The final, formatted version of the article will be published soon.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 34,365 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Showing posts with label 'cost'. Show all posts
Showing posts with label 'cost'. Show all posts
Wednesday, July 8, 2026
Cost-Effectiveness of Post-Acute Stroke Rehabilitation From a U.S. Healthcare Payer Perspective: Inpatient Rehabilitation Facilities Versus Skilled Nursing Facilities
Please cite this article as: Heather Hayes DPT, PhD , Minkyoung Yoo PhD , Richard Nelson PhD ,
Cost-Effectiveness of Post-Acute Stroke Rehabilitation From a U.S. Healthcare Payer Perspective:
Inpatient Rehabilitation Facilities Versus Skilled Nursing Facilities, Archives of Physical Medicine and
Rehabilitation (2026), doi: https://doi.org/10.1016/j.apmr.2026.06.027
This is a PDF of an article that has undergone enhancements after acceptance, such as the ad
dition of a cover page and metadata, and formatting for readability. This version will undergo addi
tional copyediting, typesetting and review before it is published in its final form. As such, this ver
sion is no longer the Accepted Manuscript, but it is not yet the definitive Version of Record; we are
providing this early version to give early visibility of the article. Please note that Elsevier’s sharing
policy for the Published Journal Article applies to this version, see: https://www.elsevier.com/about/
policies-and-standards/sharing#4-published-journal-article. Please also note that, during the produc
tion process, errors may be discovered which could affect the content, and all legal disclaimers that
apply to the journal pertain.
©2026 Published by Elsevier Inc. on behalf of the American Congress of Rehabilitation Medicine
Tuesday, May 12, 2026
Economic evaluations of outpatient stroke rehabilitation models: a systematic review of evidence, methods, and gaps
Survivors want recovery statistics NOT COST!
Economic evaluations of outpatient stroke rehabilitation models: a systematic review of evidence, methods, and gaps
Ahmad Al Miaraja,b Send email to ahmad.miaraj.22@ucl.ac.uk ∙ Sonila M. Tominia ∙ Nick Wardc ∙ Rodolfo Catenaa
Affiliations & Notes
Background
Stroke imposes an ongoing burden on patients and health systems, making outpatient rehabilitation essential. The economic efficiency of alternative outpatient models remains uncertain, complicating resource allocation. We systematically reviewed and critically appraised full economic evaluations of outpatient stroke rehabilitation to synthesise evidence on reported cost-effectiveness, assess how costs and outcomes have been measured, and identify key methodological limitations and evidence gaps.
Methods
We conducted a PRISMA-guided systematic review (PROSPERO: CRD420251151991) of full economic evaluations of outpatient stroke rehabilitation. Embase, Emcare, Medline, CINAHL, Cochrane Library, Web of Science, and PubMed were searched, with publication coverage including all available studies published prior to September 2025. Eligible studies included adults with ischemic or haemorrhagic stroke undergoing outpatient rehabilitation and reporting full economic evaluations. We excluded inpatient-only rehabilitation, transient ischaemic attack, partial evaluations, reviews, and non-English publications. Two reviewers independently screened, extracted, and appraised studies. Risk of bias (RoB 2, ROBINS-I) and methodological quality (Drummond checklist) were assessed, with data narratively synthesised by rehabilitation model and evaluation type.
Findings
The search yielded 1800 records, of which 27 studies met inclusion criteria. Across studies, community-based, home-based, and early supported discharge rehabilitation models frequently demonstrated favourable cost-effectiveness when compared with inpatient or outpatient clinic-based rehabilitation. Study settings were global, with over one-third from the UK. Most were randomised controlled trials (56%), with cost-effectiveness analyses predominating (63%). Community- and home-based rehabilitation were most common (each 30%), followed by outpatient clinic-based (22%), early supported discharge (11%), and telerehabilitation (7%). Outcomes clustered into health-related quality of life (41%), functional recovery (37%), and process measures (22%). Methodological quality was mostly moderate (16/27), with seven high and four low. RCTs showed some reporting concerns, while most non-randomised studies carried serious risk of bias.
Interpretation
Evidence from existing economic evaluations suggests that shifting stroke rehabilitation toward outpatient and community-based rehabilitation models may demonstrate more favourable cost-effectiveness profiles in certain contexts, while evidence on telerehabilitation remains limited. However, these findings should be interpreted with caution due to substantial heterogeneity across study designs, comparators, outcomes, and economic evaluation methods. To better inform decision-making, future studies should adopt standardised outcome measures, extend follow-up, and generate context-specific economic evidence, particularly in low- and middle-income countries.
Monday, April 13, 2026
Budget Impact Analysis of Kickstart Exoskeletal Technology for Stroke Rehabilitation within the Ontario Hospital System
Stroke survivors don't care about 'cost'. They want to know 100% RECOVERY EFFECTIVENESS! Are you that blitheringly stupid? What are the EXACT RECOVERY RESULTS? This just seems to be get them somewhat mobile so we can kick them out the door!
Of course, this technology has been out there a while and the incompetence shown in how long to bring it in is FUCKINGLY IMPRESSIVE!
- kickstart
(9 posts to April 2015)
Budget Impact Analysis of Kickstart Exoskeletal Technology for Stroke Rehabilitation within the Ontario Hospital System
Danielle M. Dobney, PhD, MSc, CAT, Gaven Ren, BKin, Samena Rashid-Mohamed , BSc, MHSc,
CHE, Danvir Sandhu , BSc (Candidate), Eimerie Mengulloe , Diploma in Digital
Communications and Media
Affiliations
University of Toronto, Toronto, Canada
University of Western Ontario, London, Canada
University of Waterloo, Waterloo, Canada
Trent University, Peterborough, Canada
Study Context
Ontario Hospital System, Canada
Corresponding Author
Danielle Dobney
Email: ddobney@kickstartcanada.com
Running Title
Budget Impact of Kickstart in Stroke Rehabilitation
Keywords
stroke rehabilitation, budget impact analysis, health economics, exoskeleton, Ontario
Word count
4765 (excluding title page and references)
Abstract:
Background: Stroke places a significant and growing economic burden on the Ontario health
care system, particularly within inpatient rehabilitation. Technologies that accelerate functional
recovery may improve both patient outcomes and system efficiency.
Objective:
To estimate the budget impact of implementing Kickstart technology in Ontario
hospitals.
Methods:
A budget impact model was developed using Ontario-specific attributable stroke
costs, adjusted to 2026 values using healthcare inflation. Hospital scenarios were modeled for
community hospitals and regional stroke centres using published admission volumes. Savings
were estimated based on reductions in inpatient rehabilitation length of stay (1-5 days) and a
per-diem cost range of $800 - $1,200 CAD. A 35% eligibility rate was applied to reflect patients
meeting clinical criteria for device use.
Results:
The projected 2026 attributable cost of stroke was $39,455 CAD per patient, including
$8,492 for inpatient rehabilitation. In community hospitals, annual savings ranged from $44,000
to $330,000, with a moderate estimate of $165,000. In regional centres, savings ranged from
$112,000 to $840,000, with a moderate estimate of $420,000. Device costs were offset after
approximately 5–9 patients.
Conclusion:
Kickstart implementation may yield substantial cost savings by reducing
rehabilitation length of stay while improving system capacity and efficiency. These findings
support further real-world evaluation to validate projected benefits.
Wednesday, July 9, 2025
A Decision-Analytic Model to Evaluate Cost-Effectiveness of Regional Implementation of a Mobile Stroke Unit.
Stroke survivors don't care about 'cost'. They want to know 100% RECOVERY EFFECTIVENESS! Are you that blitheringly stupid?
A Decision-Analytic Model to Evaluate Cost-Effectiveness of Regional Implementation of a Mobile Stroke Unit.
Peter L van Hulst, Ruben M van de Wijdeven, Esmee Venema, Florentina M E Pinckaers
Neurology. 2025 Aug 12; 105(3):
BACKGROUND AND OBJECTIVES
Mobile stroke units (MSUs) have the potential to improve functional outcome of ischemic stroke patients, through shortening onset-to-treatment times. Previous cost-effectiveness studies have limited generalizability to nonmetropolitan settings and did not evaluate cost-effectiveness over a lifetime horizon. We aimed to develop a regionally adaptable decision-analytic model, to evaluate cost-effectiveness of MSU implementation and to identify the optimal dispatch scenario.METHODS
We developed a generalizable state-transition microsimulation model with modifiable region-specific parameters and dispatch characteristics to evaluate the lifetime cost-effectiveness from a health care perspective of 1-year MSU implementation. We used the southwest of the Netherlands (1,770,000 inhabitants, 1,592 km2, 7 primary stroke centers, 2 thrombectomy-capable stroke centers) as an example. Region-specific input parameters for the model, such as population density, age distribution, and driving times, were obtained at the level of postal codes. We developed a virtual cohort of suspected stroke patients based on age-dependent stroke risks and the number of inhabitants per postal code. We compared the combined dispatch of an MSU and emergency medical services (EMS) with dispatch of EMS alone for patients with onset-to-alarm time <6 hours, living within the catchment area of the MSU. In the base case analysis, the MSU could be dispatched to all postal codes in the study region between 7.00 am and 11.00 pm from a central dispatch site. We assessed the long-term cost-effectiveness through incremental net monetary benefits (iNMBs). Discount rates were 1.5% for effects and 4.0% for costs.RESULTS
In the base case scenario, the MSU was dispatched to 2,080 of 3,628 patients (57.3%) with a suspected stroke and onset-to-alarm time <6 hours, resulting in a lifetime gain of 399 (95% CI 384-414) additional quality-adjusted life years, €3.9 million (95% CI €3.5 million-€4.3 million) cost savings, and an iNMB of €23.9 million (95% CI €22.8 million-€24.9 million). A smaller catchment area for MSU dispatch was associated with increased cost-effectiveness.DISCUSSION
Adding an MSU to the dispatch strategy for suspected stroke patients is expected to be cost-effective in our region. Our model facilitates evaluation of the cost-effectiveness of MSU implementation in different regions, settings, and scenarios with varying characteristics.Source: Neurology
Saturday, May 24, 2025
Empowering stroke recovery with upper limb rehabilitation monitoring using TinyML based heterogeneous classifiers
A complete waste of time and effort!
Empowering stroke recovery with upper limb rehabilitation monitoring using TinyML based heterogeneous classifiers
Scientific Reports volume 15, Article number: 18090 (2025) Cite this article
Abstract
Stroke is one of the leading causes of disability worldwide, with approximately 70% of survivors experiencing motor impairments in the upper limbs, significantly affecting their quality of life. Home-based rehabilitation offers a cost-effective approach(Survivors don't care about cost, they want to know:WILL THIS DELIVER RECOVERY? Anything else is useless as is this research! Measurements don't deliver recovery; EXACT PROTOCOLS DO! GET THERE!)) to improving motor function, but it faces challenges, including inaccurate movement reporting, lack of real-time feedback, and the high cost of rehabilitation equipment. Therefore, there is a need for affordable, lightweight home-based rehabilitation monitoring systems. This paper presents an intelligent wearable sensor system that utilizes TinyML AI technology to classify eight upper limb rehabilitation movements with minimal sensors. The system is designed for patients with upper limb impairments who retain antigravity voluntary movement, enabling them to monitor rehabilitation progress at home. The study recruited 10 healthy volunteers(But you didn't have stroke survivors demonstrate bad movements so you could figure out the protocol to get from bad to good movement. DOESN'T ANYONE IN STROKE KNOW HOW TO THINK AT ALL? to perform rehabilitation movements, creating a standardized dataset for model training. Data normalization, preprocessing, model training, and deployment were carried out using the Edge Impulse platform. A hybrid classifier, combining multilayer perceptron and k-means clustering, achieved 96.1% training accuracy, 95.09% testing accuracy, and 88.01% deployment accuracy. The proposed TinyML-based system shows promising potential for home-based rehabilitation of stroke patients.
Introduction
Cerebral apoplexy, commonly referred to as stroke, is one of the principal aetiologies of enduring disabilities worldwide1. Statistical analyses indicated that approximately 70% of individuals who recovered from stroke experienced motor dysfunctions after discharge from medical facilities, with upper limb hemiparesis being the most prevalent complication. This impairment significantly hampers the ability of stroke survivors to perform activities of daily living (ADL)2,3, thereby imposing profound psychological and financial distress upon patients and their kin.
Empirical evidence suggests that prolonged and consistent rehabilitation training can significantly ameliorate motor functional impairments resulting from stroke4,5. However, the vast majority of stroke survivors lack the resources necessary for sustained clinical rehabilitation, and the rehabilitation process is hampered by factors such as time, distance, costs, the scarcity of specialists, and limited clinical facilities6,7,8,9. Studies have indicated that home-based rehabilitation represents a more sustainable model of recovery, facilitating more effective promotion of long-term rehabilitation training for patients and transitioning care services towards a decentralized model10,11,12, which is divergent from traditional clinical therapeutic approaches13,14. Compared with hospital-based rehabilitation, home rehabilitation offers greater flexibility and autonomy, affording patients substantial amounts of time for self-directed training, and home-based recovery has been shown to reduce rehabilitation healthcare costs by up to 15%15. Nonetheless, for patients receiving rehabilitation therapy within the home environment, accurately assessing the quality and quantity of rehabilitation movements poses a significant challenge. Research has documented patients’ difficulties in precisely reporting the quantity and quality of exercises performed16,17,18, as well as their struggles to adhere to rehabilitation training over extended periods16. Consequently, the classification of rehabilitation movements has emerged as a pressing issue that needs addressing in the context of home-based rehabilitation.
Rapid advancements in artificial intelligence (AI) technologies are pivotal in supporting decentralized care models. Specifically, the development of unobtrusive motion capture technologies to establish simple, safe, effective, and objective systems for movement classification has become a strategic application in supporting remote home-based rehabilitation models4,19. Traditional systems for movement classification include (1) camera-based systems20,21,22, among which depth cameras, exemplified by Kinect23, have achieved significant milestones in the domain of rehabilitation motion recognition24,25,26,27. However, camera-based solutions necessitate ample, unobstructed observational space to monitor participants, a requirement that is challenging to meet outside laboratory environments28,29. Moreover, the deployment of visual recognition technologies within domestic settings may trigger privacy invasion concerns30,31. (2) Wearable-based inertiiial sensor systems, which employ either single or multiple inetial measurement units (IMUs), facilitate the determination of each limb’s position by resolving the corresponding kinematic equations32,33,34.
Inertial motion analysis has attracted increasing interest in recent decades because of its advantages over classical optical systems35. Owing to their integrative capabilities, low cost, and ease of implementation, IMUs are extensively employed for monitoring rehabilitation exercises within home settings36,37,38,39. Table 1 provides a detailed presentation of the relevant works associated with this study, including achievements in movement classification using either a single or multiple sensors. For example, Zinnen et al.40 reported a classification accuracy of 93% for 20 movements via a five-device system and an accuracy of 86% with two wrist devices, covering actions such as manipulating various car doors and a writing task. Zhang et al.41 introduced a two-device framework that achieved 97.2% accuracy in classifying four arm movements. Lui and Menon33, Wang et al.42, Alessandrini et al.43, and Li et al.44 all rely on multiple sensors for classification. Similarly, studies by Basterretxea et al.45, Xu and Yuan46, and Choudhury et al.47 also demonstrate high accuracy, with substantial diversity in the classified movements. However, as shown in the relevant studies listed in Table 1, few studies have achieved high-precision motion classification using a single sensor. Multi-device systems are generally more complex than single-device setups are, particularly when devices are affixed to multiple limbs or when interdevice calibration is needed. Whenever possible, a single-device system is preferred due to its ease of wearability and configuration33. The rapid development of machine learning algorithms has made it possible to achieve rehabilitation movement classification using a single inertial sensor. For example, Zhang et al.48 achieved an accuracy of 96.1% for nine activities among healthy participants, including actions such as walking, running, sitting, and standing. In another study, Khan et al.49 achieved a precision of 97.9% using chest-mounted devices for 15 movements across various activities (e.g., lying, sitting, standing, and transitions among these postures). The rapid advancement of machine learning algorithms has facilitated the implementation of rehabilitation movement classification via a single inertial sensor. Tseng et al.50 reported a single-device system that achieved a classification accuracy of 93.3% for three movements associated with door opening in a study involving five healthy participants. Zhang et al.51 presented a system employing a solitary IMU for discerning six-arm manoeuvres among fourteen stroke subjects, with classification accuracies of 99.4% with an innovative algorithm and 98.8% when an SVM framework was used. These manoeuvres, which encapsulate four of the human arms’ seven degrees of freedom, include flexion and extension at the shoulder joint, signifying the arm’s forward and backwards motion; abduction and adduction at the same joint, indicating lateral movement away from and towards the torso; pronation and supination of the forearm, involving rotational movement to orient the palm downwards and upwards, respectively; and flexion and extension at the elbow joint, denoting the arm’s bending and straightening. This delineation underscores the integral relationship of movements with specific joint actions, which are crucial for comprehensive upper limb rehabilitation in stroke recovery.
More at link.
Saturday, April 26, 2025
Cost-Effectiveness Analysis of Early Minimally Invasive Removal of Intracerebral Hemorrhage
'Cost' NOT RECOVERY! You're fired along with your mentors and senior researchers!
Cost-Effectiveness Analysis of Early Minimally Invasive Removal of Intracerebral Hemorrhage
Janel Hanmer, MD, PhD https://orcid.org/0000-0001-6159-2482 hanmerjz@upmc.edu, Jonathan Arnold, MD, MS https://orcid.org/0000-0003-1185-555X, Alex Hall, DHSc, MS https://orcid.org/0000-0001-8532-524X, Jonathan J. Ratcliff, MD, MPH https://orcid.org/0009-0006-1274-2417, Jason W. Allen, MD, PhD https://orcid.org/0000-0002-5274-1105, Michael Frankel, MD, David W. Wright, MD, Daniel L. Barrow, MD https://orcid.org/0000-0003-0413-7883, Gustavo Pradilla, MD https://orcid.org/0000-0002-3661-3269, and Kenneth J. Smith, MD, MS for the ENRICH Trial InvestigatorsAuthor Info & Affiliations
Abstract
BACKGROUND:
Supratentorial
intracerebral hemorrhage (ICH) is common and often devastating. In a
randomized controlled trial, ICH evacuation with minimally invasive
trans-sulcal parafascicular surgery (MIPS) improved functional outcomes
at 180 days compared with medical management (MM), primarily in patients
with lobar hemorrhages. The cost-effectiveness of MIPS compared with MM
is explored.
METHODS:
A
Markov model compared costs and outcomes using ENRICH trial (Early
Minimally Invasive Removal of Intracerebral Hemorrhage) data for MIPS
versus MM over the 6-month trial duration. Costs were $2020 and
effectiveness was quality-adjusted life years. Monthly model transitions
between modified Rankin Scale score health states were estimated from
trial data. Costs were obtained from US databases and literature. MIPS
device costs were $5705/patient. Primary outcomes were total hospital
costs from the hospital perspective and the incremental
cost-effectiveness ratio between MIPS and MM (ie, the 6-month cost
difference between strategies divided by quality-adjusted life year
difference) for the healthcare perspective for patients with lobar ICH.
Sensitivity analyses were performed.
RESULTS:
From
the hospital perspective, MIPS costs were $2782 less per patient than
MM ($74 252 versus $77 034), with MIPS having decreased the intensive
care unit hospital length of stay, non-MIPS neurosurgery, mortality, and
rehospitalization. From the healthcare perspective, including hospital
and nonhospital costs, MIPS in lobar ICH cost $8850 less and gained
0.068 quality-adjusted life year per patient compared with MM; thus MIPS
was dominant (less costly and more effective). Results were robust to
individual parameter variation over plausible ranges and, with all
parameters varied simultaneously in a probabilistic sensitivity
analysis, MIPS was dominant in >93% of 10 000 model iterations and
favored in >99% at $100 000/quality-adjusted life year gained (a
common US benchmark).
CONCLUSIONS:
In
the ENRICH randomized controlled trial, MIPS cost less and was more
effective compared with MM from both hospital and healthcare
perspectives for patients with lobar ICH.
REGISTRATION:
Unique identifier: NCT02880878.
Graphical Abstract
Get full access to this article
Sunday, April 6, 2025
Application of Systematic Assessment of Rehabilitation Situation (STARS) Framework for Stroke Rehabilitation in the United States of America
WOW! Cost instead of results and recovery! That means that the WHO doesn't know what it's doing either! Does ANYONE in the medical field have two functioning neurons to rub together for a spark of intelligence?
Application of Systematic Assessment of Rehabilitation Situation (STARS) Framework for Stroke Rehabilitation in the United States of America
Abstract
Purpose of Review
The World Health Organization (WHO) Systematic Assessment of Rehabilitation Situation (STARS) tool was developed to facilitate strategic planning and prioritization of rehabilitation as part of a larger effort to guide countries on better integrating rehabilitation in health systems. In this manuscript, we apply STARS to the United States and illustrate the challenges and opportunities for advancing discussions for prioritizing rehabilitation services to address the needs of Americans.
Recent Findings
Rehabilitation services address a wide spectrum of needs for individuals experiencing limitations in everyday physical, mental, and social functioning due to injury, aging or a health condition. Nearly half of all Americans could benefit from receiving rehabilitation services; yet, limitations in the awareness of individual and societal benefits, the prioritization of rehabilitation care in the continuum of healthcare delivery, and geographic availability of rehabilitation professionals have collectively limited access to this essential service.
Summary
This assessment of rehabilitation services identified several gaps in coordinated leadership, governance, and financing, which can be used by decision-makers, providers, and other shareholders to come up with cost-effective solutions for the expansion of rehabilitation services to meet the needs in the U.S.
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Saturday, February 15, 2025
Cost-Effectiveness of Telerehabilitation Compared to Traditional In-Person Rehabilitation: A Systematic Review and Meta-Analysis
Survivors don't give a flying fuck about cost; what are the recovery results? Are you THAT BLITHERINGLY STUPID?
Cost-Effectiveness of Telerehabilitation Compared to Traditional In-Person Rehabilitation: A Systematic Review and Meta-Analysis
Published: February 14, 2025
DOI:
10.7759/cureus.79028
Abstract
This systematic review and meta-analysis evaluated the cost-effectiveness of telerehabilitation compared to traditional in-person rehabilitation. A comprehensive search of PubMed, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Ovid databases identified 14 eligible studies. The analysis followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, assessing economic outcomes using incremental cost-effectiveness ratios (ICERs) and quality-adjusted life years (QALYs).
Findings indicate that telerehabilitation was cost-effective in three out of 14 studies included in the cost-effectiveness analysis. The mean ICER for telerehabilitation compared to traditional rehabilitation varied, with a probability of cost-effectiveness reaching 90% at a willingness-to-pay (WTP) threshold of $30,000 per QALY. However, at a WTP threshold of $0, the probability of cost-effectiveness remained low, suggesting that telerehabilitation does not always dominate in cost-effectiveness analyses.
The study highlights the potential of telerehabilitation to provide similar or improved health outcomes compared to traditional rehabilitation while reducing travel costs and enhancing patient access. Increased patient satisfaction, reduced hospital readmissions, and improved adherence to rehabilitation protocols contributed to the economic benefits observed. However, methodological heterogeneity across studies remains a limitation.
Given the growing adoption of digital health technologies, telerehabilitation presents a viable and economically efficient alternative to in-person rehabilitation. Policymakers should consider integrating telerehabilitation into routine healthcare services, particularly in resource-constrained settings, to optimize cost-effectiveness and enhance accessibility. Further research should focus on standardizing cost-effectiveness evaluation methods to strengthen evidence for large-scale implementation.
Introduction & Background
Telehealth is any use of technology to communicate and exchange information among patients and health practitioners across a distance [1]. Telerehabilitation is a kind of telehealth intervention where rehabilitation services are offered via phone, the Internet, and remote devices [2]. Rehabilitation has been used in different disease conditions such as schizophrenia [3], diabetes mellitus [4], dementia [5], etc., for a long period. Telerehabilitation is found to be effective in diseases like heart failure [6], stroke [7], hip replacement [8], total knee arthroplasty [9], chronic low back pain [10], breast cancer [11], etc. There has been a huge increase in the use of telehealth globally since COVID-19 [12,13]. Telerehabilitation can improve accessibility [14], utilization of healthcare services [15], improving health outcomes, reducing health inequalities [16], and reducing the waiting time and need for travel [17,18]. It has also improved patient and provider satisfaction and augmented clinical effectiveness [19,20]. Numerous systematic reviews have been conducted to assess the impact of telerehabilitation on patient outcomes [21], while others have examined its effectiveness across various types of healthcare providers [22]. Various studies have been done on the effectiveness of telerehabilitation in different disease conditions, like brain injury [23], stroke [24], and cardiovascular diseases [25].
One of the significant challenges associated with integrating technology into healthcare is the rising cost of healthcare services. Healthcare costs are increasing due to progress in medical technology, demographic aging, an increasing number of healthcare services, and provider-induced demand [26]. Therefore, health providers should have the goal of achieving high-quality services while restraining costs. Economic evaluations like cost-effectiveness analysis (CEA), cost-utility analysis (CUA), and cost-benefit analysis (CBA) play a crucial role in healthcare by systematically assessing the costs and outcomes associated with various interventions. These evaluations help healthcare providers and policymakers make informed decisions to determine which interventions provide the best value for money.
To our knowledge, no published literature comprehensively summarizes the cost-effectiveness of telerehabilitation. This study seeks to thoroughly assess, analyze, and synthesize the published information on the cost-effectiveness of telerehabilitation services. Our objective is to provide a comprehensive overview of the economic impact of telerehabilitation, identifying key areas where telerehabilitation has proven to be cost-effective and highlighting gaps where further research is needed. This will help inform healthcare providers, policymakers, and stakeholders about the potential financial benefits of integrating telerehabilitation into their services and guide future research priorities in this evolving field.
More at link.
Wednesday, February 5, 2025
Article Commentary: “Endovascular Thrombectomy Alone for Large Vessel Occlusion: A Cost-Effectiveness Evaluation Based on Meta-Analyses”
WRONG, WRONG, WRONG! Survivors don't care about cost, they want effectiveness. How close does this get them to 100% recovery? Are you that blitheringly stupid?
If you can't do research that gets survivors recovered; GET THE HELL OUT!
Article Commentary: “Endovascular Thrombectomy Alone for Large Vessel Occlusion: A Cost-Effectiveness Evaluation Based on Meta-Analyses”
- Rami Z. Morsi , MD , @DrRamiMorsi
The management of acute ischemic stroke due to large vessel occlusion (LVO) has evolved significantly in recent years. While the combination of intravenous thrombolysis (IVT) with alteplase and endovascular thrombectomy (EVT) remains the standard of care, questions have arisen about the added benefit of IVT in patients who can receive prompt EVT. This debate stems from concerns about potential delays to EVT and increased risk of intracranial hemorrhage with IVT. To address this question, six randomized controlled trials (RCTs) have compared EVT alone to IVT plus EVT in LVO patients. While two trials (DIRECT-MT and DEVT) suggested non-inferiority of EVT alone, the others (SKIP, MR CLEAN-NO IV, SWIFT-DIRECT, and DIRECT-SAFE) could not definitively rule out potential benefits of IVT before EVT. Given this equipoise, cost-effectiveness becomes an important consideration in clinical decision-making.
Nguyen and colleagues recently conducted a cost-effectiveness analysis comparing EVT alone to IVT plus EVT for LVO patients presenting directly to EVT-capable centers in the Netherlands. Their study utilized a Monte Carlo simulation with a 15-year time horizon, incorporating data from a hypothetical cohort of 10,000 patients treated within 4.5 hours of symptom onset.
The authors based their primary analysis on intention-to-treat data from the six aforementioned trials, using published modified Rankin Scale distributions from a patient-level meta-analysis. They found that IVT before EVT resulted in slightly higher costs ($2,817 extra per patient) but also a modest gain in quality-adjusted life years (0.05 QALYs per patient). This translated to an incremental cost-effectiveness ratio of $62,287 per QALY.
Probabilistic sensitivity analysis revealed considerable uncertainty in the results. At willingness-to-pay thresholds of $52,500 and $84,000 per QALY, IVT before EVT had probabilities of being cost-effective of 45% and 54%, respectively. The scatter plot of simulations (Figure 2) visually demonstrates this uncertainty, with results distributed across quadrants representing both higher and lower effectiveness for IVT plus EVT.
The authors also conducted a comprehensive analysis of the cost-effectiveness of endovascular thrombectomy (EVT) alone versus intravenous thrombolysis (IVT) with alteplase before EVT in patients with large vessel occlusion (LVO). Their approach included three additional scenarios to assess the robustness of their findings: (1) post hoc modified as-treated analysis from six RCTs; (2) intention-to-treat analysis from European RCTs (MR CLEAN-NO IV and SWIFT-DIRECT); and (3) intention-to-treat analysis from a Dutch RCT (MR CLEAN-NO IV). These scenarios yielded varying probabilities of cost-effectiveness for IVT with alteplase before EVT. At the $52,500 willingness-to-pay (WTP) threshold, the probabilities were 64%, 81%, and 50% for scenarios 1, 2, and 3, respectively. At the higher $84,000 WTP threshold, these probabilities increased to 79%, 91%, and 67%. A key finding of this study was the impact of variable functional outcomes, as measured by modified Rankin Scale (mRS) distributions, on cost-effectiveness results. This variability across different scenarios emphasizes the need for careful consideration of patient populations and treatment settings when interpreting and applying cost-effectiveness data.
The study had several limitations that warrant consideration: (1) The use of mRS distributions from published meta-analyses may have restricted certain subgroup analyses; (2) the short follow-up period in the MR CLEAN trial could have affected the accuracy of long-term transition probabilities; (3) the absence of cost data for adverse events, such as symptomatic intracranial hemorrhage management, may have impacted the overall cost estimates; (4) the analysis focused solely on alteplase, as tenecteplase is not currently used for LVO patients in the Netherlands.
Despite these limitations, the study results suggest potential cost-effectiveness, particularly at higher WTP thresholds, and provide valuable insights into the potential cost-effectiveness of IVT before EVT in the Dutch healthcare context. Future research directions should include evaluating the cost-effectiveness of tenecteplase before EVT compared to EVT alone, identifying specific subgroups of patients undergoing EVT who may derive greater economic benefit from prior IVT, and conducting longer-term follow-up studies to improve the accuracy of transition probabilities and cost estimates.
Sunday, January 5, 2025
Cardiac Rehabilitation for Persons with Stroke: A Cost-Effectiveness Analysis
I'd fire anyone working on cost rather than getting recovery protocols created.
You'll want those 100% recovery protocols when you are the 1 in 4 per WHO that has a stroke!
The latest here:
Cardiac Rehabilitation for Persons with Stroke: A Cost-Effectiveness Analysis
Abstract
Objective
To
investigate the cost-effectiveness of a cardiac rehabilitation program
in individuals with stroke compared with customary care.
Design
A
Markov model was created using a 30-year time horizon, with cycle
lengths of 1 year to determine the effectiveness and cost-effectiveness
of a cardiac rehabilitation program in persons with stroke. Input
parameters were based on recently published literature. Health states
were defined as degree of disability evaluated by the modified Rankin
scale score. Costs were based on recent cost-effectiveness analyses and
inflated to 2024 US Dollars using the medical care component of the US
Consumer Price Index.
Setting
Outpatient ambulatory setting
Participants
Persons with mild disability after ischemic stroke
Intervention
A model comparing cardiac rehabilitation versus usual care was created.
Main Measures
Quality-adjusted
life years (QALYs) were used to measure the effectiveness of cardiac
rehabilitation versus usual care. The cost-effectiveness of cardiac
rehabilitation versus usual care was compared with respect to
incremental costs, incremental effectiveness, and incremental
cost-effectiveness ratios (ICERs).
Results
Cardiac
rehabilitation was the superior strategy, resulting in higher
incremental effectiveness of 3.28 QALY at an increased incremental cost
of $5704. The ICER was $1740/QALY. A two-way sensitivity analysis of
these variables had no change, with cardiac rehab remaining the optimal
strategy.
Conclusions
While
numerous studies and systematic analyses have reported compelling
evidence of the clinical benefits of cardiac rehabilitation for patients
with stroke, the current study contributes to the existing body of
literature, demonstrating that cardiac rehabilitation is also
cost-effective in the stroke population.
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Friday, September 6, 2024
Financial Analysis of a Locomotor Exercise Trial for Post-Stroke Recovery: Insights from the HIT Stroke Trial
Survivors don't give a flying fuck about costs; they want 100% recovery! GET THERE!
Financial Analysis of a Locomotor Exercise Trial for Post-Stroke Recovery: Insights from the HIT Stroke Trial
- University of Kansas Medical Center, Kansas City, United States
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Background:
Navigating the complexities of post-stroke recovery trials requires addressing challenges in participant recruitment and retention and effective resource management to ensure trial success. The aim of this study was to examine the financial requirements associated with conducting the Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke (HIT Stroke Trial) at a single site encompassing a wide catchment area, recognizing the intricate challenges of participant recruitment and retention inherent in post-stroke recovery trials.
Methods:
To determine cost, study expense reports were gathered and divided into seven categories: recruitment, screening assessments, baseline assessments, intervention, outcome assessments, retention, and oversight. Categories were then further divided into chronological order for initial contact and prescreening, consenting, initial screening, and baseline testing. The 12-week intervention was divided into 4-week blocks: intervention block 1, post 4-week outcome testing, intervention block 2, post 8-week outcome testing, intervention block 3, and post 12-week outcome testing.
Results:
Total direct cost for site execution was $539,768 with cost per participant approximated as $35,984. Oversight costs accounted for 65.8% of the budget at $355,661. To achieve goals related to inclusive participant recruitment ($21,923) and retention ($28,009), our site costs totaled $49,932. Direct study-related costs included screening assessments ($5,905), baseline assessments ($15,028), intervention ($76,952), and outcome assessments ($36,288).
Discussion:
Clinical trials focusing on walking rehabilitation and exercise, particularly those requiring multiple assessment visits, demand rigorous oversight. This cost analysis provides important and critical insight into the expenses required to successfully execute an exercise-based walking rehabilitation trial in the United States.
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Emily M. Hazen