Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label Dead wood. Show all posts
Showing posts with label Dead wood. Show all posts

Wednesday, September 23, 2026

Early gait segments may be sufficient: fall risk assessment does not require steady-state walking

 What is your competent? doctors EXACT FALL PREVENTION PROTOCOL? Doesn't have one I bet; A FIREABLE OFFENSE! We have to forcefully clean out a lot of incompetent dead wood in stroke.

Early gait segments may be sufficient: fall risk assessment does not require steady-state walking

    We’re sharing this article early to provide faster access to peer-reviewed, accepted research. It is citable and carries a permanent DOI. This version is subject to further edits and will be replaced automatically by the final Version of Record. All legal disclaimers apply.

    Abstract

    Falls remain a significant health concern for older adults, highlighting the need for efficient and accurate fall risk screening. Although wearable inertial measurement units provide accessible gait analysis, it remains unclear whether fall-history classification requires gait parameters computed over fully stabilized walking sequences or whether discriminative information may already be present in the early portion of the walking sequence before parameters converge. This study analyzes foot-mounted IMU data from two independent cohorts: the publicly available GSTRIDE dataset and a private dataset collected by our team. After preprocessing, the analytical samples included 147 GSTRIDE participants (71 fallers and 76 non-fallers) and 95 participants from our dataset (16 fallers and 79 non-fallers) recruited from senior living facilities. Faller status was defined using retrospective fall-history labels. Across cumulative and sliding window feature extraction strategies, variability-based gait parameters required a large number of strides to achieve stable reliability, particularly among fallers. Nevertheless, strong discriminative potential was consistently observed using gait segments obtained prior to full parameter stabilization. Window-based statistical analyses further showed that significant early-window variability differences were present in the GSTRIDE dataset but not in our dataset, despite comparable classification trends. These findings indicate that full parameter stabilization is not a prerequisite for effective fall-history classification. Instead, gait segments from the early portion of walking sequences can provide useful discriminative information, offering a practical alternative to conventional approaches that rely on prolonged steady-state walking recordings.

    Wednesday, August 19, 2026

    Nigerian Innovator Develops Robotic Rehabilitation Glove For Stroke Survivors

     Ask your competent? doctor if spastic fingers can get in these.

    Have your competent? doctor validate that this is better than all these other ones out there. Can't do that? PURE INCOMPETENCE! I take no prisoners in getting stroke solved to 100% recovery. Aren't even trying to get there, then REMOVE THAT DEAD WOOD!

    Nigerian Innovator Develops Robotic Rehabilitation Glove For Stroke Survivors

    Thursday, June 18, 2026

    Inside the Quest to Make Old Cells Young Again

     Ask your competent? doctor about the epigenetic restoration program. NO knowledge is grounds for IMMEDIATE DISMISSAL! I take no prisoners in trying to get stroke solved! A hell of a lot of dead wood needs to be removed!

    Inside the Quest to Make Old Cells Young Again

    Saturday, June 6, 2026

    Altered temporal variability-based functional reorganization of brain networks predicts motor outcome after stroke

     Predicting recovery rather than delivering recovery IS COMPLETE INCOMPETENCE!

    I take no prisoners in trying to get stroke solved and that means a lot of dead wood needs to be removed. 

    Altered temporal variability-based functional reorganization of brain networks predicts motor outcome after stroke

      We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

      Abstract

      Background

      Dynamic functional connectivity (FC) studies have shown that motor recovery after stroke was associated with functional reorganization of brain networks. However, most previous studies have focused on interregional variability rather than the temporal variability (TV) of specific regions or networks. TV quantifies the dynamic reconfiguration of a region’s or network’s functional connectivity profile over time and reflects neural flexibility.

      Purpose

      This study investigated functional reorganization in chronic subcortical stroke using TV of brain networks derived from resting-state fMRI.

      Methods

      Thirty-three patients with left subcortical stroke (LSS), thirty with right subcortical stroke (RSS), and fifty-six age- and sex-matched healthy controls (HCs) were enrolled. Stroke patients underwent resting-state fMRI and Upper Extremity Fugl-Meyer Assessment (UE-FMA) at two time points. TV was computed to characterize dynamic functional connectivity at regional, intra-network, and inter-network levels. Group differences were assessed using one-way ANCOVA with post hoc tests. Linear regression was used to examine associations between TV and motor outcomes. The false discovery rate was used to multiple comparisons correction.

      Results

      Compared with HCs, both LSS and RSS showed significantly reduced TV in the right frontal-cingulate regions, the somatomotor hand network (SSH), and the connections between SSH and higher-order cognitive networks (all p < 0.05, |Cohen’s d| > 0.49). Increased TV was observed in the left postcentral gyrus, inferior frontal gyrus, cerebellar network (CEN), and somatomotor mouth network (all p < 0.05, |Cohen’s d| > 0.48). Relative to LSS, RSS exhibited additional TV reductions in the right middle occipital gyrus, orbital middle frontal gyrus, default mode network (DMN), and interactions among higher-order cognitive networks (all p < 0.05, |Cohen’s d| > 0.65). Notably, TV in the right opercular inferior frontal gyrus (IFGoperc) (β = 102.69, adjusted p = 6.4 × 10− 5) and CEN (β = 27.87, adjusted p = 0.011) at the first observation positively correlated with UE-FMA scores at follow-up, with effects modulated by lesion laterality.

      Conclusion

      TV captures multiscale functional reorganization in chronic subcortical stroke involving motor, cognitive, and sensory networks. TV of the right IFGoperc showed potential as a neuroimaging biomarker for predicting post-stroke motor recovery.

      Sunday, May 31, 2026

      Effortless Exercise Automatic Hand Trainer Gloves

       Have your competent? doctor validate that these are better than all these other ones out there. Can't do that? PURE INCOMPETENCE! I take no prisoners in getting stroke solved to 100% recovery. Aren't even trying to get there, then REMOVE THAT DEAD WOOD!

      Effortless Exercise Automatic Hand Trainer Gloves 

      So these gloves literally do hand rehabilitation exercises for you. You put them on, turn them on, and the built-in motors move each finger through a full range of motion automatically. No squeezing stress balls. No painful repetitive exercises you give up on after three days. The gloves do all the work while you sit there watching TV. This is a game changer for stroke recovery, arthritis, carpal tunnel, post surgery rehab, tendon injuries, or anyone dealing with hand stiffness and weakness. The biggest problem with hand therapy is that the people who need it most can't physically do the exercises on their own. These solve that completely. Multiple modes and intensity levels so you start gentle and increase as strength comes back over time. Rechargeable, portable, and quiet enough to wear anywhere. The kind of product that should be in every rehab center and every home where someone is recovering hand function. Genuinely surprised these aren't more mainstream yet. 💬 If you know someone recovering from a hand injury or stroke, send them this. Seriously. 🔗 Shop thousands of trending gadgets at Mavigadget.com 💰 Earn commissions — affiliate.mavigadget.com 🏪 Sell your products — partner.mavigadget.com hand trainer gloves, automatic hand exerciser, stroke recovery gloves, hand rehabilitation, arthritis gloves, finger therapy device, hand therapy gloves, grip recovery, carpal tunnel rehab, robotic rehab gloves, physical therapy hand, best stroke recovery tools #HandTrainer #StrokeRecovery #RehabGloves #Mavigadget #CoolGadgetsOpus 4.6 Extended

      Friday, May 22, 2026

      A 'Youthful' Brain May Boost Alzheimer's Resilience

       Ask your competent? doctor EXACTLY how to have a youthful brain! No knowledge, fire them and have them fired for incompetence! Dead wood needs to be removed unceremoniously! They do know exactly why Bernadette the nun was able to function quite well even with Alzheimers? NO? They incompetently know nothing about Bernadette? That's a game changer showing complete incompetence!

      A 'Youthful' Brain May Boost Alzheimer's Resilience

      Key Takeaways

      • Preserved global brain structure appeared to buffer cognitive decline in people with Alzheimer's pathology.
      • Younger-appearing brains had weaker links between pathology and poorer outcomes in multiple cognitive domains.
      • Other measures of brain reserve or cognitive reserve showed no clear protective cognitive effect.

      Greater structural brain integrity appeared to buffer the cognitive consequences of Alzheimer's disease pathology, cross-sectional data suggested.

      The study evaluated two markers of brain reserve -- brain-predicted age difference (brain-PAD) and a volumetric Alzheimer's disease signature -- in cognitively unimpaired older adults. Brain-PAD, a marker of overall structural brain health, uses MRI data to determine how much older or younger a brain appears relative to chronological age.

      Two markers of cognitive reserve, socioeconomic status and years of education, also were assessed.

      Brain-PAD moderated the association between Alzheimer's pathology and multiple cognitive domains, including episodic memory (β = -0.09), processing speed (β = -0.08), working memory (β = -0.10), and executive function/attentional control (β = -0.08), reported Kelsey Sewell, PhD, of Murdoch University School of Allied Health in Perth, Australia, and co-authors."Specifically, the negative association of greater Alzheimer's disease pathology with poorer cognition was weakest in individuals with younger-appearing brains," the researchers wrote in Neurology.

      A latent socioeconomic status score also appeared to influence the relationship between Alzheimer's pathology and episodic memory (β = 0.08), but the association did not remain significant after correction for multiple comparisons, Sewell and colleagues noted. Neither years of education nor the volumetric Alzheimer's signature moderated pathology-cognition associations, they added.

      "Our main finding was that maintaining good overall brain health may help reduce the impact of Alzheimer's‑related changes on cognitive function," Sewell said in a statement. "Things like exercise, maintaining a healthy diet, sleeping well, and finding new cognitive challenges can help to maintain a healthy brain."

      About 20% to 30% of adults ages 65 to 75 show evidence of Alzheimer's pathology despite having no measurable cognitive impairment, Sewell and co-authors said. "This phenomenon is often attributed to resilience, a general term describing multiple reserve-related processes that enable the brain to maintain higher levels of cognitive performance and function with aging or disease," they wrote."Within this framework, two key concepts are 'cognitive reserve' defined as a property of the brain that allows for cognitive performance better than expected given the degree of brain changes and pathology, and 'brain reserve' defined as the neurobiological capacity of the brain at a given point in time," they stated.

      The findings of this study support "the idea that preserved global brain structure reduces vulnerability to cognitive decline in the face of emerging pathology," noted Maria Carrigan, MSc, and Colin Groot, MSc, both of Amsterdam University Medical Center in the Netherlands, in an accompanying editorial.

      "For clinicians, the key message is that preserved global brain health seems to matter even before symptoms emerge," Carrigan and Groot wrote.

      "The study also raises important questions for future research," the editorialists added. "What biological processes underlie a younger-appearing brain? To what extent is brain-PAD modifiable through interventions targeting physical activity, vascular risk factors, or other lifestyle exposures? In addition, how does brain-PAD interact longitudinally with amyloid and tau accumulation to influence cognitive trajectories?"

      Sewell and colleagues examined whether cognitive and brain reserve modified the relationship between Alzheimer's pathology and cognition in 621 cognitively unimpaired, physically inactive participants in the IGNITE exercise trial in the U.S.

      Mean age was 70 years and 71% were women. The mean brain-PAD of the cohort was -4.05, indicating that participants' brains appeared younger than their chronological age, on average.

      Alzheimer's pathology was assessed using plasma phosphorylated tau (p-tau)-217. A subgroup of 355 participants also underwent tau PET imaging. Brain age was estimated from T1-weighted images.

      The researchers noted several limitations. The study was cross-sectional and could not determine causality: while accelerated brain aging might worsen the cognitive effects of Alzheimer's pathology, it's also possible that people with more advanced brain ages are more vulnerable to accumulating pathology.

      Emerging evidence suggests that p-tau217 may not be entirely specific to Alzheimer's pathology, they acknowledged. Findings from participants who had tau PET imaging supported the associations seen in the study.

      Judy George covers neurology and neuroscience news for MedPage Today, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more. Connect:
      Disclosures

      Sewell had no disclosures. One co-author disclosed being an inventor on a University of Pittsburgh patent regarding the IPMS assay for Aβ peptides and serving as a consultant for Quanterix.

      Carrigan and Groot had no relevant disclosures.

      Monday, May 18, 2026

      This Common Feeling May Be The Missing Piece In Mental Health by mindbodygreen

       The only way you can even get close to fixing this is for your competent? doctor to have EXACT 100% RECOVERY PROTOCOLS! Otherwise, your resilience has to be top of the world; mine is, which is why I'm joyful as hell.

      My  resilience story: I would still be leading a life of quiet desperation if still married.

      (Life is definitely better as I age, I got divorced enhancing my happiness immeasurably. I'm retired and comfortably well off. And healthy as I can be post stroke. I'm going to live a long time yet.)

      Your incompetent? doctor has known of this for almost a decade and done nothing, That should be fireable for cause! A hell of a lot of dead wood needs to be removed in stroke!

      This Common Feeling May Be The Missing Piece In Mental Health

      You've done the work. Maybe you started therapy, adjusted your medication, or finally addressed the stress that was running your life into the ground. The panic attacks have stopped. The heaviness has lifted. By most measures, you're better.

      So why does everything still feel so flat?

      If you've noticed that your anxiety or depression symptoms have improved but you still can't seem to feel excited, motivated, or genuinely happy, you're not imagining things. New research1 suggests that reducing negative emotions and restoring positive ones are two separate processes, and most mental health treatments only address half the equation.

      What is anhedonia (& why you might not realize you have it)

      Anhedonia is the clinical term for a diminished capacity to experience pleasure, interest, or motivation. Unlike sadness, which is an active emotional state, anhedonia is more like an absence: the things that used to light you up simply don't anymore.
      It's not that you feel bad, necessarily. It's that you don't feel much of anything.

      Anhedonia is increasingly recognized as a transdiagnostic feature, meaning it shows up across multiple conditions including depression, anxiety disorders, PTSD, and even burnout. Researchers describe it as encompassing "both motivational and affective deficits, including a reduced capacity to experience interest and pleasure in response to typically rewarding stimuli."

      Here's what anhedonia can look like in everyday life:

      Loss of anticipation: You used to look forward to weekends, vacations, or seeing friends. Now you feel neutral about things that should excite you.
      Motivation gaps: Starting projects, hobbies, or even simple tasks feels harder than it should, not because you're overwhelmed but because nothing feels worth the effort.
      Emotional flatness: Good news lands with a shrug. Compliments don't register. You're going through the motions without the emotional payoff.
      Social withdrawal: Not because you're anxious about seeing people, but because connection doesn't feel rewarding anymore.
      The tricky part is that anhedonia often flies under the radar. You might assume you're just tired, stressed, or "not a feelings person." But if joy, excitement, and motivation have quietly disappeared from your baseline, that's worth paying attention to.

      Why a reward-focused therapy outperformed traditional approaches

      The study tested a novel approach called Positive Affect Treatment (PAT), designed specifically to rebuild the brain's capacity for reward, not just reduce distress.
      Researchers recruited 98 adults with severely low positive affect and moderate-to-severe depression or anxiety. Participants were randomized to receive either PAT or Negative Affect Treatment (NAT), a comparison therapy focused on reducing threat responses through exposure, cognitive restructuring, and arousal reduction. Both groups completed 15 weekly individual therapy sessions.

      PAT produced greater overall clinical improvement than NAT, with benefits maintained at the one-month follow-up. The advantage was driven primarily by greater reductions in depression and anxiety symptoms in the PAT group.

      Notably, improvements in interviewer-rated anhedonia and self-reported positive affect did not differ between treatments, suggesting that both approaches can move the needle on these outcomes when they're explicitly measured.

      What makes PAT different is its focus on three distinct phases of reward processing:

      Reward anticipation-motivation: Learning to plan pleasurable activities and envision positive future experiences
      Reward consumption: Actively engaging in enjoyable activities and practicing savoring (vivid, present-focused attention to positive moments)
      Reward learning: Strengthening the connection between positive behaviors and improved mood, and taking credit for positive outcomes
      The researchers noted that "conventional pharmacological and psychological interventions have focused primarily on negative affect and demonstrate limited efficacy in achieving remission of anhedonia." In other words, standard treatments often leave this piece unaddressed.
      Negative & positive emotions run on separate tracks
      Here's the key insight from this research: negative emotions and positive emotions operate on different systems in the brain.

      Reducing anxiety, fear, or sadness doesn't automatically restore your ability to feel joy, motivation, or pleasure. These are separate processes regulated by distinct neural circuits.

      The study describes how reward processing is "centrally regulated by the mesocorticolimbic circuit," a network involving the prefrontal cortex, ventral striatum, and other regions that govern how we anticipate, experience, and learn from rewards.

      Think of it this way: turning down the volume on stress isn't the same as turning up the volume on joy. You can successfully quiet the alarm system in your brain and still have a reward system that's running on empty.

      This helps explain why so many people feel stuck in a gray zone after treatment. Their distress has decreased, but their capacity for positive experience hasn't been rebuilt.

      Seven ways to support your brain's reward system
      Research suggests reward sensitivity may be modifiable. Based on the strategies used in Positive Affect Treatment, here are evidence-backed ways to start supporting your capacity for positive emotions:

      Schedule pleasurable activities intentionally: Don't wait until you "feel like it." The PAT approach emphasizes planning enjoyable activities in advance, which helps rebuild the anticipation phase of reward processing. A walk outside, a favorite meal, or a call with someone who makes you laugh are all good starting points.
      Practice savoring: This means bringing full, present-focused attention to positive experiences while they're happening. Instead of rushing through a good moment or immediately moving to the next task, pause and notice what feels good. The study specifically highlights "vivid, present-focused mental rehearsal" as a core technique.
      Introduce novelty: New experiences activate reward circuits more strongly than familiar routines. This doesn't have to be dramatic: try a new recipe, take a different route, or explore a topic you've been curious about.
      Move your body: Physical activity has well-documented effects on mood and reward sensitivity. Even brief movement can shift your neurochemistry toward a more reward-responsive state.
      Prioritize social connection: The study mentions "loving-kindness and generosity" practices as part of PAT. Meaningful connection with others is one of the most reliable ways to activate positive affect. This might look like expressing gratitude, doing something kind for someone, or simply being present with people you care about.
      Take credit for positive outcomes: One subtle but powerful technique from PAT is self-attribution for good things that happen. Instead of dismissing positive experiences as luck or coincidence, practice acknowledging your role in creating them.
      Increase your joyspan: Research suggests that actively cultivating joy is a skill that can be developed over time, not just a personality trait you're born with.

      The takeaway

      Recovery isn't just about feeling less bad; it's about rebuilding your capacity to feel good. If you've been doing the work on your mental health but still feel emotionally flat, it may simply mean there's another dimension of healing that hasn't been addressed yet. Actively cultivating positive emotions, not just reducing negative ones, is essential for lasting well-being.

      Saturday, May 9, 2026

      AI-powered stroke tool linked to improved patient outcomes in large clinical trial

       Have your competent? doctor get the EXACT PROTOCOL! Not being able to do that simple task IS PURE INCOMPETENCE! I take no prisoners in trying to get stroke solved, which means a lot of dead wood/brains need to find easier jobs.  The gap is not stroke 'care' you blithering idiots, it's RECOVERY! The only goal in stroke is 100% recovery. And I think a lot of funerals will need to occur before we get the right strategy and leadership to GET THERE!

      Neils Bohr who famously said science progresses one funeral at a time.


      It is the same in stroke? How many and who will have to die before we get 100% recovery protocols?

      AI-powered stroke tool linked to improved patient outcomes in large clinical trial

      • A new study suggests that a stroke clinical decision support system (CDSS), which uses artificial intelligence (AI) assisted imaging, could help to significantly reduce the risk of recurrent vascular events.
      • Researchers suggest the AI tool is a safe intervention that provides the added benefits of lower cost and greater sustainability.
      • In the large study, the AI-based system improved stroke care(NOT RECOVERY!) and outcomes, supporting its potential as a scalable tool for routine stroke care(NOT RECOVERY!), particularly in resource-limited settings.

      Stroke is a significant global health concern and continues to be a leading cause of disability and death in the United States.

      Evidence suggests that more than 795,000 peopleTrusted Source in the U.S. have a stroke each year, and nearly one in four of those are people who have had a previous stroke.

      Clinicians play a critical role in preventing recurrent stroke. Typically, this occurs through implementing effective strategies, such as prevention plans, regular patient reviews, and addressing lifestyle modifications.

      To assist with this, clinicians may consider clinical decision support systems (CDSS). These systems can help healthcare institutions analyze data from electronic health records and make recommendations to physicians by sending prompts and reminders in real-time

      The potential scope of CDSS to help aid clinicians in complex decision-making processes for preventing stroke is increasing. However, many tools that utilize AI have not been rigorously evaluated, limiting their use.

      Now, a large study published in The BMJTrusted Source suggests an AI-powered CDSS may improve the quality of care(NOT RECOVERY!) and long-term outcomes for people who experience an acute ischemic stroke.

      The findings suggest that such systems could offer a scalable and cost-effective way to enhance stroke management, particularly in regions with limited healthcare resources.

      The use of AI technologies has increasingly been explored in healthcare, particularly for diagnosing disease, predicting outcomes, and supporting clinical decision making.

      However, many AI tools designed for stroke care(NOT RECOVERY!) have not yet undergone rigorous evaluation in real-world clinical settings, limiting their widespread adoption.

      To address this, researchers in China conducted a large trial to assess whether an AI-assisted CDSS could improve care(NOT RECOVERY!) quality and patient outcomes in routine practice.

      The system analyzes brain scans to classify stroke causes and combines this with evidence-based treatment recommendations tailored to individual patients.

      The research team suggests that the AI-based tool was associated with a significant reduction in subsequent vascular events compared with standard care(NOT RECOVERY!).

      Christopher Yi, MD, board certified vascular surgeon at MemorialCare Orange Coast Medical Center in Fountain Valley, CA, who was not involved in the study, suggests how AI could fit into stroke management.

      “This study is the first of its kind to utilize AI for stroke care(NOT RECOVERY!) from being a diagnostic aid to being a tool that can improve care(NOT RECOVERY!) quality and reduce recurrent vascular events,” said Yi.

      “In this study, the CDSS did more than read images: It integrated AI-assisted imaging, stroke-cause classification, reminders for needed evaluations, and guideline-based treatment recommendations,” he added.

      “The biggest takeaway is that a well-integrated CDSS can help clinicians deliver more consistent evidence-based stroke care. It also helps guide interventionalists to better outcomes by improving stroke care quality and decreasing long term vascular events.”
      – Christopher Yi, MD

      The large study involved more than 21,000 participants with acute ischemic stroke admitted to 77 hospitals across China within 7 days of symptom onset. The individuals had an average age of 67, and just over one-third were female.

      Between January 2021 and June 2023, 11,054 people received treatment at 38 hospitals supported by the AI-based CDSS. The other 10,549 participants at 39 hospitals received usual medical care.

      Physicians in the intervention group were trained to use the system. The CDSS incorporated a range of patient-specific factors, including age, medical history, lifestyle, and hospital characteristics, when generating recommendations.