Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, May 4, 2026

Nebraska Medicine first in the state to offer breakthrough therapy for stroke

 

Wow, admitting incompetence in how long it took to bring vagus nerve stimulation into their stroke practice. And you haven't fired the board of directors for incompetence yet?

vagus nerve (67 posts to July 2012)

vagus nerve stimulation (1 post to February 2023)

paired vagus nerve stimulation (2 posts to April 2022)

The latest here:

Nebraska Medicine first in the state to offer breakthrough therapy for stroke

Mark Wilson knows firsthand how difficult stroke recovery can be.

Four years ago, he woke up noticing something wasn’t right with his left side. A stroke significantly impacted his arm, hand, leg and foot. Years of rehab work with Nebraska Medicine occupational therapist Stacy Reichmuth followed.

Despite his hard work, like many stroke survivors, Wilson reached a point where progress slowed. Now, as the first patient in Nebraska to receive the Vivistim implant, he’s hoping to push past that plateau.

“I don’t think I would like to be sitting here a year or two from now and not doing it,” Wilson says.

One of his goals is simple but meaningful: return to the golf course.

“I golfed four or five times a week,” he says. “That’s the thing I miss tremendously.” 

Pushing past the plateau

For years, stroke care has focused on one critical window: the moments immediately after a stroke occurs, when rapid treatment can minimize brain damage. But for many patients, recovery has long plateaued once that window closes.

Now, Nebraska Medicine is offering new hope. “This is just the most exciting thing that’s probably happened to stroke rehab in years," says Reichmuth.

As the first health system in Nebraska to provide Vivistim, doctors and therapists are helping stroke survivors regain function sometimes years after their stroke by tapping into the brain’s ability to rewire itself.

“This really is a big deal,” says neurosurgeon Josue Avecillas-Chasin, MD. “Once a stroke is established and a patient is left with deficits, historically, we haven’t had much to offer beyond rehabilitation. This changes that.”

How Vivistim works

Vivistim is an implanted device that functions in tandem with the work being done by occupational therapists such as Reichmuth. It delivers mild stimulation to the vagus nerve, which is a key communication pathway to the brain. This happens when patients perform specific rehabilitation exercises.

The goal: enhance neuroplasticity, or the brain’s ability to form new connections.

“The vagus nerve is like a highway to the brain,” Dr. Avecillas-Chasin says. “About 80% of its fibers go directly there, so it’s a very efficient route to activate the brain during therapy.”

During therapy sessions, clinicians activate the device at key moments as patients perform targeted movements. Over time, this pairing helps reinforce new neural pathways, improving movement and function.

Reichmuth works with Mark during his first session with the device
Reichmuth works with Mark during his first session with the device

Reichmuth describes the effect as “fertilizer for the brain,” helping accelerate recovery when paired with purposeful movement.

The therapy is designed for adults with ischemic stroke (a clot-related stroke), which is the most common type. These patients continue to experience upper limb weakness or loss of function.

One of the most promising aspects: patients don’t need to be newly diagnosed.

“There’s no strict limit on how long ago the stroke occurred,” Dr. Avecillas-Chasin said. “Even patients years out from their stroke may still benefit.”

The device is about the size of a pacemaker and is implanted in the chest, with a lead connected to the vagus nerve in the neck.

Reichmuth activates this clicker when Wilson makes meaningful movements
Reichmuth activates this clicker when Wilson makes meaningful movements

 

The procedure typically takes three to four hours, followed by a short recovery period before therapy begins.

Patients like Mark then complete a structured rehabilitation program, often including multiple sessions per week. The device is activated during exercises, and they can also continue therapy at home using the device.

“The more patients engage in therapy, the more benefit we expect to see,” Dr. Avecillas-Chasin says.

While the technology is still relatively new, early data is encouraging.

Clinical trials suggest patients using the device alongside therapy can see improvements two to three times greater than just therapy alone. And benefits may extend beyond just arm function.

“These improvements aren’t always isolated,” Reichmuth says. “They can affect balance, walking, even mood.”

As awareness grows, Nebraska Medicine expects demand to increase rapidly. In fact, multiple additional patients have already been referred for the therapy since the first procedure.

Reichmuth worked with Mark on his golfing skills during the first sessionReichmuth worked with Mark on his golfing skills during the first session

 

For patients like Wilson, that momentum represents something powerful: renewed possibility. He says his two daughters, one who is an occupational therapist herself, are holding him accountable.

“She asked me all sorts of questions, and she thinks it’s awesome,” Wilson says of his daughter. “Both of them are really strict, and they’ll become, I think, a little bit more watchful over me to make sure I’m doing things right.”

Watch the WOWT story featuring Mark and occupational therapist Stacy Reichmuth: 
First Nebraska Patient Receives New Implant For Stroke Recovery

Who qualifies for the device?

  • Are at least six months post-stroke
  • Are adults (generally 22 or older)
  • Have had an ischemic (clot-related) stroke
  • Continue to have upper extremity impairment
Patients who would like a consultation can call 402.552.2464

Extracorporeal shock wave therapy for post-stroke spasticity: an umbrella review of systematic reviews and meta-analyses

 

But there is no need to treat spasticity, Dr. William M. Landau says so in his uninformed 'expert' opinion.  Survivors would immediately disabuse him of that notion. When comeuppence hits him with his stroke he'll regret his ideas on the matter. 

Unfortunately, you will not be able to because shockwave devices are not sold to the general public because it is unsafe and against the law. Plus, they cost about $50,000.

But lots more research needed.

His statement from here:

Spasticity After Stroke: Why Bother? Aug. 2004 

The latest here:

Extracorporeal shock wave therapy for post-stroke spasticity: an umbrella review of systematic reviews and meta-analyses


  • 1. School of Nursing, Hunan University of Chinese Medicine, Changsha, China

  • 2. Department of Neurology, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China

Abstract

Introduction: 

This umbrella review aims to synthesize and critically evaluate existing systematic reviews and meta-analyses to determine the efficacy of extracorporeal shock wave therapy for post-stroke spasticity, along with the quality and reliability of the evidence.


Methods: 

A comprehensive search of eight databases (up to May 2025) was conducted to identify systematic reviews and meta-analyses evaluating extracorporeal shock wave therapy for post-stroke spasticity. Two scholars independently screened the literature and extracted data. The methodological quality of the included systematic reviews and meta-analyses was appraised using AMSTAR 2, and the certainty of evidence for each outcome was rated using the GRADE approach. Overlap of primary studies across reviews was assessed and visualized using the GROOVE tool.


Results: 

A total of 17 systematic reviews and meta-analyses were included. Among these, 3 were rated as high quality, 2 as moderate quality, 7 as low quality, and 5 as very low quality. Evidence mapping identified 136 nodes, indicating moderate overlap. All included systematic reviews and meta-analyses suggested that extracorporeal shock wave therapy improves

(There is NOTHING TO CURE SPASTICITY! Survivors want cures, not treatments that don't GET THERE!)post-stroke spasticity. Extracorporeal shock wave therapy helps reduce spasticity, improve sensorimotor function, increase active and passive range of motion, and alleviate pain.


Discussion: 

This umbrella review suggests that extracorporeal shock wave therapy can improve

(There is NOTHING TO CURE SPASTICITY! Survivors want cures, not treatments that don't GET THERE!)

post-stroke spasticity symptoms. However, due to the generally low methodological quality of the included systematic reviews and meta-analyses, the existing evidence remains limited and inconclusive. Language restrictions and the predominance of studies from a single country may also limit their generalizability. Further high-quality research is needed to strengthen the evidence base.

Systematic review registration: 

identifier: CRD420251124065.

Psychological resilience and functional recovery after acute ischemic stroke: a prospective cohort study

Resilience in only needed because your stroke medical 'professionals' have completely failed at 100% recovery protocols!

With EXACT 100% RECOVERY PROTOCOLS your survivor will gladly do the millions of reps needed because they are looking forward to recovery!

Psychological resilience and functional recovery after acute ischemic stroke: a prospective cohort study

    • N

      Ning Wang

    • Yaoyao Zhang

      Y

Cerebrovascular Disease Center, The affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

Abstract

Background: 

Psychological resilience has been proposed as a factor that may influence recovery after stroke, yet evidence regarding its independent contribution to functional outcomes remains limited and inconsistent. This study evaluated the association between baseline psychological resilience and longitudinal functional recovery following acute ischemic stroke during structured rehabilitation.


Methods: 

In this prospective cohort study, adult patients with imaging-confirmed acute ischemic stroke were enrolled during hospitalization and followed for 6 months. Psychological resilience was assessed using the 10-item Connor–Davidson Resilience Scale. Functional outcomes were measured using the modified Rankin Scale at 6 months and the Barthel Index at discharge, 3 months, and 6 months. Multivariable ordinal logistic regression was used to examine the association between resilience and functional outcome after adjusting for age, sex, stroke severity, comorbidity burden, rehabilitation exposure, and mood symptoms.


Results: 

A total of 241 patients were included. Functional outcomes improved progressively over time, with the greatest gains observed during the early rehabilitation period. Baseline psychological resilience was associated with demographic and psychological characteristics but was not independently associated with functional recovery after adjustment for clinical factors. Sensitivity analyses using a binary definition of favorable outcome demonstrated an association between baseline stroke severity and recovery.


Conclusion: 

In this prospective cohort of patients undergoing stroke rehabilitation, psychological resilience was not an independent predictor of functional outcome. Recovery was primarily determined by established clinical factors. These findings suggest that resilience may influence adaptation to illness rather than neurological recovery itself.

A narrative review of AI-driven stroke rehabilitation systems through the lens of human motor learning

 I can't tell if this got anywhere closer to getting survivors recovered!

A narrative review of AI-driven stroke rehabilitation systems through the lens of human motor learning


  • 1. School of Computer Science, University of Nottingham, Nottingham, United Kingdom

  • 2. School of Psychology, University of Nottingham, Nottingham, United Kingdom

Abstract

Introduction: 

Stroke represents a leading global cause of disability, often causing motor impairments that diminish quality of life. Neurorehabilitation that leverages human motor learning (HML) theories is crucial for post-stroke recovery. Therapists guide repetitive practice that supports re-learning, and they adjust assistance to individual needs and progress. Robot-assisted rehabilitation has advanced this approach, and recent work shows AI-driven systems can improve adaptability to patient behavior beyond earlier technologies. However, notably few systems aim to explicitly replicate therapist assistance from the perspective that physical assistance is a motor skill in itself.


Methodology: 

This narrative review examines advances in AI-driven stroke rehabilitation, analyzing how systems facilitate HML within patients and how their models approximate HML mechanisms. By breaking down the four core HML processes to their essentials, using Marr's tri-level hypothesis, we compare machine learning models used within rehabilitation systems to the HML processes.


Results: 

Many of the reviewed systems appear to primarily facilitate use-dependent and sensory-prediction error-based learning, with limited facilitation of reinforcement learning or strategy-based learning. Explicit modeling of therapist HML within control frameworks appears relatively rare. Implicitly, many of the reviewed AI systems functionally represent one or two HML processes.


Conclusion: 

Current research often considers HML primarily in patients, whereas therapists' own HML likely underpins the robustness and adaptability of clinical assistance. Interpreting the reviewed rehabilitation systems through this lens highlights opportunities for therapist-inspired multi-process controllers, improved benchmarking with clinical scales, longitudinal retention studies, and AI-driven closed-loop neuromodulation to enhance personalization, adaptability, and outcomes, and to support clinical translation into routine practice.

The Real Predictor Of Longevity Isn't What You'd Expect by mindbodygreen

 I'm not obsessing over longevity, I know I'll get there. Life is fun and I'm enjoying it.

The Real Predictor Of Longevity Isn't What You'd Expect

We tend to think of health as a snapshot: how we're doing right now. Your latest blood pressure reading, your current weight, whether you made it to the gym this week. But what if your health over time matters more than any single moment?

A new analysis from the Framingham Heart Study suggests that decades of habits may leave a lasting mark on how long you live. Researchers tracked participants for nearly three decades1, and the results add to a growing body of research on what it really takes to stay healthy as you age.

About the study

We know that healthy habits lower the risk of heart disease and early death. But most research looks at health at a single point in time, which doesn't capture how habits change (or stay the same) over the years.
Researchers wanted to know whether the accumulation of healthy behaviors across decades, not just a single checkup, relates to long-term disease risk and death.

They followed 3,231 people across multiple exam cycles over roughly 25 years, then tracked health outcomes for a median of 28 years. The average age was 55, and 53% were women.

To measure health, researchers used the American Heart Association's Life's Essential 8 framework, which includes eight key markers: diet, physical activity, smoking status, BMI, blood pressure, cholesterol, and blood sugar. Instead of looking at just one point in time, the team added up each person's scores over the full study period to create a cumulative health score, capturing the total benefit (or burden) of health behaviors sustained over decades.

Decades of healthy habits linked to lower disease & death risk

People with the highest cumulative scores had dramatically lower risk across all outcomes compared to those with the lowest scores.

Specifically, those in the top quarter had:

  • 73% lower risk of cardiovascular disease
  • 84% lower risk of coronary heart disease
  • 77% lower risk of heart failure
  • 55% lower risk of stroke
  • 63% lower risk of death from any cause
People with above-average cumulative scores lived an average of 7.4 years longer without cardiovascular disease and 4.6 years longer overall compared to those below average.
These results held even after accounting for each person's current health score at the final exam. In other words, your health history matters beyond where you stand today.

Improving over time still counts

The researchers also looked at whether people's health scores were going up or down over time.

People whose scores were improving had lower risk of heart disease and death, even after accounting for their overall cumulative score. This means changing your direction can still make a real difference.

However, the data also showed that 55% of people had declining scores over time. Most people's cardiovascular health gets worse with age, but it doesn't have to. It's not about perfection—it's about direction.

How to build better health over time

This research reframes health as something you build over years, not something you achieve in a single moment. Here's how to put that into practice:

Think in years, not days: Small daily movement habits like a morning walk or an extra serving of vegetables add up over time. The goal isn't a perfect week; it's a sustainable path forward.
Choose consistency over intensity: Avoid all-or-nothing cycles. Moderate habits you can keep up for decades beat short bursts of "perfect" behavior followed by burnout.
Focus on what matters most: The Life's Essential 8 framework highlights the big levers: movement, consistent sleep, diet, and metabolic markers like blood pressure, cholesterol, and blood sugar.
Track your direction: If your health is improving over time, that counts, even if you're not where you want to be yet.
Start now: Health debt builds up. The earlier you begin healthy habits, the greater the benefit over time; it becomes harder to reverse course later.

The takeaway

Your cardiovascular health is cumulative: decades of habits shape your risk of heart disease, stroke, and early death. This Framingham analysis shows that consistency over time matters more than any single snapshot. Improving your path still counts, so it's never too late to start.

Want To Improve Balance, Flexibility, & Agility? Study Says To Try This by mindbodygreen

You'll need to have your doctor and hospital initiate this research on stroke subjects. Not doing so IS INCOMPETENCE!

Do you prefer your doctor, hospital and board of director's incompetence NOT KNOWING? OR NOT DOING? Your choice; let them be incompetent or demand action!


Want To Improve Balance, Flexibility, & Agility? Study Says To Try This

If you've ever tried balance exercises and felt wobbly, unstable, or like you might actually fall–you're not alone. Most balance training puts you in precarious positions by design. But what if the best way to improve your standing balance was to lie down?

Researchers in Japan developed a 10-minute exercise routine that significantly improved balance, agility, and flexibility in just two weeks. The best part? The whole workout is on your back, so there are no high-impact movements or risk of falling.

How the study worked

Researchers ran two experiments with 39 healthy young adults total. Participants spent approximately 10 minutes each day doing three types of floor exercises while lying on their backs. After two weeks, researchers measured changes in balance, agility, and flexibility.
The routine included:

Abdominal activation: Participants placed their hands on different areas of their abdomen and practiced contracting those muscles against light finger pressure. This helps wake up the deep core muscles that stabilize your trunk.
A modified bridge: Participants tilted their pelvis backward while keeping their abdomen engaged, then lifted their hips slightly off the floor. This builds the connection between your core and your legs.
Heel slides and toe exercises: Participants extended one leg at a time while keeping the ankle flexed, plus did toe movements (essentially playing rock-paper-scissors with their toes). These train the muscle patterns your body uses during walking and standing.

Why lying down actually works

You might not expect exercises done lying down to improve balance, so let's break down how this works. When you're standing, your body is constantly working against gravity. Your muscles are firing just to keep you upright, which makes it harder to focus on the specific coordination patterns that actually improve balance.

When you're lying down, that gravitational load disappears. Your body is supported by the floor, which allows your nervous system to focus on building better connections between your trunk and lower body without the distraction of trying not to fall over.
The researchers found that improvements came from neural adaptations, not muscle building. Participants didn't get stronger in traditional measures like grip strength or jumping power. Instead, their brains got better at coordinating movement.

Measurable improvements

After two weeks, the exercise group showed significant improvements in several areas:

Static balance: When standing with feet together, participants showed reduced postural sway, meaning they wobbled less.
Agility: In a side-step test measuring how quickly participants could move laterally, the exercise group completed significantly more steps.
Flexibility: Sitting trunk flexion (reaching forward while seated) improved notably.
Movement efficiency: During the agility test, participants moved their heads and trunks with less corrective wobbling, suggesting more stable, efficient movement patterns.
Measures of raw strength and power, like grip strength, standing long jump, and sprint speed, didn't change. This confirms the improvements came from better coordination, not bigger muscles.

Why this matters for fall prevention

One of the most practical applications here is fall prevention. Traditional balance training often requires standing on one leg, using unstable surfaces, or performing movements that carry inherent fall risk. This can be a barrier for older adults or anyone recovering from injury, who often need balance exercises the most..

This routine eliminates that problem entirely. You're already on the ground, so there's nowhere to fall. The exercises are low-impact and can be done at home without equipment.
The researchers note that while this study focused on healthy young adults, the approach may be useful for early-stage rehabilitation and fall prevention programs. The short duration and safe position make it accessible for people who might struggle with traditional balance exercises.

The takeaway

You don't need to stand on a wobble board or balance on one foot to improve your stability. This research suggests that 10 minutes of targeted floor exercises can meaningfully improve balance, agility, and flexibility in just two weeks.

Mirror Therapy in Stroke Patient Rehabilitation: Scoping Review

 Massive incompetence here if you think mirror therapy is emerging!

Mirror Therapy in Stroke Patient Rehabilitation: Scoping Review


The Role of Creatine Supplementation in Post-Stroke Rehabilitation: Promising but Still Unresolved

 Are your doctor and hospital competent? enough to drive research that solves the question? I'm guessing not.

You can read up on creatine yourself:

The Role of Creatine Supplementation in Post-Stroke Rehabilitation: Promising but Still Unresolved

Description

Stroke is a major cause of long-term disability, often leading to functional impairment. Beyond neurological damage, stroke-related sarcopenia from immobility and inflammation worsens recovery outcomes. Creatine, which enhances energy metabolism and shows neuroprotective properties, has been proposed as an adjunct therapy to improve functional rehabilitation after stroke. This systematic review evaluates the safety, efficacy, and potential mechanisms of creatine supplementation in stroke recovery.

MEDLINE, Embase, and CENTRAL databases were systematically searched till October 1, 2025 assessing creatine use in stroke survivors. Eligible designs were randomized or interventional studies assessing muscle mass, strength, mobility, and inflammatory outcomes of creatine supplement for post stroke recovery. Data was extracted and appraised using standardized quality assessment tools, and findings were narratively synthesized due to heterogeneity among studies.

Three studies (n=71) were included from 1,167 studies screened, with a mean follow-up duration of 58 days. Across three studies, creatine supplementation in stroke showed mixed results. The ICaRUS Trial (10 g/day for 7 days) found no improvement in muscle or functional recovery but noted reduced serum progranulin, suggesting anti-inflammatory effects. Butchart et al. reported better walking performance with creatine plus resistance training, while Meulengracht et al. found no functional or endurance benefits with creatine and maltodextrin. Overall, creatine was safe, well tolerated, and showed no adverse effects.

Creatine appears safe and may improve functional recovery, particularly with exercise in post-stroke patients. Limited evidence, by small sample sizes and methodological variability, suggests potential anti-inflammatory and neuroplastic effects. Larger, high-quality randomized controlled trials are needed to define optimal dosing, timing, and therapeutic efficacy in mitigating stroke-related sarcopenia and enhancing recovery outcomes.

Publication Date

5-8-2026

Disciplines

Neurology