3 Anti-Inflammatory Ingredients To Add To Your Morning Coffee by mindbodygreen

 I just add whole milk for all the benefits of dairy fat.

dairy fat (38 posts to April 2016)

3 Anti-Inflammatory Ingredients to Add to Your Morning Coffee

Spice-Medication Interactions: What Every Clinician Needs to Know

 

 Is your competent? doctor ensuring your gut microbiome is optimal? NO? Like usual, knowing and doing nothing to ensure your 100% recovery! Make sure your supplement use is included in your doctors' analysis. 

Spice-Medication Interactions: What Every Clinician Needs to Know

Spices have been valued for centuries in Ayurvedic and Chinese medicine because of their healing properties. In small amounts used for cooking, cinnamon, turmeric, and ginger are generally safe and may provide health benefits, depending on their quality and preparation. However, at higher therapeutic doses, they can interact with medications or cause side effects; therefore, long-term use should be monitored by a healthcare professional.

Cinnamon

Cinnamon spice is extracted from the bark of various species of the cinnamon tree, and essential cinnamon oil is obtained from the bark or leaves. Active constituents include cinnamaldehyde, eugenol, and coumarin. Cinnamon provides antioxidant, anti-inflammatory, antimicrobial, antiviral, antihypertensive, blood sugar-regulating, and antitumor properties, which may reduce the risk for heart disease and improve brain function. Traditionally, it has also aided digestion and fought infections.

Combined with lysozyme, essential oils from Cinnamomum verum and clove (Syzygium aromaticum) have been shown to reduce the minimum inhibitory concentrations of gentamicin and imipenem against multidrug-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae, thereby enhancing antibiotic efficacy and modifying resistance. Its use in patients with breast cancer could be promising, but further studies are needed.

However, an in vitro study showed that cinnamaldehyde activates receptors that increase the excretion of certain drugs, potentially reducing their effectiveness. The cheaper Asian cassia cinnamon contains larger amounts of coumarin than the more expensive Ceylon cinnamon; in high doses, coumarin can damage the liver and, in combination with anticoagulants, can increase the risk for bleeding.

Interactions may occur with painkillers, antidepressants, chemotherapeutic agents, and antidiabetic drugs. Reported side effects include gastrointestinal symptoms, headaches, and skin reactions, such as dermatitis or worsening rosacea.

Turmeric

Turmeric contains the curcuminoid curcumin, the yellow component of curry powder, masala, and golden milk, prized for its anti-inflammatory and antioxidant properties and, at therapeutic doses, its anticarcinogenic and analgesic effects. Other compounds may also contribute to the observed cognitive benefits. Caution is advised when extrapolating scientific results from laboratory and animal experiments to humans, particularly because the amounts used in these studies are impractical compared with concentrated curcuminoid curcumin extracts.

Curcumin interacts with liver enzymes and may affect antidepressants, antihypertensives, chemotherapeutic agents, and certain antibiotics. Its blood-thinning, blood sugar-lowering, and blood pressure-reducing properties can potentiate the effects of anticoagulants, antidiabetics, insulin, and antihypertensives. Concurrent intake of iron-rich foods can reduce curcumin’s bioavailability.

To ensure adequate absorption, curcumin should be consumed with fats and piperine-rich black or long pepper, as well as with chili, lemon, ginger, honey, or even cinnamon and nutmeg. The preparation methods are crucial: Cooked roots may offer stronger DNA-protective effects, roasting in ghee may benefit the gut microbiome and compound uptake, and oxidation should be avoided.

At therapeutic concentrations, curcumin is contraindicated in gallstones, cholestasis, bleeding disorders or anticoagulation, and during pregnancy and breastfeeding.

Ginger

Ginger is known for its anti-inflammatory, immune-boosting, and antiemetic effects. Some studies suggest blood sugar- and blood lipid-lowering properties, but the extent of interactions with antidiabetic drugs and possible side effects — similar to those of sulfonylureas — requires further research. Ginger is already included in combination products for the treatment of diabetes.

Its active constituents, such as gingerol, have blood-thinning effects when consumed regularly, chronically, or in concentrated form and can increase bleeding risk when taken with anticoagulants. Higher doses can cause gastrointestinal side effects such as mucosal irritation, bloating, and heartburn.

Conclusion

Laboratory studies have indicated potential drug interactions for these spices, but the findings mainly involve high doses rather than typical culinary use. Caution is advised before starting such supplements, particularly in patients taking anticoagulants, antidiabetics, or chemotherapeutic agents. For most people, these spices are considered safe and combine taste with potential health benefits.

This story was translated from Univadis Germany.

Here’s How You Can Add More Flavor and Brain Health Benefits to Your Diet with Common Spices by Debbie Hampton

If your doctor has nothing on this maybe you want to ask when they will become competent in stroke rehab. Don't do anything with this until your doctor approves, which will be never. Good luck. 

Here’s How You Can Add More Flavor and Brain Health Benefits to Your Diet with Common Spices

Pepper and cinnamon improve cold induced cognitive impairment via increasing non-shivering thermogenesis; a study

Does your doctor have enough brain cells to get this added to your diet protocol regardless of body temperature?

Found this by reading the book; This is Your Brain on Food by Uma Naidoo, MD, page 129.

Pepper and cinnamon improve cold induced cognitive impairment via increasing non-shivering thermogenesis; a study

 

Chaitanya Pandit

,

S. Sai Latha

,

T. Usha Rani

&

K. R. Anilakumar

Pages 518-527 | Received 31 Mar 2018, Accepted 09 Aug 2018, Published online: 13 Sep 2018

• Download citation
• https://doi.org/10.1080/02656736.2018.1511835
• CrossMark

In this article

• Abstract
• 1. Introduction
• 2. Materials and methods
• 3. Results
• 4. Discussion
• Acknowledgements
• Additional information
• References

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Abstract

Despite an understanding that a major effect of cold exposure is a fall in core body temperature which is responsible for the observed decrements in the performance, it is surprising that thermogenic supplements are seldom evaluated to verify if they can aid in improving the performance during cold exposure. Following evidence from our previous study indicating the ability of pepper and cinnamon to improve cold endurance, we investigated further here if the improved endurance had advantages in real time where they could positively affect cognitive performance (assessed by Novel object test) when exposed to cold in albino wistar rats. In order to delineate if the observed improvement if any, was due to their cognitive enhancing ability or thermogenic potential, distinctive room temperature (RT) and cold temperature (CT) groups were used. Cold exposure impaired cognitive performance which improved following treatment with both the spices. We noted an increased rate of cold adaptive thermogenesis in CT treated group as evidenced by an elevated norepinephrine, free fatty acid levels in blood, increased expression of UCP1 in brown adipose tissue, the net effect being a decreased fall in the core body temperature. Absence of any notable effect in these parameters in the RT treated group ascertained that at least in the current experimental set up the observed improvement in performance in CT treated group is due to the thermogenic potential of the spices alone. In conclusion, our results demonstrate that the cognitive impairment caused by exposure to cold can be effectively countered by agents with thermogenic potential.

Blood pressure woes

 I'm currently taking 60 mg. Nifediprine, it seems to control it pretty well, 140/80 on most of my blood donations. My last doctor visit it was 157/80 so she increased the dose to 90 mg. To use up my old bottle I started splitting tablets. On the second day of the new dose I went for my normal 1-2 hour walk in the woods. At the farthest point I sat down on a log to rest. Upon standing up and walking 10 yards my head started swimming. Luckily I staggered my way back to the log to sit down. That lasted a couple minutes until it was either lay down on my own or fall off the log. I chose laying down, spent about 20 minutes down there until my head cleared and walked the 25 minutes home. Upon discussions with a friend of mine we decided I was dehyrated and the increased dose caused my blood pressure to not be enough to move my blood into my brain sufficiently. If I do have such thick blood that would explain why twice while donating blood they had to stop because I plugged up the needle. So now a couple of glasses of water in the morning. Sometime in the past 14 years with all the testing and doctors seen I should have been told of this problem.

And maybe some of these, but not until you talk to your doctor. I won't but that is just me.

Blood-thinning foods, drinks, and supplements

1. Turmeric

People have long used the golden spice known as turmeric for culinary and medicinal purposes. The active ingredient in turmeric is curcumin that has anti-inflammatory and blood-thinning or anticoagulant properties.

A study published in 2012 suggests that taking a daily dose of turmeric spice may help people maintain the anticoagulant status of their blood.

People can add turmeric to curries and soups or mix it with hot water to make a comforting tea.

2. Ginger

Ginger is another anti-inflammatory spice that may stop blood clotting. It contains a natural acid called salicylate. Aspirin (acetylsalicylic acid) is a synthetic derivative of salicylate and a potent blood thinner.

To get the anticoagulant effects of natural salicylates, people may want to use fresh or dried ginger regularly in baking, cooking, and juices.

It is unlikely, however, that natural salicylates are as effective as blood-thinning medications.

A 2015 analysis of 10 studies also suggests that ginger’s effects on blood clotting are unclear. It indicates that more research is needed to understand the potential blood-thinning properties of ginger fully.

3. Cayenne peppers

Cayenne peppers are also high in salicylates and can act as powerful blood-thinning agents.

Cayenne pepper is quite spicy, however, and many people can only tolerate it in small amounts.

Capsules containing cayenne pepper are available in health food stores and online. Other benefits of this spice include lowering blood pressure, increasing circulation, and reducing pain sensations.

4. Vitamin E

Vitamin E reduces blood clotting in a few different ways. These effects depend on the amount of vitamin E that a person takes. The National Institutes of Health’s Office of Dietary Supplements suggest that people who are taking blood-thinning drugs should avoid taking large doses of vitamin E.

It is unclear how much vitamin E thins the blood, although it is likely that people would need to take more than 400 International Units (IU) per day. Taking high doses of vitamin E supplements, for example, above 1,500 IU daily, on a long-term basis, may have negative effects.

It may be safer to get vitamin E from foods rather than supplements. Foods that contain vitamin E include:

• almonds
• safflower oil
• sunflower oil
• sunflower seeds
• wheat germ oil
• whole grains

5. Garlic

Besides its often desirable taste in food and cooking, garlic has natural antibiotic and antimicrobial properties.

Some research reports that odorless garlic powder demonstrates antithrombotic activities. An antithrombotic agent is a substance that reduces blood clot formation.

Another review of several studies on garlic suggests that it may thin the blood, although the effects are small and short-lived.

The American Academy of Family Physicians nonetheless recommend that people stop taking high doses of garlic 7 to 10 days before a planned surgery because of its antithrombotic properties.

6. Cassia cinnamon

Cinnamon contains coumarin, a powerful blood-thinning agent. Warfarin, the most commonly used blood-thinning drug, is derived from coumarin.

Chinese cassia cinnamon contains a much higher coumarin content than Ceylon cinnamon. Taking coumarin-rich cinnamon on a long-term basis can, however, cause liver damage.

It may be best to stick to small amounts of cinnamon in the diet in addition to using other natural blood thinners.

7. Ginkgo biloba

Practitioners of traditional Chinese medicine have used leaves from the Ginkgo biloba tree for thousands of years. Ginkgo is also a very popular herbal supplement in the United States and Europe. People take it for blood disorders, memory problems, and low energy.

Gingko thins the blood and has fibrinolytic effects, according to some sources. This means it may dissolve blood clots. One study reports that ginkgo extract has similar effects to streptokinase, a drug used to treat blood clots.

The research was, however, done in a laboratory, and not carried out on people or animals. Further research is necessary to see if gingko has the same effects in the human body.

8. Grape seed extract

There is some evidence to suggest that grape seed extract may have potential benefits for several heart and blood conditions.

It contains antioxidants that may protect the blood vessels and prevent high blood pressure.

Grape seed extract may also act as a natural blood thinner. Because of these effects, the National Center for Complementary and Integrative Health suggest that people with blood disorders, those taking blood-thinning medications, and people about to have an operation should not take grape seed extract.

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9. Dong quai

Dong quai, also known as female ginseng, is another traditional Chinese herb that may reduce blood clotting.

Studies on animals report that dong quai significantly increases the length of time it takes blood to clot (prothrombin time).

This effect may result from dong quai’s coumarin content, the same substance that makes cinnamon such a potent anticoagulant.

Dong quai is taken orally, and can be consumed as part of a herbal tea or soup.

10. Feverfew

Feverfew is a medicinal herb that comes from the same family as daisies or the Asteraceae family.

People take feverfew for migraines, some digestive disorders, and fever.

Feverfew may also act as a blood thinner by inhibiting the activity of platelets and preventing blood clotting. Feverfew is available in capsule or liquid form.

11. Bromelain

Bromelain is an enzyme that people extract from pineapples. It may be an effective remedy for cardiovascular diseases and high blood pressure.

Research suggests that bromelain can thin the blood, break down blood clots, and reduce clot formation. The enzyme also has anti-inflammatory properties.

Bromelain is available in supplement form from health stores and drug stores.

Takeaway

Many natural substances may reduce clotting to some degree. But natural remedies are unlikely to be as effective as blood-thinning drugs and people at risk of blood clots should not use them instead of prescription medications.

Government authorities do not monitor herbs and supplements as closely as food and drugs. People should research the different brands carefully before buying to ensure they are known for quality and purity.

People taking prescription blood thinners should not use natural remedies without talking to their doctor first.

Even though they are natural, some substances and foods may thin the blood too much, especially when taken in conjunction with medications. This can increase the risk of bleeding.

While people can usually consume foods with potential blood-thinning properties safely in reasonable amounts, it is essential to speak to a doctor before trying herbal remedies, such as dong quai and grape seed extract.

Some of the natural blood thinners listed in this article are available for purchase online.

Some of these products should not be taken alongside blood thinning medication.

 

11 Foods That Help Unclog Arteries and Prevent Heart Attack

Useless, not a single one gives you amounts. 

11 Foods That Help Unclog Arteries and Prevent Heart Attack

11. Chia Seeds

Once used by Ancient Aztec warriors, this tiny seed packs a super health punch. Incorporating chia seeds into your diet is an easy way to manage your cholesterol levels. Chia seeds help maintain healthy serum lipid levels. Thanks to the presence of phenolic acid and omega 3 and omega 6 oils! Phenolic acids work as an antioxidant, which prevents cellular damage from free radicals in the body. Omega 3 and omega 6 oils prevent blood clotting and inflammation. Excessive inflammation can result in heart disease and diabetes. Add some chia seeds to your smoothie, cereal, oatmeal, or salad today!

10. Avocado

Avocados are all the rage right now because they are not only tasty but they are packed with almost 20 vitamins and minerals. Like their yellow friend, bananas, avocados are rich in potassium; potassium helps regulate and control blood pressure. Keeping your blood pressure at a healthy level for your age, height, and weight is essential in preventing a heart attack. Avocados are low in sugar and rich in fiber thus they keep you full between meals. Whether eaten as a spread on toast, as a dip in guacamole or sliced onto a salad there is no wrong way to enjoy avocado.

9. Fish

An excellent alternative to red meat and poultry, fish is a low-fat and high-quality protein. Full of heart-healthy omega 3 fatty acids, vitamin B2, vitamin D, iron, zinc, iodine, magnesium, and potassium, fish is another super food. The vitamins and minerals in fish can lower blood pressure, reduce the chance of stroke, as well as prevent heart attacks. The omega 3’s in fish aid in maintaining a healthy heart by lowering blood pressure and reducing the risk of a sudden heart attack. Fish also plays an essential role in regulating blood clots and vessel constriction. This is important if you have a history of familial blood clots or stroke caused by blood clots.

8. Coconut Oil

We all have heard how great coconut oil is for hair, skin, and nails, but a beautiful outside starts with a beautiful inside. Coconut oil really does all that! If you have been looking for oil that can help boost your good HDL levels and help lower your bad LDL levels, this is it. HDL or, high-density lipoprotein, is considered good because it is the “protective” type of cholesterol. LDL, or, low-density lipoprotein is the “bad” cholesterol. Knowing your levels of each is important before incorporating new diets or lifestyle changes. Even though saturated fat has a bad rap over the years, it is an essential fat for a healthy diet. Coconut oil should still be used sparingly as it is rich in saturated fats. Even with studies showing its cholesterol friendly benefits, it is wise to use sparingly.

7. Green Tea

Drinking green tea reduces the amount of cholesterol digested and absorbed by the body. Green tea has also been shown in certain studies to reduce the risk and development of coronary heart disease by lowering blood glucose levels and body weight. Green tea is also rich in polyphenol. It blocks cholesterol absorption in the intestines and detoxes the body from bad cholesterol. After a long day, unwind with a good book and hot cup of heart-healthy green tea.
Related: 11 Useful Remedies Hidden In A Tea Bag

6. Broccoli

Oh, broccoli, every child’s worst nightmare. Hopefully, at this point in life, you have expanded your palette because broccoli is not only delicious, it’s great for your heart. Broccoli is an excellent source of vitamin K. It prevents the hardening of your arteries. Sulforaphane, which is found in raw broccoli, has shown to decrease inflammation and reduce blood pressure. Broccoli is also rich in fiber which helps keep you full longer and prevents snacking in between meals. Fiber also has been shown to promote healthy digestion and healthy digestion is the key to staying regular. Eating broccoli raw is the best way to get all the nutritional benefits this vegetable has to offer. If you do not enjoy raw broccoli, try lightly steaming it and using nutritional yeast for flavor.

5. Cinnamon

You don’t have to do the cinnamon challenge that swept the Internet to get the nutritional benefits from this simple spice. Just one teaspoon added to your daily coffee, oatmeal, smoothie, or cereal along with a healthy diet and exercise plan could reduce your cholesterol levels. Cinnamon also increases blood circulation, which ultimately prevents blood clots that lead to heart attack. Just a dash of cinnamon can provide you with the antioxidants necessary to fight free radicals in the body. Some people do experience a slight sensitivity to the spice in cinnamon, but it is important to remember that only 5-6 grams a day are what is recommended to reap the health benefits.
Related: Lower Your Blood Sugar Level Instantly with These Foods

4. Asparagus

 Asparagus is often known as the vegetable that makes your urine smell funny. The good news is, only you can smell that strange smell when you urinate after eating asparagus. There is no bad news about asparagus; it is all positive! Since asparagus is rich in folate and other B vitamins, it helps to regulate and lower homocysteine levels in the body. Homocysteine is an amino acid found in meat, and high levels of it are linked to heart disease. Chomping on asparagus is not enough to completely reverse the adverse side effects caused by consuming heavy amounts of meat. However, it has been shown to regulate the amino acid that has been linked to heart disease. Try swapping out your regular buttered asparagus with something more heart healthy like coconut oil or olive oil.

3. Turmeric

Don’t be put off by the bright, natural color of Turmeric because it is jam-packed with heart-healthy benefits. The chemical curcumin and other naturally occurring chemicals in Turmeric decrease swelling and inflammation in some. Excess inflammation can cause heart disease, stroke, or heart attack over an extended period of time. You can add turmeric to soups, meats, poultry, fish, and smoothies. A hot new trend hitting the scene recently has been turmeric lattes. Why not step a bit outside of your comfort zone and try a turmeric latte today?
Related: Turmeric Health Benefits

2. Persimmons

Hot on the scene in the produce section is the humble persimmon. Native to China the persimmon has a soft, fibrous texture and a light but tangy taste. According to a study on tropical fruits, which included persimmons, they found that this simple fruit could improve lipid metabolism and prevent the oxidation of LDL cholesterol. Compared to tropical fruits like pineapple, mango, and guava, persimmons proved to be the healthiest for managing cholesterol levels.  Persimmons also contain high levels of fiber as well as high levels of polyphenols and tannins. Both polyphenols and tannins are an excellent source of antioxidants. By adding persimmons to your grocery list, you might lower your risk of heart disease or heart attack.

1. Spirulina

Spirulina is an algae-based supplement loaded with vitamins and nutrients your body needs. Phycocyanin, the compound that gives spirulina its pigmentation, has antihypertensive effects. Spirulina reverses endothelial dysfunction in metabolic syndrome; an increasingly common cause for the development of heart disease in Americans today. Spirulina also decreases LDL levels during an eight-week trial study. Since spirulina is mostly available as a powdered form, it is easy to incorporate into your everyday diet. Sprinkle some in your tea, mix with water, or add to a smoothie.

Top 10 Spices for a Healthy Brain

Will your doctor and stroke hospital do one fucking thing with this information? Or is it time once again to bury their brains/heads up their asses? Up to you how to respond, take it lying down or agitate. Nothing will get better for your children and grandchildren unless lots of people step forward and call out their stroke medical 'professionals' for doing nothing for future survivor recovery.  With no research references for this you will have to depend on your doctor for advice.
https://psychcentral.com/blog/archives/2017/02/24/top-10-spices-for-a-healthy-brain/

By Emily Waters
~ 2 min read 
Your diet plays a crucial role in your mental well being and physical health, as they are intricately connected. Have you ever thought about everyday spices that could give your brain an internal boost and reset from within to function at an optimal level?
Consider adding these 10 spices below to your current diet, or better yet cook with them to improve overall brain health, and help prevent, or at the very least stave off future cognitive decline. These top spices have been studied extensively by world renowned psychiatrist Dr. Daniel Amen, and is widely discussed in many of his journal publications and books, including one of his latest Change Your Brain, Change Your Life. He recommends the 10 spices below to be incorporated into your every diet to have a happier and healthier brain.
Turmeric
Found in curry, turmeric contains a chemical that has been shown to decrease plaques and tangles in the brain thought to be responsible for the onset of Alzheimer’s disease.
Saffron
In 3 specific studies that Dr. Amen conducted, a saffron extract was found to be as effective as antidepressant medication in treating people with major depression, and various anxiety disorders.
Sage
There is strong scientific evidence that sage helps to improve and strengthen the hippocampus of our brains, which is responsible for memory.
Cinnamon has been shown to help regulate attention, and focus. Additionally, it helps to regulate blood sugar, which decreases the hunger hormone Ghrelin, while boosting Leptin, the satiety hormone responsible for fullness.
Basil, a common antioxidant pizza topper is responsible for improving blood flow to the heart and brain, and has additional anti inflammatory properties that offer protection from Alzheimer’s disease, and other forms of dementia.
Thyme is responsible for increasing the amount of DHA, an essential fatty acid in the brain. DHA is responsible for playing a central role in brain health. In fact, an optimal intake of DHA is especially essential for pregnant and nursing mothers to endure adequate brain development in their children.
Oregano, especially dried oregano has between 30-40 times the brain healing antioxidant power of raw blueberries, 46 times more than Quercetin that’s found in the skin of apples, and 56 times as much as strawberries, making it one of the most powerful brain cell protectors on the planet.
Garlic promotes better blood flow to the brain, and actually works by stopping/killing brain cancer cells in a 2007 study.
Ginger can potentially make you smarter. A study that combined ginger with ginkgo biloba suggests that it does, and further studies aiming to replicate those earlier findings are currently underway. Ginger root extract may also be beneficial in the treatment of Parkinson’s disease, and for those who suffer from migraine/ tension/cluster headaches.
Rosemary
A recent study highlighted the beneficial effects of rosemary in diminishing cognitive decline in people with dementia. Fresh or dried will do the trick.
Despite our genetic blueprint, a lot of things regarding our overall health are really in our hands, and specifically found in nature. Take advantage of the power you personally have by incorporating these healing spices into your diet and you will be rewarded with a happier and healthier brain in the long run.

Cinnamon may lessen damage of high-fat diet in rats

Don't do this on your own. Ask your doctor what researcher they are collaborating with to answer if this works in humans. And when that answer will be known. No collaboration, call the president up and demand that the doctor be fired for incompetence, along with the stroke department head.  We have to get to the point where our doctors are actively trying to solve stroke problems rather than passively regurgitating knowledge from 20 years ago in medical school.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=174807&CultureCode=en

27 April 2017 American Heart Association

• Under embargo until 06 May 2017 13:30 GMT

Cinnamon may lessen the risk of cardiovascular damage of a high-fat diet by activating the body’s antioxidant and anti-inflammatory systems and slowing the fat-storing process, according to a preliminary animal study presented at the American Heart Association’s Arteriosclerosis, Thrombosis and Vascular Biology | Peripheral Vascular Disease 2017 Scientific Sessions.
In the study, researchers fed rats cinnamon supplements for 12 weeks along with a high-fat diet. They found:
The rats weighed less and had less belly fat and healthier levels of sugar, insulin and fat in their blood, compared to rats that did not receive cinnamon with their high-fat foods;
Rats fed cinnamon also had fewer molecules involved in the body’s fat-storing process and more antioxidant and anti-inflammatory molecules that protect the body from the damages of stress.
The results suggest that cinnamon may reduce the effects of a high-fat diet, researchers said.
Vijaya Juturu, Ph.D., OmniActive Health Technologies Inc, Morristown, NJ.
http://newsroom.heart.org/news/cinnamon-may-lessen-damage-of-high-fat-diet-in-rats?preview=8832aa437c34afa3942dda3235df3761

• Full bibliographic informationAmerican Heart Association ATVB-PVD Scientific Sessions 2017
  Cinnamon Extract Inhibit Lipids and Inflammation by Modulation of Transcription Factors : In vivo model
  Poster Session 3 - Poster Presentation 545
  Authors/Disclosures:
  Zeynep Tuzcu N/A, Cemal Orhan, Nurhan Sahin, Kazim Sahin, Firat Univ, Elazig, Turkey; Vijaya Juturu, OmniActive Health Technologies Inc, Morristown, NJ

Your Brain on Cinnamon

Don't do this, way too dangerous until your doctor has vetted this.
https://stayingsharp.aarp.org/art/nourish/16/cinnamon-brain-benefits.html
Cinnamon is a spice that may do much more than make your food or beverages taste better. Watch "Your Brain on Cinnamon" to learn about this brain-healthy spice.

Cinnamon - Interaction of Cinnamaldehyde and Epicatechin with Tau: Implications of Beneficial Effects in Modulating Alzheimer's Disease Pathogenesis

Only 3 years old and nothing seems to have been done with this knowledge. 

Cinnamon - Interaction of Cinnamaldehyde and Epicatechin with Tau: Implications of Beneficial Effects in Modulating Alzheimer's Disease Pathogenesis 

Article type: Research Article

Authors: George, Roshni C. | Lew, John | Graves, Donald J.

Affiliations: Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA, USA

Note: [] Correspondence to: Donald J. Graves, Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA. Tel.: +1 805 893 5337; Fax: +1 805 893 5337; E-mail: djgraves5@yahoo.com

Abstract: Abnormal modifications in tau such as hyperphosphorylation, oxidation, and glycation interfere with its interaction with microtubules leading to its dissociation and self-aggregation into neurofibrillary tangles, a hallmark of Alzheimer's disease (AD). Previously we reported that an aqueous extract of cinnamon has the ability to inhibit tau aggregation in vitro and can even induce dissociation of tangles isolated from AD brain. In the present study, we carried out investigations with cinnamaldehyde (CA) and epicatechin (EC), two components of active cinnamon extract. We found that CA and the oxidized form of EC (ECox) inhibited tau aggregation in vitro and the activity was due to their interaction with the two cysteine residues in tau. Mass spectrometry of a synthetic peptide, SKCGS, representing the actual tau sequence, identified the thiol as reacting with CA and ECox. Use of a cysteine double mutant of tau showed the necessity of cysteine for aggregation inhibition by CA. The interaction of CA with tau cysteines was reversible and the presence of CA did not impair the biological function of tau in tubulin assembly in vitro. Further, these compounds protected tau from oxidation caused by the reactive oxygen species, H2O2, and prevented subsequent formation of high molecular weight species that are considered to stimulate tangle formation. Finally, we observed that EC can sequester highly reactive and toxic byproducts of oxidation such as acrolein. Our results suggest that small molecules that form a reversible interaction with cysteines have the potential to protect tau from abnormal modifications.

Keywords: Aggregation, Alzheimer's disease, cinnamaldehyde, cysteine, epicatechin, hydrogen peroxide, reactive oxygen species, tau protein

DOI: 10.3233/JAD-122113

Journal: Journal of Alzheimer's Disease, vol. 36, no. 1, pp. 21-40, 2013

Accepted 1 March 2013

|

Published: 2013

Price: EUR 27.50

Cinnamon Converts Poor Learning Mice to Good Learners: Implications for Memory Improvement

Not to be done on your own. You know how dangerous eating food is without a doctors prescription. Of course your doctor will never get around to creating a stroke food protocol, which will make no difference since you will have lost the memory of this good idea. Isn't it much better being stupid? Less to think about.
http://link.springer.com/article/10.1007/s11481-016-9693-6

• Khushbu K. Modi
• , Suresh B. Rangasamy
• , Sridevi Dasarathi
• , Avik Roy
• , Kalipada Pahan 

$39.95 / €34.95 / £29.95 *

* Final gross prices may vary according to local VAT.

Get Access

Abstract

This study underlines the importance of cinnamon, a commonly used natural spice and flavoring material, and its metabolite sodium benzoate (NaB) in converting poor learning mice to good learning ones. NaB, but not sodium formate, was found to upregulate plasticity-related molecules, stimulate NMDA- and AMPA-sensitive calcium influx and increase of spine density in cultured hippocampal neurons. NaB induced the activation of CREB in hippocampal neurons via protein kinase A (PKA), which was responsible for the upregulation of plasticity-related molecules. Finally, spatial memory consolidation-induced activation of CREB and expression of different plasticity-related molecules were less in the hippocampus of poor learning mice as compared to good learning ones. However, oral treatment of cinnamon and NaB increased spatial memory consolidation-induced activation of CREB and expression of plasticity-related molecules in the hippocampus of poor-learning mice and converted poor learners into good learners. These results describe a novel property of cinnamon in switching poor learners to good learners via stimulating hippocampal plasticity.

8 Foods That Could Help Unclog Your Arteries

You can read this but they missed a big one.

Watermelon juice reverses hardening of the arteries

 

 

http://www.onegreenplanet.org/natural-health/foods-that-could-help-unclog-your-arteries/? 

1. Garlic

2. Pomegranate

3. Turmeric

4. Chia Seeds

5. Cinnamon

6. Apples

7. Tomatoes

8. Greens