Alzheimer’s Drug May Help Treat Traumatic Brain Injury

9 posts going back to 2014 show memantine being useful for stroke recovery. And  yet I see nothing in the ASA, NSA or WSO about this or any reference to a memantine protocol anywhere. Once again proving we have NO stroke leadership and NO stroke strategy. Obviously, nobody cares. Your doctor doesn't care. Your stroke hospital doesn't care. You're screwed along with your children and grandchildren. Hopefully comeuppance hits the appropriate people. 

Alzheimer’s Drug May Help Treat Traumatic Brain Injury

Traumatic brain injury (TBI) is a major cause of disability and death globally, but medications have generally failed to benefit patients. A new study found that memantine, a drug that is used to treat dementia associated with Alzheimer's disease, may be a promising therapy.

The study examined the effect of memantine on blood levels of neuron-specific enolase (NSE), a marker of neuronal damage, and the Glasgow Coma Scale (GCS) in patients with moderate TBI. The GCS is the most common scoring system used to describe the level of consciousness in a person following a TBI.
Patients with moderate TBI who received memantine had significantly reduced blood levels of NSE by day 7 and marked improvements in their GCS scores on day 3 of the study.
The study is published in The Journal of Clinical Pharmacology.
Access the Paper:
http://onlinelibrary.wiley.com/doi/10.1002/jcph.980/full

• Full bibliographic informationMajid Mokhtari, MD, FCCP, Hossein Nayeb-Aghaei, MD, Mehran Kouchek, MD, Mir Mohammad Miri, MD, Reza Goharani, MD, Arash Amoozandeh, MD, Sina Akhavan Salamat, PharmD and Mohammad Sistanizad, PharmD, PhD. Effect of Memantine on Serum Levels of Neuron-Specific Enolase and on the Glasgow Coma Scale in Patients With Moderate Traumatic Brain Injury. The Journal of Clinical Pharmacology. DOI: 10.1002/jcph.980.