Beet Juice May Lower Blood Pressure in Older Adults Within Two Weeks: Study

 

Your competent? doctor started prescribing this 9 years ago to keep your brain young, right? NO? SO, INCOMPETENCE REIGNED!

This Natural Juice Helps Keep Your Brain Young - Beetroot juice April 2017

I actually found beet juice once and tried it, never again. Even diluting it 9 to 1 with cranberry juice it was undrinkable. 

Beet Juice May Lower Blood Pressure in Older Adults Within Two Weeks: Study

Beetroot juice lowers blood pressure in older people by changing oral microbiome, suggests study

 Your competent? doctor started prescribing this 8 years ago to keep your brain young, right? NO? SO, INCOMPETENCE REIGNED!

This Natural Juice Helps Keep Your Brain Young - Beetroot juice April 2017

I actually found beet juice once and tried it, never again. Even diluting it 9 to 1 with cranberry juice it was undrinkable. 

The latest here:

Beetroot juice lowers blood pressure in older people by changing oral microbiome, suggests study

Study suggests that vitamin C and dietary nitrate could be promising in improving endothelial function and reducing cardiovascular disease risk

Does your doctor competently have diet protocols for all the research out there on diet health?  WELL, IS YOUR DOCTOR INCOMPETENT OR NOT?  NO protocol, definitely incompetent! Guidelines or handouts don't count.

 

The foods highest in nitrate include beet roots and leafy greens such kale, arugula, chard, and spinach. Others include parsley, Chinese cabbage, leeks, celery, radishes, and turnips.

Study suggests that vitamin C and dietary nitrate could be promising in improving endothelial function and reducing cardiovascular disease risk

By Tarun Sai LomteMay 12 2023Reviewed by Lily Ramsey, LLM

A recent study published in the Nutrition Journal discussed the role of vitamin C and dietary nitrate in endothelial function (EF).

Study: Is vitamin C a booster of the effects of dietary nitrate on endothelial function? Physiologic rationale and implications for research. Image Credit: Tatjana Baibakova/Shutterstock.com

Background

A central feature of cardiovascular disease (CVD) is the disruption of the endothelial lining, identified as endothelial dysfunction (ED). ED represents an early marker of vascular damage and an essential step in the pathogenesis of atherosclerosis.

Endothelial cells secrete nitric oxide (NO) among other molecules and participate in inflammatory responses.

The availability of vasodilators, especially NO, is reduced in ED. Consequently, the integrity of blood vessels is disrupted, promoting the development or progression of chronic diseases like CVD.

Given the potential reversibility of ED, an early implementation of interventions could offer prophylactic and therapeutic benefits for patients with or at risk of CVD.

Interventions such as dietary nitrate, vitamin C, arginine, or polyphenols, aimed to augment NO bioavailability could positively affect EF and CVD pathogenesis.

In the present study, the authors discussed the putative mechanisms of the synergistic effect of dietary nitrate and vitamin C on EF.

Dietary nitrate and endothelial function

NO rapidly diffuses across tissues reaching target cells and exerting biological effects. It is auto-oxidized to nitrate or nitrite in circulation by oxyhemoglobin.

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Therefore, nitrate and nitrite act as stable end products and may indirectly reflect systemic levels of NO. On average, nitrate intake following the Western diet is around 110 mg/day.

Nitrate is rapidly and efficiently absorbed, and plasma concentrations peak within 90 to 120 minutes. A high dietary nitrate intake has positively affected metabolic, immune, and vascular functions. Several studies have assessed the impact of dietary nitrate or nitrite on EF in humans and animals.

One study observed a significant improvement in ED with dietary nitrate supplementation in a murine hypercholesterolemia model. Studies report contrasting findings in humans supplemented with nitrate.

For example, dietary nitrate consumption did not affect flow-mediated dilation (FMD) in obese/overweight individuals. Likewise, EF was not improved with two-week beetroot consumption in those with type 2 diabetes.

By contrast, one study observed positive effects on FMD with a single dose of nitrate in young, healthy participants. Similarly, another study reported FMD improvements in individuals with hypercholesterolemia after a six-week intervention of high-nitrate beetroot juice.

A systematic review and meta-analysis concluded that supplementation of inorganic nitrate and beetroot was linked to beneficial effects on EF.

Endothelial function and vitamin C

The benefits of vitamin C intake on EF may be due to the increased NO bioavailability. A systematic review reported a significant improvement in EF with vitamin C supplementation, with varying effects by health condition.

Vitamin C enhanced FMD and reduced serum levels of an oxidative stress biomarker in metabolic syndrome patients.

A study examining the effects of vitamin C on oxygen delivery in individuals with mild or moderate chronic heart failure observed an improvement in pulse wave velocity after vitamin C treatment.

Intravenous administration of high vitamin C doses was found to reverse the effects of free fatty acids on forearm blood flow (FBF).

Synergistic effects of vitamin C and dietary nitrate on endothelial function

Evidence strongly suggests that increased bioavailability of NO may improve EF and influence. Recent studies shed light on the potential interactive and positive effects of inorganic nitrate and vitamin C co-supplementation on blood pressure and EF, suggesting their synergistic effects could far exceed their potencies.

A combined dose of inorganic nitrate and vitamin C significantly decreased arterial stiffness in adult and older subjects and reduced systolic blood pressure (BP) and mean arterial BP in older individuals. Two independent studies have confirmed these findings, which observed EF improvements in older hypertensive individuals and people with ED, respectively.

The vasodilatory effect of nitrite was enhanced in an acidic solution in an in vitro rat aorta model, which was further enhanced by adding vitamin C.

Furthermore, animal and in vitro studies showed that inorganic nitrate and vitamin C may improve tetrahydrobiopterin (BH₄) stability. When BH₄ is depleted, superoxide free radicals are formed instead of NO. Vitamin C can scavenge ROS, particularly superoxide, by activating superoxide dismutase (SOD).

Concluding remarks

In sum, co-supplementing dietary nitrate with vitamin C could enhance NO synthesis and nitrite-to-NO conversion and improve EF. Preliminary evidence suggests their synergistic effects could be more potent than individual effects.

Further studies are required to assess the impact of the co-supplementation of the two compounds on vascular outcomes in larger cohorts and test whether population genetic or phenotypic characteristics influence their synergistic effects.

Journal reference:

• Lbban, E. et al. (2023) "Is vitamin C a booster of the effects of dietary nitrate on endothelial function? Physiologic rationale and implications for research", Nutrition, 109, p. 111995. doi: 10.1016/j.nut.2023.111995. https://www.sciencedirect.com/science/article/pii/S0899900723000254

Can Beet Juice Really Boost Your Physical Fitness? We Asked an RD

I do pickled beets and have been ever since this came out:

Beet Juice Beats Hypertension April 2013 

But I don't know the amount I should be doing, THAT  is what stroke leadership should have researchers find out. But we have NO STROKE LEADERSHIP,  so you're screwed. 

Except for this possible problem;

Beet juice can lower blood pressure — sometimes too much April 2017 

I actually found beet juice once and tried it, never again. Even diluting it 9 to 1 with cranberry juice it was undrinkable.

 

What the hell is your doctor doing the first week to improve blood flow to your brain? NOTHING? Then you need to have him/her fired along with the stroke president AND the board of directors.  I take no prisoners. There is NO EXCUSE FOR SUCH INCOMPETENCE. 

Can Beet Juice Really Boost Your Physical Fitness? We Asked an RD

Betty Gold

Real SimpleApril 27, 2020, 12:50 PM EDT

We’re well aware that beets are part of a nutritious diet, but beet root juice touts one of the biggest health halos among trendy superfoods today. The drink has formed a cult following of folks who believe it will improve their athletic performance, fight inflammation, and provide extra energy when working out. How much of beet juice’s superfood status is actual science and how much can be filed as just another form of overhyped snake oil? We consulted Kelli McGrane, RD, a nutritionist for the food tracking app Lose It!, for the real-deal health benefits of beetroot juice.
RELATED: The 30 Healthiest Foods to Eat Every Day

Rich in Vitamins and Minerals

“Beet root juice is a rich source of several essential minerals, including iron, folate, magnesium, calcium, zinc, and vitamin B6,” says McGrane. It’s also a solid source of vitamin C, which helps boost your immune system and defend your cells against damage from free radicals. Vitamin C also supports collagen production and helps your body absorb iron.

Antioxidants and Anti-Inflammatory Benefits

Part of what makes beetroot juice so nutritious is its high amount of water-soluble compounds called betalains. “These are what’s responsible for beet root's red color,” explains McGrane. “But in addition to being a pigment, betalains have been found to have potent antioxidant and anti-inflammatory effects.” One study published in the journal Critical Reviews in Food Science and Nutrition showed that betalaines actually have chemo-preventive abilities against some cancer cell lines, thanks to their antioxidant characteristics and ability to destroy unstable cells in the body.
RELATED: Red Alert: These Are the 4 Worst Foods That Cause Inflammation

Improved Physical Fitness

According to McGrane, this has some legitimacy. “Due to its concentration of nitrates and betalains, drinking beetroot juice has been linked with improving athletic performance and reducing muscle fatigue by helping to improve blood flow and oxygen delivery to the muscles.” A 2019 study found that cyclists who consumed beet juice for one week showed improved performance—and actually finished a 10k course 1.6 percent faster in both low- and high-altitude conditions—compared to those who went without the beet juice. The researchers credit their improved physical fitness to the high levels of nitrates in beet juice. This gets converted into nitric oxide in the body, which improves circulation, dilates and relaxes blood vessels, and increases oxygen in the blood.

Reduced Blood Pressure

One study published in the journal Hypertension showed that those who drank beet juice—versus those who drank water—saw a drop in blood pressure and less blood clotting after a three hour period. Another study showed that those who drank a 16-ounce glass of beet juice actually lowered their systolic blood pressure by an average of four to five points. “This is due to beet juice’s ability to improve blood flow, which may help lower blood pressure levels,” explains McGrane. Research published in the journal Circulation also found a connection between beet juice and a 13 percent increase in muscle power in those who had experienced heart failure—again, thanks to its high amount of nitrates.

Potassium

Beetroot juice is rich in the mineral potassium, an electrolyte that helps muscles and nerves function, and helps stave off muscle cramps, fatigue, and weakness. Potassium also helps offset some of the heart-damaging effects of sodium.
Bottom line: It certainly isn’t snake oil. Beetroot juice is packed with vitamins, minerals, and powerful antioxidants. That being said, we—and the entire nutrition community—are strong proponents of eating fresh, whole fruits and vegetables over juicing them. When you opt for beet juice over whole beets, you’re consuming a ton of extra sugar and slashing all of the fiber content that occurs naturally in root vegetables. This also means you’re less likely to feel full or remotely satisfied after drinking (versus eating) your beets and will feel your blood sugar spike instead. Simple solution: pack all of the above health benefits into your diet by making one of Real Simple’s best beet recipes—your absence of juice-induced hanger will speak for itself.
RELATED: Everything You Need to Know About Cooking Beets

Dark chocolate improves coronary vasomotion and reduces platelet reactivity

What is your doctor doing IMMEDIATELY post stroke to increase oxygen to your brain? Maybe this dark chocolate  by dilating your arteries?

Or your doctor will never suggest this one:

 The team that found chronic cannabis users have higher cerebral blood flow and extract more oxygen from brain blood flow than nonusers.

 Or maybe beet juice?

 The study showed that beet juice with high amounts of nitrate made the blood vessels relax and return to normal function

Or this?

Sesquiterpenes, a natural compound found in essential oils of Vetiver, Patchouli, Cedarwood, Sandalwood and Frankincense, can increase levels of oxygen in the brain by up to 28 percent 

There is this from March, 2005:

A Pilot Study of Normobaric Oxygen Therapy in Acute Ischemic Stroke

 And this in October, 2010

Normobaric oxygen therapy in acute ischemic stroke: A pilot study in Indian patients

And this from October 2012:

Normobaric Oxygen Therapy

If your doctor is doing nothing about oxygen delivery to the brain s/he is letting more neurons die than should. ARE YOU OK WITH THAT?

The latest here:

Dark chocolate improves coronary vasomotion and reduces platelet reactivity

Flammer AJ¹, Hermann F, Sudano I, Spieker L, Hermann M, Cooper KA, Serafini M, Lüscher TF, Ruschitzka F, Noll G, Corti R.

Author information

1

Cardiovascular Center, Cardiology, University Hospital Zurich, Raemistr 100, CH-8091 Zurich, Switzerland.

Abstract

BACKGROUND:

Dark chocolate has potent antioxidant properties. Coronary atherosclerosis is promoted by impaired endothelial function and increased platelet activation. Traditional risk factors, high oxidative stress, and reduced antioxidant defenses play a crucial role in the pathogenesis of atherosclerosis, particularly in transplanted hearts. Thus, flavonoid-rich dark chocolate holds the potential to have a beneficial impact on graft atherosclerosis.

METHODS AND RESULTS:

We assessed the effect of flavonoid-rich dark chocolate compared with cocoa-free control chocolate on coronary vascular and platelet function in 22 heart transplant recipients in a double-blind, randomized study. Coronary vasomotion was assessed with quantitative coronary angiography and cold pressor testing before and 2 hours after ingestion of 40 g of dark (70% cocoa) chocolate or control chocolate, respectively. Two hours after ingestion of flavonoid-rich dark chocolate, coronary artery diameter was increased significantly (from 2.36+/-0.51 to 2.51+/-0.59 mm, P<0.01), whereas it remained unchanged after control chocolate. Endothelium-dependent coronary vasomotion improved significantly after dark chocolate (4.5+/-11.4% versus -4.3+/-11.7% in the placebo group, P=0.01). Platelet adhesion decreased from 4.9+/-1.1% to 3.8+/-0.8% (P=0.04) in the dark chocolate group but remained unchanged in the control group.

CONCLUSIONS:

Dark chocolate induces coronary vasodilation, improves coronary vascular function, and decreases platelet adhesion 2 hours after consumption. These immediate beneficial effects were paralleled by a significant reduction of serum oxidative stress and were positively correlated with changes in serum epicatechin concentration.

Comment in

• Is it the dark in dark chocolate? [Circulation. 2007]

PMID:

17984375

DOI:

10.1161/CIRCULATIONAHA.107.713867

Effects of Montmorency tart cherry (Prunus Cerasus L.) consumption on vascular function in men with early hypertension

Well has your doctor prescribed this from 3 years ago or beet juice from 6 years ago? 

Beet Juice Beats Hypertension April 2013

Except for this possible problem;

Beet juice can lower blood pressure — sometimes too much April 2017 

Or did your doctor immediately prescribe pills?  I'm not medically trained so you can't listen to me.  Has your doctor read any research since medical school?

Effects of Montmorency tart cherry (Prunus Cerasus L.) consumption on vascular function in men with early hypertension

Karen M Keane, Trevor W George, Costas L Constantinou, Meghan A Brown, Tom Clifford, Glyn Howatson

The American Journal of Clinical Nutrition, Volume 103, Issue 6, June 2016, Pages 1531–1539, https://doi.org/10.3945/ajcn.115.123869

Published:

04 May 2016

Article history

ABSTRACT

Background: Tart cherries contain numerous polyphenolic compounds that could potentially improve endothelial function and reduce cardiovascular disease risk.
Objective: We sought to examine the acute effects of Montmorency tart cherry (MC) juice on vascular function in subjects with early hypertension.
Design: A placebo-controlled, blinded, crossover, randomized Latin square design study with a washout period of ≥14 d was conducted. Fifteen men with early hypertension [systolic blood pressure (SBP) ≥130 mm Hg, diastolic blood pressure ≥80 mm Hg, or both] received either a 60-mL dose of MC concentrate or placebo. Microvascular reactivity (laser Doppler imaging with iontophoresis), arterial stiffness (pulse wave velocity and analysis), blood pressure, and phenolic acid absorption were assessed at baseline and at 1, 2, 3, 5, and 8 h postconsumption.
Results: MC consumption significantly lowered SBP (P < 0.05) over a period of 3 h, with peak reductions of mean ± SEM 7 ± 3 mm Hg 2 h after MC consumption relative to the placebo. Improvements in cardiovascular disease risk factors were closely linked to increases in circulating protocatechuic and vanillic acid at 1–2 h.
Conclusions: MC intake acutely reduces SBP in men with early hypertension. These benefits may be mechanistically linked to the actions of circulating phenolic acids. This study provides information on a new application of MCs in health maintenance, particularly in positively modulating SBP. This trial was registered at clinicaltrials.gov as NCT02234648.

Beet juice

Finally found a bottle of this in my local grocery store. Even though it has 10% apple juice added it is not drinkable. I get it down by 1 part beet juice to 6 parts cranberry/pomegranate juice.  Talk to your doctor, I know nothing. I'm sticking with pickled beets.
For this reason:

Beet Juice Beats Hypertension April 2013

Except for this possible problem;

Beet juice can lower blood pressure — sometimes too much April 2017

 

Absence of an effect of high nitrate intake from beetroot juice on blood pressure in treated hypertensive individuals: a randomized controlled trial

Ok, a one week trial with beetroot juice doesn't reduce blood pressure. The simple next question which will never be answered; What time period of beetroot intervention is needed to reduce blood pressure? Don't you ever follow questions to their conclusion?
Almost 3 years old and I bet there has been NO followup.
It seems NO ONE CARES about solving anything that might help stroke survivors.
Our fucking failures of stroke associations don't care. Your doctor doesn't care. Your stroke hospital doesn't care.
https://www.mdlinx.com/internal-medicine/medical-news-article/2015/07/03/beetroot-blood-pressure-nitrate-nitric-oxide/6218974/?

American Journal of Clinical Nutrition — | July 03, 2015

Bondonno CP, et al. – In this study, the authors assessed whether increased dietary nitrate intake by using beetroot juice for 1 wk lowers blood pressure in treated hypertensive men and women. An increase in dietary nitrate intake may not be an effective short–term approach to further lower blood pressure in treated hypertensive subjects.

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Methods

• Participants (n = 27) were recruited to a randomized, placebo-controlled, double-blind crossover trial. The effect of 1-wk intake of nitrate-rich beetroot juice was compared with 1-wk intake of nitrate-depleted beetroot juice (placebo).
• The primary outcome was blood pressure assessed by measuring home blood pressure during the intervention and 24-h ambulatory blood pressure on day 7 of the intervention.
• Other outcomes included nitrate metabolism assessed by measuring nitrate and nitrite in plasma, saliva, and urine.

Results

• Relative to the placebo, 1-wk intake of nitrate-rich beetroot juice resulted in a 3-fold increase in plasma nitrite and nitrate, a 7-fold increase in salivary nitrite, an 8-fold higher salivary nitrate, and a 4-fold increase in both urinary nitrite and nitrate (P < 0.001).
• However, no differences in home blood pressure and 24-h ambulatory blood pressure were observed with 1-wk intake of nitrate-rich beetroot juice in comparison with the placebo.

Read the full article on American Journal of Clinical Nutrition

The Nitrate-Independent Blood Pressure–Lowering Effect of Beetroot Juice: A Systematic Review and Meta-Analysis

And just when are you going to be getting beetroot juice in the hospital or in a prescription from your doctor?
https://academic.oup.com/advances/article/8/6/830/4772205?rss=1

Zahra Bahadoran Parvin Mirmiran Ali Kabir Fereidoun Azizi Asghar Ghasemi

Advances in Nutrition, Volume 8, Issue 6, 1 November 2017, Pages 830–838, https://doi.org/10.3945/an.117.016717

Published:

07 November 2017

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Abstract

Beetroot is considered a complementary treatment for hypertension because of its high content of inorganic NO₃. This systematic review and meta-analysis aimed to clarify several aspects of beetroot juice supplementation on systolic blood pressure (SBP) and diastolic blood pressure (DBP). We searched PubMed, Scopus, and Embase databases, and the reference lists of previous reviews. Randomized clinical trials that investigated the effects of beetroot juice on resting blood pressure in humans were recruited for quality assessment, meta-analyses, subgroup analyses, and meta-regressions; of these, 22 were conducted between 2009 and 2017 and included a total of 47 intervention (n = 650) and 43 control (n = 598) groups. Overall, SBP (−3.55 mm Hg; 95% CI: −4.55, −2.54 mm Hg) and DBP (−1.32 mm Hg; 95% CI: −1.97, −0.68 mm Hg) were significantly lower in the beetroot juice–supplemented groups than in the control groups. The mean difference of SBP was larger between beetroot juice–supplemented and control groups in the longer than in the shorter (≥14 compared with <14 d) study durations (−5.11 compared with −2.67 mm Hg) and the highest compared with the lowest (500 compared with 70 and 140 mL/d) doses of beetroot juice (−4.78 compared with −2.37 mm Hg). A positive correlation was observed between beetroot juice doses and the mean differences of blood pressures. In contrast, a smaller effect size of blood pressures was observed after supplementation with higher NO₃ (milligrams per 100 mL beetroot juice). A weak effect size was observed in a meta-analysis of trials that used NO₃-depleted beetroot juice as a placebo compared with other interventions (−3.09 compared with −4.51 mm Hg for SBP and −0.81 compared with −2.01 mm Hg for DBP). Our results demonstrate the blood pressure–lowering effects of beetroot juice and highlight its potential NO₃-independent effects.

Effect of Probiotics on Blood Pressure

Nothing will occur about your doctor prescribing food for blood pressure reduction, Big Pharma is in charge. You can't do this on your own, that would be dangerous with your doctor not knowing about it. Followup is needed to have amounts needed per body weight.Or maybe you want to talk to your doctor about this:

Beet Juice Beats Hypertension April 2013

Except for this possible problem;

Beet juice can lower blood pressure — sometimes too much April 2017

The latest here:

Effect of Probiotics on Blood Pressure

A Systematic Review and Meta-Analysis of Randomized, Controlled Trials

Saman Khalesi, Jing Sun, Nicholas Buys, Rohan Jayasinghe

Download PDF

https://doi.org/10.1161/HYPERTENSIONAHA.114.03469

Hypertension. 2014;64:897-903

Originally published July 21, 2014

Abstract

Previous human clinical trials have shown that probiotic consumption may improve blood pressure (BP) control. The aim of the present systematic review was to clarify the effects of probiotics on BP using a meta-analysis of randomized, controlled trials. PubMed, Scopus, Cochrane Library (Central), Physiotherapy Evidence Database, and Clinicaltrial.gov databases were searched until January 2014 to identify eligible articles. Meta-analysis using a random-effects model was chosen to analyze the impact of combined trials. Nine trials were included. Probiotic consumption significantly changed systolic BP by −3.56 mm Hg (95% confidence interval, −6.46 to −0.66) and diastolic BP by −2.38 mm Hg (95% confidence interval, −2.38 to −0.93) compared with control groups. A greater reduction was found with multiple as compared with single species of probiotics, for both systolic and diastolic BP. Subgroup analysis of trials with baseline BP ≥130/85 mm Hg compared with <130/85 mm Hg found a more significant improvement in diastolic BP. Duration of intervention <8 weeks did not result in a significant reduction in systolic or diastolic BP. Furthermore, subgroup analysis of trials with daily dose of probiotics <10¹¹ colony-forming units did not result in a significant meta-analysis effect. The present meta-analysis suggests that consuming probiotics may improve BP by a modest degree, with a potentially greater effect when baseline BP is elevated, multiple species of probiotics are consumed, the duration of intervention is ≥8 weeks, or daily consumption dose is ≥10¹¹ colony-forming units.

More at link.

Beetroot juice may provide benefits to heart disease patients

I'm doing about 3-4 oz. of pickled beets daily but have no clue how much good it is doing. You might be able to add this to your diet stroke protocol in a couple hundred years.
https://www.mdlinx.com/family-medicine/medical-news-article/2017/05/11/beetroot-juice-sympathetic-nerve-activity-heart-disease/7169795/?

American Physiological Society News

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Nitrate supplementation decreases sympathetic nerve responses that contribute to disease risk.
A new study finds that dietary nitrate – a compound that dilates blood vessels to decrease blood pressure – may reduce overstimulation of the sympathetic nervous system that occurs with heart disease. The research team looked specifically at beetroot juice, a source of dietary nitrate, to explore its use as a future targeted treatment option for people with cardiovascular disease. The study is the first to study the effects of nitrate supplementation on sympathetic nerve activity.

Activation of the sympathetic nervous system results in elevated heart rate and blood pressure and blood vessel constriction. Sympathetic outflow also increases with some forms of cardiovascular disease, including high blood pressure and heart failure. The aim of the study was to show that “acute nitrate supplementation using beetroot juice can decrease muscle sympathetic outflow at rest and during exercise,” the Canadian research team wrote.

Twenty young adult volunteers (average age: 27) participated in two separate testing visits in which they blindly received either a nitrate supplement or a placebo. On both visits, the research team recorded the blood pressure, heart rate and muscle sympathetic nerve activity (MSNA) and measured muscle activity at rest and during handgrip exercise with the participants’ non–dominant hand. Measurements were recorded at the beginning of the visit and then again after the volunteers drank nitrate–rich beetroot juice or a placebo and had rested on their backs for three hours.

MSNA burst rate, denoting the frequency of nerve activity, was lower when the volunteers drank beetroot juice compared to when they drank the placebo. Sympathetic nerve activity also decreased during exercise. “Surprisingly, no differences in blood pressure were detected at rest or during exercise,” the research team noted. “These results provide proof–of–concept that dietary nitrate supplementation can modulate central sympathetic outflow and suggest that the established cardiovascular benefits of dietary nitrate are likely to involve a neural contribution.”

The article, “Acute beetroot juice supplementation on sympathetic nerve activity: A randomized, double–blind, placebo–controlled proof–of–concept study,” was published ahead of print in the American Journal of Physiology–Heart and Circulatory Physiology.

This Natural Juice Helps Keep Your Brain Young - Beetroot juice

You'll have to guess what amount to take because your doctor will know absolutely nothing about this. I go for pickled beets instead. Maybe about 3 oz. each evening, no clue if it is doing any good.
This sounds like it might be incredibly important immediately post-stroke. 
http://www.spring.org.uk/2017/04/beetroot-juice.php?omhide=true

Older brains can perform like younger ones with this supplement.

A beetroot juice supplement can make older brains perform like younger ones, new research shows.
The supplement was given to older adults just before they worked out.
Professor Jack Rejeski, a study co-author, said:

“We knew, going in, that a number of studies had shown that exercise has positive effects on the brain.
But what we showed in this brief training study of hypertensive older adults was that, as compared to exercise alone, adding a beet root juice supplement to exercise resulted in brain connectivity that closely resembles what you see in younger adults.”

People in the study were over 55, did not exercise and had high blood pressure.
They were given the beetroot supplement an hour before a moderate intensity 50-minute treadmill workout.
The critical ingredient in beetroot is nitrate, which is converted to nitric oxide in the body.
Nitric oxide helps increase blood flow.
Professor Rejeski said:

“Nitric oxide is a really powerful molecule.
It goes to the areas of the body which are hypoxic, or needing oxygen, and the brain is a heavy feeder of oxygen in your body.”

The exercise plus the beets help to deliver more oxygen to the brain, helping to give a boost beyond your years.

The study was published in Journals of Gerontology: Medical Sciences (Petrie et al., 2017).

Beet juice can lower blood pressure — sometimes too much

This wouldn't be a problem if we had a protocol on amounts to use per bodyweight and sex to keep the proper amount of nutrients circulating in our bloodstream.

Beet juice can lower blood pressure — sometimes too much

A glass of beet juice has been found to lower systolic blood pressure more than some anti-hypertensive medications, write Joe and Teresa Graedon.

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Q: I read that beet juice is good for your health and heart. I have high blood pressure and take losartan and metoprolol to control it. I also had three stents inserted in my arteries almost four years ago.
I started to drink small amounts of beet juice in February. Within two days I had episodes of lightheadedness, vertigo and nausea.
That might have been the result of food poisoning, so I held off drinking more beet juice for several weeks. Three days ago I drank a bit more, and again I had episodes of lightheadedness after a couple of hours.
Is there any possible relation to beet juice?

3-course dinners for $32 starting April 2.

A: Adding beet juice to medications like losartan and metoprolol might have lowered your blood pressure too much. Symptoms of low blood pressure include lightheadedness, dizziness, feeling faint and nausea.
One study discovered that a glass of beet juice lowered systolic blood pressure by over 8 points (Hypertension, February 2015). That’s more than some anti-hypertensive medications.
We would encourage you to measure your blood pressure at home. If it is under good control with the medications you are taking, your doctor may advise you to avoid beet juice.

Proof That Intense Cardio May Help You Live Longer

If you don't think you can do this try this. Why didn't your doctor tell you about this?

Want to Exercise Harder? Try Drinking Beet Juice

Proof That Intense Cardio May Help You Live Longer

If you knew that simply adding more cardio to your life would help you live longer, would you work out more?

A new study published in Science Advances shows that that exercise endurance (a sexy term for intense cardio that increases your breathing and heart rate) may help keep our telemores(sic) in tact. Telemores(sic) are the protective “caps” on the ends of our DNA chromosomes which keep us young.

And just to underscore this study’s significance, as we age — and with added effects of stress and disease — our telemores(sic) structures start to break down. So, finding ways to keep our telemores(sic)long and strong give us a better chance of living a longer life.

To prove that exercise could add on years to our life, a research team had ten healthy and young volunteers cycle for 45 minutes. They found that the amount of telomere transcripts (which control telemores)(sic) increased in volunteers post-workout.

The experiment results also support recent theories that exercise and diet (another potential influence on telemores)(sic) could delay or reduce the effects of aging. (Wrinkle prevention? Sign me up!)

If you're interested in increasing your lifeline, add more endurance to your workout routine. Endurance exercise includes everything cardio — from swimming to dancing — at an intense level for extended periods of time (hello romp session!).

In addition to longevity, exercise also keeps us sharp as a whip, influencing everything from our brain’s blood flow to cognitive functioning. In fact, research shows that specific cardio strengthens specific mental functions. For example, ballroom dancing helps with memory, or Tai Chi can help with problem solving.

If this new research won’t get you to get out there to break a sweat, we don’t know what will.

 

Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: A randomized crossover pilot study

Well shit I wrote about this in April 2013

Beet Juice Beats Hypertension

Why the fuck hasn't a diet stroke protocol been written on this in the past three years? Is it laziness or incompetence or stupidity? I see no other choice.

http://www.mdlinx.com/internal-medicine/medical-news-article/2016/06/10/hypertension-red-beet/6712497/?news_id=387&newsdt=061116&subspec_id=4&utm_source=WeeklyNL&utm_medium=newsletter&utm_content=Weeks-Best-Article&utm_campaign=article-section&category=latest-weekly

Journal of Human Hypertension, 06/10/2016 Asgary S, et al.

The clinicians examined the effect of raw beet juice (RBJ) and cooked beet (CB) on BP of hypertensive subjects. Although both forms of beetroot were effective in improving BP, endothelial function and systemic inflammation, the raw beetroot juice had greater antihypertensive effects. Also more improvement was observed in endothelial function and systemic inflammation with RBJ compared with CB.

Methods

• This was randomized crossover study.
• A total of 24 hypertensive subjects aged 25–68 years old were divided into two groups.
• One group took RBJ for 2 weeks and the other group took CB.
• After 2 weeks of treatment, both groups had a washout for 2 weeks then switched to the alternate treatment.
• Each participant consumed 250 ml day–1 of RBJ or 250 g day–1 of CB each for a period of 2 weeks.
• Body weight, BP, flow–mediated dilation (FMD), lipid profile and inflammatory parameters were measured at baseline and after each period.

Results

• According to the results, high–sensitivity C–reactive protein (hs–CRP) and tumour necrosis factor alpha (TNF–α) were significantly lower and FMD was significantly higher after treatment with RBJ compared with CB (P<0.05).
• FMD was significantly (P<0.05) increased, but systolic and diastolic BP, intracellular adhesion molecule–1 (ICAM–1), vascular endothelial adhesion molecule–1 (VCAM–1), hs–CRP, interleukin–6, E–selectin and TNF–α were significantly (P<0.05) decreased with RBJ or CB.
• Total antioxidant capacity was increased and non–high–density lipoprotein (HDL), low–density lipoprotein (LDL) and total cholesterol (TC) were decreased with RBJ but not with CB.

Go to PubMed Go to Abstract Print Article Summary Cat 2 CME Report

Could a beetroot a day keep the doctor at bay?

Maybe this will come up with exact amounts needed. I'm doing about 3-4 oz. of pickled beets daily but have no clue how much good it is doing. You might be able to add this to your diet stroke protocol in a couple hundred years.
http://medicalxpress.com/news/2016-05-beetroot-day-doctor-bay.html
QUT study is underway to discover whether beetroot juice could be a new 'super food' to improve vascular health, including blood coagulation and boosting immune cells, in older people and volunteers are wanted to take part.

Dr Oliver Neubauer, from QUT's Institute of Health and Biomedical Innovation, is seeking healthy men and women aged between 60 and 70 to take part in the world-first project. All they have to do is have blood samples taken before and after drinking beetroot juice.
"Beetroot juice is naturally rich in nitrate and recent discoveries have shown the benefits of dietary nitrate to humans," Dr Neubauer said.
"Dietary nitrate elicits anti-inflammatory, anti-coagulative and anti-thrombotic effects, all of which are beneficial for the health of blood vessels.
"Our study is the first to investigate the immediate effects of beetroot juice on factors affecting vascular health, particularly blood clotting, the body's immune cells characteristics, blood pressure and inflammatory issues in mature-aged people.
"The research will provide us with important information on the potential for a lifestyle-based intervention involving beetroot juice to prevent some age-associated diseases, preserve the function of blood vessels and promote healthy ageing."
Dr Neubauer said he was looking for men and women between 60 and 70 in a normal weight range with no evidence of acute or chronic diseases like severe cardiovascular disease, pulmonary, neural or musculoskeletal disease, osteoporotic fractures or diabetes.
"They must also be non-smokers, not suffering from acute or chronic pain and not engaged in regular exercise training," he said.
"To take part in the study volunteers are required to undergo a health screening which includes medical history, questionnaires on diet and physical activity and measurement of resting blood pressure and heart rate.
"If they are eligible to participate we then need them to come to our laboratories on two separate occasions over a two-week period. On each visit they will have blood and heart activities measured and blood collections taken at three and six hours after drinking either nitrate-rich or nitrate-depleted beetroot juice."
Dr Neubauer said the nitrate-depleted beetroot juice was provided by a UK firm and was only used for research purposes as a placebo.
He added that while there was some loss of nitrate in washing, peeling and/or cooking beetroots, the health benefits remained high and the same applied to other nitrate-rich foods such as leafy green vegetables.
"Beetroots, like all fruit and vegetables, have multiple benefits, but the fact they are rich in nitrates puts them into the 'super food' category," he said.

Explore further: Drinking cup of beetroot juice daily may help lower blood pressure

More information: For more information and to participate in the study, contact the research team on 3138 6174 or email oliver.neubauer@qut.edu.au or kyle.raubenheimer@qut.edu.au

Provided by: Queensland University of Technology

Effect of Hyperacute Administration (Within 6 Hours) of Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome After Stroke: Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial

Next steps would be to administer beet juice for nitric oxide benefits for the first week or so. So much research to conduct and no one following any strategy or plan.
http://www.ncbi.nlm.nih.gov/pubmed/26463698

Woodhouse L¹, Scutt P¹, Krishnan K¹, Berge E¹, Gommans J¹, Ntaios G¹, Wardlaw J¹, Sprigg N¹, Bath PM²; ENOS Investigators.

Author information

Abstract

BACKGROUND AND PURPOSE:

Nitric oxide donors are candidate treatments for acute stroke, potentially through hemodynamic, reperfusion, and neuroprotectant effects, especially if given early. Although the large Efficacy of Nitric Oxide in Stroke (ENOS) trial of transdermal glyceryl trinitrate (GTN) was neutral, a prespecified subgroup suggested that GTN improved functional outcome if administered early after stroke onset.

METHODS:

Prospective analysis of subgroup of patients randomized into the ENOS trial within 6 hours of stroke onset. Safety and efficacy of GTN versus no GTN were assessed using data on early and late outcomes.

RESULTS:

Two hundred seventy-three patients were randomized within 6 hours of ictus: mean (SD) age, 69.9 (12.7) years; men, 154 (56.4%); ischemic stroke, 208 (76.2%); Scandinavian Stroke Scale, 32.1 (11.9); and total anterior circulation syndrome, 86 (31.5%). When compared with no GTN, the first dose of GTN lowered blood pressure by 9.4/3.3 mm Hg (P<0.01, P=0.064) and shifted the modified Rankin Scale to a better outcome by day 90, adjusted common odds ratio, 0.51 (95% confidence interval, 0.32-0.80). Significant beneficial effects were also seen with GTN for disability (Barthel Index), quality of life (EuroQol-Visual Analogue Scale), cognition (telephone Mini-Mental State Examination), and mood (Zung Depression Scale). GTN was safe to administer with less serious adverse events by day 90 (GTN 18.8% versus no GTN 34.1%) and death (hazard ratio, 0.44; 95% confidence interval, 0.20-0.99; P=0.047).

CONCLUSIONS:

In a subgroup analysis of the large ENOS trial, transdermal GTN was safe to administer and associated with improved functional outcome and fewer deaths when administered within 6 hours of stroke onset.

CLINICAL TRIAL REGISTRATION:

URL: http://www.clinicaltrials.gov. Unique identifier: NCT00989716.

Cranberry juice consumption may protect against cardiovascular disease

What does your stroke diet protocol look like? Has your doctor even had one created by the nutritionist? Or is s/he WAITING FOR SOMEONE ELSE TO SOLVE THE PROBLEM?
So what the fuck is better? Beet juice or cranberry juice? A very simple question that no one will answer for 50 years because we have craptastic stroke associations. 

Cranberry juice consumption may protect against cardiovascular disease

Results from a new study presented at the Cranberry Health Research Conference preceding the annual Berry Health Benefits Symposium 2015 in Madison, WI, revealed that cranberry juice consumption may play a role in protecting against cardiovascular disease. Presented by principal investigator, Ana Rodriguez-Mateos, PhD, from the Division of Cardiology, Pulmonology and Vascular Medicine at the University Duesseldorf, Germany, the research uncovered a potent, dose-dependent relationship between cranberry juice and improved vascular function. Because vascular dysfunction, including limitations in blood flow, is a central feature in the development of atherosclerosis - improving vascular function can have a powerful, beneficial effect on a person's cardiovascular health.
"Cranberry juice is a rich source of phytonutrients, including proanthocyanidins, anthocyanins and phenolic acids," explains Dr. Rodriguez-Mateos. "Due to this robust profile of polyphenols, our team sought to evaluate the immediate vascular impact of drinking one, 450 ml (or 16 ounces) glass of cranberry juice with a different range of concentrations of cranberry-polyphenols."

In a randomized, controlled crossover trial, researchers gave ten healthy male subjects, between the ages of 18-40 years, 450 ml (just under 2 cups) of sweetened cranberry juice made from concentrate. The cranberry concentrate was prepared with water to concentrations ranging from 0 to 117%. The amount of cranberry-polyphenols increased with the concentration. Non-invasive measurements of vascular function including flow-mediated vasodilation (FMD), blood pressure and arterial stiffness were performed at baseline and at one, two, four, six and eight hours post-consumption. Blood and urine samples were collected for 24 hours following consumption to detect changes in plasma and urinary cranberry-derived polyphenols. Across the board, all of the cranberry juices benefited FMD - including 25% cranberry juice, equivalent to the commonly consumed cranberry juice cocktail (25-27%). The highest concentration of cranberry-polyphenol juice also showed improvements in systolic blood pressure.
Defending the health of the circulatory system - and improving vascular function - not only reduces the chance of developing atherosclerosis, but plays an important role in kidney function, hormone delivery and waste filtration.
"Our results lay the groundwork to better understand the array of potential vascular and cardiovascular health benefits of cranberry polyphenols," notes Dr. Rodriguez-Mateos. "Significant improvements in vascular function from drinking two cups of cranberry juice suggest an important role for cranberries in a heart-healthy diet."

Source:

Pollock Communications