Summary: Researchers revealed that certain
personality traits, such as conscientiousness, extraversion, and
positive affect, can reduce the likelihood of a dementia diagnosis.
This
comprehensive analysis involved over 44,000 people, with 1,703
developing dementia. Surprisingly, the researchers found no correlation
between these protective personality traits and brain pathology in
deceased individuals, suggesting these traits may enhance resilience to
dementia-related impairments.
This study highlights the potential
of targeting personality traits in interventions to lower long-term
dementia risk, emphasizing the role of non-genetic factors in dementia
development.
Key Facts:
- Positive personality traits like conscientiousness and extraversion are linked to a lower dementia risk.
- The study analyzed data from over 44,000 individuals, providing a broad perspective on the issue.
- No direct link was found between these personality traits and brain pathology, suggesting a resilience mechanism at play.
Source: UC Davis
People
with personality traits such as conscientiousness, extraversion and
positive affect are less likely to be diagnosed with dementia than those
with neuroticism and negative affect, according to a new analysis by
researchers at the University of California, Davis and Northwestern
University.
The difference was not linked to physical
damage to brain tissue found in dementia patients, but more likely to
how certain personality traits help people navigate dementia-related
impairments.
The work is published Nov. 29 in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
Previous
studies have tried to establish links between personality traits and
dementia, but these were mostly small and represented only specific
populations, said Emorie Beck, assistant professor of psychology at UC
Davis and first author on the paper.
“We wanted to leverage new technology to synthesize these studies and
test the strength and consistency of these associations,” Beck said. If
those links hold up, then targeting personality traits for change in
interventions earlier in life could be a way to reduce dementia risk in
the long term, she said.
Beck and colleagues analyzed data from
eight published studies including over 44,000 people, of whom 1,703
developed dementia. They looked at measures of the “big five”
personality traits (conscientiousness, extraversion, openness to
experience, neuroticism and agreeableness) and subjective wellbeing
(positive and negative affect, and life satisfaction) compared to
clinical symptoms of dementia (performance on cognitive tests) and brain
pathology at autopsy.
Personality is typically thought to be
linked to dementia risk through behavior, Beck said. For example, people
who score high on conscientiousness may be more likely to eat well and
take care of their health, which results in better health in the long
term.
The researchers found that high scores on negative traits
(neuroticism, negative affect) and low scores on positive traits
(conscientiousness, extraversion, positive affect) were associated with a
higher risk of a dementia diagnosis. High scores on openness to
experience, agreeableness, and life satisfaction had a protective effect
in a smaller subset of studies.
Link to diagnosis but not pathology
To
their surprise, however, no link was found between these personality
traits and actual neuropathology in the brains of people after death.
“This
was the most surprising finding to us,” Beck said. “If personality is
predictive of performance on cognitive tests but not pathology, what
might be happening?”
One
explanation is that some personality traits could make people more
resilient to the damage caused by diseases such as Alzheimer’s.
People with higher levels of some traits may find ways, whether they
are aware of it or not, to cope with and work around impairments. Other
work by members of the study team has shown that some people with quite
extensive pathology can show little impairment on cognitive tests.
The
researchers also looked at other factors that could moderate the
relationship between personality and dementia risk and neuropathology,
including age, gender and educational attainment.
“We found almost no evidence for effects, except that conscientiousness’s protective effect increased with age,” Beck said.
Many
factors contribute to the development of dementia. Among those that
aren’t directly related to genetics, this study is a first step in
teasing out the associations between personality and dementia, Beck
said.
The researchers plan to continue and expand the work,
including looking at people who show little impairment in the face of a
lot of pathology. They also hope to look at other everyday factors that
might play a role in developing dementia.
Part of the work was
conducted while Beck was a postdoctoral researcher at Northwestern
University in Chicago. Coauthors are: Tomiko Yoneda, UC Davis and
Northwestern; Daniel Mroczek and Eileen Graham, Northwestern; Bryan
James, David Bennett and John Morris, Rush University Medical Center,
Chicago; Jason Hassenstab, Washington University School of Medicine, St.
Louis; Mindy Katz and Richard Lipton, Albert Einstein College of
Medicine, the Bronx.
Funding: The work was supported by grants from the National Institute on Aging.
About this personality and dementia research news
Author: Andrew Fell
Source: UC Davis
Contact: Andrew Fell – UC Davis
Image: The image is credited to Neuroscience News