Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label RCT. Show all posts
Showing posts with label RCT. Show all posts

Tuesday, January 1, 2019

The Effect of Hypnotic Suggestion on Cognition, Sleep, Patient-Reported Outcomes, and Insight following Acquired Brain Injury

What is the downside of doing this before the additional RCT is never performed? 

The Effect of Hypnotic Suggestion on Cognition, Sleep, Patient-Reported Outcomes, and Insight following Acquired Brain Injury


The Effect of Hypnotic Suggestion on Cognition, Sleep, Patient-Reported Outcomes, and Insight following Acquired Brain Injury Hypnosis has been successfully applied in neurorehabilitation, including for motor disorders, aphasia, pain, and vertigo. However, cognitive rehabilitation using hypnosis has received little attention. Here, we report the data from two such studies on patients with chronic cognitive sequalae following acquired brain injury. Eight sessions of hypnotic suggestion yielded large effects on WAIS working memory (d = 1.65), progress on 87% of patient-reported outcomes, and four sessions reduced the need for sleep and rest with a median of 55 minutes per day. An exploratory factor analysis showed no relationship between objective improvements and perceived improvements, indicating large individual differences in the structure of the perceived improvements. This, in turn, indicate that subjective reports following hypnotic suggestion should be interpreted with caution. No adverse effects have been observed in these experiments or reported in the literature. Based on our findings and converging evidence from the literature, we conclude that hypnotic suggestion is a promising method in cognitive neurorehabilitation following acquired brain injury. However, the mechanism is currently unknown. We argue that it should be regarded as experimental until at least one further high-quality RCT is published. Data and analysis script are available at https://osf.io/sz6bw/ .

Tuesday, September 6, 2016

Effects of Robot-Assisted Therapy for the Upper Limb After Stroke A Systematic Review and Meta-analysis

And yet we still have no one writing up a stroke protocol on this. A great stroke association president would be making sure at the very least a draft protocol would be written up. It could then be critiqued and updated as necessary. But since we have fucking failures of stroke associations something as simple as this will never occur under current lack of leadership. We don't have stroke leaders because leaders actually tackle the difficult problems, they don't run away and just produce press releases. 

Effects of Robot-Assisted Therapy for the Upper Limb After Stroke A Systematic Review and Meta-analysis



  1. Janne M. Veerbeek, PhD1,2,3
  2. Anneli C. Langbroek-Amersfoort, MSc4
  3. Erwin E. H. van Wegen, PhD1,2,3
  4. Carel G. M. Meskers, PhD, MD1,2,3,5
  5. Gert Kwakkel, PhD1,2,3,5,6
  1. 1MOVE Research Institute Amsterdam, VU University Amsterdam, Amsterdam, the Netherlands
  2. 2Neuroscience Campus Amsterdam, Amsterdam, the Netherlands
  3. 3VU University Medical Center, Amsterdam, the Netherlands
  4. 4Centrum voor Fysiotherapie, Eerstelijns Centrum Beatrixpark, Ede, the Netherlands
  5. 5Northwestern University, Evanston, IL, USA
  6. 6Amsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands
  1. Janne M. Veerbeek, Department of Rehabilitation Medicine, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, the Netherlands. Email: j.veerbeek@vumc.nl

Abstract

Background. Robot technology for poststroke rehabilitation is developing rapidly. A number of new randomized controlled trials (RCTs) have investigated the effects of robot-assisted therapy for the paretic upper limb (RT-UL).  
Objective. To systematically review the effects of poststroke RT-UL on measures of motor control of the paretic arm, muscle strength and tone, upper limb capacity, and basic activities of daily living (ADL) in comparison with nonrobotic treatment.  
Methods. Relevant RCTs were identified in electronic searches. Meta-analyses were performed for measures of motor control (eg, Fugl-Meyer Assessment of the arm; FMA arm), muscle strength and tone, upper limb capacity, and basic ADL. Subgroup analyses were applied for the number of joints involved, robot type, timing poststroke, and treatment contrast.  
Results. Forty-four RCTs (N = 1362) were included. No serious adverse events were reported. Meta-analyses of 38 trials (N = 1206) showed significant but small improvements in motor control (~2 points FMA arm) and muscle strength of the paretic arm and a negative effect on muscle tone. No effects were found for upper limb capacity and basic ADL. Shoulder/elbow robotics showed small but significant effects on motor control and muscle strength, while elbow/wrist robotics had small but significant effects on motor control.  
Conclusions. RT-UL allows patients to increase the number of repetitions and hence intensity of practice poststroke, and appears to be a safe therapy. Effects on motor control are small and specific to the joints targeted by RT-UL, whereas no generalization is found to improvements in upper limb capacity. The impact of RT-UL started in the first weeks poststroke remains unclear. These limited findings could mainly be related to poor understanding of robot-induced motor learning as well as inadequate designing of RT-UL trials, by not applying an appropriate selection of stroke patients with a potential to recovery at baseline as well as the lack of fixed timing of baseline assessments and using an insufficient treatment contrast early poststroke.

Sunday, February 28, 2016

The Bobath Concept/NDT: Clarifications and Context

Wow, The Bobath concept  is an individualised response-based treatment approach. Because of that it results in difficulty in investigating the Bobath concept using traditional experimental designs such as the Randomised Controlled Trial. What a crock, if you can't create a RCT then you have no basis in even using it for therapy. Apologists in force in this posting. I guess it is unprofessional to criticize Bobath, well shit, I'm not a medical professional so if you can't prove your stuff works then you can shove it. 

Hopefully you aren't using it - NDT(Bobath) anymore  in stroke rehab when it should have been shitcanned since 2003? Physiotherapy Based on the Bobath Concept for Adults with Post-Stroke Hemiplegia: A Review of Effectiveness Studies 2003)

The Bobath Concept/NDT: Clarifications and Context 



Point by point refutation here:
Thoughts on the BBTA’s thoughts

Tuesday, October 27, 2015

Methodological Quality of Motor Intervention Randomized Controlled Trials in Stroke Rehabilitation

Did this research tell us anything useful at all? In understandable English; What the hell was the reason behind doing this and the results?
http://www.strokejournal.org/article/S1052-3057%2815%2900510-8/abstract

Amanda McIntyre, RN, and MSccorrespondence
, , , , ,
Robert Teasell, MD, FRCPC
Publication stage: In Press Corrected Proof
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Purpose

The objective of the study was to evaluate the methodological quality of motor intervention randomized controlled trials (RCTs) published in the stroke rehabilitation literature and to examine trends in quality over time.

Methods

A systematic literature search was conducted for all English articles (published up to December 2013) examining rehabilitation for motor recovery poststroke. All RCTs with a human sample, of which at least 50% had a stroke, were included in the analysis. A Physiotherapy Evidence Database (PEDro) score was assigned to assess methodological quality. A one-way analysis of variance was conducted to examine adherence to quality items overall and over time, with post hoc t-tests performed where appropriate.

Results

Six hundred seventy-six RCTs met inclusion criteria, of which 32.0% had excellent, 42.0% good, 23.1% fair, and 3.0% poor methodological qualities. The overall mean PEDro score was 6.6 ± 1.6; with scores improving significantly between 1979-1983 and 2009-2013 (5.0 ± 1.4 versus 7.0 ± 1.5; P = .0003); however, no significant improvements in individual items were found (P > .05).

Conclusions

This study showed improvements in the total methodological quality of motor intervention RCTs in stroke rehabilitation over time.??? However, no relationship was found between individual quality items and improvement over time.

Monday, December 16, 2013

randomized controlled trial (RCT) - Run your own

You know the complaints about nobody knowing a damn thing about stroke recovery. Well here's your answer. Run your own trial and show it off to your research challenged neurologist.
http://www.randomiseme.org/
The blogger who created it talks about it here;

RandomiseMe: our fun new website that lets anyone design and run a randomised controlled trial.