You'll have to ask your doctor about all these benefits vs. this negative article.
we found that inhaled low dose carbon monoxide was anti-inflammatory.
It reduced the amount of cell death (apoptosis), and increased levels
of the anti-apoptotic molecule BAG-1, in the placenta and additionally
increased the level of vascular endothelial growth factor (VEGF), which
is associated with angiogenesis and blood vessel repair."
Carbon Monoxide Releasing Molecule-A1 (CORM-A1) Improves Neurogenesis: Increase of Neuronal Differentiation Yield by Preventing Cell Death
Carbon monoxide may actually protect the brain from damage after subarachnoid hemorrhage
Deadly carbon monoxide prevents miscarriage
The negative article here:
Association of exhaled carbon monoxide with stroke incidence and subclinical vascular brain injury
Stroke, 02/12/2016
The
authors related exhaled carbon monoxide (CO) to magnetic resonance
imaging measures of subclinical cerebrovascular disease
cross–sectionally and to incident stroke/transient ischemic attack
prospectively in the Framingham Offspring study. In this large,
community–based sample of individuals without clinical stroke/transient
ischemic attack at baseline, higher exhaled CO was associated with a
greater burden of subclinical cerebrovascular disease cross–sectionally
and with increased risk of stroke/transient ischemic attack
prospectively. Further investigation is necessary to explore the
biological mechanisms linking elevated CO with stroke.
Methods
- The authors measured exhaled CO in 3313 participants (age 59±10 years; 53% women), and brain magnetic resonance imaging was available in 1982 individuals (age 58±10 years; 54% women).
- Participants were analyzed according to tertiles of exhaled CO concentration.
Results
- In age- and sex-adjusted models, the highest tertile of exhaled CO was associated with lower total cerebral brain volumes, higher white-matter hyperintensity volumes, and greater prevalence of silent cerebral infarcts (P<0.05 for all).
- The results for total cerebral brain volume and white-matter hyperintensity volume were consistent after removing smokers from the sample, and the association with white-matter hyperintensity volume persisted after multivariable adjustment (P=0.04).
- In prospective analyses (mean follow-up 12.9 years), higher exhaled CO was associated with 67% (second tertile) and 97% (top tertile) increased incidence of stroke/transient ischemic attack relative to the first tertile that served as referent (P<0.01 for both).
- These results were consistent in nonsmokers and were partially attenuated upon adjustment for vascular risk factors.
No comments:
Post a Comment