Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label Hawthorne Effect. Show all posts
Showing posts with label Hawthorne Effect. Show all posts

Monday, May 4, 2026

Efficacy of radial shock wave therapy for ankle spasticity in patients with stroke within 3 months of onset: a prospective quasi-experimental study

So, still a failure; no cure for spasticity. The goal is to cure spasticity, not just reduce it.

When you are the 1 in 4 per WHO that has a stroke with spasticity, you'll want your spasticity cured. You better start solving that now.

Since you are using a subjective measurement scale(Modified Ashworth Scale) nothing here inspires any sort of confidence. In fact I would assume that the participants are using the Hawthorne effect to please the researchers. 

Efficacy of radial shock wave therapy for ankle spasticity in patients with stroke within 3 months of onset: a prospective quasi-experimental study

    We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

    Abstract

    Background

    Extracorporeal shock wave therapy (ESWT) is widely used to reduce poststroke spasticity (PSS). However, limited evidence exists regarding its efficacy in patients with stroke within 3 months of onset. Therefore, this study aimed to investigate the association between ESWT administered 1 to 3 months after stroke and changes in spasticity and joint mobility in patients with PSS.

    Methods

    Prospective quasi-experimental study. Fifty-two patients with PSS affecting the ankle joint were enrolled from March 2023 to March 2025, and allocated into three groups based on the time elapsed from stroke onset: 1, 2, or 3 months. All patients underwent radial ESWT to the gastrocnemius and soleus muscles once weekly for 3 consecutive weeks. Spasticity and joint mobility were evaluated using the Modified Ashworth Scale (MAS) and passive range of motion (PROM) measurements before and after each session, and at 1 and 5 weeks post-treatment.

    Results

    Except for the MAS score obtained after the first session, significant immediate reductions in the MAS scores and PROM measurements were observed after all shock wave therapy sessions. Compared to baseline, cumulative changes were greatest after the third session, with a mean reduction of 0.6 points in the MAS score and a 6.4° increase in the PROM. These changes were maintained for 5 weeks. No serious adverse events related to shock wave therapy were reported.

    Conclusions

    ESWT during the early subacute stage was associated with improvements(NOT GOOD ENOUGH!) in spasticity and joint mobility in patients with PSS. Repeated sessions showed greater cumulative changes compared with a single session.

    Trial registration UMIN-CTR000050477.

    Monday, August 25, 2025

    Assessment of the effects of rehabilitation in the area of hand function using a Biometrics device in people after stroke -a randomised controlled trial

    Additional therapy provides more recovery. It doesn't prove the Biometric device created that recovery. In fact I would assume that the participants are using the Hawthorne effect to please the researchers.

     Assessment of the effects of rehabilitation in the area of hand function using a Biometrics device in people after stroke -a randomised controlled trial


    Justyna  LeszczakJustyna Leszczak1*Bogumiła  PniakBogumiła Pniak1,2Grzegorz  GazdaGrzegorz Gazda2Agnieszka  GuzikAgnieszka Guzik1
    • 1Institute of Physiotherapy, Faculty of Health Sciences and Psychology, Collegium Medicum, University of Rzeszów, Rzeszów, Poland, Rzeszów, Poland
    • 2Excelsior Health and Rehabilitation Hospital, Iwonicz-Zdrój, Poland, Iwonicz Zdrój, Poland

    The final, formatted version of the article will be published soon.

      The aim of the study was to assess the effects of rehabilitation using the Biometrics device on the re-education of hand function in people in the late period after stroke patients. 

      Methods: 

      The data were collected from 1 August 2022 to 28 February 2023. The study was conducted among 120 people after stroke, who were randomly assigned to the test group (n=60) orand the control groups (n=60). Both groups were provided with a 3-weekThe rehabilitation program lasted 3 weeks and tookfor 2 hours a day for both groups. While tThe control group received traditional physiotherapy, t. The test group additionally underwent biofeedback training. The first eExaminations werewas performed on the first day and of rehabilitation, the second examination was performed on the finallast day of the 3-week intervention program (at discharge). The primary measurement included assessment of hand grip strength (key, three jaw chuck, tip-to-tip) using an electronic dynamometer and a Biometrics E-link pinchmeter. Secondary outcomes included hand motor function assessment, using the Fugl-Meyer Assessment-Hand Function scale, hand motor dexterity with the Box and Blocks test, hand grip functions according to the Frenchay scale, and functional fitness with the Barthel index. 

      Results: 

      In the test group, significant rehabilitation effects were observed for the assessment of grip strength, finger compression strength, manual hand dexterity, grip function and everyday activities of daily living (p<0.001; p=0.001), while in the control group results were improved for grip strength and finger compression strength (key and three-jaw chuck) of the right hand (p=0.012; p=0.017; p=0.001) and manual dexterity (p<0.001), motor abilities and daily activities of daily living (p<0.001).The study showed positive effects of hand function rehabilitation in chronic stroke patients in the late period in both groups. However, in the test group, which additionally underwent training that stimulated the central nervous system using the biofeedback method with the Biometrics device, better hand and finger grip function of the hand and fingers, as well as hand motor and manual function of the hand were noted.

      Keywords: Rehabilitation, Upper limb, Stroke, Do lewej, Bez punktorów lub numeracji -sformatowano: Czcionka: Kursywa Sformatowano: Wcięcie: Z lewej: 1, 27 cm, Bez punktorów lub numeracji

      Received: 08 Jun 2025; Accepted: 22 Aug 2025.

      Copyright: © 2025 Leszczak, Pniak, Gazda and Guzik. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

      * Correspondence: Justyna Leszczak, Institute of Physiotherapy, Faculty of Health Sciences and Psychology, Collegium Medicum, University of Rzeszów, Rzeszów, Poland, Rzeszów, Poland

      Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

      Saturday, September 14, 2024

      A systematic review of upper extremity outcome measures assessed in randomized controlled trials of post stroke upper extremity rehabilitation over time

       Yep, the standard outcome measure for all stroke interventions should be 100% recovery. Not this tyranny of low expectations your stroke medical 'professionals' are pushing on you because they are completely failing at their only job; 100% recovery for all!

      Send me hate mail on this: oc1dean@gmail.com. I'll print your complete statement with your name and my response in my blog. Or are you afraid to engage with my stroke-addled mind? Your patients need an explanation of why you aren't working on 100% recovery protocols.

      Why isn't your doctor solving stroke?

      Laziness? Incompetence? Or just don't care? NO leadership? NO strategy? Not my job? Not my Problem?

      A systematic review of upper extremity outcome measures assessed in randomized controlled trials of post stroke upper extremity rehabilitation over time

      Received 05 Jan 2024, Accepted 17 Aug 2024, Published online: 11 Sep 2024

      ABSTRACT

      Background

      The heterogeneity in outcome measures of post stroke rehabilitation trials suggests the need for consensus approach in stroke recovery measurement. To reach this aim, it is important to understand the past and current use of outcome measures in randomized control trials (RCTs) of stroke rehabilitation.

      Objective

      To systematically review RCTs of post stroke UE rehabilitation interventions to understand the use of UE outcome measures in research and their changes over time.

      Methods

      CINAHL, Embase, PubMed, Scopus and Web of Science were searched from 1960 to 1 April 2021. Studies were eligible for inclusion if they (1) were RCTs or crossovers published in English (2) ≥50% of participants were affected by stroke, 3) included adults ≥ 18 years old, and (4) applied an intervention to the hemiparetic UE as the primary objective of the study.

      Results

      1,276 RCTs met inclusion criteria, and 112 different outcome measures were identified. Outcome measures were classified according to the International Classification of Functioning, Disability and Health (ICF) framework. Outcome measures most frequently assessed body function and structure (n = 1,692), followed by activities (n = 1,572) and participation (n = 162). The most used outcome measures were the Fugl-Meyer Assessment (n = 619), the modified Ashworth Scale (n = 255), Action Research Arm Test (n = 211), Wolf Motor Function Test (n = 184), and Box and Block Test (n = 178).

      Using Fugl-Meyer for anything in stroke is the height of stupidity, nothing objective in it, so nothing is repeatable.

      Since you are using subjective measurement scales(Fugl-Meter and Modified Ashworth Scale) nothing here inspires any sort of confidence. In fact I would assume that the participants are using the Hawthorne effect to please the researchers.

       

       

      Conclusions

      Understanding the breadth of outcome measures that have been used over time emphasizes the need for proposed standardization of outcome measures but also the need to adjust and expand consensus recommendations based on past and ongoing research trends.

      Wednesday, August 19, 2020

      Effect of investigator observation on gait parameters in individuals with stroke

      Well at least you know this is the Hawthorne effect, but why you didn't put that in the title is beyond me. 

       Effect of investigator observation on gait parameters in individuals with stroke

      Journal of Biomechanics , Volume 100(109602)

      NARIC Accession Number: J84189.  What's this?
      ISSN: 0021-9290.
      Author(s): Ardestani, Marzieh M. ; Hornby, T. George.
      Project Number: H133B031127.
      Publication Year: 2020.
      Number of Pages: 7.
      Abstract: Study investigated whether testing conditions, specifically the presence of an observer, influences patient behaviors and clinical and biomechanical measures of walking function. This potential effect of observational awareness, also known as the Hawthorne effect, on spatiotemporal and biomechanical measures of locomotor function in individuals post-stroke has not been assessed previously. Fifteen ambulatory individuals with chronic stroke wore instrumented insoles and performed two separate normal-pace walking assessments, including unobserved conditions during which participants were unattended and unaware of data collection, and observed conditions with an investigator present. Gait analysis was conducted outside of a laboratory setting using instrumented insoles equipped with a three-dimensional accelerometer and pressure sensors which captured the spatiotemporal kinematics, vertical ground reaction forces and foot acceleration. Data were compared using paired comparisons, with subsequent correlation and stepwise regression analyses to explore potential associations between Hawthorne-induced changes in walking strategies, gait speed and locomotor performance (daily stepping). Except for cadence, other measures of spatiotemporal parameters and swing kinematics (acceleration) were not significantly different between observed vs unobserved conditions. However, analyses of ground reaction forces revealed significantly greater paretic limb loading and increases in weight bearing symmetry during observed versus unobserved conditions. This potential Hawthorne effect was greater in those with slower walking speeds and shorter stride lengths but was not related to daily stepping. The present findings suggest that biomechanical parameters of walking function may be related to the presence of an observer and highlight the need to separately measure locomotor capacity (gait speed) and performance (daily stepping).
      Descriptor Terms: AMBULATION, BIOENGINEERING, EVALUATION TECHNIQUES, MEASUREMENTS, MOTOR SKILLS, OUTCOMES, STROKE.


      Can this document be ordered through NARIC's document delivery service*?: Y.

      Citation: Ardestani, Marzieh M. , Hornby, T. George. (2020). Effect of investigator observation on gait parameters in individuals with stroke.  Journal of Biomechanics , 100(109602) Retrieved 8/18/2020, from REHABDATA database.

      Saturday, June 27, 2020

      Hyperbaric Oxygen and Focused Rehabilitation Program: A Feasibility Study in Improving Upper Limb Motor Function After Stroke

      Oh, come on. Do some research that is feasible and within the price range of most patients.  Did you account for the participants using the Hawthorne effect to please the researchers since they would know which group they were in?  Yes there are 5 within 90 minutes of me, I have never considered going to one.

       

      What is the typical cost of the treatment? Hard HBOT in a hyperbaric clinic typically costs $250 per session, or $10,000 for 40 sessions. Thus, the standard HBOT protocol costs $20,000 for 80 sessions. Since many people go on to do hundreds of sessions over a period of years, the costs can be very high.

      Hyperbaric Oxygen and Focused Rehabilitation Program: A Feasibility Study in Improving Upper Limb Motor Function After Stroke

      Simone Schiavo, Denyse Richardson, Daniel Santa Mina; ; , Stephanie Buryk-Iggers, Julie Uehling, Jo Carroll, Hance Clarke, Carine Djaiani, Maxim Gershinsky, Rita Katznelson
      Published on the web 23 June 2020.
      Received February 23, 2020.

      Applied Physiology, Nutrition, and Metabolism, https://doi.org/10.1139/apnm-2020-0124

      Abstract

      Neuroplasticity and recovery after stroke can be enhanced by a rehabilitation program pertinent to upper limb motor function exercise and mental imagery (EMI) as well as hyperbaric oxygen therapy (HBOT). We assessed the feasibility and safety of the combined approach utilizing both HBOT and EMI, and derived preliminary estimates of its efficacy. In this randomized controlled trial, twenty-seven patients with upper extremity hemiparesis 3-48 months after stroke were randomized to receive either a complementary rehabilitation program HBOT-EMI (intervention group), or EMI alone (control group). Feasibility and safety were assessed as total session attendance, duration of sessions, attrition rates, missing data, and intervention-related adverse events. Secondary clinical outcomes were assessed with both objective tools and self-reported measures at baseline, 8 weeks (end of treatment), and 12-weeks follow-up. Session attendance, duration and attrition rate did not differ between the groups; there were no serious adverse events. Compared to baseline, there were significant sustained improvements of objective and subjective outcomes’ measures in the intervention group, and a single improvement in an objective measure in the control group. Between-group outcome comparisons were not statistically significant. This study demonstrated that the combination HBOT-EMI was a safe and feasible approach in patients recovering from chronic stroke. There were also trends for improved motor function of the affected upper limb after the treatments. Registration-URL:https://www.clinicaltrials.com NCT02666469. NOVELTY: - HBOT combined with an upper limb exercise and mental imagery rehabilitation program is feasible and safe in chronic stroke patients. - This combined approach showed trends for improved functional recovery.

      Wednesday, June 3, 2020

      Use of real-time visual feedback during overground walking training on gait symmetry and velocity in patients with post-stroke hemiparesis: randomized controlled, single-blind study.

      These are high functioning patients already, stage IV and V and ability to walk 30 minutes at a time.  I have no understanding of real-time visual feedback.  In fact I would assume that the participants are using the Hawthorne effect to please the researchers since they would know which group they were in.

      Use of real-time visual feedback during overground walking training on gait symmetry and velocity in patients with post-stroke hemiparesis: randomized controlled, single-blind study.

      Abstract 


      This study aimed to determine the efficacy of using real-time visual feedback during overground walking training to improve walking function in patients with post-stroke hemiparesis. Twenty-four patients with post-stroke hemiparesis who were able to walk independently under less impact of synergy pattern on the affected lower limbs (Brunnstrom stage IV or V) were randomly assigned to either the experimental group or the control group. All subjects performed overground walking for 30 min, three times a week for 6 weeks, with real-time visual feedback (weight load to the affected lower limb) provided during training for subjects in the experimental group. Outcome measures comprised the timed up-and-go test and gait parameters (step length, stride length, single and double support times, step and stride length ratios, and single support time ratio). In between-group comparison, the changes between pre-test and post-test scores in all parameters were significantly greater in the experimental group than in the control group (P < 0.05), except for double support time and step length ratio. Furthermore, post-test values of all parameters were significantly more improved in the experimental group than in the control group (P < 0.05). Our findings suggest that real-time visual feedback may be an advantageous therapeutic adjunct to reinforce the effects of overground walking training in patients with post-stroke hemiparesis.

      Sunday, May 24, 2020

      Conflicting results of robot-assisted versus usual gait training during postacute rehabilitation of stroke patients: a randomized clinical trial

      It has been 5 years, your doctor needs to find OUT EXACTLY WHAT THE REHAB FOR GAIT TRAINING SHOULD LOOK LIKE. Bad research, using Bobath as the conventional treatment even though proven not to work since 2003.  The mentors and senior researchers need to be fired for that reason alone.

      Physiotherapy Based on the Bobath(NDT) Concept for Adults with Post-Stroke Hemiplegia: A Review of Effectiveness Studies; 2003

       The latest here:

      Conflicting results of robot-assisted versus usual gait training during postacute rehabilitation of stroke patients: a randomized clinical trial

      Received 12 June 2015, Accepted 16 September 2015
      Giovanni Taveggiaa,b, Alberto Borbonic, Chiara Muléa,b, Jorge H. Villafañed and Stefano Negrinid,e
      Correspondence to Giovanni Taveggia, Faccanoni Hospital, Sarnico, Italy; e-mail: giovannitaveggia@habilitasarnico.it

      Robot gait training has the potential to increase the effectiveness of walking therapy. Clinical outcomes after robotic training are often not superior to conventional therapy. We evaluated the effectiveness of a robot training compared with a usual gait training physiotherapy during a standardized rehabilitation protocol in inpatient participants with post stroke hemiparesis. This was a randomized double-blind clinical trial in a post acute physical and rehabilitation medicine hospital. Twenty-eight patients, 39.3% women (72±6 years), with hemiparesis (<6 months after stroke) receiving a conventional treatment according to the Bobath approach were assigned randomly to an experimental or a control intervention of robot gait training to improve walking (five sessions a week for 5 weeks). Outcome measures included the 6-min walk test, the 10m walk test, Functional Independence Measure, SF-36 physical functioning and the Tinetti scale. Outcomes were collected at baseline, immediately following the intervention period and 3 months following the end of the intervention. The experimental group showed a significant increase in functional independence and gait speed (10m walk test) at the end of the treatment and follow-up, higher than the
      minimal detectable change. The control group showed a significant increase in the gait endurance (6-min walk test) at the follow-up, higher than the minimal detectable change. Both treatments were effective in the improvement of gait performances, although the statistical analysis of functional independence showed a significant improvement in the experimental group, indicating possible advantages during generic activities of daily living compared with overground treatment.
      (In fact I would assume that the participants are using the Hawthorne effect to please the researchers.)


      Introduction 

      Stroke is the leading cause of death and of serious longterm disability in adults; 3 months after stroke, 20% of individuals remain wheelchair bound and 70% walk at reduced velocity (Sakuma et al., 2014). Improvement in walking after stroke is a priority for many patients and is one of the most frequently demanded goals of rehabilitation, and interventions that effectively enhance locomotor function are essential to improve quality of life of many stroke survivors and their families (Maclean et al., 2000). Stroke patients, when they regain ambulatory function, walk with a typically asymmetrical gait pattern, slow and metabolically inefficient. These characteristics are associated with difficulty advancing the paretic limb and bearing weight through the more affected limb, leading to instability and increased risk of falls. Muscle weakness,
      muscle tonus, muscle disuse, balance and reduced cardiorespiratory capacity contribute towards decrease walking velocity and endurance and finally worsen the disability (Perry et al., 1995). To restore gait, modern concepts of rehabilitation favour a repetitive task-specific approach (French et al., 2007). In the past 10 years, it has also been shown that higher intensities of walking practice result in better outcomes for individuals after stroke (Van Peppen et al., 2004). For gait training, it is important to walk repetitively in a natural gait similar to overground gait (Dobkin, 2004), and with proprioceptive and exteroceptive feedback (Barbeau, 2003), which recreates conditions favourable to motor learning. In recent years, as an adjunct to overground gait training, treadmill training has been introduced for the rehabilitation of individuals after stroke (Moseley et al., 2005). Treadmill training with and without body weight support enables the repetitive practice of a generic gait cycle (Taveggia et al., 2014). Manually assisted Body-Weight
      This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NCND),whereit is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.

      Supported Treadmill Training is a contemporary approach to gait rehabilitation after stroke, whereas when a patient walks on a treadmill, the therapists manually facilitate hemiparetic limb and trunk control in an effort to normalize upright and reciprocal walk and dynamic postural control. The advantages of this approach are that reduced motion ability is required to start locomotion; thus, early poststroke training effects can be observed in overground gait, that is, gait symmetry, speed and endurance as well as motor impairment and balance scores (McCain et al., 2008). A disadvantage of Body-Weight Supported Treadmill Training might be the effort required by therapists to set the paretic limbs and to control weight shift, thereby possibly limiting the duration of the active therapy, especially in more impaired patients. Automated electromechanical gait machines for automated assistive walking training were developed to reduce dependence on therapists and can be differentiated into end effector and exoskeleton devices. Selection of patients and an early application of robot aided rehabilitation are considered a prerequisite to achieve the best results. However, the impact of other factors such as the type of technology in relationship to the patient’s selection as well as the duration/intensity of the robot-aided treatment has not received more attention (Mehrholz et al., 2013). The main aim of the present study is to compare the effects of electromechanical assisted gait training after stroke and overground conventional physical therapy in a double-blind research for functional gait recovery of individuals unable to walk independently.

      Thursday, December 26, 2019

      A Case Series Clinical Trial of a Novel Approach Using Augmented Reality That Inspires Self-body Cognition in Patients With Stroke: Effects on Motor Function and Resting-State Brain Functional Connectivity

      Since you are using subjective measurement scales(Fugl-Meter and Modified Ashworth Scale) nothing here inspires any sort of confidence. In fact I would assume that the participants are using the Hawthorne effect to please the researchers.

      A Case Series Clinical Trial of a Novel Approach Using Augmented Reality That Inspires Self-body Cognition in Patients With Stroke: Effects on Motor Function and Resting-State Brain Functional Connectivity


      Fuminari Kaneko1,2*, Keiichiro Shindo1,2, Masaki Yoneta1,2,3, Megumi Okawada1,2,3, Kazuto Akaboshi1,2,3 and Meigen Liu1
      • 1Department of Rehabilitation Medicine, Keio University School of Medicine, Tokyo, Japan
      • 2Department of Rehabilitation, Shonan Keiiku Hospital, Fujisawa, Japan
      • 3Hokuto Social Medical Corporation, Obihiro, Japan
      Barring a few studies, there are not enough established treatments to improve upper limb motor function in patients with severe impairments due to chronic stroke. This study aimed to clarify the effect of the kinesthetic perceptional illusion induced by visual stimulation (KINVIS) on upper limb motor function and the relationship between motor function and resting-state brain networks. Eleven patients with severe paralysis of upper limb motor function in the chronic phase (seven men and four women; age: 54.7 ± 10.8 years; 44.0 ± 29.0 months post-stroke) participated in the study. Patients underwent an intervention consisting of therapy using KINVIS and conventional therapeutic exercise (TherEX) for 10 days. Our originally developed KiNvis™ system was applied to induce KINVIS while watching the movement of the artificial hand. Clinical outcomes were examined to evaluate motor functions and resting-state brain functional connectivity (rsFC) by analyzing blood-oxygen-level-dependent (BOLD) signals measured using functional magnetic resonance imaging (fMRI). The outcomes of motor function (Fugle-Meyer Assessment, FMA) and spasticity (Modified Ashworth Scale, MAS) significantly improved after the intervention. The improvement in MAS scores for the fingers and the wrist flexors reached a minimum of clinically important differences. Before the intervention, strong and significant negative correlations between the motor functions and rsFC of the inferior parietal lobule (IPL) and premotor cortex (PMd) in the unaffected hemisphere was demonstrated. These strong correlations were disappeared after the intervention. A negative and strong correlation between the motor function and rsFC of the bilateral inferior parietal sulcus (IPS) significantly changed to strong and positive correlation after the intervention. These results may suggest that the combination approach of KINVIS therapy and TherEX improved motor functions and decreased spasticity in the paralyzed upper extremity after stroke in the chronic phase, possibly indicating the contribution of embodied-visual stimulation. The rsFC for the interhemispheric IPS and intrahemispheric IPL and PMd may be a possible regulatory factor for improving motor function and spasticity.
      Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT01274117.

      Sunday, December 22, 2019

      Intensive upper limb neurorehabilitation in chronic stroke: outcomes from the Queen Square programme

      What blithering stupidity, jumping to conclusions, maybe you might think this was spontaneous recovery, the placebo effect, the Hawthorne effect. Using any of your measurement modalities are not objective so, you don't even know what occurred. 

      None of the four outcome measurement tools are objective so absolutely nothing here is repeatable on demand. 

      But enough big words and jargon were used so it must be important and survivors shouldn't question our bettors. 

      Intensive upper limb neurorehabilitation in chronic stroke: outcomes from the Queen Square programme

      1. Nick S Ward1,2,3,
      2. Fran Brander2,3,
      3. Kate Kelly2,3

      Abstract

      Objective Persistent difficulty in using the upper limb remains a major contributor to physical disability post-stroke. There is a nihilistic view about what clinically relevant changes are possible after the early post-stroke phase. The Queen Square Upper Limb Neurorehabilitation programme delivers high-quality, high-dose, high-intensity upper limb neurorehabilitation during a 3-week (90 hours) programme. Here, we report clinical changes made by the chronic stroke patients treated on the programme, factors that might predict responsiveness to therapy and the relationship between changes in impairment and activity.
      Methods Upper limb impairment and activity were assessed on admission, discharge, 6 weeks and 6 months after treatment, with modified upper limb Fugl-Meyer (FM-UL, max-54), Action Research Arm Test (ARAT, max-57) and Chedoke Arm and Hand Activity Inventory (CAHAI, max-91). Patient-reported outcome measures were recorded with the Arm Activity Measure (ArmA) parts A (0–32) and B (0–52), where lower scores are better.
      Results 224 patients (median time post-stroke 18 months) completed the 6-month programme. Median scores on admission were as follows: FM-UL = 26 (IQR 16–37), ARAT=18 (IQR 7–33), CAHAI=40 (28-55), ArmA-A=8 (IQR 4.5–12) and ArmA-B=38 (IQR 24–46). The median scores 6 months after the programme were as follows: FM-UL=37 (IQR 24–48), ARAT=27 (IQR 12–45), CAHAI=52 (IQR 35–77), ArmA-A=3 (IQR 1–6.5) and ArmA-B=19 (IQR 8.5–32). We found no predictors of treatment response beyond admission scores.
      Conclusion With intensive upper limb rehabilitation, chronic stroke patients can change by clinically important differences in measures of impairment and activity. Crucially, clinical gains continued during the 6-month follow-up period.

      Saturday, December 7, 2019

      Comparative Study to Evaluate the Effectiveness of Vestibular Rehabilitation Therapy versus Dual Task Training on Balance and Gait in Posterior Cerebral Artery (PCA) Stroke

      So VRT is more effective but you didn't write up a protocol on it, so completely useless.  Didn't your mentors and senior researchers tell you the only goal of stroke research is rehab protocols leading to 100% recovery?  They were that incompetent? Did you account for this possibly being the Hawthorne effect?

      Comparative Study to Evaluate the Effectiveness of Vestibular Rehabilitation Therapy versus Dual Task Training on Balance and Gait in Posterior Cerebral Artery (PCA) Stroke

      • Source: Journal of Clinical & Diagnostic Research . Nov2019, Vol. 13 Issue 11, p10-17. 8p.
      • Author(s): SALEEM, SANA; ARORA, BHARTI; CHAUHAN, PRIYA

      • Abstract: 

      • Introduction: Vestibular Rehabilitation Therapy (VRT) and Dual Task (DT) training are rehabilitation approaches increasingly used in the care of stroke patients to improve balance and gait, although no comparative evidence has been provided for their efficacy. Aim: The study was aimed to compare the effectiveness of vestibular rehabilitation therapy versus dual task training on balance and gait in posterior cerebral artery stroke. Materials and Methods: A total of 30 subjects i.e., subacute Posterior Cerebral Arterystroke individuals were randomly assigned into 2 groups, group A Vestibular Rehabilitation with Conventional Therapy (n=15) and group B DT training (n=15). Each group received treatment for 45 minutes in a day, 3 times in a week for 4 weeks. Both the groups A and B were also given Conventional Physiotherapy treatment comprising of stretching, strengthening and stability exercises, over the period for 5 days for 4 weeks. Participants were assisted with Wisconsin Gait Scale (WGS) to assess the performance of gait and Mini-BEST test to assess the balance. Mean change score were calculated as the difference between post and pre-test scores and an independent t-test was used to test the difference in the changed scores between two groups. Paired t-test was used to analyse within group differences. A level of significance was set at p≤0.05. Results: The comparison of post intervention scores of Mini- BESTest between Group A and Group B showed significant difference (t-value=2.577, p-value=0.018). The comparison of post intervention scores of WGS between Group A and Group B showed significant difference (t-value= -2.356, p-value=0.028). So, result showed that Group A (Vestibular Rehabilitation) was more significant as compared to Group B (DT training) in both Mini-BESTest and WGS. 
      • Conclusion: The result of this study is encouraging to use VRT as a part of rehabilitation protocol by alleviating their gait disturbances, improving balance and gaining confidence of walking with PCA stroke patients as compared with DT Training.
      • Copyright of Journal of Clinical & Diagnostic Research is the property of JCDR Research & Publications Private Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.


      Thursday, November 28, 2019

      Stroke Care 2 Stroke rehabilitation


      I have seen nothing that supports that multidisciplinary units are doing anything other than taking credit for spontaneous recovery and

      the Hawthorne effect.

      Other than that this is all generalities, so useless. 


      Stroke Care 2 Stroke rehabilitation



      Series
      www.thelancet.com

      Vol 377 May 14, 2011
      1693
      Lancet
       2011; 377: 1693–702
      See
      Editorial
      page 1625See
      World Report
       page 1639This is the second in a
      Series
       of two papers about stroke care
      Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, Glasgow, UK
       (Prof P Langhorne PhD)
      ; Stroke Division, Florey Neuroscience Institutes, Melbourne, VIC, Australia
      (Prof J Bernhardt PhD)
      ; La Trobe University, Bundoora, VIC, Australia
       (J Bernhardt)
      ; Department of Rehabilitation Medicine, Research Institute MOVE, VU University Medical Centre, Amsterdam, Netherlands
      (G Kwakkel PhD)
      ; and Rudolf Magnus Institute, University Medical Centre Utrecht, Utrecht, Netherlands
      (G Kwakkel)Correspondence to:Prof Peter Langhorne, Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, Level 4, Walton Building, Royal Infirmary, Glasgow G4 0SF, UK
      peter.langhorne@glasgow.ac.uk
      Stroke Care 2Stroke rehabilitation
      Peter Langhorne, Julie Bernhardt, Gert Kwakkel
      Stroke is a common, serious, and disabling global health-care problem, and rehabilitation is a major part of patient care. There is evidence to support rehabilitation in well coordinated multidisciplinary stroke units or through provision of early supported provision of discharge teams. Potentially beneficial treatment options for motor recovery of the arm include constraint-induced movement therapy and robotics. Promising interventions that could be beneficial to improve aspects of gait include fitness training, high-intensity therapy, and repetitive-task training. Repetitive-task training might also improve transfer functions. Occupational therapy can improve activities of daily living; however, information about the clinical effect of various strategies of cognitive rehabilitation and strategies for aphasia and dysarthria is scarce. Several large trials of rehabilitation practice and of novel therapies (eg, stem-cell therapy, repetitive transcranial magnetic stimulation, virtual reality, robotic therapies, and drug augmentation) are underway to inform future practice.

      Monday, November 11, 2019

      Step training with body weight support: Effect of treadmill speed and practice paradigms on poststroke locomotor recovery

      With no controls you can't tell if this is the placebo effect, the Hawthorne effect, or the training. Bad research.

      Step training with body weight support: Effect of treadmill speed and practice paradigms on poststroke locomotor recovery

      Katherine J. Sullivan, PhD, PT, Barbara J. Knowlton, PhD, Bruce H. Dobkin, MD
      ABSTRACT. Sullivan KJ, Knowlton BJ, Dobkin BH. Step training with body weight support: effect of treadmill speed and practice paradigms on post stroke locomotor recovery. Arch Phys Med Rehabil 2002;83:683-91.
      Objective:
       To investigate the effect of practice paradigms that varied treadmill speed during step training with bodyweight support in subjects with chronic hemiparesis after stroke.
      Design:
       Randomized, repeated-measures pilot study with 1-and 3-month follow-ups.
      Setting:
       Outpatient locomotor laboratory.
      Participants:
       Twenty-four individuals with hemiparetic gait deficits whose walking speeds were at least 50% below normal.
      Intervention:
       Participants were stratified by locomotor se-verity based on initial walking velocity and randomly assigned to treadmill training at slow (0.5mph), fast (2.0mph), or variable (0.5, 1.0, 1.5, 2.0mph) speeds. Participants received 20minutes of training per session for 12 sessions over 4 weeks.
      Main Outcome Measure:
       Self-selected overground walking velocity (SSV) was assessed at the onset, middle, and end of training, and 1 and 3 months later.
      Results:
       SSV improved in all groups compared with base-line (P<.001). All groups increased SSV in the 1-month follow-up (P<.01) and maintained these gains at the 3-monthfollow-up (P.77). The greatest improvement in SSV across training occurred with fast training speeds compared with the slow and variable groups combined (P=.04). Effect size (ES)was large between fast compared with slow (ES=
      .75) and variable groups (ES=.73).
      Conclusions:
       Training at speeds comparable with normal walking velocity was more effective in improving SSV than training at speeds at or below the patient’s typical over ground walking velocity.
      Key Words:
       Locomotion skills; Recovery of function; Re-habilitation.©
       2002 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and  Rehabilitation

      Tuesday, October 1, 2019

      How much exercise does the enhanced gait-oriented physiotherapy provide for chronic stroke patients?

      With no controls you can't tell if this is the placebo effect, the Hawthorne effect, or the training. Bad research.

       


      How much exercise does the enhanced gait-oriented physiotherapy provide for chronic stroke patients?

      S.H.Peurala,MSc.,PT (

      ) · K.Pitkänen · J.Sivenius · I.M.TarkkaBrain Research and Rehabilitation CenterNeuronKortejoki71130 Kuopio,FinlandTel.:+358-17/460111Fax:+358-17/460200E-Mail:sinikka.peurala@neuron.fi

       Abstract

       Background and Purpose
      Physical exercise therapy in sensorimotor rehabilitation of stroke patients includes active and repetitive exercise and task-specific training.The time spent in activepractice is fundamental.The purpose of this study was to analyse what was the actual amount of exercise and content of the performed exercise of the three-week gait-oriented physiotherapy program for chronic stroke patients in an inpatient setting.
       Methods
      Twenty ambulatory post-stroke patients participated in an inpatient rehabilitation period during which a special effort was made to enhance gait training and the amount of therapy and its contents were recorded in structured form. Baseline and post intervention gait ability assessments were made, but the analysis concentrated on participation records in different forms of therapy.
      Results
      Patients received 19 hours of instructed physiotherapy in three weeks and together with self-initiated training they practised for 28 hours.The practice time in the upright position was 62% of the total duration of the instructed physiotherapy and 35% was performed while sitting. This amount of exercise resulted in improvement of the gait tests.
      Conclusions
      In order to improve gait in the chronic state of disease,a sufficient amount of gait rehabilitation practice can be obtained with a combination of electromechanical gait trainer exercises, physiotherapy, instructed exercise groups and self-initiated training.

      Key words
      motor rehabilitation· gait · weight-supported training ·cerebrovascular diseases ·hemiparesis

      Wednesday, June 26, 2019

      Unsalted tomato juice may help lower heart disease risk

      With no controls you can't tell if this is the placebo effect, the Hawthorne effect, or the tomato juice.

      Unsalted tomato juice may help lower heart disease risk

      Newswise | June 06, 2019
      In a study published in Food Science & Nutrition, drinking unsalted tomato juice lowered blood pressure and low-density lipoprotein (LDL) cholesterol in Japanese adults at risk of cardiovascular disease.

      In the study, 184 male and 297 female participants were provided with as much unsalted tomato juice as they wanted throughout 1 year. At the end of the study, blood pressure in 94 participants with untreated prehypertension or hypertension dropped significantly: systolic blood pressure lowered from an average of 141.2 to 137.0 mmHg, and diastolic blood pressure lowered from an average of 83.3 to 80.9 mmHg. LDL cholesterol levels in 125 participants with high cholesterol decreased from an average of 155.0 to 149.9 mg/dL. These beneficial effects were similar among men and women and among different age groups.
      "To the best of our knowledge, the current study is the first to investigate the effects of tomato or tomato product intake on cardiovascular disease risk markers over the course of a year and over a wide age range," the authors wrote.
      To read more, click here.