaction and felt socially isolatedFrancine Cheater, Evid Based Nurs, 2008
- Rare case of extranodal Rosai-Dorfman disease presenting as a middle cranial fossa tumourJennifer Yang, BMJ Case Reports, 2021
Event guide: 3rd IMPACCT Real World Evidence Summit Europe eBook Real-world data is about turning it into evidence that actually shapes decisions across regulatory, payer, and clinical settings.Download the latest editionIn both healthy individuals and stroke survivors, bladder filling before voluntary urination triggered activity in a collection of brain regions known as the salience network. These brain regions work together to evaluate the importance of internal or external stimuli and coordinate the brain's response to those stimuli. However, during bladder filling that preceded involuntary urination, this network remained inactive for stroke survivors with incontinence. These findings suggest the inability to engage the salience network may be a core mechanism underlying post-stroke urinary incontinence.
These findings open doors for novel interventions aimed at restoring bladder control in stroke patients. Potential therapeutic approaches could include:(Is your doctor and hospital competent enough to ensure this further research occurs? How many times will you need to dump that bag of urine on their heads before they follow thru?)
- Using non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) or direct current stimulation (tDCS), to target the salience network
- Developing medications that enhance neural activation in critical continence control regions
- Cognitive training and biofeedback therapies designed to improve bladder awareness and voluntary control
While the study represents a significant advancement in understanding post-stroke incontinence, the researchers emphasize the need for further investigation. Future studies could explore how different types of strokes affect urinary control and whether early intervention targeting the salience network might help prevent chronic incontinence in stroke survivors.
Charles Liu, PhD, MD, director of the USC Neurorestoration Center, senior author of the study, and coordinator of all the collaborators, is hopeful for further discovery as this important research is built upon. "The neurological basis of urination is still poorly understood, and additional research will be crucial for the neurorestoration of the urinary and reproductive systems," said Liu, who is also a professor of clinical neurological surgery, surgery, psychiatry and the behavioral sciences, and biomedical engineering at the Keck School of Medicine. "This work not only deepens our understanding of a common post-stroke complication but also provides hope for a better quality of life for millions of stroke survivors globally."
This study was funded by a grant from the Urology Care Foundation to Evgeniy Kreydin. The authors include Evgeniy I. Kreydin, MD, Aidin Abedi, MD, Luis Morales, MD, Stefania Montero, MD, Priya Kohli, BS, Nhi Ha, BS, David Chapman, MD, Armita Abedi, MD, David Ginsberg, MD, Kay Jann, PhD, Richard L. Harvey, MD, and Charles Y. Liu, MD, PhD.
11 million views of this blog
I must still be interesting to some people. I have never received
any direct communications from any stroke medical 'professionals'. Are
they scared to talk to me?
First million took from Aug. 2010 to Sept. 2014
Second million from Sept. 2014 to May 2016
Third million from May 2016 to March 2017
Fourth million from March 2017 to November 2018
Fifth million from November 2018 to September 2021
Sixth million from September 2021 to June 2024
Seventh million was from June 2024 to January 2025.
Eigth million was from January 2025 to June 2025
Ninth million was from June 2025 to September 2025;
Tenth million was from September 2025 to January 2026
Eleventh million was from January 2026 to April 2026
The first post was:
What my doctor should have told me about stroke recovery
Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about!
Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!
Coughing with a spastic arm is not good
I've had a cold the last couple of days, runny nose and lots of coughing, If I cover my mouth with my right arm the left arm flies across my lap sweeping the laptop or book to the floor. So, the response has become; grab the left hand with the right to stop the upcoming destruction. And since I live alone I don't have to worry about spreading my germs to others.
My therapists and doctors completely failed at informing me of the consequences of having spasticity. Probably because they believed in the stupid and incorrect opinions of Dr. William M. Landau.
Of course the infamous Dr. William M. Landau thinks spasticity is not worth treating.
Do you believe in the do nothingism of Dr. William M. Landau on spasticity?
His statement from here:
Spasticity After Stroke: Why Bother? Aug. 2004
Wonder if he will be singing the same tune after he becomes the 1 in 4 per WHO that has a stroke, will he be satisfied with not getting recovered?
What 20 Years of Finnish Research Says About Sauna and Living Longer by Super Age
Well shit, your competent? doctor knew all about sauna benefits and made damn sure you had some immediately post stroke! Oh NO, nothing happened because your doctor is so fucking incompetent!
And your doctor required cold showers in the hospital to get those beneficial cold shock proteins, right!
- cold shock proteins
(7 posts to October 2023)
- cold shower
(11 post to January 2017)
I just bought a personal sauna, didn't get the corresponding ice chiller bucket because a friend suggested that getting out of the bucket would be extremely difficult for me. He suggested I just get into a cold shower, and that's what I'll do.
- heat shock proteins
(6 posts to April 2013)
- sauna
(16 posts to January 2015)
What 20 Years of Finnish Research Says About Sauna and Living Longer
Sunday, April 12, 2026
Enriched environments improve stroke recovery and reduce brain inflammation
WOW! You really like proving just how out-of-date you are! You don't follow research at all, do you? Are you're still employed in stroke?
Let's check how long you've been absolutely stupid and missed all the intervening research!
This enriched environment was reported for stroke way back in 2011 by Dr. Corbett.
- Environmental Enrichment
(61 posts to December 2013)
Preconditioning with an Enriched Environment Enhances Neuroplasticity and Functional Recovery Following Cerebral Ischemia-Reperfusion Injury
THIS is the reason survivors need to be in charge, no one in the stroke medical world is putting it all together with a way to get to 100% recovery. No one seems to be up-to-date.
The latest here:
Enriched environments improve stroke recovery and reduce brain inflammation
Stroke is one of the leading causes of death worldwide. Its recovery is often challenging as most of the stroke survivors remain chronically disabled, with motor deficits affecting a significant percentage of patients. Stroke recovery continues long after the initial injury stabilization. In the early recovery period, during the first weeks after the insult, the brain enters a prolonged phase of repair and inflammation. This chronic response can strongly influence poststroke recovery and long-term disability.
The poststroke recovery environment plays an important role in the healing process. Recent studies(Not recent at all; quit lying just to make yourself not look stupid!) suggest that environmental enrichment (EE), a recovery setting that combines greater physical activity, sensory stimulation, and social interaction, can improve recovery. However, how the stimulation affects poststroke brain inflammation and white matter pathology is not well-understood.
To address this, a team of researchers, led by Dr. Lluís Camprubí-Ferrer, from the Experimental Neuroinflammation Laboratory, Lund University, Sweden, conducted an animal-based study to understand the effect of EE on poststroke inflammation, microglial response, and myelin integrity. The study was made available online on February 25, 2026, and was published in Volume 4, Issue 1 of the journal Neuroprotection on March 01, 2026.
"EE is known for exerting beneficial effects on neuroplasticity and recovery after stroke. However, a systemic study on understanding the microglial phenotypes during the recovery period after stroke under enriched housing conditions was lacking. Our study addresses this research gap," says Dr. Camprubí-Ferrer.
The researchers induced photothrombotic (PT) stroke, a commonly used experimental model that creates a localized injury in the brain, in male mice and randomized mice into standard environment (SE) or to an EE with more space, social contact, exercise opportunities, and frequently changed objects. The mice were then monitored for sensorimotor recovery over 3 weeks. In addition, they examined the brain for signs of microglial activity and myelin damage.
The behavioral findings clearly highlighted the role of EE in PT stroke recovery. Mice housed in EE performed better on tests of paw placement, foot fault, and limb symmetry, with benefits persisting through 21 days after stroke. When the researchers combined these outcomes into an overall neurological score, the EE group showed stronger recovery.
A guide to advancing biotherapeutic research eBook Welcome to your essential guide to advancing biotherapeutic research.Download the latest editionThe tissue analysis revealed that in SE mice, larger infarcts were closely linked to stronger chronic inflammatory signals. In addition, larger lesions were associated with more myelin debris around the infarct and greater loss of myelin in white matter. In contrast, in EE mice, the usual link between infarct size and chronic inflammatory markers like galectin‐3 was largely absent. The same was true for myelin debris accumulation and white matter myelin loss. The findings suggest that enrichment weakened the tendency for larger lesions to drive stronger long-term inflammation and tissue disruption.
In white matter, higher levels of triggering receptor expressed on myeloid cells 2 (TREM2)-positive microglia were associated with better neurological recovery in EE mice. No other inflammatory or myelin marker showed such a robust relationship with behavior. This highlights TREM2-positive microglia as a potential cellular link between EE and improved functional recovery.
"Our findings suggest that interventions like EE that targets microglial marker suppression and TREM2 potentiation may contribute to post‐stroke white matter repair and improve functional outcomes," concludes Dr. Camprubí-Ferrer.
Camprubí‐Ferrer, L., et al. (2026). Environmental enrichment modulates chronic poststroke inflammation and links white matter TREM2‐positive microglia in recovery in mice. Neuroprotection. DOI: 10.1002/nep3.70028. https://onlinelibrary.wiley.com/doi/10.1002/nep3.70028
The Surprising Mindset That Influences How Fast You Age
Your competent? doctor will then also confirm that this earlier research is totally wrong! Oh NO, your doctor doesn't know about it, does s/he?
My positive outlook is over the top; having fun the rest of my life!
The Surprising Mindset That Influences How Fast You Age
It’s normal to feel frustrated with getting older when you need to go through an intense recovery process after a workout just to feel like a functioning human the next day. But stressing about the impact of aging on your health can actually work against your goal of having a longer health span, according to new research.
The study, which was published in the journal Psychoneuroendocrinology, found a shocking link between the way women view aging and the actual pace at which they age. Ultimately, researchers found that worrying about your health as you get older can impact you on a cellular level.
Sure, there’s a big difference between being a little annoyed that your 5K time isn’t what it used to be and actually stressing about your future health. But psychologists say the findings make a solid case for trying to do what you can to turn a negative mindset around, especially when it comes to your future health. Here’s why.
Fears about health can ultimately worsen your future health.
For the study, researchers analyzed data from 726 women who took part in the Midlife in the United States (MIDUS) study. As part of the research, the participants were asked how much they worried about common fears that tend to surface with aging, including how much they stressed about becoming less attractive with age, having more health issues, and being too old to have children.
The study also collected blood samples to track aging using two epigenetic clocks. One, called the DunedinPACE biological marker, looked at a person’s pace of biological aging while the other, called the GrimAge2, estimated biological damage that built up over time. After crunching the data, the researchers found that women who reported having higher levels of anxiety about getting older also had faster epigenetic aging. (In case you’re not familiar with it, epigenetic aging looks at a person’s biological age based on chemical changes to their DNA.)
When they dove a little deeper, the researchers found that fears about declining health in particular were the most strongly linked with a faster pace of epigenetic aging. However, worries around a decline in attractiveness and fertility weren’t strongly linked with epigenetic aging. The researchers ultimately concluded that “fears about declining health may manifest biologically and contribute to accelerated aging processes.”
What’s going on here?
It’s important to point this out: The study didn’t definitively prove that women who had more anxiety around aging actually aged faster. Instead, it found a link between fears around aging and signs of accelerated aging. “More research is needed to determine whether these concerns directly cause these changes,” Mariana Rodrigues, lead study author and a PhD student in the department of social and behavioral sciences at the NYU School of Global Public Health, tells SELF.
Still, psychologists say it’s not shocking to think that worries about your well-being may lead to worse health. Fears around health can spark a chain reaction that ultimately has an impact on your physical health, Thea Gallagher, PsyD, clinical associate professor at NYU Langone Health and cohost of the Mind in View podcast, tells SELF. “Worry and anxiety causes stress and strain on your body,” she says. “It takes up a lot of mental resources, which then take up physical resources.”
Stressing about your future health can impact your sleep, heart rate, and your nervous system, and all of those can contribute to worse health outcomes, Dr. Gallagher says.
It can also do a number on your heart health, Hillary Ammon, PsyD, a clinical psychologist at the Center for Anxiety and Women’s Emotional Wellness, tells SELF. “The body reacts to anxiety in similar ways to how it reacts to fear,” she says. “When we are experiencing these emotions, the body releases [stress hormones] cortisol and epinephrine, along with neurotransmitters like norepinephrine and glutamate. So if someone is constantly worrying about their physical health, it may put these hormones and neurotransmitters in overdrive.”
This can even cause your blood sugar to fluctuate and fuel chronic inflammation in your body, Dr. Ammon adds. Unfortunately, chronic inflammation is linked to a range of serious health conditions, including autoimmune diseases, heart disease, and cancer. “By chronically worrying about their health, individuals unfortunately create more health problems, leaving them more susceptible to additional health issues,” Dr. Ammon says.
One more thing to consider, per Dr. Ammon: When you have health anxiety, you tend to be hypersensitive to what’s happening with your body. “You may notice minor changes, which in turn, likely makes their anxiety worse,” she says. “It is a cyclical pattern.”
How to navigate health fears around aging
It’s normal and okay to worry sometimes about your health, Dr. Gallagher points out. But the big concern is when you regularly stress about it.
“People worry naturally, but often don't pause to consider whether the worry is helping anything,” Jessica Bodie, PhD, a licensed clinical psychologist at the Center for the Treatment and Study of Anxiety at the University of Pennsylvania, tells SELF. “By not giving the anxious thought as many follow-up behaviors—scanning, Googling—the brain registers the anxious thought as less valid.”
Worrying “keeps out of the present and in the future,” Dr. Gallagher points out. That’s why she recommends doing what you can to focus on what’s in front of you. Are you in generally good health now and doing all you can to stay healthy? Great—focus on that.
“We also have to be really careful that if your friend is diagnosed with cancer, that you feel like it’s happening everywhere and will happen to you,” Dr. Gallagher says. “Sometimes we’re just more attuned to the negative things happening with people’s health versus thinking about how another friend who just ran a marathon is in great health.”
Dr. Gallagher stresses the importance of differentiating your own health status from those of people around you and trying to remind yourself of the things you can and can’t control. And, of course, try not to worry about the potential impact stressing about your health will have on your health—that’s not solving any issues either.
Of course, if you’re struggling with health anxiety and it’s impacting your day-to-day, Dr. Ammon says it’s a good idea to talk to a mental health professional. They can help you navigate your concerns as well as go over strategies to deal with those fears when they pop up.
But Dr. Gallagher also recommends trying to keep something very important in mind when it comes to worries about your future health. “You don’t want to live your life worrying about what could happen,” she says. “It’s either going to happen or not, and worrying won’t change anything.”
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Originally Appeared on Self
Saturday, April 11, 2026
Study Explores Whether Midlife Vitamin D Levels May Protect Against Early Alzheimer's Risk
You'll want to read all these vitamin D posts for warnings and benefits!
- (vitamin D 35 posts to May 2012)
Study Explores Whether Midlife Vitamin D Levels May Protect Against Early Alzheimer's Risk
They talk about early midlife so since I just exited midlife by turning 70 I guess I'm too late.
Motor Learning Principles in Stroke Rehabilitation: A Trial Comparing Task Specific Vs Conventional Therapy
If these motor learning principles and EXACT 100% RECOVERY PROTOCOLS ARE LACKING! Then your fucking job is to create them. YOU COMPLETELY FAILED AT THAT!
Motor Learning Principles in Stroke Rehabilitation: A Trial Comparing Task Specific Vs Conventional Therapy
Abstract:
Multimodal assessment of upper limb rehabilitation in stroke patients based on cross-attention mechanism
What will it take to get thru your thick skulls that 'assessments' do nothing for recovery unless THEY POINT DIRECTLY TO EXACT RECOVERY PROTOCOLS?
This did nothing towards that, so useless!
Multimodal assessment of upper limb rehabilitation in stroke patients based on cross-attention mechanism
Highlights
- •Non-contact 3D motion capture (Azure Kinect) joint angle MAE< 6° vs. NOKOV.
- •Res-Transformer feature extractor: 0.807–0.811 avg. acc (kinematics/EMG).
- •ReT-CA fusion model powers digital system: 89.2% avg. acc for stroke assessment.