Direct Transfer to Angio-Suite Versus Computed Tomography–Transit in Patients Receiving Mechanical Thrombectomy

Useless piece of shit research. 

NOTHING ON MEASURING 100% RECOVERY! 

Oops, I'm not playing by the polite rules of Dale Carnegie,  'How to Win Friends and Influence People'. 

Politeness will never solve anything in stroke. Yes, I'm a bomb thrower and proud of it. Someday a stroke 'leader' will ream me out for making them look bad by being truthful , I look forward to that day.

 

Direct Transfer to Angio-Suite Versus Computed Tomography–Transit in Patients Receiving Mechanical Thrombectomy

Johannes A.R. Pfaff

,

Silvia Schönenberger

,

Christian Herweh

,

Christian Ulfert

,

Simon Nagel

,

Peter A. Ringleb

,

Martin Bendszus

,

Markus A. Möhlenbruch

Originally published10 Aug 2020https://doi.org/10.1161/STROKEAHA.120.029905Stroke. 2020;51:2630–2638

Abstract

Background and Purpose:

To quantify workflow metrics in patients receiving stroke imaging (noncontrast-enhanced computed tomography [CT] and CT-angiography) in either a computed-tomography scanner suite (CT-Transit [CTT]) or an angio-suite (direct transfer to angio-suite—[DTAS]—using flat-panel CT) before undergoing mechanical thrombectomy.

Methods:

Prospective, single-center investigator initiated randomized controlled trial in a comprehensive stroke center focusing on time from imaging to groin puncture (primary end point) and time from hospital admission to final angiographic result (secondary end point) in patients receiving mechanical thrombectomy for anterior circulation large vessel occlusion after randomization to the CTT or DTAS pathway.

Results:

The trial was stopped early after the enrollment of n=60 patients (CTT: n=34/60 [56.7 %]; DTAS: n=26/60 [43.3%]) of n=110 planned patients because of a preplanned interim analysis. Time from imaging to groin puncture was shorter in DTAS-patients (in minutes, median [interquartile range]: CTT: 26 [23–32]; DTAS: 19 [15–23]; P value: 0.001). Time from hospital admission to stroke imaging was shorter in patients randomized to DTAS (CTT: 12 (7–18); DTAS: 21 (15–25), P value: 0.007). Time from hospital admission to final angiographic reperfusion was comparable between patient groups (CTT: 78 [58–92], DTAS: 80 [66–118]; P value: 0.067).

Conclusions:

This trial showed a reduction in time(Wrong endpoint to be measuring.) from imaging to groin-puncture when patients are transferred directly to the angiosuite for advanced stroke-imaging compared with imaging in a CT scanner suite. This time saving was outweighed by a longer admission to imaging time and could not translate into a shorter time to final angiographic reperfusion in this trial.

Footnotes

For Sources of Funding and Disclosures, see page 2637.

The Data Supplement is available with this article at https://www.ahajournals.org/doi/suppl/10.1161/STROKEAHA.120.029905.

Correspondence to: Markus A. Möhlenbruch, MD, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. Email markus.moehlenbruch@med.uni-heidelberg.de

 

Addressing the Gaps in Post-Stroke Sexual Activity Rehabilitation: Patient Perspectives

Survivors don't want information, they want to do the actual deed. What are the protocols to get there?   I need multiple cures to get back to doing missionary style sex. 

Missionary style sex just doesn't work anymore, neither does the Queens's throne, the Mare, or the Swing.
Problems:

1. Fingers and thumb will not stay flat.

2. Wrist collapses.

3. Elbow collapses.

4. Bicep spasticity pulls everything out of line.

All this is why you need to be doing lots of sex, why the hell can't your doctor get you fucking again?

Sexual Frequency Predicts Greater Well-Being, But More is Not Always Better

 

Sex after stroke

 

Sex linked to better brain power in older age

Sex: The Ultimate Full Body Workout

 

Better Memory From This Extremely Pleasurable Activity - Sex

 

WHY SEX IS BETTER FOR YOUR BRAIN THAN SUDOKU 

 

Sex linked to better brain power in older age

 

Good News About Sex- It Doesn't Cause a Stroke

 

Sex Does Not Increase Heart Attack Risk - What about stroke?

 

Frequent orgasms may protect against heart attacks

 

An orgasm a day keeps the doctor away!

In case you don't have a partner she could prescribe this.

Electrosex

And the benefits of marijuana for sex here:

Sex, Marijuana and Baby Booms

The latest here:

 Worthless piece of shit research.

 

Addressing the Gaps in Post-Stroke Sexual Activity Rehabilitation: Patient Perspectives

Sarah Prior ^1,* , Nicole Reeves ¹, Gregory Peterson ¹, Linda Jaffray ¹ and Steven Campbell ²

¹

School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania 7000, Australia

²

School of Health Sciences, College of Health and Medicine, University of Tasmania, Newnham Drive, Newnham, Tasmania 7250, Australia

^*

Author to whom correspondence should be addressed.

Received: 6 January 2019 / Revised: 31 January 2019 / Accepted: 31 January 2019 / Published: 5 February 2019

Full-Text   |   PDF [179 KB, uploaded 5 February 2019]   |   Review Reports

Abstract

Sexual dysfunction is common but often under-recognised or neglected after stroke. This study sought to identify the existing methods for providing information and discussion on post-stroke sexual activity, and perceived gaps from the patient perspective. A sample of 1265 participants who had been admitted to any of the four major public hospitals in Tasmania, Australia, with stroke (International Classification of Diseases (ICD-10) group B70) were mailed a survey assessing their experiences with, and opinions about, receipt of post-stroke sexual activity education. One hundred and eighty-three participants (14.5%) responded; of these, 65% were male and the mean age was 69.1 years. The results indicated that, whilst over 30% or participants wanted to receive information related to post-stroke sexual activity, only a small proportion of participants (8.2%) had received this. In terms of the method of receiving this information, participants preferred to receive this from a doctor in a private discussion with or without their partner present. The delivery of post-stroke sexual activity information and education is inconsistent and fails to meet patient needs within major Tasmanian hospitals, highlighting the importance of developing sound, routine, post-stroke education and information processes. View Full-Text

Keywords: stroke; rehabilitation; sexuality; sexual dysfunction; education; personal satisfaction

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Prior, S.; Reeves, N.; Peterson, G.; Jaffray, L.; Campbell, S. Addressing the Gaps in Post-Stroke Sexual Activity Rehabilitation: Patient Perspectives. Healthcare 2019, 7, 25.

Neuroprotective and Neurological/Cognitive Enhancement Effects of Curcumin after Brain Ischemia Injury with Alzheimer’s Disease Phenotype

Useless piece of shit research. No amounts to take or timeframe. Followup will be required which will NEVER OCCUR. 

Our fucking failures of stroke associations will DO NOTHING. Your doctor will DO NOTHING. Your stroke hospital will DO NOTHING.  You're screwed. 

And why are they doing NOTHING? Laziness? Incompetence? Or just don't care? No leadership? No strategy? Not my job?

Oops, I'm calling into question the capability of the stroke medical world. Bad, bad Dean.

I'm not playing by the polite rules of Dale Carnegie, 'How to Win Friends and Influence People'. 
Politeness will never solve anything in stroke.

This one line in the full text is appalling;

Therefore, due to the lack of translation of experimental neuroprotective agents for use in clinical conditions [41], we have focused our attention on improving functional outcomes after ischemia, instead of protecting neurons during ischemic damage.

Meaning they have given up on stopping the 5 causes of the neuronal cascade of death in the first week. LAZY BASTARDS, LEADERS TACKLE DIFFICULT PROBLEMS THEY DON'T FUCKING RUN AWAY. I SUGGEST COURT MARTIAL WITH THE REQUISITE PUNISHMENT, THAT MIGHT CONCENTRATE THE MIND. Shouting is required, the stroke medical world must be deaf to listening to survivors. It must be the only reason I have not been contacted by any stroke doctor or hospital. They can't be afraid of poor stroke-addled me.

 

 

Neuroprotective and Neurological/Cognitive Enhancement Effects of Curcumin after Brain Ischemia Injury with Alzheimer’s Disease Phenotype

Ryszard Pluta ^1,* , Marzena Ułamek-Kozioł ^1,2 and Stanisław J. Czuczwar ³

¹

Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, 02-106 Warsaw, Poland

²

First Department of Neurology, Institute of Psychiatry and Neurology, 02-957 Warsaw, Poland

³

Department of Pathophysiology, Medical University of Lublin, 20-090 Lublin, Poland

^*

Author to whom correspondence should be addressed.

Received: 16 November 2018 / Revised: 4 December 2018 / Accepted: 10 December 2018 / Published: 12 December 2018

(This article belongs to the Special Issue Curcumin in Health and Disease)

Full-Text   |   PDF [278 KB, uploaded 12 December 2018]

Abstract

In recent years, ongoing interest in ischemic brain injury research has provided data showing that ischemic episodes are involved in the development of Alzheimer’s disease-like neuropathology. Brain ischemia is the second naturally occurring neuropathology, such as Alzheimer’s disease, which causes the death of neurons in the CA1 region of the hippocampus. In addition, brain ischemia was considered the most effective predictor of the development of full-blown dementia of Alzheimer’s disease phenotype with a debilitating effect on the patient. Recent knowledge on the activation of Alzheimer’s disease-related genes and proteins—e.g., amyloid protein precursor and tau protein—as well as brain ischemia and Alzheimer’s disease neuropathology indicate that similar processes contribute to neuronal death and disintegration of brain tissue in both disorders. Although brain ischemia is one of the main causes of death in the world, there is no effective therapy to improve the structural and functional outcomes of this disorder. In this review, we consider the promising role of the protective action of curcumin after ischemic brain injury. Studies of the pharmacological properties of curcumin after brain ischemia have shown that curcumin has several therapeutic properties that include anti-excitotoxic, anti-oxidant, anti-apoptotic, anti-hyperhomocysteinemia and anti-inflammatory effects, mitochondrial protection, as well as increasing neuronal lifespan and promoting neurogenesis. In addition, curcumin also exerts anti-amyloidogenic effects and affects the brain’s tau protein. These results suggest that curcumin may be able to serve as a potential preventive and therapeutic agent in neurodegenerative brain disorders. View Full-Text

Keywords: brain ischemia; curcumin; Alzheimer’s disease; neurodegeneration; amyloid; tau protein; autophagy; mitophagy; apoptosis; genes

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Pluta, R.; Ułamek-Kozioł, M.; Czuczwar, S.J. Neuroprotective and Neurological/Cognitive Enhancement Effects of Curcumin after Brain Ischemia Injury with Alzheimer’s Disease Phenotype. Int. J. Mol. Sci. 2018, 19, 4002.

Support the Global Stroke Bill of Rights

What a complete and total piece of shit. NOTHING on 100% recovery, this just allows your doctors and stroke hospitals to continue their incompetence for the foreseeable future.  

Support the Global Stroke Bill of Rights 

There is never a reason to support incompetency.

 

Action Plan for Stroke in Europe 2018–2030

What an absolute lazy piece of shit. 

NOTHING on the neuronal cascade of death.

NOTHING on 100% recovery 

It is as if they have never talked to a stroke survivor in their life and have no clue on what research already out there just needs human testing followup. My god, they all need to be fired.  But then Bo Norrving was involved so you can't expect much. His tenure as WSO president didn't accomplish much that I could identify.

Action Plan for Stroke in Europe 2018–2030 

Show all authors

Bo Norrving, Jon Barrick, Antoni Davalos, ...

First Published October 29, 2018 Research Article

https://doi.org/10.1177/2396987318808719

Article information

Abstract

Abstract

Two previous pan-European consensus meetings, the 1995 and 2006 Helsingborg meetings, were convened to review the scientific evidence and the state of current services to identify priorities for research and development and to set targets for the development of stroke care for the decade to follow. Adhering to the same format, the European Stroke Organisation (ESO) prepared a European Stroke Action Plan (ESAP) for the years 2018 to 2030, in cooperation with the Stroke Alliance for Europe (SAFE). The ESAP included seven domains: primary prevention, organisation of stroke services, management of acute stroke, secondary prevention, rehabilitation, evaluation of stroke outcome and quality assessment and life after stroke. Research priorities for translational stroke research were also identified. Documents were prepared by a working group and were open to public comments. The final document was prepared after a workshop in Munich on 21–23 March 2018. Four overarching targets for 2030 were identified: (1) to reduce the absolute number of strokes in Europe by 10%, (2) to treat 90% or more of all patients with stroke in Europe in a dedicated stroke unit as the first level of care, (3) to have national plans for stroke encompassing the entire chain of care, (4) to fully implement national strategies for multisector public health interventions. Overall, 30 targets and 72 research priorities were identified for the seven domains. The ESAP provides a basic road map and sets targets for the implementation of evidence-based preventive actions and stroke services to 2030.

Keywords Stroke, epidemiology, prevention, treatment, stroke services, strategic planning, treaties, quality assurance, Europe

Introduction

Stroke remains one of the leading causes of death and disability in Europe, and projections show that with a ‘business as usual’ approach, the burden of stroke will not decrease in the next decade or beyond. An important contributing factor to this is that the number of older persons in Europe is rising, with a projected increase of 35% between 2017 and 2050.¹ Fortunately, there is compelling evidence that stroke is highly preventable, treatable and manageable, and the potential exists to drastically reduce the burden of stroke and its long-term consequences. However, this requires the joint actions of ministries of health, other governmental bodies, scientific and stroke support organisations, healthcare professionals, clinical and preclinical researchers and the pharmaceutical and device industries.
To this end, two previous pan-European consensus meetings, the 1995 and 2006 Helsingborg meetings,^2,3 were convened to review the scientific evidence and the state of current services and to set targets for the development of stroke care for the decade to follow. The European Stroke Organisation (ESO) has prepared a European Stroke Action Plan (ESAP) for the years 2018 to 2030, in cooperation with the Stroke Alliance for Europe (SAFE). The ESAP adheres to the format of the Helsingborg Declarations, presenting a review of the ‘state of the art’, the state of current services, research and development priorities and targets for a series of domains in stroke care (organisation of stroke services, management of acute stroke, prevention, rehabilitation, evaluation of stroke outcome and quality assessment). The ESAP includes two additional domains, on primary prevention and life after stroke, along with research and development priorities for translational stroke research. ESAP 2018‒2030 complements the WHO Global Action Plan on non-communicable diseases (NCDs) 2013–2020, the WHO-Europe NCD Action Plan and the UN Sustainable Development Goals for 2015 to 2030.

Overarching targets for 2030

For each domain of the 2018 to 2030 ESAP, specific targets are being set, as detailed in the following sections. Beyond these targets, four overarching targets for 2030 have been identified:

1. to reduce the absolute number of strokes in Europe by 10%
2. to treat 90% or more of all patients with stroke in Europe in a dedicated stroke unit as the first level of care
3. to have national plans for stroke encompassing the entire chain of care from primary prevention to life after stroke.
4. to fully implement national strategies for multisector public health interventions to promote and facilitate a healthy lifestyle, and reduce environmental (including air pollution), socioeconomic and educational factors that increase the risk of stroke.

A Virtual Reality Loop and Wire Game for Stroke Rehabilitation

You can have your doctor read these 8 pages and compare it to all these other virtual reality pieces already out there. Isn't it great that tens of thousands of doctors have to do this individually because we have fucking failures of stroke associations that can't do this just once and distribute it around the world? Lovely piece of crap stroke world we have, isn't it? 

Oops, my stroke-addled brain is acting up again. Thinking I know more about how stroke should be solved that all these highly trained stroke specialists. I call absolute stupidity out when I see it and that doesn't take much brains. 

• virtual (2)
• virtual avatars (1)
• virtual environment (1)
• virtual hugs (1)
• Virtual International Stroke Trials Archive (1)
• virtual reality (105)
• virtual reality games (5)
• virtual reality goggles (1)
• virtual reality training (13)
• virtual scalpel (1)
• virtual walking training program (2)

A Virtual Reality Loop and Wire Game for Stroke Rehabilitation

Guidelines for Stroke Rehabilitation and Recovery: Tailoring Care to Patients’ Needs and Improving..

What a useless piece of shit. Guidelines and care, NOT PROTOCOLS OR RESULTS. Do they think we are stupid and don't realize that our stroke professionals know ABSOLUTELY NOTHING about getting 100% recovered?

Guidelines for Stroke Rehabilitation and Recovery: Tailoring Care to Patients’ Needs and Improving.. 

Stroke AHA/ASA

Get the latest science behind #StrokeRehab. Register now for our #Stroke Rehab Webinar on October 8th at 1 pm CDT! http://spr.ly/6014D2k1A

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