VIDEO: Cardiovascular benefits of GLP-1 agonists ‘absolutely stunning’

 So no one in the medical world knows that stroke is no longer a cardiovascular disease?

(Stroke has been called neurological disease by the WHO since 2006) and no one seems to know that.

VIDEO: Cardiovascular benefits of GLP-1 agonists ‘absolutely stunning’

BOSTON — Emerging data on the cardiovascular benefits of GLP-1 receptor agonists indicate that these agents could transform cardiovascular care, much like statins did 30 years ago, Clyde W. Yancy, MD, MSc, MACP, MACC, FAHA, FHFSA, said.

In this video, Yancy, a professor and chief of cardiology at Northwestern University Feinberg School of Medicine, discusses findings from the SELECT trial, which showed that Wegovy (semaglutide 2.4 mg, Novo Nordisk) was associated with an additional 20% RR reduction in cardiovascular events compared with placebo among patients with pre-existing heart disease.

“This is in patients who entered the trial with a previous MI, with heart failure, with hypertension, a prior stroke or peripheral vascular disease,” Yancy said. “These are the patients we see ... The results were absolutely stunning.”

This is part of a six-video Healio Video Exclusive in which Yancy recaps his talk at the ACP Internal Medicine Meeting on important updates in cardiology.

Read the full article on Yancy’s talk here and check out the other videos in this series:

• VIDEO: Newly defined syndrome is ‘a brilliant concept’ on stages of CVD risk
• VIDEO: New CVD risk algorithm incorporates social determinants of health
• VIDEO: Small interfering RNA holds promise for cardiovascular care
• VIDEO: Use incidental calcification findings to estimate CVD risk
• VIDEO: Following Life’s Essential 8 leads to ‘much better outcomes’

References:

• Lincoff AM, et al. N Engl J Med. 2023;doi:10.1056/NEJMoa2307563.
• Yancy CW. Update in cardiology. Presented at: ACP Internal Medicine Meeting; April 18-20, 2024; Boston.

Sources/Disclosures

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Source:

Healio Interviews

Disclosures: Yancy reports no relevant financial disclosures.

A Lazarus Patient And The Limits Of A Lifesaving Stroke Procedure

It is positive stories like this that allow the stroke medical world to ignore all the failures in stroke.
With NO strategy and NO leadership nothing will get done for decades.
1. Only 10% of patients get to full recovery.
2. tPA only fully works to reverse the stroke 12% of the time. Known since 1996.
3. No protocols to prevent your 33% dementia chance post-stroke from an Australian study.
4. Nothing to alleviate your fatigue.
5. Nothing that will cure your spasticity.
6. Nothing on cognitive training unless you find this yourself.
7. No published stroke protocols.
8. No way to compare your stroke hospital results vs. other stroke hospitals. 

A Lazarus Patient And The Limits Of A Lifesaving Stroke Procedure

Pre-stroke CV risk factors may indicate higher stroke, dementia risk

It would be so simple for optimizing primary prevention if our doctors would just put together a diet stroke protocol that reduces blood pressure using commonly available foods and supplements. But that won't occur because we have no one in the stroke medical world that has two functioning neurons they can rub together. You, your children and grandchildren are screwed.

Pre-stroke CV risk factors may indicate higher stroke, dementia risk

Portegies MLP, et al. Stroke. 2016;doi:10.1161/STROKEAHA.116.014094.

According to new research, CVD risk factors such as high BP before a first stroke confer higher risk for subsequent stroke and dementia up to 5 years later.

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 “We already know that stroke patients have an increased risk of recurrent stroke and dementia. What we didn’t know was whether this increased risk persists for a long time after stroke and whether heart disease risk factors present before the first stroke influenced the risk of recurrent strokes or dementia,” M. Arfan Ikram, MD, PhD, from Erasmus University Medical Center in Rotterdam, Netherlands, said in a press release. “Our study found these risk factors influence future stroke and dementia and the risks persist for an extended period in some patients.”

The researchers analyzed based on propensity matching 1,237 patients with first-ever stroke and 4,928 participants without stroke from the population-based Rotterdam Study. Participants were matched based on sex, age, examination round, and date of selection. The outcomes of interest were stroke and dementia.

Ikram and colleagues calculated incidence rates of stroke and dementia for both groups and determined the population-attributable risk of prestroke CV risk factors for stroke and dementia.

Up to 1 year after first stroke, those with stroke had a threefold increased risk for stroke and a twofold increased risk for dementia compared with those without stroke, Ikram and colleagues wrote.

The researchers calculated that in the group with stroke, 39% (95% CI, 18-66) of recurrent strokes and 10% (95% CI, 0-91) of cases of dementia after stroke could be attributed to CV risk factors before stroke. The rates were similar in the group without stroke.

“Long-term risks of recurrent stroke and poststroke dementia remain high and are substantially influenced by prestroke risk factors, emphasizing the need for optimizing primary prevention,” the researchers wrote. – by Dave Quaile

Active Mind may Delay Alzheimer’s Symptoms, but not Underlying Disease

I guess I'll need to keep an active mind forever. Trying to change the stroke medical world will keep me busy until I die.
http://newsnetwork.mayoclinic.org/discussion/keeping-mind-active-may-delay-alzheimers-symptoms-but-not-underlying-disease-study-finds/