Study Links Tea, Berries and Dark Chocolate to Lower Parkinson's Risk

 Have your competent? doctor document THE EXACT PROTOCOL AMOUNTS that effectively reduce your extra risk of Parkinsons from your stroke to zero! NOT DOING SO IS PURE INCOMPETENCE! Firing should be the first punishment, then either keel hauling or tar and feathering.

Parkinson’s Disease May Have Link to Stroke March 2017 

Study Links Tea, Berries and Dark Chocolate to Lower Parkinson's Risk

Defining Social and Cultural Barriers to Global Stroke Care: A SVIN–Mission Thrombectomy Initiative

 The first barrier to break down is changing the word 'care' to RECOVERY! 

UNTIL THAT OCCURS YOU'RE NOT WORTH LISTENING TO! 

Defining Social and Cultural Barriers to Global Stroke Care: A SVIN–Mission Thrombectomy Initiative

Fawaz Al-Mufti, MD https://orcid.org/0000-0003-4461-7005, Eric Feldstein, MD,

Aarti Kishore Jain, BS, Nimrod Gozum, BS, 

Alexandria F. Naftchi, BS, Andre Calixte, BS, 

Eris Spirollari, BA, … Show All … on behalf of the Mission Thrombectomy Collaborative

Author Info & Affiliations

Ne

https://doi.org/10.1161/SVIN.125.002168

Abstract

 Stroke has become the single leading neurological illness that results in neurological disability and is the second most common cause of death worldwide. Approximately 85% of strokes are ischemic, whereas the remaining 15% are hemorrhagic. With the advent of increasingly effective(Not true, you are not delivering 100% recovery! And that IS MASSIVE FAILURE BY THE STROKE MEDICAL WORLD! You all need to be keel hauled!)

 treatment modalities, such as intravenous thrombolytics and endovascular mechanical thrombectomy, there has been a growing disparity in the ability to provide standard of care(NOT RECOVERY!), despite substantial efforts made in lower- and middle-income countries. substantial effort in high-income countries to provide the current standard of care(NOT RECOVERY!) to patients with stroke, with the hope of improving outcomes. Extensive research has shown that the disparities in treatment among various countries stem from multiple sociocultural barriers and the lack of robust healthcare infrastructure.(WRONG! It's because you haven't delivered 100% recovery protocols regardless of time to hospital! 

Pedro Bach-y-Rita recovered fully back in 1958 with only a partial brain! Aren't you smart enough to duplicate that?)

 The societal influences in play include the lack of knowledge of stroke symptoms, cultural beliefs, health, and spiritual fatalism, which are then associated with delayed healthcare-seeking behaviors. As a result, it is imperative to increase access to treatment for patients with stroke to address inequities in stroke care(NOT RECOVERY!) and diminish the global burden of stroke. This narrative review highlights causes of major gaps in stroke treatment infrastructure in several global communities and examines the pertinent sociocultural factors that impede progress in stroke treatment.

Graphical Abstract

Quality of rehabilitation care in Portuguese stroke units: findings from 2017–2018 and 2023 national cross‑sectional surveys

 Since you're measuring 'care' NOT RECOVERY; you're COMPLETELY FUCKING INCOMPETENT AND DESERVE TO BE KEEL HAULED!

There are no excuses for such incompetent crapola! I'd have you all fired!

Quality of rehabilitation care in Portuguese stroke units: findings from 2017–2018 and 2023 national cross‑sectional surveys

• oana Teles SarmentoDepartment of Medicine, Faculty of Medicine, University of Porto, Porto, Portugal; Department of Physical and Rehabilitation Medicine, Unidade Local de Saúde do Médio Ave, Vila Nova de Famalicão, Portugal
• Ana AlvesPhysical and Rehabilitation Clinic of S. Nicolau, Porto, Portugal
• Paulo Castro-ChavesRISE-Health, Faculty of Medicine, University of Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde de São João, Porto, Portugal
• Bárbara M. CruzDepartment of Physical and Rehabilitation Medicine, Centro Hospitalar Universitário Santo António, Porto, Portugal
• Cristina JácomeRISE-Health, Faculty of Medicine, University of Porto, Porto, Portugal

DOI: 

https://doi.org/10.2340/jrm.v58.44855

Keywords: 

Guideline Adherence, Health Services Research;, Quality Indicators, Rehabilitation, Stroke

Abstract

Objective: To evaluate adherence to stroke rehabilitation guidelines in Portuguese stroke units from the physicians’ perspective and examine changes over 6 years.

Design: A national cross-sectional survey across 2 time periods (2017–2018 and 2023).

Methods: Stroke units recognized by the Portuguese Stroke Society were invited to participate: 27 in 2017–2018 and 35 in 2023. A structured questionnaire, aligned with national and international guidelines, assessed 5 domains: team composition, care coordination, early assessment and planning, dysfunction assessments, and post-discharge planning.

Results: Response rates were 93% (n = 25) and 80% (n = 28). Most units (> 75%) had a physiatrist, physiotherapist, speech therapist, rehabilitation nurse, and social worker; only 20% had the full recommended team. Weekly stroke unit meetings were stable (88–89%), while rehabilitation team meetings increased markedly between the 2 periods (20% vs 72%). Rehabilitation started earlier on weekdays (89% vs 79%) than at weekends (68% vs 57%). Dysphagia screening was common (96% vs 89%), but neurogenic bladder assessment was rare (< 8%). The Modified Rankin Scale and Barthel Index were consistently used. Post-discharge planning remained high (92% vs 89%), with improved coordination between teams (48% vs 89%).

Conclusion: Portuguese Stroke Units demonstrated moderate-to-high adherence to rehabilitation guidelines, with progress in teamwork communication and care coordination, although important gaps remain.

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References

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Ferroptosis and Alzheimer's Disease: A New Insight into Neurodegeneration

Your doctor, if competent at all, should have already known about ferroptosis from this research from September 2017.  And should have initiated stroke treatment interventions from it. But I bet incompetence prevailed! No excuses are allowed, call that president and have these incompetent doctors fired!

 Dementia research leads to potential new stroke treatment

The latest here:

 Ferroptosis and Alzheimer's Disease: A New Insight into Neurodegeneration

Youfang Quan¹Hongwei Liu²Minheng Zhang³Meng Li⁴Bo He¹Ke Wang¹Xuewen Huang¹Shengyang Zhou⁵Zhongyu Han⁵Haixia Fan^4*

• ¹Chengdu University of Traditional Chinese Medicine, Chengdu, China
• ²Capital Medical University, Beijing, China
• ³The First People's Hospital of Jinzhong, Jinzhong, China
• ⁴Shanxi Medical University, Taiyuan, China
• ⁵Southeast University, Nanjing, China

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Alzheimer's disease (AD), a chronic and progressive neurodegenerative disorder, poses a significant threat to the health of the aging population. The pathological hallmarks of AD include the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs) within the brain. While substantial neuronal loss has been consistently observed in AD, the precise mechanisms underlying neuronal elimination remain incompletely understood. As a distinct form of regulated cell death, the contribution of ferroptosis to AD pathogenesis and progression warrants further investigation(If your doctors and hospital can't get this further research done, then it's time to keel haul them!). This review critically examines the amyloid cascade hypothesis within the context of AD, with particular emphasis on the molecular signatures of ferroptosis and their contributions to canonical AD pathogenesis and cognitive decline. We aim to provide an updated perspective on AD etiopathogenesis. Furthermore, we synthesize current therapeutic strategies targeting ferroptosis inhibition in AD, highlighting recent advances that hold significant implications for guiding present and future translational efforts.

Ferroptosis in neurological diseases: moving towards therapeutic intervention

 

Your doctor, if competent at all, should have already known about ferroptosis from this research from September 2017.  And should have initiated stroke treatment interventions from it. But I bet incompetence prevailed! No excuses are allowed, call that president and have these incompetent doctors fired!

 Dementia research leads to potential new stroke treatment

The latest here:

Ferroptosis in neurological diseases: moving towards therapeutic intervention

• Qing-Zhang Tuo, 
• Ashley I. Bush & 
• Peng Lei 

Molecular Psychiatry (2026)Cite this article

• 222 Accesses

• 1 Altmetric

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Abstract

Ferroptosis is a regulated cell death driven by iron-dependent lipid peroxidation and has been implicated in major neurological diseases. The brain is enriched in polyunsaturated fatty acids (PUFAs) and iron, which makes it particularly susceptible to lipid peroxidation, leading to ferroptosis. In neurological diseases such as Alzheimer’s disease (AD) and stroke, such mechanisms are dysregulated and contribute to neuronal loss. Physiologically, the lipid peroxidation resistance systems in the brain, including defenses (such as SOD, CAT, Prxs, GPxs) and repair systems (such as GPx4, FSP1), prevent ferroptosis and repair damaged phospholipid membranes. However, the efficacy of endogenous resistance systems is often compromised in pathological states, positioning exogenous antioxidants as promising therapeutic candidates. Future research(If your doctors and hospital can't get this further research done, then it's time to keel haul them!) could optimize the delivery of these compounds and explore new candidates that specifically target the ferroptosis signaling pathway to prevent neurodegeneration occurring in neurological diseases.

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Natural History of Stroke: Cause and Development

 WOW, pure incompetence proven by the need to do this study!

Natural History of Stroke: Cause and Development

ClinicalTrials.gov ID NCT00009243

 Sponsor National Institute of Neurological Disorders and Stroke (NINDS) Information Provided by Lawrence L Latour, Ph.D. ,Study Start (Actual) 2001-01-26 Enrollment (Estimated) 4000 Study Type Observational Last Update Posted 2025-12-19 

Study Overview The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations. It will 1) establish a registry of patients with cerebrovascular disease (stroke); 2) characterize the natural history of acute stroke and transient ischemic attacks (TIA)-an interruption of blood flow to the brain that causes stroke symptoms for a short period of time); and 3) evaluate the data to generate ideas for future studies.(ARE YOU THAT FUCKING INCOMPETENT YOU HAVEN'T BEEN KEEPING TRACK OF RESEARCH THAT LOOKS PROMISING?)

(Here for your perusal: See how fucking easy it is, if a stroke survivor can do that, WHY THE FUCK DO YOU NEED THESE Ph. D's? Just start running research, needing to do this research just proves your COMPLETE FUCKING INCOMPETENCE! I'd have you all keel hauled!)

further research (287 posts to August 2012)

human testing (237 posts to March 20110)

Patients 18 years of age or older with suspected acute stroke or TIA may be eligible for this study. Subjects will be recruited from patients who present with stroke at the emergency department of Suburban Hospital in Bethesda, Maryland. The study will gather data collected from diagnostic and laboratory tests the patient undergoes as part of standard medical care, including findings of medical and neurological examinations and other tests. In addition, studies will be done for research purposes only to gather data about stroke and TIA. These may include the following: * Blood and urine tests not more than 2 tablespoons of blood will be drawn for various tests. * Electrocardiogram (EKG) (heart tracing)-electrodes placed on the chest wall detect the heartbeat and heart rhythm. * Computed tomography (CT) scan of the head-specialized X-rays are used to obtain images of the brain. * Magnetic resonance imaging (MRI) of the brain-a strong magnetic field and radio waves are used to produce images that provide information about the brain tissue and blood vessels. * Transcranial Doppler (TCD)-sound waves are used to image the arteries of the brain and neck. * Echocardiogram-sound waves are used to image the heart and evaluate heart function. Patients may be asked to return to Suburban Hospital for follow-up testing in 1, 3, and/or 12 months, when some of these tests may be repeated to assess changes over time ... To learn more, visitClinicalTrials.gov 

Contacts and Locations Contact Information Study Contact Name:Nicole L Peterkin Email nicole.peterkin@nih.gov Study Contact Backup Name Lawrence L Latour, Ph.D. Phone (301) 435-2395 Email latourl@ninds.nih.gov United States Locations District of Columbia Washington D.C., District of Columbia, United States 20010 Medstar Washington Hospital Center Maryland Bethesda, Maryland, United States 20814 Suburban Hospital - Johns Hopkins Medicine Bethesda, Maryland, United States 20892 National Institutes of Health Clinical Center Participation Criteria INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: Aged >=18 Presented to participating study site (ED, ICU, or inpatient unit) with or at risk of acute stroke, TIA, or other disturbances of cerebrovascular circulation7nbsp;An individual who meets any of the following criteria will be excluded from participation in this study: Subjects with contraindication to MRI scanning will be excluded from any testing which involves the use of MRI. The contraindications include subjects with the following devices or conditions: Implanted neural stimulator Implanted cardiac pacemaker or defibrillator Ocular foreign body (e.g. metal shavings) Metal shrapnel or bullet Any implanted device that is incompatible with MRI Subjects with a condition precluding entry in the scanner (e.g. morbid obesity, Claustrophobia, etc.) will not be included in the MRI portion of this study. Pregnancy Ages Eligible for Study Minimum Eligible Age Not available Maximum Eligible Age Elderly Age Groups adult, older_adult Eligible Sexes all Accepts Healthy Volunteers:No Sampling Method Non-Probability Sample Study Population Subjects are recruited from the collaborative stroke programs between NINDS and affiliated hospitals (Suburban Hospital and MedStar Washington Hospital Center) and will be followed for the duration of their hospitalization. Select subjects will then be seen for follow up for up to one year.