Deans' stroke musings: Caffeine ingestion attenuates fatigue-induced loss of muscle torque complexity

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, October 10, 2017

Caffeine ingestion attenuates fatigue-induced loss of muscle torque complexity

With a little bit of followup we could determine if caffeine helps stroke fatigue. But we don't have enough brains anywhere in the stroke medical world trying to solve ANY of the problems in stroke.
My therapists were constantly asking me if I was tired from the exertions during therapy. Caffeine administration could possibly increase the amount of therapy achieved each day. My fatigue was never from muscle activity, it was total mental fatigue.

Caffeine ingestion attenuates fatigue-induced loss of muscle torque complexity

Medicine and Science in Sports and Exercise | October 10, 2017

Pethick J, et al. - This study was performed to test the speculation that caffeine administration would attenuate the fatigue-induced loss of torque complexity. The current study showed that the caffeine ingestion slowed the fatigue-induced loss of torque complexity and increased the time to task failure during intermittent isometric contractions, in all the probability through central mechanisms.

Methods

Total 11 healthy participants performed intermittent isometric contractions of the knee extensors to task failure at a target torque of 50% maximal voluntary contraction (MVC), with a 60% duty factor (6 s contraction, 4 s rest), 1 hour after ingesting 6 mg[middle dot]kg-1 caffeine or a placebo.
In this study, torque and surface EMG signals were sampled continuously.
Complexity and fractal scaling of torque were evaluated utilizing approximate entropy (ApEn) and the detrended fluctuation analysis (DFA) [alpha] scaling exponent.
Global, central and peripheral fatigue were measured utilizing MVCs with femoral nerve stimulation.

Results

They noticed caffeine ingestion increased endurance by 30 +/- 16% (mean +/- SD, P = 0.019).
Complexity reduced in both trials (decreased ApEn, increased DFA [alpha]; both P < 0.01), as global, central and peripheral fatigue developed (all P < 0.01).
Complexity reduced significantly more slowly following caffeine ingestion (ApEn, -0.04 +/- 0.02 vs. -0.06 +/- 0.01, P = 0.004; DFA [alpha], 0.03 +/- 0.02 vs. 0.04 +/- 0.03, P = 0.024), as did the rates of global (-18.2 +/- 14.1 vs. -23.0 +/- 17.4 N.m.min-1, P = 0.004) and central (-3.5 +/- 3.4 vs. -5.7 +/- 3.9 %[middle dot]min-1, P = 0.02) but not peripheral (-6.1 +/- 4.1 vs. -7.9 +/- 6.3 N.m.min-1, P = 0.06) fatigue.