A multicenter clinical nomogram for predicting post-stroke fatigue: development and validation

 

Will your competent? doctor and hospital ensure research is completed to determine WHAT WILL CURE POST STROKE FATIGUE? Not manage or anything less than a FULL CURE!

This prediction crapola is COMPLETELY FUCKING USELESS!

Let's see how long everyone in stroke has been incompetent at this problem!

• post stroke fatigue (60 posts to January 2018)

At least half of all stroke survivors experience fatigue Known since March 2017

Or is it 70%? Known since March 2015.

Or is it 40%? Known since September 2017.

A multicenter clinical nomogram for predicting post-stroke fatigue: development and validation

• X

  Xiaoqing Tao 1†

• S

  Shan Wang 2†

• L

  Li Pang 1

• Y

  Yiling Sun 1

• 

  Yifei Ji 1,2*

• 

  Yu Ren 1,3*

• 1. Department of Neurology, Beijing Anzhen Nanchong Hospital of Capital Medical University & Nanchong Central Hospital, Nanchong, Sichuan, China

• 2. Department of Neurology, The Second Clinical Medical College of North Sichuan Medical College, Nanchong, Sichuan, China

Abstract

Background and purpose: 

Post-stroke fatigue (PSF) is a common and disabling complication after stroke, yet its pathophysiological mechanisms remain unclear and reliable prediction tools are lacking. This study aimed to identify risk factors for PSF and develop a visualized nomogram for early prediction based on clinical and laboratory data.

Methods: 

We conducted a retrospective cohort study of stroke patients hospitalized in the Department of Neurology at the First Affiliated Hospital of Chongqing Medical University were randomly split into training (n = 592) and internal validation (n = 254) sets. An independent cohort of 440 patients from Nanchong Central Hospital was used as the external validation cohort. Fatigue was assessed at week 4 after admission using the Fatigue Severity Scale (FSS) and Fatigue Assessment Scale (FAS). Demographic, clinical, imaging, and laboratory data were collected. LASSO regression was used for variable selection, followed by multivariate logistic regression to construct a nomogram. Model performance was assessed using the area under the curve (AUC), calibration curves, and decision curve analysis (DCA), with internal and external validation via bootstrapping.

Results: 

A total of 846 stroke patients were enrolled and randomly split into training (n = 592), internal validation (n = 254) and external validation (n = 440) sets. Eight independent predictors of PSF were identified: brainstem, basal ganglia, and thalamic lesions, female sex, older age, modified Rankin Scale (mRS) score, white blood cell (WBC) count, and C-reactive protein (CRP) level (all p < 0.05). The nomogram showed good discrimination (AUC: 0.870, 0.862, and 0.672 for training, internal, and external validation sets, respectively), calibration, and clinical utility.

Conclusion: 

We developed a clinically applicable nomogram based on routinely available data for early prediction of PSF. The model demonstrated good accuracy and may aid in identifying high-risk patients to guide timely intervention.

Poststroke fatigue in subacute and chronic stroke rehabilitation phase: prevalence, associated factors and impact on self-efficacy and functional ability

 Prevalence has been known for over a decade. WHY THE FUCK AREN'T YOU CURING FATIGUE? This did nothing useful, you're all fired!

At least half of all stroke survivors experience fatigue Or is it 70%?

Or is it 40%?

Poststroke fatigue in subacute and chronic stroke rehabilitation phase: prevalence, associated factors and impact on self-efficacy and functional ability

•,,,

Abstract

 Background Stroke is a leading cause of death and long-term disability worldwide, with low-income and middle-income countries accounting for about 87% of stroke-related deaths and disability-adjusted life-years. Among poststroke complications, poststroke fatigue is a common but often under-recognised condition characterised by emotional, cognitive and physical exhaustion unrelated to exertion and not relieved by rest. Poststroke fatigue can hinder functional recovery, yet it remains underassessed in the study area. So this study investigates the prevalence, associated factors and impact of poststroke fatigue on self-efficacy and activities of daily living.

Methods A hospital-based cross-sectional study was conducted through a systematic random sampling technique on 370 study participants. The Fatigue Severity Scale, Nottingham Extended Activities of Daily Living and Stroke Self-efficacy Questionnaire were used to collect questionnaires related to fatigue and its impact. The data were analysed on SPSS using binary logistic regression to assess associated factors and ordinal logistic regression to assess impacts of fatigue on self-efficacy and activities of daily living.

Result Fatigue was reported by 65.4% of participants (95% CI 60.30% to 70.20%) during the subacute and chronic rehabilitation phases. Older age, both overweight and underweight body mass index, National Institutes of Health Stroke Scale ≥12, lacked physiotherapy follow-up and experiencing depression were associated with poststroke fatigue with 95% CI and p<0.05. Moreover, individuals with poststroke fatigue were approximately 5.4 times less likely to report higher functional levels and 3.6 times less likely to demonstrate greater self-efficacy compared with those without fatigue.

Conclusions Poststroke fatigue is highly prevalent among stroke survivors and negatively impacts both self-efficacy and functional ability. These findings highlight the need for early identification and targeted management of fatigue to improve rehabilitation outcomes and quality of life in stroke survivors.

What is already known on this topic

• Poststroke fatigue is a common and disabling consequence of stroke, often persisting into the subacute and chronic phases of recovery.

What this study adds

• Importantly, the study quantifies the impact of fatigue in the study setting and our country, demonstrating that individuals without fatigue are substantially more likely to achieve better functional outcomes and self-efficacy. These findings provide a more comprehensive understanding by assessing prevalence, factors and impact of stroke survivors in low-resource hospital settings.

How this study might affect research, practice or policy

• This study is the first of its kind in our country to comprehensively assess the poststroke fatigue and its functional and psychological impacts. Therefore, the study underscores the importance of strengthening poststroke care infrastructure, including accessible rehabilitation services and mental health support, particularly in resource-limited settings.

Stroke Experts Challenge "90-Day Recovery" Myth: New Research Shows Patients Need Long-Term Care

All this is why everything in stroke is a COMPLETE FUCKING FAILURE! No one in the world is working on 100% recovery!

'Care' is NOT RECOVERY!

Stroke Experts Challenge "90-Day Recovery" Myth: New Research Shows Patients Need Long-Term Care

Centre for Neuro Skills

Tue, January 13, 2026 at 8:00 AM CST 5 min read

Centre for Neuro Skills

Study published by Centre for Neuro Skills researchers in Brain Injury journal argues current insurance policies leave stroke survivors with preventable disabilities and cost society billions

BAKERSFIELD, Calif., Jan. 13, 2026 (GLOBE NEWSWIRE) -- Stroke survivors need ongoing care far beyond the traditional 90-day recovery window, according to a recently published peer-reviewed article written by the Centre for Neuro Skills (CNS) research team. The article presents evidence that challenges current healthcare practices, limiting stroke treatment to the first 60-90 days post-injury. It indicates that a stroke should be treated as a chronic condition rather than a one-time medical event.

Brent-Mark-Grace-Stephanie-FIN_121925

From left: Brent E. Masel, Mark J. Ashley, Stefanie N. Howell and Grace S. Griesbach

The review article published in the journal Brain Injury, "Stroke as a chronic health condition: a case for continued care(NOT RECOVERY!)," is authored by CNS researchers Brent E. Masel, Mark J. Ashley, Stefanie N. Howell and Grace S. Griesbach. It presents compelling evidence that stroke survivors can continue to improve with therapy well beyond the traditional 3-6 month "plateau" assumption that drives current insurance reimbursement policies.

"Stroke is disease causative and disease accelerative," the researchers write. "Despite the fact that the Centers for Medicare and Medicaid Services has classified stroke as a chronic condition, the focus of care(NOT RECOVERY!) remains on the first 60-90 days after the stroke. There is very little scientific evidence supporting the limits imposed on stroke rehabilitation."

The Cost of Inadequate Long-Term Care

In the US, the average lifetime cost of stroke care(NOT RECOVERY!) per patient is estimated at $140,048.

"Although more intense comprehensive long-term stroke rehabilitation would add to the healthcare financial burden, it would potentially reduce disability and long-term costs to society," the authors state. Among young stroke survivors aged 18-50, nearly 47% were unemployed five years post-stroke, with a 2-3 times greater unemployment rate than their non-injured peers after eight years.

Medical Complications Extend Far Beyond Acute Period

The CNS research highlights that medical complications occur in 67% of stroke survivors, with two-thirds experiencing at least one complication and 25% suffering two or more. The most common complications include depression, pain, falls, cognitive impairment and sleep disorders - many of which develop or persist well beyond the initial months.

Key findings include:

• More than 50% of stroke survivors report cognitive impairment beyond the first year

• About one in four stroke survivors (25-28%) develop depression(You prevent depression by having EXACT 100% RECOVERY PROTOCOLS!)

• More than 70% develop obstructive sleep apnea, yet only 6% receive formal sleep testing

• 36-51% experience post-stroke fatigue(What is the EXACT CURE FOR THAT?)

• 30% develop dementia

• Stroke survivors face a 30% risk of a second stroke within five years—nine times the risk of the general population