Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label divorce. Show all posts
Showing posts with label divorce. Show all posts

Friday, July 10, 2026

There’s one thing almost all happy people have in common

 I have a lot of people that I can confide in. And all because I got divorced.

There’s one thing almost all happy people have in common


The longest-running study of adult life has tracked what actually predicts happiness and health for nearly a century.

Key Takeaways

  • In an 88-year Harvard study, relationship satisfaction was a stronger predictor of long-term health and happiness than wealth, career success, or even cholesterol levels.
  • A small group of close, trustworthy friends benefits you more than a wide circle of acquaintances, and those relationships work as real protective buffers against life’s stressors, lowering cortisol and improving resilience.
  • The strongest connections come from feeling safe enough to disagree, express negative feelings, and repair conflict, rather than avoiding it or performing perfectly.

What does it take to be happy? It’s a question some people spend their lifetime trying to answer. But thanks to an 88-year-long study, we finally have an answer.

Since it began in 1938, the Harvard Study of Adult Development has grown to become the longest study of adult life ever conducted. This includes collecting data on what best predicts health and well-being—including happiness—later in life. 

Roughly 30 years ago, researchers began to observe a connection between close relationships and happiness. Though it’s not definitive proof that relationships cause happiness, the data suggest that they’re a better indicator of happiness than wealth, fame, hard work, intelligence, or “good” genes. Here’s what the long-running study has found, and what it means for how we invest our time and attention every day.

What the Study Tells Us About Happiness

In short, the study has found that having strong, healthy relationships is one of the biggest factors in living a happy and healthy life. “People who were more satisfied with their relationships in middle age were usually healthier when they got older, recovered from illnesses better, and lived longer,” says Cynthia Vejar, PhD, the director and associate professor of clinical mental health counseling at Lebanon Valley College. For example, the researchers found that relationship satisfaction at age 50 was a better predictor of health at age 80 than cholesterol levels. 

More specifically, the research found that having high-quality relationships is the strongest predictor of happiness, physical health, and longevity. “On the flip side, the study demonstrated the detrimental effects of social isolation, noting that loneliness is a significant risk factor for poorer physical health, increased cognitive decline, worse mental health, and shorter lifespan,” says Gina Radice-Vella, PsyD, chief psychologist at Jersey Shore University Medical Center. 

One important distinction, however, is that it’s not necessarily the quantity of relationships you have—instead, the quality of the relationships matters. “Having a smaller group of close, trustworthy, and supportive friends has greater benefits than having many acquaintances,” Radice-Vella explains. 

The Benefits of High-Quality Relationships

High-quality, satisfying relationships serve as protective buffers against life’s stressors

“Research indicates that individuals with high relationship satisfaction are better able to cope with the negative effects of poor health, leading to better outcomes and better overall health,” Radice-Vella says. “Feeling a sense of secure connection reduces overall activation of our body’s stress response system, lowering cortisol levels and improving overall functioning.” 

Social connections and a support system can be important when we’re confronted with some of life’s most stressful events, such as job loss, loss of a loved one, a serious health condition, and divorce, among other things, she says. “They can remind us of our value when our self-esteem is bruised, and cheer us on when we’re not feeling optimistic,” she explains. “They can redirect our mood with a long, comforting phone call, stopping by to provide company, or to take a walk or to grab a bite or cup of coffee.” 

Strong relationships also provide a sense of emotional security. “People who experience being accepted for who they are, feeling understood by others, and having someone to support them through the ups and downs in life can have a more resilient response to stressors,” says Kat Grassetti, LCSW, clinical director at Monima Wellness. “They will still have hardships, but at least the hardships will be easier to manage, and they won’t feel so isolated.

What Do High-Quality Relationships Look Like?

The healthiest relationships are not completely drama-free. In fact, the Harvard study notes that high-quality relationships don’t have to be free from conflict.

Rather, higher-quality connections are based on trusting each other consistently and respecting one another, rather than being perfect. “This provides a space for individuals to have the ability to express negative feelings without fear of criticism, and an opportunity to resolve disagreements as opposed to avoiding them,” Grassetti says. “Often, feeling emotional safety in order to be genuine is much more important with regard to having a healthy connection with someone as opposed to never disagreeing.”

High-quality relationships are based on trust, support, and respect. “They are relationships where people can be honest with each other, rely on one another during difficult times, and feel accepted for who they are,” Vejar says. “The study also found that couples who were happy in their marriages were better able to stay positive even when they experienced health problems later in life.”

But that’s not all: The study highlights the importance of tending to the relationship. “In other words, maintaining strong relationships requires ongoing and intentional effort and attention,” Radice-Vella says.

What the Study Can Teach Us About Time and Energy

The results of the Harvard Study confirm what many of us have long suspected: A fulfilling life is not achieved through accomplishments, earnings, or belongings. “Instead, genuine happiness is defined by the people we surround ourselves with and how we nurture our relationships and connections with others,” Radice-Vella says. 

The research findings also suggest that we should prioritize actions that enhance the quality of relationships, like cultivating kindness, being fully present and engaged when with our loved ones, repairing conflict rather than avoiding it, and expressing gratitude and positive sentiments on a regular basis. “If you want to improve your life, invest in your relationships,” Radice-Vella says. 

Additionally, the study found that people who were more satisfied with their relationships in middle age were more likely to stay healthy later in life—demonstrating that those relationships can make a difference over time. “This is especially important because society often places a lot of emphasis on becoming financially successful, landing the ‘perfect job,’ or, in today’s digital age, building a personal brand and gaining recognition,” Vejar says. “While these goals can be meaningful, the study suggests that investing time and energy into strong relationships may have an even greater impact on long-term health and happiness.”

Read the original article on Real Simple

Monday, March 16, 2026

Who’s in Your 5? Scientists Say the Friends Closest to You Are the Ones That Help You Live Longer by Super Age

 Getting divorced helped this tremendously. I think I can consider 8 persons close friends, one going back to first grade. I'm expected to be the one turning the lights out, but I'll be sharing that last bottle of Green Spot before we all are too incapacitated to enjoy it. I'm easily going to hit 100.

Who’s in Your 5? Scientists Say the Friends Closest to You Are the Ones That Help You Live Longer


Wednesday, March 11, 2026

Negative social ties as emerging risk factors for accelerated aging, inflammation, and multimorbidity

 

Well, at age 50 I had my stroke and the result of that is making me happy for the rest of my life.  Got divorced at age 58, fired at age 56. All leading to moving to Michigan and finding lots of new friendships.


(Life is definitely better as I age, I got divorced enhancing my happiness immeasurably. I'm retired and comfortably well off. And healthy as I can be post stroke. I'm going to live a long time yet.)

Negative social ties as emerging risk factors for accelerated aging, inflammation, and multimorbidity

Edited by James W. Moody, Duke University, Durham, NC; received June 27, 2025; accepted January 22, 2026 by Editorial Board Member Mark Granovetter
February 18, 2026
123 (8) e2515331123

Social relationships are fundamental to human health, yet research has focused primarily on their supportive dimensions. We investigate the role of “hasslers,” people in one’s close social networks who create problems or make life more difficult, finding that these negative ties are not rare, disproportionately experienced by individuals facing greater social and health vulnerabilities, and consequential for aging. Each additional hassler is associated with faster biological aging, with especially pronounced effects when the hassler is a family member. These findings identify negative social ties as chronic stressors that shape aging trajectories and underscore the need for interventions that reduce harmful social exposures to promote healthier aging.

Abstract

Negative social ties, or “hasslers,” are pervasive yet understudied components of social networks that may accelerate biological aging and morbidity. Using ego-centric network data and DNA methylation-based biological aging clocks (i.e., DunedinPACE and age-accelerated GrimAge2) from saliva from a state representative probability sample in Indiana, we examine how negative social ties are associated with accelerated biological aging and a broad range of health outcomes, including inflammation and multimorbidity. Negative relationships are not rare within close relationships, as nearly 30% of individuals report having at least one hassler in their network. These hasslers tend to occupy peripheral network positions and are more likely to be connected through weak, uniplex ties. Importantly, exposure to negative social ties follows patterns of social and health vulnerability, with women, daily smokers, people in poorer health, and those with adverse childhood experiences more likely to report having hasslers in their networks. Having more hasslers is associated with accelerated biological aging in both rate and cumulative burden: Each additional hassler corresponds to approximately 1.5% faster pace of aging and roughly 9 mo older biological age. Moreover, not all hasslers exert the same influence; kin and nonkin hasslers show detrimental associations, whereas spouse hasslers do not. Finally, a greater number of hasslers is associated with multiple adverse health outcomes beyond epigenetic aging. These findings together highlight the critical role of negative social ties in biological aging as chronic stressors and the need for interventions that reduce harmful social exposures to promote healthier aging trajectories.

Sunday, March 8, 2026

Why Your Healthspan Depends on Your Nervous System’s Ability to Weather Storms by Super Age

 My resilience is excellent.

Well, at age 50 I had my stroke and the result of that is making me happy for the rest of my life.  Got divorced at age 58, fired at age 56. All leading to moving to Michigan and finding lots of new friendships.


(Life is definitely better as I age, I got divorced enhancing my happiness immeasurably. I'm retired and comfortably well off. And healthy as I can be post stroke. I'm going to live a long time yet.)

Why Your Healthspan Depends on Your Nervous System’s Ability to Weather Storms

This line is key; Stress 
[ri-zil-yuhns]nounThe ability to recover quickly from stress or setbacks.Learn More is a true barometer of emotional health and [lon-jev-i-tee]nounLiving a long life; influenced by genetics, environment, and lifestyle.Learn More.

Wednesday, October 29, 2025

11 Signs You Might Be Headed For a Heart Attack

 Stroke probably also falls into this.

11 Signs You Might Be Headed For a Heart Attack

1.  You get angry over the littlest things

Tend to morph into the Incredible Hulk when you’re upset? Those fiery emotions may increase your risk for a heart attack, according to research published in 2015 in the European Heart Journal.

Researchers at the University of Australia questioned 313 patients who had  suspected heart attacks about their anger levels before the onset of symptoms. They found that patients were 8.5 times more likely to have a heart attack in the two hours following an intense outburst of anger, defined as “very angry, body tense, clenching fists or teeth” compared with other times when they were less angry.

The findings suggest that if you have an episode of intense anger, it could increase your risk of heart attack in the subsequent hours. Here are the 9 best ways to control your anger and avoid getting to that point.

(I'm incredibly calm all the time, don't get flustered about anything.)

2.  You spend most of your time in front of a screen©Maskot/Getty Images

Yes, that includes working on your computer. A study published in the Journal of the American College of Cardiology in 2011 found that people who watch TV or work on a computer for four or more hours a day have more than double the risk of a cardiovascular disease event, like a heart attack, than those who spend less than two hours looking at a screen.

Long periods of sitting deplete the body’s supply of lipoprotein lipase, an enzyme that breaks down fat and prevents clogged arteries. If you spend most of your day plopped behind a desk, take a brief walk after every 20 minutes or try a standing desk. You can burn 30 percent more calories when you stand than when you sit. (Don't miss these 15 doctor-approved tips to prevent heart disease.)

(Yeah, doing this blog and my brain games is about 4-5 hours per day; not worried, my outdoor walking keeps me moving. And pee and water/coffee breaks mean doing steps in my 4 level condo, so moving quite regularly.)

3.  You log less than six hours of sleep each night©fizkes/Getty Images

Many adults struggle to get the recommended seven to nine hours of sleep each night, but consistently missing that mark could be bad for your heart. A study published in the Scandinavian Journal of Work, Environment & Health found that Japanese men who got less than six hours of sleep were five times more likely to have a heart attack than men who slept seven or eight hours a night. Don't miss what causes heart disease and how you can prevent it.

(Usually about 7 hours a night, starting at 2-3am. It's great being retired, getting up late is not a problem.

Reading in these 11 posts seems to consider napping very beneficial until you get longer than an hour.

4.  You live in a smoggy area©Maik Mitschke / EyeEm/Getty Images

Smog is just as bad for your heart as it is for your lungs. For a 2016 study published in Environment International, researchers used hourly air pollution measurements in South Boston to determine how exposure to particulate matter (small combustion particles that come from fuel burning and vehicle emissions) affected patients in this area who had heart attacks.

They found that exposure to high concentrations of air pollution increased the likelihood of a heart attack by 48 percent in the two hours before patients first experienced heart attack symptoms. The risk went up to 69 percent when people were exposed to high levels of air pollution for 24 hours before the onset of symptoms. (Here are 9 more things you should know about heart attacks before you have one.)

(Nope.)

5.  It’s daylight saving time©SrdjanPav/Getty Images

Several studies have found that the risk of heart attack goes up the first few days after daylight saving time starts, reports the American Heart Association. One study by Swedish researchers found about a 6.7 percent greater risk of a heart attack in the first three days after we spring forward. U.S. researchers tracked hospital records and found a 24 percent increase in heart attacks on the Monday after the spring time change. The risk slowly dropped the rest of the week.

Since the total heart attack counts for those weeks were not drastically different from other weeks, researchers determined that the time changes didn’t necessarily make the heart attacks happen, but rather made them likely to occur sooner than they otherwise would have. This is probably due to disrupted sleep-wake cycles and increased stress at the start of a new week of work.

(Being retired means this really has no effect on me at all.)

6.  You’re divorced©simarik/Getty Images

Divorce can cause literal heartache and be a heart attack risk factor. Researchers at the Duke University School of Medicine conducted an 18-year-study of nearly 16,000 men and women between the ages of 45 and 80 who had been married at least once. Every two years, researchers assessed the participants’ marital status and overall health.

Divorced women were 25 percent more likely to have a heart attack than those who stayed married. Women who had two or more divorces were 77 percent more likely to have a heart attack.

As for the men, the risk of heart attack stayed the same regardless of whether they were married or divorced—at first. But if they divorced at least twice, their heart attack risk increased by 30 percent.

(Very happily divorced! 

 I'm sure my divorce vastly improved my chances of not getting dementia. My social connections have exploded since then. My epigenetic aging was vastly improved by getting divorced. 

My story; I would still be leading a life of quiet desperation.

Why my stroke was the best thing to ever happen to me)

7.  You live in an area with extreme temperatures©Jeff Greenough/Getty Images

Studies show that both extreme cold and extreme heat can put people at risk for heart attacks. Using data from cardiac patients in the Worcester Heart Attack Study, a study in the journal Epidemiology found that exposure to temperatures lower than 17 degrees F in the two days prior to a heart attack increased patients’ risk by 36 percent.

On the other end of the spectrum, British researchers found that once the temperature reaches 68 degrees F, each increase of 1.8 degree F increased the risk of heart attack by 2 percent over the next one to six hours. On the first day of a hot spell, that risk jumps up to 6.5 percent per 1.8 degree F increase.

(Central Michigan; while summers can get in the 90's, winters have definitely wimped out. In the 13 years living here, maybe 1 year the ground actually froze. I barely ever wear my heaviest winter coat. And with a condo, no snow shoveling or lawn work.)

8.  You lived through a natural disaster©Stocktrek Images/Getty Images

Having a hurricane or earthquake devastate your hometown not only affects you mentally and emotionally but physically as well. Researchers at Tulane Medical Center in New Orleans studied the number of patients that were admitted with heart-related problems in the years after Hurricane Katrina hit the area in 2005.

They found that the number of people admitted to the hospital for heart attacks increased three-fold in the 10 years after Katrina, compared to the number of admissions in 2003 and 2004. Patients were also more likely to have heart attack risk factors after the hurricane, including high blood pressure, coronary artery disease, and diabetes.

(Nope, never got close to being in a tornado.)

9.  You didn't go to college©Sengchoy Inthachack / EyeEm/Getty Images

The four or more years you spend in college may be good for more than a diploma. A study published in the International Journal for Equity in Health analyzed data from more than 267,000 Australian men and women.

The results showed that people with no certifications or degrees were more than twice at risk of a heart attack compared to those with a university degree or higher. Bottom line: The more time you spend in school, the lower your risk for a heart attack.

(Bachelor degrees in Data Processing and Accounting. Got within two courses of a master's in finance.)

10.  You got the flu©PixelsEffect/Getty Images

The American College of Cardiology has long recommended that those with heart disease get annual flu shots, but research shows just how important that shot is.

A 2018 study in the New England Journal of Medicine looked at 364 people hospitalized for heart attacks and found that they were six times more likely to have a heart attack in the week after being infected with the flu.

If you're feeling under the weather, look out for these 7 silent signs you're having a heart attack.

(Have regularly gotten flu shots for the last 20 years. The last time I remember getting the flu was probably 35 years ago.)

11.  Your mother had a heart attack©ER Productions Limited/Getty Images

Or maybe it was your father, or grandparent, or siblings. No matter which relative it was, the American Heart Association says that heart disease and risk factors for heart disease are strongly linked to family history.

There are at least 67 sites in the DNA sequence, or variants, that can increase your risk of a heart attack. Each of these variants raises your risk of cardiovascular disease by about 10 percent. But if you have more variants, your risk adds up.

The good news is, having a family history of heart attacks doesn't guarantee you will have one. Actively maintaining a healthy lifestyle can lower your overall risk. (Start with these 30 proven ways to reduce your risk of heart disease.)

(One grandparent died of a heart attack, one died of a stroke. Dad died of Parkinsons and dementia at 91. Mom still living alone at 96. I'm going to easily break 100 if I'm not too wild in my extracurricular activities. I had my stroke at age 50, so got that out of the way early.)


Thursday, June 5, 2025

Mentally Resilient People Live Longer, Study Suggests — Try These Tips to Boost Your Coping Skills

 I think my resilience is quite impressive.

 A researcher asked me where my resilience came from a few years ago. I had no answer, but this probably explains it.

Your Mindset Shapes Your Life – For Better or Worse by Debbie Hampton

I haven't been depressed a day in my life, I roll with the punches; stroke, getting fired, divorce, moving to a new state.

I must have a lot of positive affectivity since I haven't been depressed a day in my life even with stroke, getting fired and divorced in a span of 8 years.

The latest here:

Mentally Resilient People Live Longer, Study Suggests — Try These Tips to Boost Your Coping Skills

When faced with a challenging circumstance, there are two ways to respond: smile serenely and say, “bring it on,” or throw your hands up and yell, “I can’t cope!” 

All right, so maybe a middle ground exists, but unless you’re a zen master, you’ve probably experienced that second reaction at some point in time. Thankfully, taking things in stride is a skill that can be developed and improved — and a new large-scale study is highlighting just how beneficial it is for overall health. 

Published in the journal BMJ Mental Health, the research found that being better able to cope with difficult life circumstances was linked to a lower risk of death from all causes in older adults. The findings were derived by analyzing data from the Health and Retirement Study, a long-term survey of Americans ages 50 and over. 

That study began in 1992, and individuals were monitored every two years thereafter, with information collected on their economic, health, marital, and family statuses. For the newly published paper, researchers drew on data from 2006-2008, when questions regarding mental resilience were first introduced. 

A total of 10,569 participants were involved in the final analysis, and were tracked until May 2021 or their death, whichever came first. The average age of this subset was 66, and 59% of the subjects were women.  

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Resilience scores were determined through a self-assessment of qualities like perseverance, calmness, a sense of purpose, self-reliance, and the recognition that certain experiences must be faced alone. Those who scored higher on the scale had a lower risk of all-cause mortality by as much as 38% compared to those who scored the lowest. 

“Various factors, including but not limited to meaning in life, positive emotions, self-rated health, and satisfaction with social support, have been identified as potential influences on psychological resilience,” the study authors wrote. “Triggering these positive emotions may enhance the protective effects of psychological resilience and mitigate the negative impact of accumulated adversity on mental health in adults.” 

They added: “The findings underscore the potential effectiveness of interventions aimed at promoting psychological resilience in order to mitigate mortality risks.”

So how do you improve your coping skills?

Dilok Klaisataporn/ iStock

Per Verywell Mind, two of the main types of coping are problem-based coping and emotion-based coping. “Problem-based coping skills focus on changing the situation, while emotional-based coping skills are centered on changing how you feel,” writes licensed clinical social worker Amy Morin. 

Problem-based coping tactics:

Reach out to a friend or a professional to help you work through the issue

Make a to-do list to break down a project into more achievable tasks

Distance yourself from the stressful situation

Practice time-management techniques if you’re feeling overwhelmed by a project

Set and maintain healthy boundaries with other people and your commitments

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Emotion-based coping tactics:

Focus on another activity to take your mind off the issue causing you stress

Engage in an enjoyable hobby

Practice self-care to feel better in the moment and beyond

Exercise or go for a walk

Try deep breathing, meditation, and other relaxation techniques

The more often you implement these tactics, the more natural they’ll become. Learn about other types of coping skills and strategies.

Friday, January 24, 2025

Odds of late-life stroke higher for those who experienced parental divorce in childhood

 You described a problem. WHAT IS THE PREVENTION SOLUTION? Oh, you incompetently provided nothing? Good to know you'll be fired soon!

Odds of late-life stroke higher for those who experienced parental divorce in childhood

Key takeaways:

  • Men had a 1.47 times greater risk of later-life stroke vs. women.
  • Odds of stroke were higher for those aged 80 years and older compared with individuals aged 65 to 69 years.

The odds for stroke in older adults was significantly higher for those who experienced parental divorce by their 18th birthday compared to those who did not, and higher for those of an older age, data show.

“Recent research suggests that adverse childhood experiences increase the risk of stroke in adulthood,” Esme Fuller-Thomson, PhD, professor and director of the Institute for Life Course and Aging, and Factor-Inwentash Faculty of Social Work at the University of Toronto, and colleagues wrote in PLoS One. “The number of [adverse childhood experiences] experienced increases the risk for negative health outcomes, including having a stroke.”Older man having stroke

New research determined higher odds of late-life stroke for those who experienced parental divorce in childhood, with similar high odds for men vs. women and those over 80. Image: Adobe Stock

Although studies have examined adverse childhood experiences (ACE) and chronic health outcomes including stroke, the body of research is limited on parental divorce and stroke correlations, Fuller-Thomson and colleagues wrote.

They sought to investigate associations between parental divorce in childhood and stroke incidence in older adults who did not experience child abuse, as well as to examine whether the correlation differed between men and women.

Their study culled data from the 2022 Behavioral Risk Factor Surveillance System to yield 13,205 U.S. adults 65 and older (56.6% female) who experienced neither physical nor sexual abuse as children and lived in eight states (Arkansas, Florida, Iowa, Nevada, North Dakota, South Dakota, Oregon and Virginia) where an optional self-report ACE survey module was answered that year.

The primary outcome for the study was parental divorce before the age of 18 among the eligible individuals, measured as a binary answer. The primary outcome variable was a binary answer to a question about diagnosis of stroke by a health care professional. Covariates for analysis included ACE, education level, household mental illness or substance use disorders, social support, health and diet-related behaviors and witnessed domestic violence. Age analysis was divided into four groups (65 to 69 years; 70 to 74 years; 75 to 79 years; 80 years and older) with sex of respondent also coded as a binary variable.

According to results, 7.3% of participants reported having stroke, while 13.9% reported that their parents had divorced before respondents’ 18th birthday.

When controlling for demographics, the odds for having a stroke later in life were 1.73 times higher for respondents who experienced parental divorce compared with those who did not (95% CI, 1.26-2.37). In a fully adjusted model, these individuals had 1.61 times higher odds for stroke than their counterparts (95% CI, 1.15-2.24).

The researchers also reported that the odds of late-life stroke were 1.74 times higher for those aged 75 to 79 years compared with those aged 65 to 69 years, and 2.11 times higher for those aged 80 years and older.

Data further showed that men had a 1.47 times greater risk of later-life stroke vs. women, and that those diagnosed with depression recorded a 1.76 times higher odds for stroke.

“It is extremely concerning that older adults who grew up in divorced families had 60% higher odds of stroke, even after excluding those who had been physically or sexually abused as children,” Fuller-Thomson said in a related release. “The magnitude of the association between parental divorce and stroke was comparable to well-established risk factors for stroke such as male gender and having diabetes.”

Reference:

Your stroke risk might be higher if your parents divorced during your childhood. https://www.eurekalert.org/news-releases/1070592. Published Jan. 22, 2025. Accessed Jan. 22, 2025.

Tuesday, June 27, 2023

Marital Histories and Associations With Later-Life Dementia and Mild Cognitive Impairment Risk in the HUNT4 70+ Study in Norway

 I'm sure my divorce vastly improved my chances of not getting dementia. My social connections have exploded since then.

Marital Histories and Associations With Later-Life Dementia and Mild Cognitive Impairment Risk in the HUNT4 70+ Study in Norway

Abstract

Objectives: Earlier studies suggest that being married in later life protects against dementia, and that being single in old age increases the risk of dementia. In this study, we examine midlife marital status trajectories and their association with dementia and mild cognitive impairment (MCI) at ages 70 plus using a large population based sample from Norway. 
 
Methods: Based on a general population sample linked to population registries (N = 8706), we used multinomial logistic regression to examine the associations between six types of marital trajectories (unmarried, continuously divorced, intermittently divorced, widowed, continuously married, intermittently married) between age 44 and 68 years from national registries and a clinical dementia or a MCI diagnosis after age 70. We estimated relative risk ratios (RRR) and used mediation analyses adjusting for education, number of children, smoking, hypertension, obesity, physical inactivity, diabetes, mental distress, and having no close friends in midlife. Inverse probability weighting and multiple imputations were applied. The population attributable fraction was estimated to assess the potential reduction in dementia cases due to marital histories. 
 
Results: Overall, 11.6% of the participants were diagnosed with dementia and 35.3% with MCI. Dementia prevalence was lowest among the continuously married (11.2%). Adjusting for confounders, the risk of dementia was higher for the unmarried (RRR = 1.73; 95% CI: 1.24, 2.40), continuously divorced (RRR = 1.66; 95% CI: 1.14, 2.43), and intermittently divorced (RRR = 1.50; 95% CI: 1.09, 2.06) compared to the continuously married. In general, marital trajectory was less associated with MCI than with dementia. In the counterfactual scenario, where all participants had the same risk of receiving a dementia diagnosis as the continuously married group, there would be 6.0% fewer dementia cases. Discussion: Our data confirm that staying married in midlife is associated with a lower risk of dementia and that divorced people account for a substantial share of dementia cases.

Saturday, March 11, 2023

Lifelong bachelorhood tied to mortality in men with heart failure

 FYI.  I probably would have been much healthier if I had stayed a bachelor. But then my happiness now is a direct result of my stroke, divorce and moving to Michigan.

Lifelong bachelorhood tied to mortality in men with heart failure

NEW ORLEANS — Lifelong bachelor status was associated with elevated risk for mortality in men, but not women, with heart failure, researchers reported at the American College of Cardiology Scientific Session.

“Our team was interested in the connection between a person’s life circumstances and the trajectory of heart disease,” Katarina Leyba, MD, a resident physician at the University of Colorado, told Healio. “As doctors, it is important that we see the whole patient in front of us and that we consider the context of a person’s life, not just their list of medications. So we asked the question: How does relationship status affect outcomes in patients with heart failure? As our population is getting older and living longer, it is important to determine how to best support patients through the aging process, and that might not be as easy as taking a pill. We need to take a personalized and holistic approach, especially for patients with a chronic disease like heart failure.”

Heart failure_Adobe Stock_192824687
Image: Adobe Stock.

Leyba and colleagues analyzed 94 patients from the MESA cohort study who were diagnosed with HF by year 10 of the study. They compared survival rates after HF diagnosis by sex and marital status during a mean follow-up period of 4.7 years.

The marital status categories were married, widowed, divorced, separated or never married.

Katarina Leyba, MD

In a univariate analysis, those who were never married had elevated risk for mortality compared with those who were married (HR = 1.6; P = .02), which remained after adjustment for age (adjusted HR = 1.61; P = .02).

Compared with married men, men who were never married had more than twofold elevated risk for mortality (HR = 2.16; P = .009), but there was no difference between never-married and married women, according to the researchers.

In a multivariate analysis, never being married was associated with elevated risk for mortality in men compared with being currently married (aHR = 2.21; P = .008), but being widowed (P = .28), being divorced (P = .86) and being separated (P = .8) were not, Leyba and colleagues found.

“We were not surprised to find that never having been married had an impact on the clinical course of men with heart failure,” Leyba told Healio. “What was surprising to us was that there were outcomes differences even amongst men who were currently unpartnered. While patients who were lifelong bachelors were at increased risk of dying compared to men who were currently married, patients who were widowed, divorced or separated were not. In contrast, women with heart failure who had never been married did not appear to be at higher risk of death than those who had. These findings suggest that marriage has some kind of beneficial effect(s) for men that helps them survive longer after developing heart failure. At present, we have not identified precisely what these effects are, but they could include health-seeking behaviors, socioeconomic and family support in older age, or differences in factors like frailty, nutrition and mood. The lack of difference in survival between women with different marital histories could indicate either that those same factors are not as clinically beneficial in women or possibly that there are few deficits in those traits that are impacted through marriage.”

She said that “relationship history appears to be much more important in men than women. Recognizing these factors may help us identify new interpersonal strategies that could help improve the ability of patients to cope with heart failure.”

Reference:

Saturday, January 28, 2023

Locus Control May Combat the Association Between Stress and Stroke Risk

 

Chronic stress(How am I going to recover?) is directly your doctor's responsibility to solve. THE SOLUTION IS 100% RECOVERY PROTOCOLS, not guidelines or the crapola saying; 'All strokes are different, all stroke recoveries are different'. If that saying comes out of your doctor's mouth, you don't have a functioning stroke doctor, fire them. 

My divorce and firing vastly improved my locus of control.

Locus Control May Combat the Association Between Stress and Stroke Risk

 A higher locus of control at work and home is tied to reduced psychosocial stress and a lower risk for stroke.

Increased locus of control at work and home is associated with a reduced risk for stroke, according to the findings of a case-control study published in JAMA Network Open.

An established and independent risk factor for acute stroke is self-reported psychosocial stress. Although there is an established risk factor between stress and poor outcomes, no effective interventions for preventing stress-associated outcomes have been identified. For the study, researchers sought to assess whether psychosocial stress is associated with an increased risk for acute stroke, and whether locus control is an effect modifier.

They evaluated data from INTERSTROKE, which was an international case-control study of stroke risk that included 32 countries in Asia, North and South Americas, Europe, Australia, the Middle East and Africa. Between 2007 and 2015, 13,462 patients with stroke and 13,488 matched control individuals were recruited in 32 countries. In this analysis, psychosocial stress outcomes were evaluated among the 13,350 individuals with stroke and 13,462 control individuals who had sufficient data.

The individuals with stroke and control individuals were mean age, 62.2 (standard deviation [SD], 13.6) and 61.3 (SD, 13.3) years and 59.6% and 59.6% were men, respectively.

The researchers measured psychosocial stress and occurrence of stressful life events within the preceding year by using a standardized questionnaire of self-reported stress at home and work.

[H]igher locus of control is associated with lower risk of stroke and may be an important effect modifier of the risk associated with psychosocial stress.

Among stroke cases, 2745 individuals reported periods of stress or permanent stress. The individuals who reported stressed were younger, more educated, more worked as a professional or skilled laborer, were sedentary at work, consumed alcohol, and had a higher body mass index (BMI) compared with those who were not stressed (all P <.001). Among control individuals, 1933 reported stress and similar trends were observed compared with non-stressed control individuals (all P <.001).

Home stress was associated with increased risk for stroke (odds ratio [OR], 1.95), intracerebral hemorrhage (OR, 2.55), and ischemic stroke (OR, 1.82). Similarly, work stress associated with increased risk for stroke (OR, 2.70), intracerebral hemorrhage (OR, 5.20), and ischemic stroke (OR, 1.85) and life event stressors with higher risk for stroke (OR, 1.17).

Stratified by life stressors, major intrafamily conflict (OR, 1.77), death of a spouse (OR, 1.35), marital separation or divorce (OR, 1.33), and violence (OR, 1.26) increased stroke risk.

Higher locus of control at home was associated with reduced risk for stroke (OR, 0.73).

Among individuals with home stress, greater life control associated with lower stroke risk than low life control (P <.001). A similar pattern was observed for work stress (P =.008).

In subgroup analyses, global stress was not a significant risk factor for ischemic stroke among participants in Africa. The effect of intrafamily conflict and other stressful life events on stroke risk was stronger among men than women. Also, the effects of other stressors and business failure or loss of crop on stroke risk were stronger among individuals younger than 45 years of age compared with other age groups.

The major limitation of this analysis was that stress was self-reported and not objectively assessed.

The researchers noted that the findings of their study suggest that “higher locus of control is associated with lower risk of stroke and may be an important effect modifier of the risk associated with psychosocial stress.”

Additional study is needed into locus control to understand whether it may be a target for public health interventions.