But you're missing the gorilla crossing the room, you don't tell us how many of those surviving patients got 100% recovered; the only goal in stroke! Leaving them disabled post stroke is NOT GOOD ENOUGH! You'll want full recovery when you are the 1 in 4 per WHO that has a stroke Perhaps you might want to start researching those solutions now, while you still can.
Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size
Abstract
Background
The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied.
Methods
We
assigned, in a 1:1 ratio, patients with proximal cerebral vessel
occlusion in the anterior circulation and a large infarct (as defined by
an Alberta Stroke Program Early Computed Tomographic Score of ≤5;
values range from 0 to 10) detected on magnetic resonance imaging or
computed tomography within 6.5 hours after symptom onset to undergo
endovascular thrombectomy and receive medical care (thrombectomy group)
or to receive medical care alone (control group). The primary outcome
was the score on the modified Rankin scale at 90 days (scores range from
0 to 6, with higher scores indicating greater disability). The primary
safety outcome was death from any cause at 90 days, and an ancillary
safety outcome was symptomatic intracerebral hemorrhage.
Results
A total of 333 patients were assigned to either the thrombectomy group
(166 patients) or the control group (167 patients); 9 were excluded from
the analysis because of consent withdrawal or legal reasons. The trial
was stopped early because results of similar trials favored
thrombectomy. Approximately 35% of the patients received thrombolysis
therapy. The
median modified Rankin scale score at 90 days was 4 in the thrombectomy
group and 6 in the control group(What are your EXACT SOLUTIONS to get them to 100% recovery? Don't have any? Then get the hell out of stroke!) (generalized odds ratio, 1.63; 95%
confidence interval [CI], 1.29 to 2.06; P<0.001). Death
from any cause at 90 days occurred in 36.1% of the patients in the
thrombectomy group and in 55.5% of those in the control group (adjusted
relative risk, 0.65; 95% CI, 0.50 to 0.84), and the percentage of
patients with symptomatic intracerebral hemorrhage was 9.6% and 5.7%,
respectively (adjusted relative risk, 1.73; 95% CI, 0.78 to 4.68). Eleven procedure-related complications occurred in the thrombectomy group.
Conclusions
In
patients with acute stroke and a large infarct of unrestricted size,
thrombectomy plus medical care resulted in better functional outcomes
and lower mortality than medical care alone but led to a higher
incidence of symptomatic intracerebral hemorrhage. (Funded by
Montpellier University Hospital; LASTE ClinicalTrials.gov number, NCT03811769.)
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