Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label N-dimethyltryptamine. Show all posts
Showing posts with label N-dimethyltryptamine. Show all posts

Saturday, February 6, 2021

Stroke victims to be given psychedelic drug DMT in groundbreaking study

An explanation of what DMT is:

While ayahuasca, a hallucinogenic and often purgative tea brewed from leaves of a shrub that grows in South America, contains the psychoactive compound N, N-dimethyltryptamine (DMT), it also packs harmine and tetrahydoharmine, two compounds that form new neurons from stem cells in a petri dish, per IFL Science.

Ayahuasca is used in spiritual practices across different belief systems, and Healthline explains that the plant’s naturally occurring DMT—which can produce powerful hallucinations and visions—works in tandem with another compound that makes it more “bioavailable.” That means it’s absorbed better by the body, with less flushed out as waste afterward. Think about how calcium and vitamin D work together to increase absorption.

Don't worry, this will never get approved in the US

 

 Stroke victims to be given psychedelic drug DMT in groundbreaking study  

Psychedelic drug DMT could help stroke victims recover by rewiring their brains faster, according the first clinical trial of its kind. It is hoped the substance, also known as the ‘the spirit molecule’, could even be given to patients as soon as they’re in the ambulance, minimising the damage and maximising their recovery. Algernon Pharmaceuticals, who set out the plan for their study this week, say participants will be given a microdose, which won’t make them ‘trip’, but will still help the neurons in their brain make new connections. If the trial proves successful and gets regulatory approval, it could open up a whole new world of research for people with multiple sclerosis, Parkinson’s and many other conditions affecting the brain. Among the study’s global luminaries is Professor David Nutt, of Imperial College London’s Centre for Psychedelic Research, which has looked into potential for psilocybin (magic mushrooms) to treat depression. Algernon, based in Vancouver, Canada, are the world’s first company to try using DMT (dimethyltryptamine) for strokes, and if they get promising results, they hope to be fast-tracked by regulators in the US. CEO Christopher Moreau told Metro.co.uk: Since we’re dealing with stroke patients, we will be using the sub-hallucinogenic dose, which in pre-clinical studies has still shown to improve neuroplasticity. ‘It will help the brain heal even though patients aren’t having the psychedelic experience, and we really don’t want that if your patient has just had a stroke.’ DMT occurs in many plants and animals, but Algernon will produce theirs synthetically (Picture: Getty Images) Algernon have been buoyed by a study last year in which blood flow was blocked off for one half of the brain in rats. Rodents who were given DMT recovered motor-function and rebuilt brain cells more efficiently and had fewer lesions on the brain. ‘We’re going to take that information now and move very quickly to test it in humans,’ Mr Moreau said. He explained how there is still ‘very little available’ for stroke victims in the immediate aftermath and that DMT could help fill the void. Part of the problem is that two of the main types of stroke are very different and require different types of treatment. Christopher Moreau, CEO of Algernon Pharmaceuticals, based in Vancouver, Canada Christopher Moreau hopes the study could open a whole new field for people with other illnesses (Picture: Algernon Pharmaceuticals) Ischemic strokes occur due to a blood clot blocking a vessel in the brain and are often treated with blood thinner. But if you did this for someone suffering from a haemorrhagic stroke – caused by bleeding in or around the brain – you could kill them. For this reason patients have to wait for a CT scan, which could take hours, leaving more time for the brain to incur damage. Mr Moreau said: ‘The sooner you can start to treat post-injury the better. DMT may not benefit hemorrhagic, we don’t know, but we’re hoping it won’t cause them any problems because then we don’t have to wait for the CT scan, we can treat in the ambulance.


Read more: https://metro.co.uk/2021/02/04/stroke-victims-to-be-given-psychedelic-drug-dmt-in-groundbreaking-study-14023757/?ito=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

 

Psychedelic drug DMT could help stroke victims recover by rewiring their brains faster, according the first clinical trial of its kind. It is hoped the substance, also known as the ‘the spirit molecule’, could even be given to patients as soon as they’re in the ambulance, minimising the damage and maximising their recovery. Algernon Pharmaceuticals, who set out the plan for their study this week, say participants will be given a microdose, which won’t make them ‘trip’, but will still help the neurons in their brain make new connections. If the trial proves successful and gets regulatory approval, it could open up a whole new world of research for people with multiple sclerosis, Parkinson’s and many other conditions affecting the brain. Among the study’s global luminaries is Professor David Nutt, of Imperial College London’s Centre for Psychedelic Research, which has looked into potential for psilocybin (magic mushrooms) to treat depression. Algernon, based in Vancouver, Canada, are the world’s first company to try using DMT (dimethyltryptamine) for strokes, and if they get promising results, they hope to be fast-tracked by regulators in the US. CEO Christopher Moreau told Metro.co.uk: Since we’re dealing with stroke patients, we will be using the sub-hallucinogenic dose, which in pre-clinical studies has still shown to improve neuroplasticity. ‘It will help the brain heal even though patients aren’t having the psychedelic experience, and we really don’t want that if your patient has just had a stroke.’ DMT occurs in many plants and animals, but Algernon will produce theirs synthetically (Picture: Getty Images) Algernon have been buoyed by a study last year in which blood flow was blocked off for one half of the brain in rats. Rodents who were given DMT recovered motor-function and rebuilt brain cells more efficiently and had fewer lesions on the brain. ‘We’re going to take that information now and move very quickly to test it in humans,’ Mr Moreau said. He explained how there is still ‘very little available’ for stroke victims in the immediate aftermath and that DMT could help fill the void. Part of the problem is that two of the main types of stroke are very different and require different types of treatment. Christopher Moreau, CEO of Algernon Pharmaceuticals, based in Vancouver, Canada Christopher Moreau hopes the study could open a whole new field for people with other illnesses (Picture: Algernon Pharmaceuticals) Ischemic strokes occur due to a blood clot blocking a vessel in the brain and are often treated with blood thinner. But if you did this for someone suffering from a haemorrhagic stroke – caused by bleeding in or around the brain – you could kill them. For this reason patients have to wait for a CT scan, which could take hours, leaving more time for the brain to incur damage. Mr Moreau said: ‘The sooner you can start to treat post-injury the better. DMT may not benefit hemorrhagic, we don’t know, but we’re hoping it won’t cause them any problems because then we don’t have to wait for the CT scan, we can treat in the ambulance.


Read more: https://metro.co.uk/2021/02/04/stroke-victims-to-be-given-psychedelic-drug-dmt-in-groundbreaking-study-14023757/?ito=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

Psychedelic drug DMT could help stroke victims recover by rewiring their brains faster, according the first clinical trial of its kind. It is hoped the substance, also known as the ‘the spirit molecule’, could even be given to patients as soon as they’re in the ambulance, minimising the damage and maximising their recovery. Algernon Pharmaceuticals, who set out the plan for their study this week, say participants will be given a microdose, which won’t make them ‘trip’, but will still help the neurons in their brain make new connections. If the trial proves successful and gets regulatory approval, it could open up a whole new world of research for people with multiple sclerosis, Parkinson’s and many other conditions affecting the brain. Among the study’s global luminaries is Professor David Nutt, of Imperial College London’s Centre for Psychedelic Research, which has looked into potential for psilocybin (magic mushrooms) to treat depression. Algernon, based in Vancouver, Canada, are the world’s first company to try using DMT (dimethyltryptamine) for strokes, and if they get promising results, they hope to be fast-tracked by regulators in the US. CEO Christopher Moreau told Metro.co.uk: Since we’re dealing with stroke patients, we will be using the sub-hallucinogenic dose, which in pre-clinical studies has still shown to improve neuroplasticity. ‘It will help the brain heal even though patients aren’t having the psychedelic experience, and we really don’t want that if your patient has just had a stroke.’ DMT occurs in many plants and animals, but Algernon will produce theirs synthetically (Picture: Getty Images) Algernon have been buoyed by a study last year in which blood flow was blocked off for one half of the brain in rats. Rodents who were given DMT recovered motor-function and rebuilt brain cells more efficiently and had fewer lesions on the brain. ‘We’re going to take that information now and move very quickly to test it in humans,’ Mr Moreau said. He explained how there is still ‘very little available’ for stroke victims in the immediate aftermath and that DMT could help fill the void. Part of the problem is that two of the main types of stroke are very different and require different types of treatment. Christopher Moreau, CEO of Algernon Pharmaceuticals, based in Vancouver, Canada Christopher Moreau hopes the study could open a whole new field for people with other illnesses (Picture: Algernon Pharmaceuticals) Ischemic strokes occur due to a blood clot blocking a vessel in the brain and are often treated with blood thinner. But if you did this for someone suffering from a haemorrhagic stroke – caused by bleeding in or around the brain – you could kill them. For this reason patients have to wait for a CT scan, which could take hours, leaving more time for the brain to incur damage. Mr Moreau said: ‘The sooner you can start to treat post-injury the better. DMT may not benefit hemorrhagic, we don’t know, but we’re hoping it won’t cause them any problems because then we don’t have to wait for the CT scan, we can treat in the ambulance.


Read more: https://metro.co.uk/2021/02/04/stroke-victims-to-be-given-psychedelic-drug-dmt-in-groundbreaking-study-14023757/?ito=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

Psychedelic drug DMT could help stroke victims recover by rewiring their brains faster, according the first clinical trial of its kind. It is hoped the substance, also known as the ‘the spirit molecule’, could even be given to patients as soon as they’re in the ambulance, minimising the damage and maximising their recovery. Algernon Pharmaceuticals, who set out the plan for their study this week, say participants will be given a microdose, which won’t make them ‘trip’, but will still help the neurons in their brain make new connections. If the trial proves successful and gets regulatory approval, it could open up a whole new world of research for people with multiple sclerosis, Parkinson’s and many other conditions affecting the brain. Among the study’s global luminaries is Professor David Nutt, of Imperial College London’s Centre for Psychedelic Research, which has looked into potential for psilocybin (magic mushrooms) to treat depression. Algernon, based in Vancouver, Canada, are the world’s first company to try using DMT (dimethyltryptamine) for strokes, and if they get promising results, they hope to be fast-tracked by regulators in the US. CEO Christopher Moreau told Metro.co.uk: Since we’re dealing with stroke patients, we will be using the sub-hallucinogenic dose, which in pre-clinical studies has still shown to improve neuroplasticity. ‘It will help the brain heal even though patients aren’t having the psychedelic experience, and we really don’t want that if your patient has just had a stroke.’ DMT occurs in many plants and animals, but Algernon will produce theirs synthetically (Picture: Getty Images) Algernon have been buoyed by a study last year in which blood flow was blocked off for one half of the brain in rats. Rodents who were given DMT recovered motor-function and rebuilt brain cells more efficiently and had fewer lesions on the brain. ‘We’re going to take that information now and move very quickly to test it in humans,’ Mr Moreau said. He explained how there is still ‘very little available’ for stroke victims in the immediate aftermath and that DMT could help fill the void. Part of the problem is that two of the main types of stroke are very different and require different types of treatment. Christopher Moreau, CEO of Algernon Pharmaceuticals, based in Vancouver, Canada Christopher Moreau hopes the study could open a whole new field for people with other illnesses (Picture: Algernon Pharmaceuticals) Ischemic strokes occur due to a blood clot blocking a vessel in the brain and are often treated with blood thinner. But if you did this for someone suffering from a haemorrhagic stroke – caused by bleeding in or around the brain – you could kill them. For this reason patients have to wait for a CT scan, which could take hours, leaving more time for the brain to incur damage. Mr Moreau said: ‘The sooner you can start to treat post-injury the better. DMT may not benefit hemorrhagic, we don’t know, but we’re hoping it won’t cause them any problems because then we don’t have to wait for the CT scan, we can treat in the ambulance.


Read more: https://metro.co.uk/2021/02/04/stroke-victims-to-be-given-psychedelic-drug-dmt-in-groundbreaking-study-14023757/?ito=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

Psychedelic drug DMT could help stroke victims recover by rewiring their brains faster, according the first clinical trial of its kind. It is hoped the substance, also known as the ‘the spirit molecule’, could even be given to patients as soon as they’re in the ambulance, minimising the damage and maximising their recovery. Algernon Pharmaceuticals, who set out the plan for their study this week, say participants will be given a microdose, which won’t make them ‘trip’, but will still help the neurons in their brain make new connections. If the trial proves successful and gets regulatory approval, it could open up a whole new world of research for people with multiple sclerosis, Parkinson’s and many other conditions affecting the brain. Among the study’s global luminaries is Professor David Nutt, of Imperial College London’s Centre for Psychedelic Research, which has looked into potential for psilocybin (magic mushrooms) to treat depression. Algernon, based in Vancouver, Canada, are the world’s first company to try using DMT (dimethyltryptamine) for strokes, and if they get promising results, they hope to be fast-tracked by regulators in the US. CEO Christopher Moreau told Metro.co.uk: Since we’re dealing with stroke patients, we will be using the sub-hallucinogenic dose, which in pre-clinical studies has still shown to improve neuroplasticity. ‘It will help the brain heal even though patients aren’t having the psychedelic experience, and we really don’t want that if your patient has just had a stroke.’ DMT occurs in many plants and animals, but Algernon will produce theirs synthetically (Picture: Getty Images) Algernon have been buoyed by a study last year in which blood flow was blocked off for one half of the brain in rats. Rodents who were given DMT recovered motor-function and rebuilt brain cells more efficiently and had fewer lesions on the brain. ‘We’re going to take that information now and move very quickly to test it in humans,’ Mr Moreau said. He explained how there is still ‘very little available’ for stroke victims in the immediate aftermath and that DMT could help fill the void. Part of the problem is that two of the main types of stroke are very different and require different types of treatment. Christopher Moreau, CEO of Algernon Pharmaceuticals, based in Vancouver, Canada Christopher Moreau hopes the study could open a whole new field for people with other illnesses (Picture: Algernon Pharmaceuticals) Ischemic strokes occur due to a blood clot blocking a vessel in the brain and are often treated with blood thinner. But if you did this for someone suffering from a haemorrhagic stroke – caused by bleeding in or around the brain – you could kill them. For this reason patients have to wait for a CT scan, which could take hours, leaving more time for the brain to incur damage. Mr Moreau said: ‘The sooner you can start to treat post-injury the better. DMT may not benefit hemorrhagic, we don’t know, but we’re hoping it won’t cause them any problems because then we don’t have to wait for the CT scan, we can treat in the ambulance.


Read more: https://metro.co.uk/2021/02/04/stroke-victims-to-be-given-psychedelic-drug-dmt-in-groundbreaking-study-14023757/?ito=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

Sunday, November 15, 2020

Ayahuasca Could Do Something Amazing to Your Brain, Study Shows

If we had anything other than fucking failures of stroke associations we would be assured that they would be getting human testing done for all of these to find the best one. Stroke survivors have to guess on what might work and the amounts because the stroke medical world is completely failing at their job.

Curcumin promotes neurogenesis of hippocampal dentate gyrus via Wnt/β-catenin signal pathway following cerebral ischemia in mice November 2020

Flavonoids as a Natural Enhancer of Neuroplasticity—An Overview of the Mechanism of Neurorestorative Action October 2020

Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury June 2020

Intraventricular Medium B Treatment Benefits an Ischemic Stroke Rodent Model via Enhancement of Neurogenesis and Anti-apoptosis April 2020 

Psilocybin induces time-dependent changes in global functional connectivity: Psi-induced changes in brain connectivity February 2020 

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke January 2020 

a ketogenic diet has been shown to increase neurogenesis.  February 2008 

Psychedelics can promote neural plasticity in the prefrontal cortex and expand pathways for mental health August 2018

 

How the hell do we get stroke researchers to focus on the only reason for stroke research? 100% recovery for all.

 

  The latest here in which nothing will be done because WE HAVE NO STROKE LEADERSHIP.  No one in stroke is doing a fucking thing to solve stroke, everyone is just beating around the edges or doing prediction, awareness or compensation crapola.

Ayahuasca Could Do Something Amazing to Your Brain, Study Shows

In a new study, researchers found the traditional psychoactive drug ayahuasca stimulates the growth of new brain cells in the hippocampi of research mice. The hippocampus is responsible for many memory functions, and the mice dosed with ayahuasca also performed better in a battery of memory tests.

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While ayahuasca, a hallucinogenic and often purgative tea brewed from leaves of a shrub that grows in South America, contains the psychoactive compound N, N-dimethyltryptamine (DMT), it also packs harmine and tetrahydoharmine, two compounds that form new neurons from stem cells in a petri dish, per IFL Science.

Ayahuasca is used in spiritual practices across different belief systems, and Healthline explains that the plant’s naturally occurring DMT—which can produce powerful hallucinations and visions—works in tandem with another compound that makes it more “bioavailable.” That means it’s absorbed better by the body, with less flushed out as waste afterward. Think about how calcium and vitamin D work together to increase absorption.

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DMT is the secret agent in this research, literally—besides ayahuasca, DMT is found in a variety of contexts in humans and animals. Scientists believe DMT’s chemical role is to boost and trigger certain chemical reactions in the body. And because it naturally occurs in ayahuasca, too, scientists wonder if this outside application could work inside the body the same way.